Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tede/10528 |
Resumo: | Obesity is a multifactorial disease that develops from an imbalance in the energy balance (EB). The lesion in the arcuate nucleus of the hypothalamus in rodents causes an imbalance in EB, biochemical and hormonal resulting in excess body fat storage in the body. The concentrated liquid extract of the residue of the fruit of the jabuticaba - Myrciaria cauliflora (ECJ) has become promising in the prevention/ treatment of chronic diseases, such as obesity, due to its bioactive compounds and antioxidant properties. The purpose of this work was to analyze the effects of ECJ (3%) on body mass, blood pressure, hematological and biochemical parameters in obese rats with monosodium glutamate (MSG). In the first days of life, the rats received subcutaneous injections in the posterior cervical region of MSG (4 mg/g) and control rats injected with isotonic saline (0.9%). After the weaning period (21 days), the animals were distributed in 4 experimental groups, treated or not for 60 days with the ECJ (3%) by gavage, group 1: control (CT); group 2: control treated with the extract (CT+E); group 3: monosodium glutamate (MSG); group 4: monosodium glutamate treated with the extract (MSG+E). In our study, rats that received injections of MSG with or without ECJ (3%) had: lower body weight gain and nasal/anal length, higher Lee index, and fat weight: retroperitoneal, inguinal and epididymal, lower cardiac index, lower liver and kidney weight, and lymphocytopenia. The rats that received only MSG showed an increase in mean blood pressure (MAP), increased levels of triglycerides (TG), and very-low-density lipoprotein (VLDL), leukopenia, the relative increase in monocytes, eosinophils and basophils. The MSG+E group demonstrated values of MAP, TG, VLDL, and leukocytes similar to those of animals CT+E and a lower level of low-density lipoprotein (LDL). There were no significant histological differences in cardiac tissue, total cholesterol, high-density lipoprotein, and in levels of tumor necrosis factor-alpha, interleukin 6, interleukin 4 and interleukin 10, in animals. From this, we concluded that the MSG was effective in inducing the obesity model and that the treatment with ECJ (3%) for 60 days demonstrated a beneficial protective action through PAM, TG, VLDL, and LDL altered by obesity. |
id |
UFG-2_1a212aec9eac816d1238cc1ed255739c |
---|---|
oai_identifier_str |
oai:repositorio.bc.ufg.br:tede/10528 |
network_acronym_str |
UFG-2 |
network_name_str |
Repositório Institucional da UFG |
repository_id_str |
|
spelling |
Oliveira , André Henrique Freiriahttp://lattes.cnpq.br/0152151142555605Blanch, Graziela Torreshttp://lattes.cnpq.br/8106735874828106Oliveira , André Henrique FreiriaRosa, Daniel AlvesFajemiroye, James Oluwagbamigbehttp://lattes.cnpq.br/8202836647237491Teófilo , Monatha Nayara Guimarães T2020-09-02T15:24:26Z2020-09-02T15:24:26Z2020-02-13TEÓFILO , Monatha Nayara Guimarães. Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico. 2020. 36 f. Dissertação (Mestrado em Ciências Fisiológicas) - Universidade Federal de Goiás, Goiânia, 2020.http://repositorio.bc.ufg.br/tede/handle/tede/10528Obesity is a multifactorial disease that develops from an imbalance in the energy balance (EB). The lesion in the arcuate nucleus of the hypothalamus in rodents causes an imbalance in EB, biochemical and hormonal resulting in excess body fat storage in the body. The concentrated liquid extract of the residue of the fruit of the jabuticaba - Myrciaria cauliflora (ECJ) has become promising in the prevention/ treatment of chronic diseases, such as obesity, due to its bioactive compounds and antioxidant properties. The purpose of this work was to analyze the effects of ECJ (3%) on body mass, blood pressure, hematological and biochemical parameters in obese rats with monosodium glutamate (MSG). In the first days of life, the rats received subcutaneous injections in the posterior cervical region of MSG (4 mg/g) and control rats injected with isotonic saline (0.9%). After the weaning period (21 days), the animals were distributed in 4 experimental groups, treated or not for 60 days with the ECJ (3%) by gavage, group 1: control (CT); group 2: control treated