Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados

Detalhes bibliográficos
Autor(a) principal: Saidah, Tárik Kassem
Data de Publicação: 2015
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFG
dARK ID: ark:/38995/00130000018n2
Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/5343
Resumo: Aims: To make a review article on ectopic pregnancy (EP) in high complexity fertilization, to define the epidemiological and reproductive profile of women carriers of EP, to evaluate the prevalence of EP after in vitro fertilization (IVF) and to verify if the transfer of frozen embryos reduces the rates of EP. METHODS: All fresh and frozen embryos transfers obtained through IVF via ICSI conducted between January 2007 and December 2014 were reviewed. Clinical pregnancies characterized by the visualization of an intrauterine gestational sac or ectopic pregnancy were included in the evaluation. Ectopic pregnancies were diagnosed by ultrasonography and / or laparoscopy. The prevalence of EP and the comparison of the rates between fresh and frozen embryos transfers were analyzed by logistic regression using the SPPS software version 15.0. Results: Of the 933 embryos obtained through IVF that resulted in clinical pregnancies, 19 cases of EP were found. The fertilization with fresh embryos resulted in 772 clinical pregnancies (group I), and 161 with frozen embryos (group II). The global prevalence of EP was 2.02%. When considered by group, group one had 16 EP that represented a rate of 2.1% and group two had a rate of 1.9%. There was a lower rate of ectopic pregnancy with frozen embryos in comparison to fresh embryos, although this did not demonstrate statistical significance (p=0.86)(OR=0.89, IC=0.258-3.11). CONCLUSIONS: The reproductive profile of patients that exhibit EP was of young female with young partner, good ovarian response and that had more than 3 embryos transferred. The prevalence of EP in this study was 2.02. It was observed that there was no significant difference in the occurrence of EP when both groups, frozen and fresh embryos, were compared.
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spelling Amaral, Waldemar Naves dohttp://lattes.cnpq.br/4092560599116579Amaral, Waldemar Naves doSousa, Juarez Antônio deViggiano, Marcello Bragahttp://lattes.cnpq.br/7930409410650712Saidah, Tárik Kassem2016-03-17T11:54:08Z2015-09-20SAIDAH, T. K. Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados. 2015. 61 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2015.http://repositorio.bc.ufg.br/tede/handle/tede/5343ark:/38995/00130000018n2Aims: To make a review article on ectopic pregnancy (EP) in high complexity fertilization, to define the epidemiological and reproductive profile of women carriers of EP, to evaluate the prevalence of EP after in vitro fertilization (IVF) and to verify if the transfer of frozen embryos reduces the rates of EP. METHODS: All fresh and frozen embryos transfers obtained through IVF via ICSI conducted between January 2007 and December 2014 were reviewed. Clinical pregnancies characterized by the visualization of an intrauterine gestational sac or ectopic pregnancy were included in the evaluation. Ectopic pregnancies were diagnosed by ultrasonography and / or laparoscopy. The prevalence of EP and the comparison of the rates between fresh and frozen embryos transfers were analyzed by logistic regression using the SPPS software version 15.0. Results: Of the 933 embryos obtained through IVF that resulted in clinical pregnancies, 19 cases of EP were found. The fertilization with fresh embryos resulted in 772 clinical pregnancies (group I), and 161 with frozen embryos (group II). The global prevalence of EP was 2.02%. When considered by group, group one had 16 EP that represented a rate of 2.1% and group two had a rate of 1.9%. There was a lower rate of ectopic pregnancy with frozen embryos in comparison to fresh embryos, although this did not demonstrate statistical significance (p=0.86)(OR=0.89, IC=0.258-3.11). CONCLUSIONS: The reproductive profile of patients that exhibit EP was of young female with young partner, good ovarian response and that had more than 3 embryos transferred. The prevalence of EP in this study was 2.02. It was observed that there was no significant difference in the occurrence of EP when both groups, frozen and fresh embryos, were compared.Objetivos: fazer um artigo de revisão sobre gestação ectópica (GE) em fertilização de alta complexidade, definir o perfil epidemiológico e reprodutivo das mulheres portadores de GE, avaliar a prevalência de GE pós-fertilização de alta complexidade e verificar se a transferência de embriões congelados reduz as taxas de GE. Métodos: foram revisadas todas as transferências de embriões frescos e congelados realizadas através de fertilização in vitro pela técnica de injeção intracitoplasmática de espermatozoides no período compreendido entre janeiro de 2007 a dezembro de 2014. Foram incluídas as gestações clínicas, sendo consideradas as gestações com visualização de saco gestacional intraútero e gestações ectópicas. As gestações ectópicas foram diagnosticadas por ultrassonografia e/ou laparoscopia. A prevalência de ectópica e a comparação das taxas entre os grupos de embriões frescos e congelados foram verificadas por meio da análise de regressão logística utilizando o programa Software SPSS versão 15.0. Resultados: foram analisadas 933 fertilizações in vitro que resultaram em gestações clínicas e verificou-se 19 casos de gestações ectópicas. As fertilizações com