Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment

Detalhes bibliográficos
Autor(a) principal: Lopes, Synara Cavalcante
Data de Publicação: 2019
Outros Autores: Gadelha, Daniel Duarte, Carvalho, Manuela Dias de, Fernandes, Virgínia Oliveira, Montenegro Junior, Renan Magalhães
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/42984
Resumo: Vitamin B12 is a water-soluble essential micronutrient, required by all the body cells. Its deficiency has been implicated not only in hematological and neurological disorders, but also in many metabolic processes, such as insulin resistance and body composition changes, which have aroused particular interest in recent years. This study reviews the physiology of vitamin B12 from its digestion and absorption to its distribution in tissues, metabolic effects and controversies regarding the diagnosis of deficiency, and to dietary and pharmacological treatments.
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network_name_str Repositório Institucional da Universidade Federal do Ceará (UFC)
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spelling Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatmentVitamina B12Deficiência de Vitamina B1Ácido MetilmalónicoDoenças MetabólicasSíndrome MetabólicaDiabetesVitamin B12 is a water-soluble essential micronutrient, required by all the body cells. Its deficiency has been implicated not only in hematological and neurological disorders, but also in many metabolic processes, such as insulin resistance and body composition changes, which have aroused particular interest in recent years. This study reviews the physiology of vitamin B12 from its digestion and absorption to its distribution in tissues, metabolic effects and controversies regarding the diagnosis of deficiency, and to dietary and pharmacological treatments.Revista de Medicina da UFC2019-06-24T14:01:46Z2019-06-24T14:01:46Z2019-04info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfLOPES, Synara Cavalcante et al. Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment. Rev Med UFC, Fortaleza, v. 59, n. 2, p. 40-49, abr./jun. 2019.2447-6595 (Online)http://www.repositorio.ufc.br/handle/riufc/42984Lopes, Synara CavalcanteGadelha, Daniel DuarteCarvalho, Manuela Dias deFernandes, Virgínia OliveiraMontenegro Junior, Renan Magalhãesengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-06-24T14:01:46Zoai:repositorio.ufc.br:riufc/42984Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:57:27.372183Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
title Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
spellingShingle Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
Lopes, Synara Cavalcante
Vitamina B12
Deficiência de Vitamina B1
Ácido Metilmalónico
Doenças Metabólicas
Síndrome Metabólica
Diabetes
title_short Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
title_full Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
title_fullStr Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
title_full_unstemmed Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
title_sort Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
author Lopes, Synara Cavalcante
author_facet Lopes, Synara Cavalcante
Gadelha, Daniel Duarte
Carvalho, Manuela Dias de
Fernandes, Virgínia Oliveira
Montenegro Junior, Renan Magalhães
author_role author
author2 Gadelha, Daniel Duarte
Carvalho, Manuela Dias de
Fernandes, Virgínia Oliveira
Montenegro Junior, Renan Magalhães
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lopes, Synara Cavalcante
Gadelha, Daniel Duarte
Carvalho, Manuela Dias de
Fernandes, Virgínia Oliveira
Montenegro Junior, Renan Magalhães
dc.subject.por.fl_str_mv Vitamina B12
Deficiência de Vitamina B1
Ácido Metilmalónico
Doenças Metabólicas
Síndrome Metabólica
Diabetes
topic Vitamina B12
Deficiência de Vitamina B1
Ácido Metilmalónico
Doenças Metabólicas
Síndrome Metabólica
Diabetes
description Vitamin B12 is a water-soluble essential micronutrient, required by all the body cells. Its deficiency has been implicated not only in hematological and neurological disorders, but also in many metabolic processes, such as insulin resistance and body composition changes, which have aroused particular interest in recent years. This study reviews the physiology of vitamin B12 from its digestion and absorption to its distribution in tissues, metabolic effects and controversies regarding the diagnosis of deficiency, and to dietary and pharmacological treatments.
publishDate 2019
dc.date.none.fl_str_mv 2019-06-24T14:01:46Z
2019-06-24T14:01:46Z
2019-04
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv LOPES, Synara Cavalcante et al. Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment. Rev Med UFC, Fortaleza, v. 59, n. 2, p. 40-49, abr./jun. 2019.
2447-6595 (Online)
http://www.repositorio.ufc.br/handle/riufc/42984
identifier_str_mv LOPES, Synara Cavalcante et al. Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment. Rev Med UFC, Fortaleza, v. 59, n. 2, p. 40-49, abr./jun. 2019.
2447-6595 (Online)
url http://www.repositorio.ufc.br/handle/riufc/42984
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Revista de Medicina da UFC
publisher.none.fl_str_mv Revista de Medicina da UFC
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
_version_ 1813029011762184192

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