Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders

Detalhes bibliográficos
Autor(a) principal: Serafini, Gianluca
Data de Publicação: 2011
Outros Autores: Pompili, Maurizio, Innamorati, Marco, Fusar-Poli, Paolo, Akiskal, Hagop S., Rihmer, Zoltan, Lester, David, Romano, Andrea, Oliveira, Irismar Reis de, Strusi, Leonardo, Ferracuti, Stefano, Girardi, Paolo, Tatarelli, Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5469
Resumo: Texto completo: acesso restrito. p.47–55.
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spelling Serafini, GianlucaPompili, MaurizioInnamorati, MarcoFusar-Poli, PaoloAkiskal, Hagop S.Rihmer, ZoltanLester, DavidRomano, AndreaOliveira, Irismar Reis deStrusi, LeonardoFerracuti, StefanoGirardi, PaoloTatarelli, RobertoSerafini, GianlucaPompili, MaurizioInnamorati, MarcoFusar-Poli, PaoloAkiskal, Hagop S.Rihmer, ZoltanLester, DavidRomano, AndreaOliveira, Irismar Reis deStrusi, LeonardoFerracuti, StefanoGirardi, PaoloTatarelli, Roberto2012-02-29T17:21:05Z20111573-2517http://www.repositorio.ufba.br/ri/handle/ri/5469v. 129.Texto completo: acesso restrito. p.47–55.Background: Patients with white matter hyperintensities (WMH) may be at higher risk for affective disorders and suicide. Affective temperaments may play a significant role in mood disorders. This study aimed to evaluate the eventual association between WMH, affective temperaments and suicidal behaviour in major affective disorder. Methods: A total of 318 patients with major affective disorders were consecutively admitted as psychiatric inpatient. A total of 247 were included and given, brain magnetic resonance imaging (MRI) and assessed with the Mini International Neuropsychiatric Interview (MINI), the Beck Hopelessness Scale (BHS), the Hamilton Depression Rating Scale (HDRS17), the Young Mania Rating Scale (YMRS) and the Temperament Evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-A). Results: A total of 48% of patients had periventricular WMH (PWMH) and 39% of them had deep WMH (DWMH). Patients with higher dysthymia and lower hyperthymia (H-DCIA group) were more likely to have higherBHS scores (BHS 9=77% vs. 52%; pN0.001),moreWMH(46% vs. 29%; 2 n=3=9.90; pb0.05), higherMINI suicidal risk (54% vs. 42%; pb0.05), and more recent suicide attempts (24% vs. 14%; pb0.05), than patients with higher hyperthymia and lower dysthymia (H-H group). Limitations: The small sample size did not allow the generalization of the present findings. Conclusions: Differences among temperament groupsmeasured by the TEMPS-Aare associatedwith differences in their MRIs, indicating that different temperament profiles are associated with differences in the subcortical structures of the brain. The implications of the resultswere discussed.Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-02-29T17:21:05Z No. of bitstreams: 1 Affective temperamental profiles are associated with white matter.pdf: 236313 bytes, checksum: 437ecb29de9d4e5412d6bfe66d2dc6dd (MD5)Made available in DSpace on 2012-02-29T17:21:05Z (GMT). No. of bitstreams: 1 Affective temperamental profiles are associated with white matter.pdf: 236313 bytes, checksum: 437ecb29de9d4e5412d6bfe66d2dc6dd (MD5) Previous issue date: 2011doi:10.1016/j.jad.2010.07.020reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBASuicidal riskMood disordersMRIAffective temperamentsPWMHDWMHAffective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disordersJournal of Affective Disordersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINALAffective temperamental profiles are associated with white matter.pdfAffective temperamental profiles are associated with white matter.pdfapplication/pdf236313https://repositorio.ufba.br/bitstream/ri/5469/1/Affective%20temperamental%20profiles%20are%20associated%20with%20white%20matter.pdf437ecb29de9d4e5412d6bfe66d2dc6ddMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5469/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTAffective temperamental profiles are associated with white matter.pdf.txtAffective temperamental profiles are associated with white matter.pdf.txtExtracted texttext/plain52176https://repositorio.ufba.br/bitstream/ri/5469/3/Affective%20temperamental%20profiles%20are%20associated%20with%20white%20matter.pdf.txt3239b52b04d5020d3b5e92966749e226MD53ri/54692022-07-05 14:02:48.328oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:48Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders
dc.title.alternative.pt_BR.fl_str_mv Journal of Affective Disorders
title Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders
spellingShingle Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders
Serafini, Gianluca
Suicidal risk
Mood disorders
MRI
Affective temperaments
PWMH
DWMH
title_short Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders
title_full Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders
title_fullStr Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders
title_full_unstemmed Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders
title_sort Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders
author Serafini, Gianluca
author_facet Serafini, Gianluca
Pompili, Maurizio
Innamorati, Marco
Fusar-Poli, Paolo
Akiskal, Hagop S.
Rihmer, Zoltan
Lester, David
Romano, Andrea
Oliveira, Irismar Reis de
Strusi, Leonardo
Ferracuti, Stefano
Girardi, Paolo
Tatarelli, Roberto
author_role author
author2 Pompili, Maurizio
Innamorati, Marco
Fusar-Poli, Paolo
Akiskal, Hagop S.
Rihmer, Zoltan
Lester, David
Romano, Andrea
Oliveira, Irismar Reis de
Strusi, Leonardo
Ferracuti, Stefano
Girardi, Paolo
Tatarelli, Roberto
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Serafini, Gianluca
Pompili, Maurizio
Innamorati, Marco
Fusar-Poli, Paolo
Akiskal, Hagop S.
Rihmer, Zoltan
Lester, David
Romano, Andrea
Oliveira, Irismar Reis de
Strusi, Leonardo
Ferracuti, Stefano
Girardi, Paolo
Tatarelli, Roberto
Serafini, Gianluca
Pompili, Maurizio
Innamorati, Marco
Fusar-Poli, Paolo
Akiskal, Hagop S.
Rihmer, Zoltan
Lester, David
Romano, Andrea
Oliveira, Irismar Reis de
Strusi, Leonardo
Ferracuti, Stefano
Girardi, Paolo
Tatarelli, Roberto
dc.subject.por.fl_str_mv Suicidal risk
Mood disorders
MRI
Affective temperaments
PWMH
DWMH
topic Suicidal risk
Mood disorders
MRI
Affective temperaments
PWMH
DWMH
description Texto completo: acesso restrito. p.47–55.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2012-02-29T17:21:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5469
dc.identifier.issn.none.fl_str_mv 1573-2517
dc.identifier.number.pt_BR.fl_str_mv v. 129.
identifier_str_mv 1573-2517
v. 129.
url http://www.repositorio.ufba.br/ri/handle/ri/5469
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv doi:10.1016/j.jad.2010.07.020
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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