with the extract (CT+E); group 3: monosodium glutamate (MSG); group 4: monosodium glutamate treated with the extract (MSG+E). In our study, rats that received injections of MSG with or without ECJ (3%) had: lower body weight gain and nasal/anal length, higher Lee index, and fat weight: retroperitoneal, inguinal and epididymal, lower cardiac index, lower liver and kidney weight, and lymphocytopenia. The rats that received only MSG showed an increase in mean blood pressure (MAP), increased levels of triglycerides (TG), and very-low-density lipoprotein (VLDL), leukopenia, the relative increase in monocytes, eosinophils and basophils. The MSG+E group demonstrated values of MAP, TG, VLDL, and leukocytes similar to those of animals CT+E and a lower level of low-density lipoprotein (LDL). There were no significant histological differences in cardiac tissue, total cholesterol, high-density lipoprotein, and in levels of tumor necrosis factor-alpha, interleukin 6, interleukin 4 and interleukin 10, in animals. From this, we concluded that the MSG was effective in inducing the obesity model and that the treatment with ECJ (3%) for 60 days demonstrated a beneficial protective action through PAM, TG, VLDL, and LDL altered by obesity.A obesidade é uma doença multifatorial que se desenvolve a partir do desequilíbrio no balanço energético (BE). A lesão no núcleo arqueado do hipotálamo em roedores promove desequilíbrio no BE, bioquímico e hormonal resultando no excesso de armazenamento de gordura corporal no organismo. O extrato liquido concentrado do resíduo do fruto da jabuticaba – Myrciaria cauliflora (ECJ) tem se tornado promissor na prevenção/tratamento de doenças crônicas, como a obesidade, por apresenta compostos bioativos e propriedades antioxidantes. O propósito deste trabalho foi de analisar os efeitos do ECJ (3%) sobre a massa corporal, pressão arterial, parâmetros hematológicos e bioquímicos em ratos obesos por glutamato monossódico (MSG). Nos primeiros dias de vida, os ratos receberam injeções subcutâneas na região cervical posterior de MSG (4 mg/g) e ratos controle injeções de salina isotônica (0,9%). Após o período de desmame (21 dias), os animais foram distribuídos em 4 grupos experimentais, tratados ou não por 60 dias com o ECJ (3%) por gavagem, grupo 1: controle (CT); grupo 2: controle tratado com o extrato (CT+E); grupo 3: glutamato monossódico (MSG); grupo 4: glutamato monossódico tratado com o extrato (MSG+E). Em nosso estudo os ratos que receberam injeções do MSG com ou sem o ECJ (3%) apresentaram: menor ganho de peso corporal e comprimento naso/anal, maior índice de Lee e peso das gorduras: retroperitoneal, inguinal e epididimal, menor índice cardíaco, menor peso do fígado e dos rins e linfocitopenia. Os ratos que receberam somente o MSG, apresentaram aumento da pressão arterial media (PAM), aumento dos níveis de triglicerídeos (TG) e lipoproteína de muito baixa densidade (VLDL), leucopenia, aumento relativo de monócitos, eosinófilos e basófilos. O grupo MSG+E demonstrou valores da PAM, dos TG,VLDL e leucócitos semelhantes dos animais CT+E e menor nível da lipoproteína de baixa densidade (LDL). Não foram observadas diferenças significativas histológicas no tecido cardíaco, no colesterol total, lipoproteína de alta densidade, e nos níveis de fator de necrose tumoral alfa, interleucina 6, interleucina 4 e interleucina 10, nos animais. A partir disto, concluímos que o MSG foi eficaz em induzir o modelo de obesidade e que o tratamento com o ECJ (3%) por 60 dias demostrou ação protetiva benéfica mediante a PAM,TG, VLDL e LDL alterados pela obesidade.Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2020-09-01T18:04:19Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação - Monatha Nayara Guimarães Teófilo - 2020.pdf: 1335737 bytes, checksum: f8a7feab4e35e513d0acdd40429cab9b (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2020-09-02T15:24:26Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação - Monatha Nayara Guimarães Teófilo - 2020.pdf: 1335737 bytes, checksum: f8a7feab4e35e513d0acdd40429cab9b (MD5)Made available in DSpace on 2020-09-02T15:24:26Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação - Monatha Nayara Guimarães Teófilo - 2020.pdf: 1335737 bytes, checksum: