Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tede/11144 |
Resumo: | Introduction: Rigor in the selection process of donors led to a decrease in the number of individuals who meet the criteria of clinical and serological suitability for blood donation. In contrast, advances in medicine and the life expectancy of the population have led to an increase in the consumption of blood components. These factors created a challenge for hemotherapy services to guarantee the fulfillment of transfusion demand, combining the availability of blood products in their quality. This scenario led to the search for strategies to attract donors, such as the introduction of incentives to increase the number of donations. Objectives: Conduct a temporal analysis of the profile of blood donations performed in a public blood bank. Materials and methods: Retrospective study of donations between 2010-2016. Part of the analysis was stratified into three periods: before, during and after changing the criteria of an incentive program. Multinomial and multivariate logistic regression was used to verify the association between the explanatory variables and the positive serologies. Trends was evaluated by Prais Winsten's Regression. The Kruskal Wallis test was used to evaluate the seasonality. Results: 149,983 donations (1.08% of the local population) were performed, with a reduction of 29% (p <0.05). 49% of the donations were of the voluntary modality, 30% of campaign, 18% of replacement and 3% of other types of donation. The campaign donations had a 5.67% increase during the first study period (p <0.05), a decrease of 0.85% in the 2nd period (p> 0.05) and 6.65% in the 3rd period (p> 0.05) resulting in a total decrease of 5.02% (p <0.05). The transfusional transmissible infections rate was 3.71%, with a stationary tendency and the chance of donors having a serological disability was lower (OR = 0.8628; CI: 0.8126 - 0.9161; p < 0.0001). Seroprevalences for HBV, syphilis, HCV, HIV, Chagas disease and HTLV were 1.63%, 0.87%, 0.46%, 0.21%, 0.21% and 0.09%, espectively. The prevalence of HBV decreased (b = -0.021, p <0.001), while syphilis increased (b = 0.112; p = 0.001). Conclusion: The amount of blood donation is decreasing, which may be related to the decrease in campaign donations. |
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Alcântara, Keila Correia dehttp://lattes.cnpq.br/3089303305362001Alcântara, Keila Correia deSantos, Thalyta Renata de AraújoLeles, Renan Nuneshttp://lattes.cnpq.br/2962342135474550Pessoni, Lívia Lara2021-03-05T15:16:31Z2021-03-05T15:16:31Z2018-03-06PESSONI, L. L. Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil. 2018. 83 f. Dissertação (Mestrado em Assistência e Avaliação em Saúde) - Universidade Federal de Goiás, Goiânia, 2018.http://repositorio.bc.ufg.br/tede/handle/tede/11144Introduction: Rigor in the selection process of donors led to a decrease in the number of individuals who meet the criteria of clinical and serological suitability for blood donation. In contrast, advances in medicine and the life expectancy of the population have led to an increase in the consumption of blood components. These factors created a challenge for hemotherapy services to guarantee the fulfillment of transfusion demand, combining the availability of blood products in their quality. This scenario led to the search for strategies to attract donors, such as the introduction of incentives to increase the number of donations. Objectives: Conduct a temporal analysis of the profile of blood donations performed in a public blood bank. Materials and methods: Retrospective study of donations between 2010-2016. Part of the analysis was stratified into three periods: before, during and after changing the criteria of an incentive program. Multinomial and multivariate logistic regression was used to verify the association between the explanatory variables and the positive serologies. Trends was evaluated by Prais Winsten's Regression. The Kruskal Wallis test was used to evaluate the seasonality. Results: 149,983 donations (1.08% of the local population) were performed, with a reduction of 29% (p <0.05). 49% of the donations were of the voluntary modality, 30% of campaign, 18% of replacement and 3% of other types of donation. The campaign donations had a 5.67% increase during the first study period (p <0.05), a decrease of 0.85% in the 2nd period (p> 0.05) and 6.65% in the 3rd period (p> 0.05) resulting in a total decrease of 5.02% (p <0.05). The transfusional transmissible infections rate was 3.71%, with a stationary tendency and the chance of donors having a serological disability was lower (OR = 0.8628; CI: 0.8126 - 0.9161; p < 0.0001). Seroprevalences for HBV, syphilis, HCV, HIV, Chagas disease and HTLV were 1.63%, 0.87%, 0.46%, 0.21%, 0.21% and 0.09%, espectively. The prevalence of HBV decreased (b = -0.021, p <0.001), while syphilis increased (b = 0.112; p = 0.001). Conclusion: The amount of blood donation is decreasing, which may be related to the decrease in campaign donations.Introdução: O rigor no processo de seleção de doadores levou a um decréscimo no número de indivíduos que preenchem os critérios de aptidão clínica e sorológica para doação de sangue. Em contrapartida os avanços na medicina e na expectativa de vida