Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da Universidade Federal do Ceará (UFC) |
Texto Completo: | http://www.repositorio.ufc.br/handle/riufc/9473 |
Resumo: | ABSTRACTPURPOSE: To evaluate the effects of acupuncture (Ac) and electroacupuncture (EAc) on oxidative stress and inflammation in testis torsion/detorsion (T/D) model in rats.METHODS: Thirty male Wistar rats were randomized into five groups. G1 Group (Sham) served as control. The remaining groups were submitted to spermatic cord torsion (720°) for 3 hours, followed by detorsion and reperfusion for 4 hours. Before detorsion G3, G4 and G5 rats were treated with Ac, EAc 2Hz and EAc 10 Hz, respectively, applied to acupoint Gulai (S-29) bilaterally under anesthesia for 5 minutes. Next, the testes were detorsioned and reperfused for 4 hours. Afterwards, blood samples and the right testis were collected for biochemical assays: reduced Glutathione (GSH), Malonaldehyde (MDA), Myeloperoxidase (MPO).RESULTS: EAc stimulation (2 and 10 Hz) promoted significant increase in concentrations of GSH in plasma and testis of G4-G5 rats, compared with G1. There was significant increase of tissue MDA in groups G4-G5 and plasma MDA in all groups, compared with G1. There was a significant reduction in MPO activity in groups G4-G5 compared with G1.CONCLUSION: Electroacupuncture stimulation (2 and 10 Hz) attenuates oxidative stress and inflammatory response in rats subjected to testicular torsion/detorsion. |
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Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in ratsTorção do Cordão EspermáticoIsquemiaEletroacupunturaABSTRACTPURPOSE: To evaluate the effects of acupuncture (Ac) and electroacupuncture (EAc) on oxidative stress and inflammation in testis torsion/detorsion (T/D) model in rats.METHODS: Thirty male Wistar rats were randomized into five groups. G1 Group (Sham) served as control. The remaining groups were submitted to spermatic cord torsion (720°) for 3 hours, followed by detorsion and reperfusion for 4 hours. Before detorsion G3, G4 and G5 rats were treated with Ac, EAc 2Hz and EAc 10 Hz, respectively, applied to acupoint Gulai (S-29) bilaterally under anesthesia for 5 minutes. Next, the testes were detorsioned and reperfused for 4 hours. Afterwards, blood samples and the right testis were collected for biochemical assays: reduced Glutathione (GSH), Malonaldehyde (MDA), Myeloperoxidase (MPO).RESULTS: EAc stimulation (2 and 10 Hz) promoted significant increase in concentrations of GSH in plasma and testis of G4-G5 rats, compared with G1. There was significant increase of tissue MDA in groups G4-G5 and plasma MDA in all groups, compared with G1. There was a significant reduction in MPO activity in groups G4-G5 compared with G1.CONCLUSION: Electroacupuncture stimulation (2 and 10 Hz) attenuates oxidative stress and inflammatory response in rats subjected to testicular torsion/detorsion.Acta Cirúrgica Brasileira2014-10-16T16:45:55Z2014-10-16T16:45:55Z2014-07info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfACIOLI, P. C. P. et al. Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats. Acta Cirúrgica Brasileira, São Paulo, v. 29, n. 7, p. 450-456, jul., 2014.1678-2674 On linehttp://www.repositorio.ufc.br/handle/riufc/9473Acioli, Porfírio Cezar PassosAlbuquerque, Andrea de OliveiraGuimarães, Isaac Bevilaqua de AlbuquerqueAraujo, Roberto Wagner Bezerra deVasconcelos, Paulo Roberto LeitãoGuimarães, Sérgio Botelhoengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2018-12-17T13:31:12Zoai:repositorio.ufc.br:riufc/9473Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:17:01.550849Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false |
dc.title.none.fl_str_mv |
Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats |
title |
Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats |
spellingShingle |
Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats Acioli, Porfírio Cezar Passos Torção do Cordão Espermático Isquemia Eletroacupuntura |