f8a7feab4e35e513d0acdd40429cab9b (MD5) Previous issue date: 2020-02-13Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciências Fisiológicas - Multicêntrico (ICB)UFGBrasilInstituto de Ciências Biológicas - ICB (RG)Attribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessExtratoJabuticabaObesidadeNúcleo arqueadoMetabolismoExtractObesityArcuate nucleusMetabolismCIENCIAS BIOLOGICAS::FISIOLOGIAEfeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódicoEffect of concentrated liquid extract obtained from agroindustrial residues of the fruits of Myrciaria cauliflora on cardiometabolic parameters of Wistar rats undergoing the monosodium glutamate-induced obesity modelinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis27500500500500241651reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.bc.ufg.br/tede/bitstreams/7c4b2b6c-7c5d-4adf-a697-d852c6b4398a/download8a4605be74aa9ea9d79846c1fba20a33MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8811http://repositorio.bc.ufg.br/tede/bitstreams/6ac434bc-e861-42f3-84f9-13e31a23cd76/downloade39d27027a6cc9cb039ad269a5db8e34MD52ORIGINALDissertação - Monatha Nayara Guimarães Teófilo - 2020.pdfDissertação - Monatha Nayara Guimarães Teófilo - 2020.pdfapplication/pdf1335737http://repositorio.bc.ufg.br/tede/bitstreams/a6328e39-9e4a-4734-9a89-1e26be7d5251/downloadf8a7feab4e35e513d0acdd40429cab9bMD53tede/105282020-09-02 12:24:26.548http://creativecommons.org/licenses/by-nc-nd/3.0/br/Attribution-NonCommercial-NoDerivs 3.0 Brazilopen.accessoai:repositorio.bc.ufg.br:tede/10528http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2020-09-02T15:24:26Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)falseTk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo= |
dc.title.pt_BR.fl_str_mv |
Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico |
dc.title.alternative.eng.fl_str_mv |
Effect of concentrated liquid extract obtained from agroindustrial residues of the fruits of Myrciaria cauliflora on cardiometabolic parameters of Wistar rats undergoing the monosodium glutamate-induced obesity model |
title |
Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico |
spellingShingle |
Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico Teófilo , Monatha Nayara Guimarães T Extrato Jabuticaba Obesidade Núcleo arqueado Metabolismo Extract Obesity Arcuate nucleus Metabolism CIENCIAS BIOLOGICAS::FISIOLOGIA |
title_short |
Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico |
title_full |
Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico |
title_fullStr |
Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico |
title_full_unstemmed |
Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico |
title_sort |
Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico |
author |
Teófilo , Monatha Nayara Guimarães T |
author_facet |
Teófilo , Monatha Nayara Guimarães T |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Oliveira , André Henrique Freiria |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/0152151142555605 |
dc.contributor.advisor-co1.fl_str_mv |
Blanch, Graziela Torres |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/8106735874828106 |
dc.contributor.referee1.fl_str_mv |
Oliveira , André Henrique Freiria |
dc.contributor.referee2.fl_str_mv |
Rosa, Daniel Alves |
dc.contributor.referee3.fl_str_mv |
Fajemiroye, James Oluwagbamigbe |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/8202836647237491 |
dc.contributor.author.fl_str_mv |
Teófilo , Monatha Nayara Guimarães T |
contributor_str_mv |
Oliveira , André Henrique Freiria Blanch, Graziela Torres Oliveira , André Henrique Freiria Rosa, Daniel Alves Fajemiroye, James Oluwagbamigbe |
dc.subject.por.fl_str_mv |
Extrato Jabuticaba Obesidade Núcleo arqueado Metabolismo |
topic |
Extrato Jabuticaba Obesidade Núcleo arqueado Metabolismo Extract Obesity Arcuate nucleus Metabolism CIENCIAS BIOLOGICAS::FISIOLOGIA |
dc.subject.eng.fl_str_mv |
Extract Obesity Arcuate nucleus Metabolism |
dc.subject.cnpq.fl_str_mv |
CIENCIAS BIOLOGICAS::FISIOLOGIA |
description |
