Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?

Detalhes bibliográficos
Autor(a) principal: Menezes, C.
Data de Publicação: 2009
Outros Autores: Melo, Ailton de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6162
Resumo: Trabalho completo: acesso restrito, p. 673–676
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spelling Menezes, C.Melo, Ailton de SouzaMenezes, C.Melo, Ailton de Souza2012-06-15T19:23:26Z20090269-4727http://www.repositorio.ufba.br/ri/handle/ri/6162v. 34, n. 6Trabalho completo: acesso restrito, p. 673–676Objective: To assess the influence of levodopa on swallowing dysfunction in Parkinson’s disease patients. Methods: A systematic review of the literature and a meta-analysis were performed. All studies referring to levodopa and swallowing dysfunction that provided direct data or data that could be transformed into mean ± standard deviation were considered for analysis. The primary efficacy variables were Oral Transit Time (OTT),Pharyngeal Transit Time (PTT) for both thin fluids and solids, and aspiration. Results: Seven studies describing swallowing functions in PD patients using levodopa were found, and five of these matched the inclusion criteria. No clinically meaningful improvement after levodopa intake was noted. Adverse effects were not reported by the authors. Conclusion: This meta-analysis shows that levodopa intake was not associated with an improvement of swallowing dysfunction in Parkinson’s disease patients.Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-06-15T19:23:26Z No. of bitstreams: 1 (70)j.1365-2710.2009.01031.x.pdf: 260842 bytes, checksum: 27a05aef8369fd7a912920f3dd0aa5d9 (MD5)Made available in DSpace on 2012-06-15T19:23:26Z (GMT). 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dc.title.pt_BR.fl_str_mv Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?
dc.title.alternative.pt_BR.fl_str_mv Journal of Clinical Pharmacy and Therapeutics
title Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?
spellingShingle Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?
Menezes, C.
aspiration
levodopa
Parkinson’s disease
swallowing
title_short Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?
title_full Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?
title_fullStr Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?
title_full_unstemmed Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?
title_sort Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?
author Menezes, C.
author_facet Menezes, C.
Melo, Ailton de Souza
author_role author
author2 Melo, Ailton de Souza
author2_role author
dc.contributor.author.fl_str_mv Menezes, C.
Melo, Ailton de Souza
Menezes, C.
Melo, Ailton de Souza
dc.subject.por.fl_str_mv aspiration
levodopa
Parkinson’s disease
swallowing
topic aspiration
levodopa
Parkinson’s disease
swallowing
description Trabalho completo: acesso restrito, p. 673–676
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2012-06-15T19:23:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6162
dc.identifier.issn.none.fl_str_mv 0269-4727
dc.identifier.number.pt_BR.fl_str_mv v. 34, n. 6
identifier_str_mv 0269-4727
v. 34, n. 6
url http://www.repositorio.ufba.br/ri/handle/ri/6162
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Blackwell Publishing
publisher.none.fl_str_mv Blackwell Publishing
dc.source.pt_BR.fl_str_mv http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.2009.01031.x/pdf
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