Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time

Detalhes bibliográficos
Autor(a) principal: Pedroso, Célia
Data de Publicação: 2011
Outros Autores: M. Netto, Eduardo, Weyll, Neide, Brites, Carlos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/17547
Resumo: Texto completo: acesso restrito. p. 208-211
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spelling Pedroso, CéliaM. Netto, EduardoWeyll, NeideBrites, CarlosPedroso, CéliaM. Netto, EduardoWeyll, NeideBrites, Carlos2015-05-05T12:08:49Z20111525-4135http://repositorio.ufba.br/ri/handle/ri/17547v. 57, suppl. 3Texto completo: acesso restrito. p. 208-211Coinfection by HIV-1 and human lymphotropic virus type 1 is a frequent finding in South America, the Caribbean and Africa, and its prevalence varies from 4% to 16% according to the available reports. Although the impact of coinfection on HIV disease is still controversial, there is evidence supporting the contention that it can affect the natural history of both infections. No information is available on coinfection in children. In a nested case-control study, we evaluated 35 coinfected children matched by age, gender, and time of diagnosis to HIV monoinfected control subjects. At the first evaluation, coinfected children were more likely to present any signs and symptoms of disease (P < 0.001) than monoinfected ones despite having significantly higher CD4+ cells count (1429 ± 608 vs 928 ± 768 cells/mm3; P = 0.003). The proportion of deaths was higher (80%) for coinfected children than for HIV-1-infected ones (20%; relative risk, 2.1; 95% confidence interval, 1.4-3.1; P = 0.01). Survival was also significantly shorter for coinfected children (P = 0.001). Coinfection by HIV-1 and human lymphotropic vírus type 1 in Brazilian children was strongly associated with higher mortality and shorter survival time despite coinfected patients having a higher baseline CD4+ cells count.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-03-11T11:57:58Z No. of bitstreams: 1 Célia Pedroso.pdf: 137833 bytes, checksum: 099e128fbddd3df40383697f97a01c67 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-05-05T12:08:49Z (GMT) No. of bitstreams: 1 Célia Pedroso.pdf: 137833 bytes, checksum: 099e128fbddd3df40383697f97a01c67 (MD5)Made available in DSpace on 2015-05-05T12:08:49Z (GMT). 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dc.title.pt_BR.fl_str_mv Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time
dc.title.alternative.pt_BR.fl_str_mv JAIDS Journal of Acquired Immune Deficiency Syndromes
title Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time
spellingShingle Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time
Pedroso, Célia
HIV-1
HTLV-1
Coinfection
Survival
Children
title_short Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time
title_full Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time
title_fullStr Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time
title_full_unstemmed Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time
title_sort Coinfection by HIV-1 and Human Lymphotropic Virus Type 1 in Brazilian Children Is Strongly Associated With a Shorter Survival Time
author Pedroso, Célia
author_facet Pedroso, Célia
M. Netto, Eduardo
Weyll, Neide
Brites, Carlos
author_role author
author2 M. Netto, Eduardo
Weyll, Neide
Brites, Carlos
author2_role author
author
author
dc.contributor.author.fl_str_mv Pedroso, Célia
M. Netto, Eduardo
Weyll, Neide
Brites, Carlos
Pedroso, Célia
M. Netto, Eduardo
Weyll, Neide
Brites, Carlos
dc.subject.por.fl_str_mv HIV-1
HTLV-1
Coinfection
Survival
Children
topic HIV-1
HTLV-1
Coinfection
Survival
Children
description Texto completo: acesso restrito. p. 208-211
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2015-05-05T12:08:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/17547
dc.identifier.issn.none.fl_str_mv 1525-4135
dc.identifier.number.pt_BR.fl_str_mv v. 57, suppl. 3
identifier_str_mv 1525-4135
v. 57, suppl. 3
url http://repositorio.ufba.br/ri/handle/ri/17547
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.country.fl_str_mv Brasil
dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1097/QAI.0b013e31821e9baf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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