Evaluation of the transmission of Bovine Viral Diarrhea Virus by transplacental route in pregnant females experimentally inoculated

• Autor(a) principal: Zambotti, Beatriz Belloni; UNIR/EMBRAPA
• Data de Publicação: 2020
• Outros Autores: Martines, Mariela Aparecida Claro; Universidade Paulista Júlio de Mesquita Filho (UNESP) – Jaboticabal., Dreibi, Marina Lopes Mechler; Universidade Paulista Júlio de Mesquita filho (UNESP) – Jaboticabal., Storino, Gabriel Yuri; Universidade Paulista Júlio de Mesquita filho (UNESP) – Jaboticabal, Ferreira, Marcela Manduca; Universidade Paulista Júlio de Mesquita filho (UNESP) – Jaboticabal., Oliveira, Luís Guilherme de; Universidade Paulista Júlio de Mesquita filho (UNESP) – Jaboticabal
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista brasileira de higiene e sanidade animal
• Texto Completo: http://www.higieneanimal.ufc.br/seer/index.php/higieneanimal/article/view/565
• topic: BVDV, experimental inoculation, piglets, reproductive losses

Pigs, in natural conditions, can become infected with the bovine viral diarrhea virus (BVDV), a pestivirus of ruminants that leads to reproductive and economic losses. The final third of pregnancy is a critical period for gilts due to stress and the consequent immunological drop. Thus, the objective was to promote the experimental inoculation of gilts with BVDV-2 and to evaluate the capacity of virus transmission to fetuses in a critical period of stress and immunosuppression. Six pregnant gilts were inoculated between the 105th and 110th day of gestation, the piglets born underwent blood collection (to obtain whole blood and serum) and an umbilical cord fragment at birth prior to colostrum ingestion, and had blood collected weekly up to 21 days of age. Samples from all placentas were also collected. Two gilts composed the control group, and their piglets underwent the same procedures. The blood, umbilical cord and placental fragments samples were submitted to RT-PCR evaluations, while the serum was evaluated by the virus neutralization test. There was no evidence of viral transplacental transmission to fetuses in the evaluated period.