Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report

Detalhes bibliográficos
Autor(a) principal: Diniz, Renan G. M.
Data de Publicação: 2021
Outros Autores: Santos, Elaine C. dos, Chagas, Gabriel C. L., Daher, Elizabeth de Francesco
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
dARK ID: ark:/83112/001300000qqt6
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/58646
Resumo: Rationale: Dengue is the most important human arboviral disease. Neurological manifestations occur rarely in dengue. To the best of our knowledge, there is only one reported case of dengue-associated sudden sensorineural hearing loss (SSNHL) in Brazil untill now. Patient concerns: A 42-year-old man was presented to the emergency department with unconsciousness and generalized tonic clonic seizures. Diagnosis: Dengue-associated aseptic meningitis, acute kidney injury, and SSNHL. Interventions: The patient was treated with anticonvulsants and thiamine and underwent mechanical ventilation. He received combined ceftriaxone and acyclovir, which were later switched to meropenem, acyclovir and ampicillin empirically until culture results became available. He also required hemodialysis and plasmapheresis sessions and fresh frozen plasma and buffy coat transfusions until definitive diagnosis. Outcomes: The patient was discharged after improvement of his general condition and of his blood test results, but hearing loss remained. A six-month follow-up visit showed persistent deafness. Lessons: Dengue should be included in the differential diagnosis of patients from dengue-endemic areas presenting an acute febrile disease with neurological manifestations. To the best of our knowledge, this is the second reported case of dengue associated SSNHL, suggesting an association between dengue and development of SSNHL.
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spelling Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case reportDengueMeningite AssépticaMeningitis, AsepticLesão Renal AgudaAcute Kidney InjuryPerda Auditiva NeurossensorialHearing Loss, SensorineuralDeafnessSurdezRationale: Dengue is the most important human arboviral disease. Neurological manifestations occur rarely in dengue. To the best of our knowledge, there is only one reported case of dengue-associated sudden sensorineural hearing loss (SSNHL) in Brazil untill now. Patient concerns: A 42-year-old man was presented to the emergency department with unconsciousness and generalized tonic clonic seizures. Diagnosis: Dengue-associated aseptic meningitis, acute kidney injury, and SSNHL. Interventions: The patient was treated with anticonvulsants and thiamine and underwent mechanical ventilation. He received combined ceftriaxone and acyclovir, which were later switched to meropenem, acyclovir and ampicillin empirically until culture results became available. He also required hemodialysis and plasmapheresis sessions and fresh frozen plasma and buffy coat transfusions until definitive diagnosis. Outcomes: The patient was discharged after improvement of his general condition and of his blood test results, but hearing loss remained. A six-month follow-up visit showed persistent deafness. Lessons: Dengue should be included in the differential diagnosis of patients from dengue-endemic areas presenting an acute febrile disease with neurological manifestations. To the best of our knowledge, this is the second reported case of dengue associated SSNHL, suggesting an association between dengue and development of SSNHL.Asian Pacific Journal of Tropical Medicine2021-05-26T14:08:41Z2021-05-26T14:08:41Z2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfDINIZ, Renan G. M. et al. Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report. Asian Pacific Journal of Tropical Medicine, v. 14, n. 4, p. 187-190, may, 2021. Disponível em:http://www.repositorio.ufc.br/retrieve/133079/2021_art_rgmdiniz.pdf. Acesso em: 26/05/2021.1.1995-7645http://www.repositorio.ufc.br/handle/riufc/58646ark:/83112/001300000qqt6Diniz, Renan G. M.Santos, Elaine C. dosChagas, Gabriel C. L.Daher, Elizabeth de Francescoengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2022-03-04T19:38:40Zoai:repositorio.ufc.br:riufc/58646Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:15:49.892688Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report
title Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report
spellingShingle Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report
Diniz, Renan G. M.
Dengue
Meningite Asséptica
Meningitis, Aseptic
Lesão Renal Aguda
Acute Kidney Injury
Perda Auditiva Neurossensorial
Hearing Loss, Sensorineural
Deafness
Surdez
title_short Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report
title_full Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report
title_fullStr Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report
title_full_unstemmed Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report
title_sort Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report
author Diniz, Renan G. M.
author_facet Diniz, Renan G. M.
Santos, Elaine C. dos
Chagas, Gabriel C. L.
Daher, Elizabeth de Francesco
author_role author
author2 Santos, Elaine C. dos
Chagas, Gabriel C. L.
Daher, Elizabeth de Francesco
author2_role author
author
author
dc.contributor.author.fl_str_mv Diniz, Renan G. M.
Santos, Elaine C. dos
Chagas, Gabriel C. L.
Daher, Elizabeth de Francesco
dc.subject.por.fl_str_mv Dengue
Meningite Asséptica
Meningitis, Aseptic
Lesão Renal Aguda
Acute Kidney Injury
Perda Auditiva Neurossensorial
Hearing Loss, Sensorineural
Deafness
Surdez
topic Dengue
Meningite Asséptica
Meningitis, Aseptic
Lesão Renal Aguda
Acute Kidney Injury
Perda Auditiva Neurossensorial
Hearing Loss, Sensorineural
Deafness
Surdez
description Rationale: Dengue is the most important human arboviral disease. Neurological manifestations occur rarely in dengue. To the best of our knowledge, there is only one reported case of dengue-associated sudden sensorineural hearing loss (SSNHL) in Brazil untill now. Patient concerns: A 42-year-old man was presented to the emergency department with unconsciousness and generalized tonic clonic seizures. Diagnosis: Dengue-associated aseptic meningitis, acute kidney injury, and SSNHL. Interventions: The patient was treated with anticonvulsants and thiamine and underwent mechanical ventilation. He received combined ceftriaxone and acyclovir, which were later switched to meropenem, acyclovir and ampicillin empirically until culture results became available. He also required hemodialysis and plasmapheresis sessions and fresh frozen plasma and buffy coat transfusions until definitive diagnosis. Outcomes: The patient was discharged after improvement of his general condition and of his blood test results, but hearing loss remained. A six-month follow-up visit showed persistent deafness. Lessons: Dengue should be included in the differential diagnosis of patients from dengue-endemic areas presenting an acute febrile disease with neurological manifestations. To the best of our knowledge, this is the second reported case of dengue associated SSNHL, suggesting an association between dengue and development of SSNHL.
publishDate 2021
dc.date.none.fl_str_mv 2021-05-26T14:08:41Z
2021-05-26T14:08:41Z
2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv DINIZ, Renan G. M. et al. Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report. Asian Pacific Journal of Tropical Medicine, v. 14, n. 4, p. 187-190, may, 2021. Disponível em:http://www.repositorio.ufc.br/retrieve/133079/2021_art_rgmdiniz.pdf. Acesso em: 26/05/2021.1.
1995-7645
http://www.repositorio.ufc.br/handle/riufc/58646
dc.identifier.dark.fl_str_mv ark:/83112/001300000qqt6
identifier_str_mv DINIZ, Renan G. M. et al. Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: a case report. Asian Pacific Journal of Tropical Medicine, v. 14, n. 4, p. 187-190, may, 2021. Disponível em:http://www.repositorio.ufc.br/retrieve/133079/2021_art_rgmdiniz.pdf. Acesso em: 26/05/2021.1.
1995-7645
ark:/83112/001300000qqt6
url http://www.repositorio.ufc.br/handle/riufc/58646
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Asian Pacific Journal of Tropical Medicine
publisher.none.fl_str_mv Asian Pacific Journal of Tropical Medicine
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
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