da população levaram ao aumento do consumo de hemocomponentes. Esses fatores geraram um desafio para os serviços de hemoterapia para garantir o atendimento da demanda transfusional, aliando disponibilidade dos produtos sanguíneos à sua qualidade. Esse cenário, ocasionou a busca de estratégias de captação de doadores como a introdução de incentivos para aumentar o número de doações. Objetivos: Realizar uma análise temporal do perfil das doações de sangue realizadas em um banco de sangue público. Materiais e métodos: Estudo retrospectivo das doações realizadas entre 2010-2016. Parte da análise foi estratificada em três períodos: antes (1º período), durante (2º período) e após alteração nos critérios de um programa de incentivo (3º período). Foi utilizada regressão logística multinomial e multivariada para verificar a associação entre as variáveis explicativas e as sorologias positivas. A tendência foi avaliada pela Regressão de Prais Winsten. O teste de Kruskal Wallis foi usado para avaliar a sazonalidade. Resultados: Foram realizadas 149.983 doações (1,08% da população local) com redução de 29% (p<0,05) nos sete anos analisados. 49%das doações foram da modalidade voluntária, 30% de campanha, 18% de reposição e 3% de outros tipos de doação. As doações de campanha tiveram um incremento de 5,67% durante o 1º período de estudo (p<0,05), decréscimo de -0,85% no 2º período (p>0,05) e -6,65% no 3º período (p>0,05) resultando em um decréscimo total de -5,02% (p<0,05). A taxa de inaptidão sorológica foi de 3,71%, com tendência estacionária no período analisado, e a chance de doadores de campanha apresentarem inaptidão sorológica foi menor (OR = 0,8628; IC: 0,8126 - 0,9161; p < 0,0001) que as demais modalidades de doação. As soroprevalências para HBV, sífilis, HCV, HIV, doença de chagas e HTLV foram 1,63%, 0,87%, 0,46%, 0,21%, 0,21% e 0,09%, respectivamente. No período analisado a prevalência de HBV dimimuiu (b = -0.021; p< 0.001), enquanto a de sífilis aumentou (b = 0,112; p = 0,001). Conclusão: A quantidade de doações de sangue está dimimuindo, o que pode estar relacionado com a diminuição das doações de campanha, a qual os doadores apresentam as menores taxas/chances de apresentarem inaptidão sorológica, quando comparados com as outras modalidades de doação.Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2021-03-05T15:00:14Z No. of bitstreams: 2 license_rdf: 805 bytes, checksum: 4460e5956bc1d1639be9ae6146a50347 (MD5) Dissertação - Lívia Lara Pessoni - 2018.pdf: 2308179 bytes, checksum: c5b6fa1c7cb19716a8072ddc57ee207a (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2021-03-05T15:16:31Z (GMT) No. of bitstreams: 2 license_rdf: 805 bytes, checksum: 4460e5956bc1d1639be9ae6146a50347 (MD5) Dissertação - Lívia Lara Pessoni - 2018.pdf: 2308179 bytes, checksum: c5b6fa1c7cb19716a8072ddc57ee207a (MD5)Made available in DSpace on 2021-03-05T15:16:31Z (GMT). No. of bitstreams: 2 license_rdf: 805 bytes, checksum: 4460e5956bc1d1639be9ae6146a50347 (MD5) Dissertação - Lívia Lara Pessoni - 2018.pdf: 2308179 bytes, checksum: c5b6fa1c7cb19716a8072ddc57ee207a (MD5) Previous issue date: 2018-03-06OutroporUniversidade Federal de GoiásPrograma de Pós-graduação em Assistência e Avaliação em Saúde (FF)UFGBrasilFaculdade de Farmácia - FF (RG)Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessDoação de sangueCaptação de doadoresInaptidão sorológicaBlood donationDonor recruitmentSerological inabilityCIENCIAS DA SAUDE::FARMACIA::ANALISE TOXICOLOGICAAnálise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no BrasilTemporal analysis of the donation profile and the serological inability rate of a public blood bank in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis10500500500500225135reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.bc.ufg.br/tede/bitstreams/ac8a2a7d-8815-4210-841b-41a5597fe60d/download8a4605be74aa9ea9d79846c1fba20a33MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805http://repositorio.bc.ufg.br/tede/bitstreams/639f100a-e751-4e7c-af1b-075d4640c9be/download4460e5956bc1d1639be9ae6146a50347MD52ORIGINALDissertação - Lívia Lara Pessoni - 2018.pdfDissertação - Lívia Lara Pessoni - 2018.pdfapplication/pdf2308179http://repositorio.bc.ufg.br/tede/bitstreams/15e27d99-5c40-45ad-9e28-c38388ba25f5/downloadc5b6fa1c7cb19716a8072ddc57ee207aMD53tede/111442021-03-05 12:16:32.332http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internationalopen.accessoai:repositorio.bc.ufg.br:tede/11144http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2021-03-05T15:16:32Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)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 |
dc.title.pt_BR.fl_str_mv |
Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil |
dc.title.alternative.eng.fl_str_mv |
Temporal analysis of the donation profile and the serological inability rate of a public blood bank in Brazil |
title |
Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil |
spellingShingle |
Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil Pessoni, Lívia Lara Doação de sangue Captação de doadores Inaptidão sorológica Blood donation Donor recruitment Serological inability CIENCIAS DA SAUDE::FARMACIA::ANALISE TOXICOLOGICA |
title_short |
Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil |
title_full |
Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil |
title_fullStr |
Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil |
title_full_unstemmed |
Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil |
title_sort |
Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil |
author |
Pessoni, Lívia Lara |
author_facet |
Pessoni, Lívia Lara |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Alcântara, Keila Correia de |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/3089303305362001 |
dc.contributor.referee1.fl_str_mv |
Alcântara, Keila Correia de |
dc.contributor.referee2.fl_str_mv |
Santos, Thalyta Renata de Araújo |
dc.contributor.referee3.fl_str_mv |
Leles, Renan Nunes |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/2962342135474550 |
dc.contributor.author.fl_str_mv |
Pessoni, Lívia Lara |
contributor_str_mv |
Alcântara, Keila Correia de Alcântara, Keila Correia de Santos, Thalyta Renata de Araújo Leles, Renan Nunes |
dc.subject.por.fl_str_mv |
Doação de sangue Captação de doadores Inaptidão sorológica |
topic |
Doação de sangue Captação de doadores Inaptidão sorológica Blood donation Donor recruitment Serological inability CIENCIAS DA SAUDE::FARMACIA::ANALISE TOXICOLOGICA |
dc.subject.eng.fl_str_mv |
Blood donation Donor recruitment Serological inability |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::FARMACIA::ANALISE TOXICOLOGICA |
description |
Introduction: Rigor in the selection process of donors led to a decrease in the number of individuals who meet the criteria of clinical and serological suitability for blood donation. In contrast, advances in medicine and the life expectancy of the population have led to an increase in the consumption of blood components. These factors created a challenge for hemotherapy services to guarantee the fulfillment of transfusion demand, combining the availability of blood products in their quality. This scenario led to the search for strategies to attract donors, such as the introduction of incentives to increase the number of donations. Objectives: Conduct a temporal analysis of the profile of blood donations performed in a public blood bank. Materials and methods: Retrospective study of donations between 2010-2016. Part of the analysis was stratified into three periods: before, during and after changing the criteria of an incentive program. Multinomial and multivariate logistic regression was used to verify the association between the explanatory variables and the positive serologies. Trends was evaluated by Prais Winsten's Regression. The Kruskal Wallis test was used to evaluate the seasonality. Results: 149,983 donations (1.08% of the local population) were performed, with a reduction of 29% (p <0.05). 49% of the donations were of the voluntary modality, 30% of campaign, 18% of replacement and 3% of other types of donation. The campaign donations had a 5.67% increase during the first study period (p <0.05), a decrease of 0.85% in the 2nd period (p> 0.05) and 6.65% in the 3rd period (p> 0.05) resulting in a total decrease of 5.02% (p <0.05). The transfusional transmissible infections rate was 3.71%, with a stationary tendency and the chance of donors having a serological disability was lower (OR = 0.8628; CI: 0.8126 - 0.9161; p < 0.0001). Seroprevalences for HBV, syphilis, HCV, HIV, Chagas disease and HTLV were 1.63%, 0.87%, 0.46%, 0.21%, 0.21% and 0.09%, espectively. The prevalence of HBV decreased (b = -0.021, p <0.001), while syphilis increased (b = 0.112; p = 0.001). Conclusion: The amount of blood donation is decreasing, which may be related to the decrease in campaign donations. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-03-06 |
dc.date.accessioned.fl_str_mv |
2021-03-05T15:16:31Z |
dc.date.available.fl_str_mv |
2021-03-05T15:16:31Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
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masterThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
PESSONI, L. L. Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil. 2018. 83 f. Dissertação (Mestrado em Assistência e Avaliação em Saúde) - Universidade Federal de Goiás, Goiânia, 2018. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/11144 |
identifier_str_mv |
PESSONI, L. L. Análise temporal do perfil de doações e da taxa de inaptidão sorológica de um banco de sangue público no Brasil. 2018. 83 f. Dissertação (Mestrado em Assistência e Avaliação em Saúde) - Universidade Federal de Goiás, Goiânia, 2018. |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/11144 |
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por |
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Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
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Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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Universidade Federal de Goiás |
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Programa de Pós-graduação em Assistência e Avaliação em Saúde (FF) |
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UFG |
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Brasil |
dc.publisher.department.fl_str_mv |
Faculdade de Farmácia - FF (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
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