Renal involvement in leptospirosis – new insights into pathophysiology and treatment

Detalhes bibliográficos
Autor(a) principal: Cerqueira, Thaís Bandeira
Data de Publicação: 2008
Outros Autores: Athanazio, Daniel Abensur, Spichler, Anne Stambovsky, Seguro, Antônio Carlos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6132
Resumo: p. 248-252
id UFBA-2_d36498a330cfb285a054fa3d5cf60534
oai_identifier_str oai:repositorio.ufba.br:ri/6132
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Cerqueira, Thaís BandeiraAthanazio, Daniel AbensurSpichler, Anne StambovskySeguro, Antônio CarlosCerqueira, Thaís BandeiraAthanazio, Daniel AbensurSpichler, Anne StambovskySeguro, Antônio Carlos2012-06-14T12:07:02Z2012-06-14T12:07:02Z20081413-8670http://www.repositorio.ufba.br/ri/handle/ri/6132v. 12, n. 3p. 248-252Acute renal failure (ARF) is one of the most common complications of leptospirosis although the causal mechanisms are still unclear. Diverse mechanisms are implicated in leptospiral nephropathy and new data supports the role of peculiar ion transport defects. Besides antibiotic therapy, ARF management in leptospirosis requires dialytic therapy which is most efficient when started early. Dialysis is the standard supportive therapy even though recent evidence suggests clinical benefit from alternative treatments such as plasmapheresis and hemofiltration. Renal recovery is achieved soon after clinical improvement. The comprehension of the primary mechanisms of renal dysfunction will be helpful in the development of additional therapeutic tools for improving supportive therapy for leptospiral nephropathy. This review discusses new insights into mechanisms implicated in leptospiral ARF and recent advances in treatment.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-06-14T12:07:02Z No. of bitstreams: 1 __www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdf: 130632 bytes, checksum: f5fe74bdd5b0c271aa80f688e05cd361 (MD5)Made available in DSpace on 2012-06-14T12:07:02Z (GMT). No. of bitstreams: 1 __www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdf: 130632 bytes, checksum: f5fe74bdd5b0c271aa80f688e05cd361 (MD5) Previous issue date: 2008http://dx.doi.org/10.1590/S1413-86702008000300016reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALeptospirosiskidney failureAcutePhysiopathologyDialysisRenal involvement in leptospirosis – new insights into pathophysiology and treatmentBRAZILIAN JOURNAL OF INFECTIOUS DISEASESinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL__www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdf__www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdfapplication/pdf130632https://repositorio.ufba.br/bitstream/ri/6132/1/__www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdff5fe74bdd5b0c271aa80f688e05cd361MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6132/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT__www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdf.txt__www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdf.txtExtracted texttext/plain29545https://repositorio.ufba.br/bitstream/ri/6132/3/__www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdf.txtcefaed4738e0ee058a9ba35e33736f1fMD53ri/61322022-07-05 14:03:20.933oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:20Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Renal involvement in leptospirosis – new insights into pathophysiology and treatment
dc.title.alternative.pt_BR.fl_str_mv BRAZILIAN JOURNAL OF INFECTIOUS DISEASES
title Renal involvement in leptospirosis – new insights into pathophysiology and treatment
spellingShingle Renal involvement in leptospirosis – new insights into pathophysiology and treatment
Cerqueira, Thaís Bandeira
Leptospirosis
kidney failure
Acute
Physiopathology
Dialysis
title_short Renal involvement in leptospirosis – new insights into pathophysiology and treatment
title_full Renal involvement in leptospirosis – new insights into pathophysiology and treatment
title_fullStr Renal involvement in leptospirosis – new insights into pathophysiology and treatment
title_full_unstemmed Renal involvement in leptospirosis – new insights into pathophysiology and treatment
title_sort Renal involvement in leptospirosis – new insights into pathophysiology and treatment
author Cerqueira, Thaís Bandeira
author_facet Cerqueira, Thaís Bandeira
Athanazio, Daniel Abensur
Spichler, Anne Stambovsky
Seguro, Antônio Carlos
author_role author
author2 Athanazio, Daniel Abensur
Spichler, Anne Stambovsky
Seguro, Antônio Carlos
author2_role author
author
author
dc.contributor.author.fl_str_mv Cerqueira, Thaís Bandeira
Athanazio, Daniel Abensur
Spichler, Anne Stambovsky
Seguro, Antônio Carlos
Cerqueira, Thaís Bandeira
Athanazio, Daniel Abensur
Spichler, Anne Stambovsky
Seguro, Antônio Carlos
dc.subject.por.fl_str_mv Leptospirosis
kidney failure
Acute
Physiopathology
Dialysis
topic Leptospirosis
kidney failure
Acute
Physiopathology
Dialysis
description p. 248-252
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2012-06-14T12:07:02Z
dc.date.available.fl_str_mv 2012-06-14T12:07:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6132
dc.identifier.issn.none.fl_str_mv 1413-8670
dc.identifier.number.pt_BR.fl_str_mv v. 12, n. 3
identifier_str_mv 1413-8670
v. 12, n. 3
url http://www.repositorio.ufba.br/ri/handle/ri/6132
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S1413-86702008000300016
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/6132/1/__www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdf
https://repositorio.ufba.br/bitstream/ri/6132/2/license.txt
https://repositorio.ufba.br/bitstream/ri/6132/3/__www.scielo.br_pdf_bjid_v12n3_a16v12n3.pdf.txt
bitstream.checksum.fl_str_mv f5fe74bdd5b0c271aa80f688e05cd361
1b89a9a0548218172d7c829f87a0eab9
cefaed4738e0ee058a9ba35e33736f1f
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1808459401237889024

Registros relacionados