Co-infections with bovine herpesvirus type 5 and bovine viral diarrhoea virus

• Autor(a) principal: Spilki,F.R.
• Data de Publicação: 2006
• Outros Autores: Silva,T.C., Esteves,P.A., Teixeira,M.B., Batista,H.B.C.R., Chiminazzo,C., Driemeier,D., Franco,A.C., Roehe,P.M.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000500001
• topic: BoHV-5; BVDV; co-infection; experimental inoculation

During a series of experiments attempting to reproduce clinically apparent bovine herpesvirus type 5 (BoHV-5) infections, a group of calves was inadvertently infected with bovine viral diarrhoea virus (BVDV). Another group of calves was infected with BoHV-5 only. This paper reports the outcome of such infections. Two out of six calves solely infected with BoHV-5 displayed moderate to severe clinical signs. Three out of four calves of the group co-infected with BoHV-5 and BVDV developed severe clinical signs, two of them died. BoHV-5 virus was isolated to higher titres and for a longer period from the group of calves infected with both viruses. These results suggest that BVDV may enhance clinical signs induced by BoHV-5 and may also play a role in extending the period of BoHV-5 shedding.