Aspectos da infecção pelo helicobacter pylori nos resultados da cirurgia bariátrica

• Autor(a) principal: Silva, Fernanda Araújo Faber da
• Data de Publicação: 2015
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da Universidade Federal do Espírito Santo (riUfes)
• Texto Completo: http://repositorio.ufes.br/handle/10/5294
• topic: Obesity; Postoperative; Helicobacter pylori; Pós-operatório; Medicina; Obesidade; Operações cirúrgicas; 61

BACKGROUND: Obesity is a multifactorial disease highly prevalent, increasing incidence and spread throughout the world. It is an independent risk factor for numerous comorbidities such as type 2 diabetes mellitus, hypertension, dyslipidemia, metabolic syndrome, hepatic steatosis, gastroesophageal reflux disease, cholelithiasis, osteoarthritis, sleep apnea, among outras. O role of gastric infection H. pylori in obesity still generates much discussion. Helicobacter pylori (H. pylori) is a gram-negative bacterium that is associated with 75% of gastric carcinomas. Studies are needed to better understand the biology of H. pylori characteristics in order to develop strategies to deal with Helicobacter pylori infection, especially in postoperative patients of gastric bypass surgery Roux-Y, as it is bariatric surgery "Gold Standard" and his technique is left excluded stomach without conventional endoscopic access being home to many complications, especially gastric adenocarcinoma. It is known that patients infected with H. pylori, about 1-3% will develop cancer. OBJECTIVE: To evaluate aspects of H. pylori infection in the postoperative results of two surgical techniques for morbid obesity. METHODS AND RESULTS: A prospective clinical study evaluated the incidence of H. pylori in patients undergoing bariatric surgery, analyzing the two surgical techniques and comparing them. It was observed that the prevalence of H. pylori preoperative for the first year after surgery (p <005), remained sustained by the fifth year. There was no interference with the surgical technique. And in the morbidly obese, leukocytosis is related to H. pylori infection (p <0006). As for H. pylori infection can be observed that in the Vertical Gastrectomy group (GVA) of 1 year postoperatively for the 5th year there was an increase of anemia and infection by H. pylori, contrary occurred with the Gastric bypass technique Roux-Y (DGA). CONCLUSION: reducing the prevalence of Helicobacter pylori after bariatric surgery. Leukocytosis can relate to H. pylori infection. Infection with H. pylori does not prejudice the outcome of the surgery and can contribute to anemia in the postoperative period in patients undergoing bariatric surgery.