Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Acta Brasiliensis (Online) |
Texto Completo: | http://revistas.ufcg.edu.br/ActaBra/index.php/actabra/article/view/43 |
Resumo: | Hallucinogenic plants are widely used in rituals and religious cults. Ayahuasca tea and wine black Jurema, both hallucinogenic beverages, present the alkaloid dimethyltryptamine (DMT) responsible for the hallucinogenic effect due to interaction with serotonergic receptors in the central nervous system (CNS). This research aimed to elucidate the mechanisms of action and the effects of DMT present on alumina drinks of the species Mimosa tenuiflora (jurema preta), Banisteriopsis caapi (jagube or cipó mariri) and Psychotria viridis (chacrona) on the CNS, elucidating the risks of their ingestion and information Brazilian legislation. The hallucinogenic effect occurs from the interaction of serotonergic receptors with DMT, this structurally similar to serotonin, which interferes with psychic functions, resulting in changes in dimensions, acoustic and optical illusions, mood alterations, distortion in the perception of time and Space, depersonalization, mydriasis, and hyperthermia. Currently there is free access to these substances and the diffusion of its use is expanding in Brazil due to its relationship with religious and cultural aspects. Thus, it is important to know the factors that encompass the use of these substances, since several alterations and complications can arise from the use, since the hallucinogenic effects come from interferences in physiological functions. |
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Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System Dimetiltriptamina: alcalóide alucinógeno e seus efeitos no Sistema Nervoso CentralHallucinogenic plants are widely used in rituals and religious cults. Ayahuasca tea and wine black Jurema, both hallucinogenic beverages, present the alkaloid dimethyltryptamine (DMT) responsible for the hallucinogenic effect due to interaction with serotonergic receptors in the central nervous system (CNS). This research aimed to elucidate the mechanisms of action and the effects of DMT present on alumina drinks of the species Mimosa tenuiflora (jurema preta), Banisteriopsis caapi (jagube or cipó mariri) and Psychotria viridis (chacrona) on the CNS, elucidating the risks of their ingestion and information Brazilian legislation. The hallucinogenic effect occurs from the interaction of serotonergic receptors with DMT, this structurally similar to serotonin, which interferes with psychic functions, resulting in changes in dimensions, acoustic and optical illusions, mood alterations, distortion in the perception of time and Space, depersonalization, mydriasis, and hyperthermia. Currently there is free access to these substances and the diffusion of its use is expanding in Brazil due to its relationship with religious and cultural aspects. Thus, it is important to know the factors that encompass the use of these substances, since several alterations and complications can arise from the use, since the hallucinogenic effects come from interferences in physiological functions.Plantas alucinógenas são bastante utilizadas em rituais e cultos religiosos. O chá de Ayahuasca e o vinho da Jurema preta, bebidas alucinógenas, apresentam o alcalóide dimetiltriptamina (DMT), responsável pelo efeito alucinógeno devido a interação com receptores serotoninérgicos no sistema nervoso central (SNC). O objetivo da pesquisa foi esclarecer os mecanismos de ação e os efeitos da DMT presente em bebidas alúcinógenas das espécies Mimosa tenuiflora (jurema preta), Banisteriopsis caapi (jagube ou cipó mariri) e Psychotria viridis (chacrona) sobre o SNC, elucidando os riscos da sua ingestão e informações sobre a legislação brasileira. O efeito alucinógeno ocorre a partir da interação dos receptores serotoninérgicos com DMT, esse estruturalmente semelhante a serotonina, o que interfere nas funções psíquicas, proporcionando modificações de dimensões, ilusões acústicas e ópticas, alterações no humor, distorção na percepção do tempo e espaço, despersonalização, midríase e hipertermia. Atualmente existe um acesso a essas substâncias e a difusão do seu uso está em expansão no Brasil, devido a relação com aspectos religiosos e culturais. Dessa forma, é importante conhecer os fatores que englobam o uso dessas substâncias, pois diversas alterações e complicações podem surgir a partir do uso, já que os efeitos alucinógenos provêm de interferências em funções fisiológicas.Universidade Federal de Campina Grande - UFCG2018-01-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://revistas.ufcg.edu.br/ActaBra/index.php/actabra/article/view/4310.22571/2526-433843Acta Brasiliensis; Vol 2 No 1 (2018): Acta Brasiliensis; 28-33Acta Brasiliensis; Vol 2 No 1 (2018): Acta Brasiliensis; 28-33Acta Brasiliensis; Vol 2 No 1 (2018): Acta Brasiliensis; 28-332526-43382526-432Xreponame:Acta Brasiliensis (Online)instname:Universidade Federal de Campina Grande (UFCG)instacron:UFCGporhttp://revistas.ufcg.edu.br/ActaBra/index.php/actabra/article/view/43/35Copyright (c) 2017 Acta Brasiliensisinfo:eu-repo/semantics/openAccessAlmeida, Darliane FreireAssis, Thais Josy Castro FreireSilva, Ana Ligia Pereira2021-07-12T20:04:13Zoai:ActaBra.revistas.ufcg.edu.br:article/43Revistahttp://revistas.ufcg.edu.br/ActaBraPUBhttp://revistas.ufcg.edu.br/ActaBra/index.php/actabra/oaiactabrasiliensis@gmail.com || actabrasiliensis@gmail.com2526-432X2526-4338opendoar:2021-07-12T20:04:13Acta Brasiliensis (Online) - Universidade Federal de Campina Grande (UFCG)false |
dc.title.none.fl_str_mv |
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System Dimetiltriptamina: alcalóide alucinógeno e seus efeitos no Sistema Nervoso Central |
title |
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System |
spellingShingle |
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System Almeida, Darliane Freire |
title_short |
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System |
title_full |
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System |
title_fullStr |
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System |
title_full_unstemmed |
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System |
title_sort |
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System |
author |
Almeida, Darliane Freire |
author_facet |
Almeida, Darliane Freire Assis, Thais Josy Castro Freire Silva, Ana Ligia Pereira |
author_role |
author |
author2 |
Assis, Thais Josy Castro Freire Silva, Ana Ligia Pereira |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Almeida, Darliane Freire Assis, Thais Josy Castro Freire Silva, Ana Ligia Pereira |
description |
Hallucinogenic plants are widely used in rituals and religious cults. Ayahuasca tea and wine black Jurema, both hallucinogenic beverages, present the alkaloid dimethyltryptamine (DMT) responsible for the hallucinogenic effect due to interaction with serotonergic receptors in the central nervous system (CNS). This research aimed to elucidate the mechanisms of action and the effects of DMT present on alumina drinks of the species Mimosa tenuiflora (jurema preta), Banisteriopsis caapi (jagube or cipó mariri) and Psychotria viridis (chacrona) on the CNS, elucidating the risks of their ingestion and information Brazilian legislation. The hallucinogenic effect occurs from the interaction of serotonergic receptors with DMT, this structurally similar to serotonin, which interferes with psychic functions, resulting in changes in dimensions, acoustic and optical illusions, mood alterations, distortion in the perception of time and Space, depersonalization, mydriasis, and hyperthermia. Currently there is free access to these substances and the diffusion of its use is expanding in Brazil due to its relationship with religious and cultural aspects. Thus, it is important to know the factors that encompass the use of these substances, since several alterations and complications can arise from the use, since the hallucinogenic effects come from interferences in physiological functions. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-20 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://revistas.ufcg.edu.br/ActaBra/index.php/actabra/article/view/43 10.22571/2526-433843 |
url |
http://revistas.ufcg.edu.br/ActaBra/index.php/actabra/article/view/43 |
identifier_str_mv |
10.22571/2526-433843 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
http://revistas.ufcg.edu.br/ActaBra/index.php/actabra/article/view/43/35 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Acta Brasiliensis info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Acta Brasiliensis |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Campina Grande - UFCG |
publisher.none.fl_str_mv |
Universidade Federal de Campina Grande - UFCG |
dc.source.none.fl_str_mv |
Acta Brasiliensis; Vol 2 No 1 (2018): Acta Brasiliensis; 28-33 Acta Brasiliensis; Vol 2 No 1 (2018): Acta Brasiliensis; 28-33 Acta Brasiliensis; Vol 2 No 1 (2018): Acta Brasiliensis; 28-33 2526-4338 2526-432X reponame:Acta Brasiliensis (Online) instname:Universidade Federal de Campina Grande (UFCG) instacron:UFCG |
instname_str |
Universidade Federal de Campina Grande (UFCG) |
instacron_str |
UFCG |
institution |
UFCG |
reponame_str |
Acta Brasiliensis (Online) |
collection |
Acta Brasiliensis (Online) |
repository.name.fl_str_mv |
Acta Brasiliensis (Online) - Universidade Federal de Campina Grande (UFCG) |
repository.mail.fl_str_mv |
actabrasiliensis@gmail.com || actabrasiliensis@gmail.com |
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1792204524533841920 |