embriões frescos totalizaram 772 (grupo I) e com embriões congelados 161 (grupo 2). A prevalência de gestação ectópica foi de 2,02 %. No grupo I ocorreram 16 gestações ectópicas representando uma taxa de 2,1 % das fertilizações, no grupo 2 a taxa foi de 1,9 %. Uma menor taxa de gestação ectópica com embriões congelados foi verificada em comparação com embriões frescos, porém, não apresentou significância estatística (p=0,86) (OR= 0,89, IC 0,258 – 3,11). Conclusões: o perfil reprodutivo das pacientes que apresentaram GE foi de mulheres jovens com parceiros jovens, com boa resposta ovariana e que tiveram mais de três embriões transferidos. A prevalência de GE verificada no presente estudo foi de 2,02 %. Observou-se que não houve diferença significativa quanto à GE quando foram comparadas as transferências de embriões frescos com os congelados.Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2016-03-17T11:52:18Z No. of bitstreams: 2 Dissertação - Tárik Kassem Saidah - 2015.pdf: 2186450 bytes, checksum: ff29c97a86ff6cb315b6365052160a3f (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-03-17T11:54:08Z (GMT) No. of bitstreams: 2 Dissertação - Tárik Kassem Saidah - 2015.pdf: 2186450 bytes, checksum: ff29c97a86ff6cb315b6365052160a3f (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Made available in DSpace on 2016-03-17T11:54:08Z (GMT). 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dc.title.por.fl_str_mv Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados
dc.title.alternative.eng.fl_str_mv Ectopic pregnancy in IVF – analytical study with fresh and frozen embryos
title Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados
spellingShingle Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados
Saidah, Tárik Kassem
Gestação ectópica
FIV
ICSI
Prevalência
Transferência de embrião
CIENCIAS DA SAUDE
title_short Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados
title_full Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados
title_fullStr Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados
title_full_unstemmed Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados
title_sort Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados
author Saidah, Tárik Kassem
author_facet Saidah, Tárik Kassem
author_role author
dc.contributor.advisor1.fl_str_mv Amaral, Waldemar Naves do
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/4092560599116579
dc.contributor.referee1.fl_str_mv Amaral, Waldemar Naves do
dc.contributor.referee2.fl_str_mv Sousa, Juarez Antônio de
dc.contributor.referee3.fl_str_mv Viggiano, Marcello Braga
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/7930409410650712
dc.contributor.author.fl_str_mv Saidah, Tárik Kassem
contributor_str_mv Amaral, Waldemar Naves do
Amaral, Waldemar Naves do
Sousa, Juarez Antônio de
Viggiano, Marcello Braga
dc.subject.por.fl_str_mv Gestação ectópica
FIV
ICSI
Prevalência
Transferência de embrião
topic Gestação ectópica
FIV
ICSI
Prevalência
Transferência de embrião
CIENCIAS DA SAUDE
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE
description Aims: To make a review article on ectopic pregnancy (EP) in high complexity fertilization, to define the epidemiological and reproductive profile of women carriers of EP, to evaluate the prevalence of EP after in vitro fertilization (IVF) and to verify if the transfer of frozen embryos reduces the rates of EP. METHODS: All fresh and frozen embryos transfers obtained through IVF via ICSI conducted between January 2007 and December 2014 were reviewed. Clinical pregnancies characterized by the visualization of an intrauterine gestational sac or ectopic pregnancy were included in the evaluation. Ectopic pregnancies were diagnosed by ultrasonography and / or laparoscopy. The prevalence of EP and the comparison of the rates between fresh and frozen embryos transfers were analyzed by logistic regression using the SPPS software version 15.0. Results: Of the 933 embryos obtained through IVF that resulted in clinical pregnancies, 19 cases of EP were found. The fertilization with fresh embryos resulted in 772 clinical pregnancies (group I), and 161 with frozen embryos (group II). The global prevalence of EP was 2.02%. When considered by group, group one had 16 EP that represented a rate of 2.1% and group two had a rate of 1.9%. There was a lower rate of ectopic pregnancy with frozen embryos in comparison to fresh embryos, although this did not demonstrate statistical significance (p=0.86)(OR=0.89, IC=0.258-3.11). CONCLUSIONS: The reproductive profile of patients that exhibit EP was of young female with young partner, good ovarian response and that had more than 3 embryos transferred. The prevalence of EP in this study was 2.02. It was observed that there was no significant difference in the occurrence of EP when both groups, frozen and fresh embryos, were compared.
publishDate 2015
dc.date.issued.fl_str_mv 2015-09-20
dc.date.accessioned.fl_str_mv 2016-03-17T11:54:08Z
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dc.identifier.citation.fl_str_mv SAIDAH, T. K. Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados. 2015. 61 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2015.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/5343
dc.identifier.dark.fl_str_mv ark:/38995/00130000018n2
identifier_str_mv SAIDAH, T. K. Gestação ectópica em fertilização in vitro – estudo analítico com embriões frescos e congelados. 2015. 61 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2015.
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