Obesity is a multifactorial disease that develops from an imbalance in the energy balance (EB). The lesion in the arcuate nucleus of the hypothalamus in rodents causes an imbalance in EB, biochemical and hormonal resulting in excess body fat storage in the body. The concentrated liquid extract of the residue of the fruit of the jabuticaba - Myrciaria cauliflora (ECJ) has become promising in the prevention/ treatment of chronic diseases, such as obesity, due to its bioactive compounds and antioxidant properties. The purpose of this work was to analyze the effects of ECJ (3%) on body mass, blood pressure, hematological and biochemical parameters in obese rats with monosodium glutamate (MSG). In the first days of life, the rats received subcutaneous injections in the posterior cervical region of MSG (4 mg/g) and control rats injected with isotonic saline (0.9%). After the weaning period (21 days), the animals were distributed in 4 experimental groups, treated or not for 60 days with the ECJ (3%) by gavage, group 1: control (CT); group 2: control treated with the extract (CT+E); group 3: monosodium glutamate (MSG); group 4: monosodium glutamate treated with the extract (MSG+E). In our study, rats that received injections of MSG with or without ECJ (3%) had: lower body weight gain and nasal/anal length, higher Lee index, and fat weight: retroperitoneal, inguinal and epididymal, lower cardiac index, lower liver and kidney weight, and lymphocytopenia. The rats that received only MSG showed an increase in mean blood pressure (MAP), increased levels of triglycerides (TG), and very-low-density lipoprotein (VLDL), leukopenia, the relative increase in monocytes, eosinophils and basophils. The MSG+E group demonstrated values of MAP, TG, VLDL, and leukocytes similar to those of animals CT+E and a lower level of low-density lipoprotein (LDL). There were no significant histological differences in cardiac tissue, total cholesterol, high-density lipoprotein, and in levels of tumor necrosis factor-alpha, interleukin 6, interleukin 4 and interleukin 10, in animals. From this, we concluded that the MSG was effective in inducing the obesity model and that the treatment with ECJ (3%) for 60 days demonstrated a beneficial protective action through PAM, TG, VLDL, and LDL altered by obesity. |
publishDate |
2020 |
dc.date.accessioned.fl_str_mv |
2020-09-02T15:24:26Z |
dc.date.available.fl_str_mv |
2020-09-02T15:24:26Z |
dc.date.issued.fl_str_mv |
2020-02-13 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
TEÓFILO , Monatha Nayara Guimarães. Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico. 2020. 36 f. Dissertação (Mestrado em Ciências Fisiológicas) - Universidade Federal de Goiás, Goiânia, 2020. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/10528 |
identifier_str_mv |
TEÓFILO , Monatha Nayara Guimarães. Efeito do extrato líquido concentrado obtido dos resíduos agroindustriais dos frutos de Myrciaria cauliflora sobre parâmetros cardiometabólicos de ratos Wistar submetidos ao modelo de obesidade induzida por glutamato monossódico. 2020. 36 f. Dissertação (Mestrado em Ciências Fisiológicas) - Universidade Federal de Goiás, Goiânia, 2020. |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/10528 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
27 |
dc.relation.confidence.fl_str_mv |
500 500 500 500 |
dc.relation.department.fl_str_mv |
24 |
dc.relation.cnpq.fl_str_mv |
165 |
dc.relation.sponsorship.fl_str_mv |
1 |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Programa de Pós-graduação em Ciências Fisiológicas - Multicêntrico (ICB) |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Instituto de Ciências Biológicas - ICB (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFG instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Repositório Institucional da UFG |
collection |
Repositório Institucional da UFG |
bitstream.url.fl_str_mv |
http://repositorio.bc.ufg.br/tede/bitstreams/7c4b2b6c-7c5d-4adf-a697-d852c6b4398a/download http://repositorio.bc.ufg.br/tede/bitstreams/6ac434bc-e861-42f3-84f9-13e31a23cd76/download http://repositorio.bc.ufg.br/tede/bitstreams/a6328e39-9e4a-4734-9a89-1e26be7d5251/download |
bitstream.checksum.fl_str_mv |
8a4605be74aa9ea9d79846c1fba20a33 e39d27027a6cc9cb039ad269a5db8e34 f8a7feab4e35e513d0acdd40429cab9b |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFG - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
tasesdissertacoes.bc@ufg.br |
_version_ |
1798044330377609216 |