title_short |
Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats |
title_full |
Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats |
title_fullStr |
Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats |
title_full_unstemmed |
Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats |
title_sort |
Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats |
author |
Acioli, Porfírio Cezar Passos |
author_facet |
Acioli, Porfírio Cezar Passos Albuquerque, Andrea de Oliveira Guimarães, Isaac Bevilaqua de Albuquerque Araujo, Roberto Wagner Bezerra de Vasconcelos, Paulo Roberto Leitão Guimarães, Sérgio Botelho |
author_role |
author |
author2 |
Albuquerque, Andrea de Oliveira Guimarães, Isaac Bevilaqua de Albuquerque Araujo, Roberto Wagner Bezerra de Vasconcelos, Paulo Roberto Leitão Guimarães, Sérgio Botelho |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Acioli, Porfírio Cezar Passos Albuquerque, Andrea de Oliveira Guimarães, Isaac Bevilaqua de Albuquerque Araujo, Roberto Wagner Bezerra de Vasconcelos, Paulo Roberto Leitão Guimarães, Sérgio Botelho |
dc.subject.por.fl_str_mv |
Torção do Cordão Espermático Isquemia Eletroacupuntura |
topic |
Torção do Cordão Espermático Isquemia Eletroacupuntura |
description |
ABSTRACTPURPOSE: To evaluate the effects of acupuncture (Ac) and electroacupuncture (EAc) on oxidative stress and inflammation in testis torsion/detorsion (T/D) model in rats.METHODS: Thirty male Wistar rats were randomized into five groups. G1 Group (Sham) served as control. The remaining groups were submitted to spermatic cord torsion (720°) for 3 hours, followed by detorsion and reperfusion for 4 hours. Before detorsion G3, G4 and G5 rats were treated with Ac, EAc 2Hz and EAc 10 Hz, respectively, applied to acupoint Gulai (S-29) bilaterally under anesthesia for 5 minutes. Next, the testes were detorsioned and reperfused for 4 hours. Afterwards, blood samples and the right testis were collected for biochemical assays: reduced Glutathione (GSH), Malonaldehyde (MDA), Myeloperoxidase (MPO).RESULTS: EAc stimulation (2 and 10 Hz) promoted significant increase in concentrations of GSH in plasma and testis of G4-G5 rats, compared with G1. There was significant increase of tissue MDA in groups G4-G5 and plasma MDA in all groups, compared with G1. There was a significant reduction in MPO activity in groups G4-G5 compared with G1.CONCLUSION: Electroacupuncture stimulation (2 and 10 Hz) attenuates oxidative stress and inflammatory response in rats subjected to testicular torsion/detorsion. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-10-16T16:45:55Z 2014-10-16T16:45:55Z 2014-07 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
ACIOLI, P. C. P. et al. Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats. Acta Cirúrgica Brasileira, São Paulo, v. 29, n. 7, p. 450-456, jul., 2014. 1678-2674 On line http://www.repositorio.ufc.br/handle/riufc/9473 |
identifier_str_mv |
ACIOLI, P. C. P. et al. Protective effects of abdominal electroacupuncture on oxidative stress and inflammation due to testis torsion/detorsion in rats. Acta Cirúrgica Brasileira, São Paulo, v. 29, n. 7, p. 450-456, jul., 2014. 1678-2674 On line |
url |
http://www.repositorio.ufc.br/handle/riufc/9473 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Acta Cirúrgica Brasileira |
publisher.none.fl_str_mv |
Acta Cirúrgica Brasileira |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da Universidade Federal do Ceará (UFC) instname:Universidade Federal do Ceará (UFC) instacron:UFC |
instname_str |
Universidade Federal do Ceará (UFC) |
instacron_str |
UFC |
institution |
UFC |
reponame_str |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
collection |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
repository.name.fl_str_mv |
Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC) |
repository.mail.fl_str_mv |
bu@ufc.br || repositorio@ufc.br |
_version_ |
1813028737293221888 |