Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tede/7430 |
Resumo: | Homeless people are at high risk for parental and sexual infections, such as hepatitis C virus (HCV) infection. This study aimed to investigate the epidemiological profile of the infection caused by the hepatitis C virus in homeless people housed in Goiânia, Goiás. This is an observational, cross-sectional and analytical investigation. Between August 2014 and July 2015, 353 homeless people hosted in the only public institution of the state of Goiás were interviewed about sociodemographic characteristics, knowledge and risk factors for hepatitis C, and subsequently tested for the detection of the marker HCV by immunochromatographic test (rapid test) and ELISA. In addition, monitoring of individuals reagentes for HCV was conducted through the information systems of the Unified Health System. The Poisson regression analysis was used to verify the risk factors associated with exposure to HCV with robust variance for the calculation of prevalence ratio (PR). The investigated were mostly male (81.3%), aged between 18 and 45 years (73.62%), singles (59.8%), with no income (35.7), with 5 to 9 years of study (53.3%) and self-reported brown color (61.1%). The study evidenced a knowledge deficit of the homeless people investigated in relation to the HCV transmission. The rapid test used in this study had a high index of agreement with the ELISA, whose sensitivity and specificity was 91.7% and 99.7%, respectively. The overall prevalence of HCV in the homeless people housed was 3.4% (95% CI: 1.9-5.8). It was noted that age (RP: 1.05, 95% CI: 1.02-1.09), be natural from the Southeast region (RP: 2.27, 95% CI: 1.03-5.02), overnight experience in the street (RP: 2.78, 95% CI: 1.11-6.91) and the use of injectable drugs (UID) (PR: 16.59, 95% CI: 4.23-65.09) were statistically associated with HCV infection. Of the 12 housed positive for HCV, only two sought treatment, but there was no adhesion, and another two others evolved to death as a consequence of hepatic cirrhosis due to hepatitis C. The results of the study ratify the extreme condition of homeless people and the increased risk of acquiring and disseminating the hepatitis C virus. Therefore, to prevent and / or minimize risk behaviors for HCV, it is necessary behavioral and structural interventions with combined strategies, such as health education and counseling, permanent education, provision of rapid testing and barrier methods (condom), multidisciplinary treatment, strengthening the strategy of damage reduction, evaluation of policies for homeless people, solidifying the social care equipment provided to this group, such as shelters and access to the services that comprise the health care network. |
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Matos, Marcos André dehttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4771225T1Teles, Sheila AraújoMartins, Regina Maria BringelCaetano, Karlla Antonieta AmorimMatos, Márcia Alves Dias dehttps://wwws.cnpq.br/cvlattesweb/PKG_MENU.menu?f_cod= 751A19DE30F9970674B4F2C99449CD94Souza, Jéssyca Pereira e2017-06-08T12:48:33Z2017-04-25SOUZA, Jéssyca Pereira e. Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados. 2017. 110 f. Dissertação (Mestrado em Enfermagem) - Universidade Federal de Goiás, Goiânia, 2017.http://repositorio.bc.ufg.br/tede/handle/tede/7430Homeless people are at high risk for parental and sexual infections, such as hepatitis C virus (HCV) infection. This study aimed to investigate the epidemiological profile of the infection caused by the hepatitis C virus in homeless people housed in Goiânia, Goiás. This is an observational, cross-sectional and analytical investigation. Between August 2014 and July 2015, 353 homeless people hosted in the only public institution of the state of Goiás were interviewed about sociodemographic characteristics, knowledge and risk factors for hepatitis C, and subsequently tested for the detection of the marker HCV by immunochromatographic test (rapid test) and ELISA. In addition, monitoring of individuals reagentes for HCV was conducted through the information systems of the Unified Health System. The Poisson regression analysis was used to verify the risk factors associated with exposure to HCV with robust variance for the calculation of prevalence ratio (PR). The investigated were mostly male (81.3%), aged between 18 and 45 years (73.62%), singles (59.8%), with no income (35.7), with 5 to 9 years of study (53.3%) and self-reported brown color (61.1%). The study evidenced a knowledge deficit of the homeless people investigated in relation to the HCV transmission. The rapid test used in this study had a high index of agreement with the ELISA, whose sensitivity and specificity was 91.7% and 99.7%, respectively. The overall prevalence of HCV in the homeless people housed was 3.4% (95% CI: 1.9-5.8). It was noted that age (RP: 1.05, 95% CI: 1.02-1.09), be natural from the Southeast region (RP: 2.27, 95% CI: 1.03-5.02), overnight experience in the street (RP: 2.78, 95% CI: 1.11-6.91) and the use of injectable drugs (UID) (PR: 16.59, 95% CI: 4.23-65.09) were statistically associated with HCV infection. Of the 12 housed positive for HCV, only two sought treatment, but there was no adhesion, and another two others evolved to death as a consequence of hepatic cirrhosis due to hepatitis C. The results of the study ratify the extreme condition of homeless people and the increased risk of acquiring and disseminating the hepatitis C virus. Therefore, to prevent and / or minimize risk behaviors for HCV, it is necessary behavioral and structural interventions with combined strategies, such as health education and counseling, permanent education, provision of rapid testing and barrier methods (condom), multidisciplinary treatment, strengthening the strategy of damage reduction, evaluation of policies for homeless people, solidifying the social care equipment provided to this group, such as shelters and access to the services that comprise the health care network.Indivíduos em situação de rua