In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei

Detalhes bibliográficos
Autor(a) principal: Bandeira, Tereza de Jesus Pinheiro Gomes
Data de Publicação: 2013
Outros Autores: Moreira, Camila Alencar, Brilhante, Raimunda Sâmia Nogueira, Castelo-Branco, Débora de Souza Collares Maia, Araújo Neto, Manoel Paiva de, Cordeiro, Rossana de Aguiar, Rodrigues, Terezinha de Jesus Santos, Rocha, Marcos Fábio Gadelha, Sidrim, José Júlio Costa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/8552
Resumo: This study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim- sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility.
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spelling In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomalleiAmoxicilinaDoxiciclinaThis study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim- sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility.Antimicrobial agents and chemotherapy2014-07-29T14:45:16Z2014-07-29T14:45:16Z2013-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfBANDEIRA, T. J. P. G. et al. In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of brazilian strains of burkholderia pseudomallei. Antimicrobial Agents and Chemotherapy, Bethesda, v. 57, n. 11, p. 5771-3, nov. 2013.0066-4804 Impressohttp://www.repositorio.ufc.br/handle/riufc/8552Bandeira, Tereza de Jesus Pinheiro GomesMoreira, Camila AlencarBrilhante, Raimunda Sâmia NogueiraCastelo-Branco, Débora de Souza Collares MaiaAraújo Neto, Manoel Paiva deCordeiro, Rossana de AguiarRodrigues, Terezinha de Jesus SantosRocha, Marcos Fábio GadelhaSidrim, José Júlio Costaengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-01-18T18:38:04Zoai:repositorio.ufc.br:riufc/8552Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2019-01-18T18:38:04Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
title In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
spellingShingle In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
Bandeira, Tereza de Jesus Pinheiro Gomes
Amoxicilina
Doxiciclina
title_short In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
title_full In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
title_fullStr In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
title_full_unstemmed In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
title_sort In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
author Bandeira, Tereza de Jesus Pinheiro Gomes
author_facet Bandeira, Tereza de Jesus Pinheiro Gomes
Moreira, Camila Alencar
Brilhante, Raimunda Sâmia Nogueira
Castelo-Branco, Débora de Souza Collares Maia
Araújo Neto, Manoel Paiva de
Cordeiro, Rossana de Aguiar
Rodrigues, Terezinha de Jesus Santos
Rocha, Marcos Fábio Gadelha
Sidrim, José Júlio Costa
author_role author
author2 Moreira, Camila Alencar
Brilhante, Raimunda Sâmia Nogueira
Castelo-Branco, Débora de Souza Collares Maia
Araújo Neto, Manoel Paiva de
Cordeiro, Rossana de Aguiar
Rodrigues, Terezinha de Jesus Santos
Rocha, Marcos Fábio Gadelha
Sidrim, José Júlio Costa
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bandeira, Tereza de Jesus Pinheiro Gomes
Moreira, Camila Alencar
Brilhante, Raimunda Sâmia Nogueira
Castelo-Branco, Débora de Souza Collares Maia
Araújo Neto, Manoel Paiva de
Cordeiro, Rossana de Aguiar
Rodrigues, Terezinha de Jesus Santos
Rocha, Marcos Fábio Gadelha
Sidrim, José Júlio Costa
dc.subject.por.fl_str_mv Amoxicilina
Doxiciclina
topic Amoxicilina
Doxiciclina
description This study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim- sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility.
publishDate 2013
dc.date.none.fl_str_mv 2013-11
2014-07-29T14:45:16Z
2014-07-29T14:45:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv BANDEIRA, T. J. P. G. et al. In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of brazilian strains of burkholderia pseudomallei. Antimicrobial Agents and Chemotherapy, Bethesda, v. 57, n. 11, p. 5771-3, nov. 2013.
0066-4804 Impresso
http://www.repositorio.ufc.br/handle/riufc/8552
identifier_str_mv BANDEIRA, T. J. P. G. et al. In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of brazilian strains of burkholderia pseudomallei. Antimicrobial Agents and Chemotherapy, Bethesda, v. 57, n. 11, p. 5771-3, nov. 2013.
0066-4804 Impresso
url http://www.repositorio.ufc.br/handle/riufc/8552
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Antimicrobial agents and chemotherapy
publisher.none.fl_str_mv Antimicrobial agents and chemotherapy
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
_version_ 1809935806465310720

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