Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da Universidade Federal do Ceará (UFC) |
| Texto Completo: | http://www.repositorio.ufc.br/handle/riufc/5028 |
Resumo: | This study evaluated in vitro interactions of antituberculosis drugs and triazoles against Histoplasma capsulatum. Nine drug combinations, each including an antituberculosis drug (isoniazid, pyrazinamide, or ethambutol) plus a triazole (itraconazole, fluconazole, or voriconazole), were tested against both growth forms of H. capsulatum. Stronger synergistic interactions were seen in isoniazid or pyrazinamide plus triazoles for the mold form and ethambutol plus voriconazole for the yeast-like form. Further studies should evaluate these combinations in vivo. |
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Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro againstAntibióticos AntituberculoseAzóisHistoplasmaThis study evaluated in vitro interactions of antituberculosis drugs and triazoles against Histoplasma capsulatum. Nine drug combinations, each including an antituberculosis drug (isoniazid, pyrazinamide, or ethambutol) plus a triazole (itraconazole, fluconazole, or voriconazole), were tested against both growth forms of H. capsulatum. Stronger synergistic interactions were seen in isoniazid or pyrazinamide plus triazoles for the mold form and ethambutol plus voriconazole for the yeast-like form. Further studies should evaluate these combinations in vivo.Antimicrobial Agents and Chemotherapy2013-06-13T12:30:56Z2013-06-13T12:30:56Z2011-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfCAETANO, E. P. et al. Synergistic Effect of Antituberculosis Drugs and Azoles In Vitro against Histoplasma capsulatum var. capsulatum . Antimicrobial Agents and Chemotherapy, Washington, v. 55, n. 9, p. 4482-84, jun. 2011.0066-4804http://www.repositorio.ufc.br/handle/riufc/5028Caetano, Érica PachecoCordeiro, Rossana de AguiarMarques, Francisca Jakelyne de FariasBrilhante, Raimunda Sâmia NogueiraSilva, Kylvia Rocha de Castro eMourão, Charles IelpoFechine, Maria Auxiliadora BezerraRibeiro, Joyce FontelesCastelo-Branco, Débora de Souza Collares MaiaLima, Rita Amanda Chaves deRocha, Jacó Ricarte CastroRocha, Marcos Fábio GadelhaSidrim, José Júlio CostaMesquita, Jacó Ricarte LimaMonteiro, Andre Jallesengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-01-21T12:21:15Zoai:repositorio.ufc.br:riufc/5028Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:30:13.714876Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false |
| dc.title.none.fl_str_mv |
Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against |
| title |
Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against |
| spellingShingle |
Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against Caetano, Érica Pacheco Antibióticos Antituberculose Azóis Histoplasma |
| title_short |
Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against |
| title_full |
Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against |
| title_fullStr |
Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against |
| title_full_unstemmed |
Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against |
| title_sort |
Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against |
| author |
Caetano, Érica Pacheco |
| author_facet |
Caetano, Érica Pacheco Cordeiro, Rossana de Aguiar Marques, Francisca Jakelyne de Farias Brilhante, Raimunda Sâmia Nogueira Silva, Kylvia Rocha de Castro e Mourão, Charles Ielpo Fechine, Maria Auxiliadora Bezerra Ribeiro, Joyce Fonteles Castelo-Branco, Débora de Souza Collares Maia Lima, Rita Amanda Chaves de Rocha, Jacó Ricarte Castro Rocha, Marcos Fábio Gadelha Sidrim, José Júlio Costa Mesquita, Jacó Ricarte Lima Monteiro, Andre Jalles |
| author_role |
author |
| author2 |
Cordeiro, Rossana de Aguiar Marques, Francisca Jakelyne de Farias Brilhante, Raimunda Sâmia Nogueira Silva, Kylvia Rocha de Castro e Mourão, Charles Ielpo Fechine, Maria Auxiliadora Bezerra Ribeiro, Joyce Fonteles Castelo-Branco, Débora de Souza Collares Maia Lima, Rita Amanda Chaves de Rocha, Jacó Ricarte Castro Rocha, Marcos Fábio Gadelha Sidrim, José Júlio Costa Mesquita, Jacó Ricarte Lima Monteiro, Andre Jalles |
| author2_role |
author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Caetano, Érica Pacheco Cordeiro, Rossana de Aguiar Marques, Francisca Jakelyne de Farias Brilhante, Raimunda Sâmia Nogueira Silva, Kylvia Rocha de Castro e Mourão, Charles Ielpo Fechine, Maria Auxiliadora Bezerra Ribeiro, Joyce Fonteles Castelo-Branco, Débora de Souza Collares Maia Lima, Rita Amanda Chaves de Rocha, Jacó Ricarte Castro Rocha, Marcos Fábio Gadelha Sidrim, José Júlio Costa Mesquita, Jacó Ricarte Lima Monteiro, Andre Jalles |
| dc.subject.por.fl_str_mv |
Antibióticos Antituberculose Azóis Histoplasma |
| topic |
Antibióticos Antituberculose Azóis Histoplasma |
| description |
This study evaluated in vitro interactions of antituberculosis drugs and triazoles against Histoplasma capsulatum. Nine drug combinations, each including an antituberculosis drug (isoniazid, pyrazinamide, or ethambutol) plus a triazole (itraconazole, fluconazole, or voriconazole), were tested against both growth forms of H. capsulatum. Stronger synergistic interactions were seen in isoniazid or pyrazinamide plus triazoles for the mold form and ethambutol plus voriconazole for the yeast-like form. Further studies should evaluate these combinations in vivo. |
| publishDate |
2011 |
| dc.date.none.fl_str_mv |
2011-06 2013-06-13T12:30:56Z 2013-06-13T12:30:56Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
CAETANO, E. P. et al. Synergistic Effect of Antituberculosis Drugs and Azoles In Vitro against Histoplasma capsulatum var. capsulatum . Antimicrobial Agents and Chemotherapy, Washington, v. 55, n. 9, p. 4482-84, jun. 2011. 0066-4804 http://www.repositorio.ufc.br/handle/riufc/5028 |
| identifier_str_mv |
CAETANO, E. P. et al. Synergistic Effect of Antituberculosis Drugs and Azoles In Vitro against Histoplasma capsulatum var. capsulatum . Antimicrobial Agents and Chemotherapy, Washington, v. 55, n. 9, p. 4482-84, jun. 2011. 0066-4804 |
| url |
http://www.repositorio.ufc.br/handle/riufc/5028 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Antimicrobial Agents and Chemotherapy |
| publisher.none.fl_str_mv |
Antimicrobial Agents and Chemotherapy |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da Universidade Federal do Ceará (UFC) instname:Universidade Federal do Ceará (UFC) instacron:UFC |
| instname_str |
Universidade Federal do Ceará (UFC) |
| instacron_str |
UFC |
| institution |
UFC |
| reponame_str |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
| collection |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
| repository.name.fl_str_mv |
Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC) |
| repository.mail.fl_str_mv |
bu@ufc.br || repositorio@ufc.br |
| _version_ |
1813028831393480704 |