Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe

Detalhes bibliográficos
Autor(a) principal: Silva, Thiago Demétrio Nogueira Costa e
Data de Publicação: 2019
Outros Autores: Oliveira, Emidiana Raquel Rodrigues de Souza, Costa, Sheila Maria da Conceição, Carlos, Cláudia Isabel Silva
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/48290
Resumo: Introduction: Hypopharyngeal cancer has one of the worst prognosis of head and neck tumors. Despite advances in Oncology, disease-free survival is still low. Objective: To determine the clinical and epidemiological profiles of patients with squamous cell carcinoma of the hypopharynx, and to evaluate survival rate. Method: A retrospective study was realized by analyzing the charts of patients with the disease attended at an oncology center from 2006 to 2013. Data were analyzed by exploratory descriptive statistics. Survival was described by the Kaplan-Meier method. Results: There was a predominance of men (86.4%), mean age of 57.5 years, pardos (52.6%), farmers (38.1%), smokers (93.7%) and no history of Cancer in the family (62.5%). The most frequent initial complaint was odynophagia (45.5%). In the majority of cases, the tumor was found in the pyriform recess (50.0%), at advanced stage (95.2%), and was predominantly treated with radiotherapy associated with chemotherapy (59.1%). The mean survival of the patients was 204.5 days, while the mortality rate was 72.7%. Conclusion: The observed pattern is similar to that found in other studies. The high rates of advanced stage patients and mortality indicate a late diagnosis, which reflects the need for preventive actions.
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spelling Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringeEpidemiological and survival analysis of patients with hypopharyngeal cancerNeoplasias FaríngeasCarcinoma de Células EscamosasPerfil de SaúdeAnálise de SobrevidaIntroduction: Hypopharyngeal cancer has one of the worst prognosis of head and neck tumors. Despite advances in Oncology, disease-free survival is still low. Objective: To determine the clinical and epidemiological profiles of patients with squamous cell carcinoma of the hypopharynx, and to evaluate survival rate. Method: A retrospective study was realized by analyzing the charts of patients with the disease attended at an oncology center from 2006 to 2013. Data were analyzed by exploratory descriptive statistics. Survival was described by the Kaplan-Meier method. Results: There was a predominance of men (86.4%), mean age of 57.5 years, pardos (52.6%), farmers (38.1%), smokers (93.7%) and no history of Cancer in the family (62.5%). The most frequent initial complaint was odynophagia (45.5%). In the majority of cases, the tumor was found in the pyriform recess (50.0%), at advanced stage (95.2%), and was predominantly treated with radiotherapy associated with chemotherapy (59.1%). The mean survival of the patients was 204.5 days, while the mortality rate was 72.7%. Conclusion: The observed pattern is similar to that found in other studies. The high rates of advanced stage patients and mortality indicate a late diagnosis, which reflects the need for preventive actions.Introdução: o câncer de hipofaringe possui um dos piores prognóstico dos tumores de cabeça e pescoço. A despeito dos avanços na Oncologia, a sobrevida livre de doença ainda é baixa. Objetivo: traçar o perfil clínico e epidemiológico de pacientes com carcinoma epidermoide de hipofaringe e analisar a sobrevida. Método: foi realizado estudo retrospectivo por meio dos prontuários de pacientes com a doença atendidos em um centro de oncologia no período de 2006 a 2013. Os dados foram analisados por estatística descritiva exploratória. A sobrevida foi descrita pelo método de Kaplan-Meier. Resultados: houve predomínio de homens (86,4%), com idade média de 57,5 anos, pardos (52,6%), agricultores (38,1%), tabagistas (93,7%) e sem histórico familiar de câncer (62,5%). A queixa inicial mais relatada foi a odinofagia (45,5%). Na maioria dos casos, o tumor encontrava-se no recesso piriforme (50,0%), em estádio avançado (95,2%), sendo tratado predominantemente com radioterapia associada à quimioterapia (59,1%). A sobrevida média dos pacientes foi de 204,5 dias, enquanto que a taxa de mortalidade foi de 72,7%. Conclusão: o padrão encontrado é semelhante ao de outros estudos. A alta taxa de pacientes em estádio avançado e o alto índice de mortalidade indica diagnóstico tardio, o que reflete a necessidade de ações preventivas.Revista de Medicina da UFC2019-12-10T12:12:17Z2019-12-10T12:12:17Z2019-10info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSILVA, Thiago Demétrio Nogueira Costa e et al. Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe. Rev Med UFC, Fortaleza, v. 59, n. 4, p. 39-45, out./dez. 2019.2447-6595 (Online)http://www.repositorio.ufc.br/handle/riufc/48290Silva, Thiago Demétrio Nogueira Costa eOliveira, Emidiana Raquel Rodrigues de SouzaCosta, Sheila Maria da ConceiçãoCarlos, Cláudia Isabel Silvaporreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-12-10T12:12:17Zoai:repositorio.ufc.br:riufc/48290Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T19:02:32.732090Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe
Epidemiological and survival analysis of patients with hypopharyngeal cancer
title Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe
spellingShingle Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe
Silva, Thiago Demétrio Nogueira Costa e
Neoplasias Faríngeas
Carcinoma de Células Escamosas
Perfil de Saúde
Análise de Sobrevida
title_short Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe
title_full Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe
title_fullStr Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe
title_full_unstemmed Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe
title_sort Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe
author Silva, Thiago Demétrio Nogueira Costa e
author_facet Silva, Thiago Demétrio Nogueira Costa e
Oliveira, Emidiana Raquel Rodrigues de Souza
Costa, Sheila Maria da Conceição
Carlos, Cláudia Isabel Silva
author_role author
author2 Oliveira, Emidiana Raquel Rodrigues de Souza
Costa, Sheila Maria da Conceição
Carlos, Cláudia Isabel Silva
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva, Thiago Demétrio Nogueira Costa e
Oliveira, Emidiana Raquel Rodrigues de Souza
Costa, Sheila Maria da Conceição
Carlos, Cláudia Isabel Silva
dc.subject.por.fl_str_mv Neoplasias Faríngeas
Carcinoma de Células Escamosas
Perfil de Saúde
Análise de Sobrevida
topic Neoplasias Faríngeas
Carcinoma de Células Escamosas
Perfil de Saúde
Análise de Sobrevida
description Introduction: Hypopharyngeal cancer has one of the worst prognosis of head and neck tumors. Despite advances in Oncology, disease-free survival is still low. Objective: To determine the clinical and epidemiological profiles of patients with squamous cell carcinoma of the hypopharynx, and to evaluate survival rate. Method: A retrospective study was realized by analyzing the charts of patients with the disease attended at an oncology center from 2006 to 2013. Data were analyzed by exploratory descriptive statistics. Survival was described by the Kaplan-Meier method. Results: There was a predominance of men (86.4%), mean age of 57.5 years, pardos (52.6%), farmers (38.1%), smokers (93.7%) and no history of Cancer in the family (62.5%). The most frequent initial complaint was odynophagia (45.5%). In the majority of cases, the tumor was found in the pyriform recess (50.0%), at advanced stage (95.2%), and was predominantly treated with radiotherapy associated with chemotherapy (59.1%). The mean survival of the patients was 204.5 days, while the mortality rate was 72.7%. Conclusion: The observed pattern is similar to that found in other studies. The high rates of advanced stage patients and mortality indicate a late diagnosis, which reflects the need for preventive actions.
publishDate 2019
dc.date.none.fl_str_mv 2019-12-10T12:12:17Z
2019-12-10T12:12:17Z
2019-10
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv SILVA, Thiago Demétrio Nogueira Costa e et al. Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe. Rev Med UFC, Fortaleza, v. 59, n. 4, p. 39-45, out./dez. 2019.
2447-6595 (Online)
http://www.repositorio.ufc.br/handle/riufc/48290
identifier_str_mv SILVA, Thiago Demétrio Nogueira Costa e et al. Análise epidemiológica e da sobrevida de pacientes com câncer de hipofaringe. Rev Med UFC, Fortaleza, v. 59, n. 4, p. 39-45, out./dez. 2019.
2447-6595 (Online)
url http://www.repositorio.ufc.br/handle/riufc/48290
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Revista de Medicina da UFC
publisher.none.fl_str_mv Revista de Medicina da UFC
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
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