Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2006 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/6853 |
Resumo: | p.17-21 |
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Braga, Eduardo LorensLyra, André CastroOliveira, Fabrizio NeyNascimento, LourianneSilva, AdrianoBrites, CarlosMarbak, RosicreuzaLyra, Luiz Guilherme CostaRibeiro Neto, Manuel L.Shah, Koonj AsvinBraga, Eduardo LorensLyra, André CastroOliveira, Fabrizio NeyNascimento, LourianneSilva, AdrianoBrites, CarlosMarbak, RosicreuzaLyra, Luiz Guilherme CostaRibeiro Neto, Manuel L.Shah, Koonj Asvin2012-10-03T14:24:24Z2012-10-03T14:24:24Z2006-021413-8670http://www.repositorio.ufba.br/ri/handle/ri/6853v. 10, n. 1p.17-21Co-infection with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) is increasingly common and affects the clinical course of chronic hepatitis C. Highly active antiretroviral therapy has improved the life expectancy of HIV infected patients, but, by extending survival, it permits the development of HCV cirrhosis. This study tried to evaluate clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV. We evaluated 134 HCV-infected patients: i) group A – 65 co-infected HCV/HIV patients, ii) group B – 69 mono-infected HCV patients. The impact of HIV infection on HCV liver disease was analyzed using Child's score, ultrasound findings and liver histology. Patients were subjected to HCV genotyping and anti-HBs dosage. Patients mean age was 42.4 years (±9.1) and 97 (72.4%) were males. Injected drug use and homo/bisexual practice were more frequently encountered in the co-infected group: 68.3% and 78.0%, respectively. Antibodies against hepatitis B virus (anti-HBs) were found in only 38.1% of the patients (66.7% group A x 33.3% group B). Ten out of 14 individuals (71.4%) who had liver disease (Child B or C) and 25 out of 34 (73.5%) who showed ultrasound evidence of chronic liver disease were in the co-infection group. HCV genotype-2/3 was more frequently encountered in co-infected patients (36.9% group A vs. 21.8% group B). Conclusions: a) HIV infection seems to adversely affect the clinical course of chronic hepatitis C, b) injected drug use, bi/homosexual practice and genotype-2/3 were more frequently encountered in co-infected patients, c) immunization against HBV should be encouraged in these patients.Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-10-03T14:24:24Z No. of bitstreams: 1 Eduardo Lorens, Braga.pdf: 40671 bytes, checksum: a5941834761ed04d40e0319bdcad047c (MD5)Made available in DSpace on 2012-10-03T14:24:24Z (GMT). No. of bitstreams: 1 Eduardo Lorens, Braga.pdf: 40671 bytes, checksum: a5941834761ed04d40e0319bdcad047c (MD5) Previous issue date: 2006-02SalvadorThe Brazilian Journal of Infectious Diseases and Contexto Publishinghttp://dx.doi.org/10.1590/S1413-86702006000100004reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHepatitis CHIVCo-infectionClinical courseHCV genotypeClinical and epidemiological features of patients with chronic hepatitis C co-infected with HIVBrazilian Journal of Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6853/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINALEduardo Lorens, Braga.pdfEduardo Lorens, Braga.pdfapplication/pdf40671https://repositorio.ufba.br/bitstream/ri/6853/1/Eduardo%20Lorens%2c%20Braga.pdfa5941834761ed04d40e0319bdcad047cMD51TEXTEduardo Lorens, Braga.pdf.txtEduardo Lorens, Braga.pdf.txtExtracted texttext/plain27118https://repositorio.ufba.br/bitstream/ri/6853/3/Eduardo%20Lorens%2c%20Braga.pdf.txtdc1d3ecc907c98b1c0abf491c2ad05c8MD53ri/68532022-07-05 14:03:08.665oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:08Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV |
| dc.title.alternative.pt_BR.fl_str_mv |
Brazilian Journal of Infectious Diseases |
| title |
Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV |
| spellingShingle |
Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV Braga, Eduardo Lorens Hepatitis C HIV Co-infection Clinical course HCV genotype |
| title_short |
Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV |
| title_full |
Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV |
| title_fullStr |
Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV |
| title_full_unstemmed |
Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV |
| title_sort |
Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV |
| author |
Braga, Eduardo Lorens |
| author_facet |
Braga, Eduardo Lorens Lyra, André Castro Oliveira, Fabrizio Ney Nascimento, Lourianne Silva, Adriano Brites, Carlos Marbak, Rosicreuza Lyra, Luiz Guilherme Costa Ribeiro Neto, Manuel L. Shah, Koonj Asvin |
| author_role |
author |
| author2 |
Lyra, André Castro Oliveira, Fabrizio Ney Nascimento, Lourianne Silva, Adriano Brites, Carlos Marbak, Rosicreuza Lyra, Luiz Guilherme Costa Ribeiro Neto, Manuel L. Shah, Koonj Asvin |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Braga, Eduardo Lorens Lyra, André Castro Oliveira, Fabrizio Ney Nascimento, Lourianne Silva, Adriano Brites, Carlos Marbak, Rosicreuza Lyra, Luiz Guilherme Costa Ribeiro Neto, Manuel L. Shah, Koonj Asvin Braga, Eduardo Lorens Lyra, André Castro Oliveira, Fabrizio Ney Nascimento, Lourianne Silva, Adriano Brites, Carlos Marbak, Rosicreuza Lyra, Luiz Guilherme Costa Ribeiro Neto, Manuel L. Shah, Koonj Asvin |
| dc.subject.por.fl_str_mv |
Hepatitis C HIV Co-infection Clinical course HCV genotype |
| topic |
Hepatitis C HIV Co-infection Clinical course HCV genotype |
| description |
p.17-21 |
| publishDate |
2006 |
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2006-02 |
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2012-10-03T14:24:24Z |
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1413-8670 |
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v. 10, n. 1 |
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1413-8670 v. 10, n. 1 |
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The Brazilian Journal of Infectious Diseases and Contexto Publishing |
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The Brazilian Journal of Infectious Diseases and Contexto Publishing |
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http://dx.doi.org/10.1590/S1413-86702006000100004 |
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