apresentam risco elevado para infecções parenterais e sexuais, como a infecção causada pelo vírus da hepatite C (HCV). Este estudo objetivou investigar o perfil epidemiológico da infecção causada pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás. Trata-se de uma investigação observacional, de corte transversal e analítico. Entre agosto de 2014 e julho de 2015, 353 indivíduos em situação de rua acolhidos na única instituição pública do Estado de Goiás foram entrevistados sobre características sociodemográficas, conhecimento e fatores de risco para hepatite C, e posteriormente, testados para a detecção do marcador anti-HCV por teste imunocromatográfico (teste rápido) e ELISA. Ainda, o monitoramento dos indivíduos reagentes para anti-HCV foi realizado via sistemas de informação do Sistema Único de Saúde. A análise de regressão de Poisson foi utilizada para verificar os fatores de risco associados à exposição ao HCV com variância robusta para o cálculo de razão de prevalência (RP) ajustada. Os investigados eram majoritariamente do sexo masculino (81,3%), com idade entre 18 e 45 anos (73,62%), solteiros (59,8%), sem renda (35,7), com 5 a 9 anos de estudo (53,3%) e de cor parda autodeclarada (61,1%). O estudo evidenciou um déficit de conhecimento da população em situação de rua (PSR) investigada em relação à transmissão do HCV. O teste rápido utilizado neste estudo teve um elevado índice de concordância com o ELISA, cuja sensibilidade e especificidade foi de 91,7% e 99,7%, respectivamente. A prevalência global de anti-HCV na PSR albergada foi de 3,4% (IC 95%: 1,9–5,8). Observou-se que idade (RP: 1,05; IC 95%: 1,02–1,09), ser natural da região sudeste (RP: 2,27; IC 95%: 1,03–5,02), experiência de pernoite na rua (RP: 2,78; IC 95%: 1,11–6,91) e o uso de drogas injetáveis (UDI) (RP: 16,59; IC 95%: 4,23–65,09) foram fatores estatisticamente associados à infecção pelo HCV. Dos 12 albergados positivos para anti-HCV, somente dois buscaram tratamento, porém não houve adesão, e outros dois evoluíram para óbito em decorrência de cirrose hepática por hepatite C. Os resultados do estudo ratificam a condição de extrema vulneração dos indivíduos em situação de rua e o risco aumentado de aquisição e disseminação do vírus da hepatite C. Portanto, para prevenir e/ou minimizar os comportamentos de risco para o HCV, faz-se necessárias intervenções comportamentais e estruturais com junção de estratégias combinadas, como educação em saúde e aconselhamento, educação permanente, disponibilização de testagem rápida e métodos de barreira (preservativo), tratamento multidisciplinar, fortalecimento da estratégia de redução de danos, avaliação das políticas para a PSR, solidificação dos equipamentos sociais de cuidado disponibilizados a esse grupo, como os albergues e acesso aos serviços que compõem a rede de assistência à saúde.Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2017-06-08T12:48:10Z No. of bitstreams: 2 Dissertação - Jéssyca Pereira e Souza - 2017.pdf: 2226997 bytes, checksum: 1412453f5d9633f529d6f82693e18ed6 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-06-08T12:48:33Z (GMT) No. of bitstreams: 2 Dissertação - Jéssyca Pereira e Souza - 2017.pdf: 2226997 bytes, checksum: 1412453f5d9633f529d6f82693e18ed6 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2017-06-08T12:48:33Z (GMT). No. of bitstreams: 2 Dissertação - Jéssyca Pereira e Souza - 2017.pdf: 2226997 bytes, checksum: 1412453f5d9633f529d6f82693e18ed6 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017-04-25Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal de GoiásPrograma de Pós-graduação em Enfermagem (FEN)UFGBrasilFaculdade de Enfermagem - FEN (RG)http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessHepatite CEpidemiologiaPopulação em situação de ruaHepatitis CEpidemiologyHomeless personsCIENCIAS DA SAUDE::ENFERMAGEMInvestigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associadosInvestigation of hepatitis C virus infection in homeless people hosted in Goiânia, Goiás: prevalence and associated factorsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis45061628303650419816006006006002756753233336908714-77028265330109643272075167498588264571reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; 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dc.title.eng.fl_str_mv |
Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados |
dc.title.alternative.eng.fl_str_mv |
Investigation of hepatitis C virus infection in homeless people hosted in Goiânia, Goiás: prevalence and associated factors |
title |
Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados |
spellingShingle |
Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados Souza, Jéssyca Pereira e Hepatite C Epidemiologia População em situação de rua Hepatitis C Epidemiology Homeless persons CIENCIAS DA SAUDE::ENFERMAGEM |
title_short |
Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados |
title_full |
Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados |
title_fullStr |
Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados |
title_full_unstemmed |
Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados |
title_sort |
Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados |
author |
Souza, Jéssyca Pereira e |
author_facet |
Souza, Jéssyca Pereira e |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Matos, Marcos André de |
dc.contributor.advisor1Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4771225T1 |
dc.contributor.referee1.fl_str_mv |
Teles, Sheila Araújo |
dc.contributor.referee2.fl_str_mv |
Martins, Regina Maria Bringel |
dc.contributor.referee3.fl_str_mv |
Caetano, Karlla Antonieta Amorim |
dc.contributor.referee4.fl_str_mv |
Matos, Márcia Alves Dias de |
dc.contributor.authorLattes.fl_str_mv |
https://wwws.cnpq.br/cvlattesweb/PKG_MENU.menu?f_cod= 751A19DE30F9970674B4F2C99449CD94 |
dc.contributor.author.fl_str_mv |
Souza, Jéssyca Pereira e |
contributor_str_mv |
Matos, Marcos André de Teles, Sheila Araújo Martins, Regina Maria Bringel Caetano, Karlla Antonieta Amorim Matos, Márcia Alves Dias de |
dc.subject.por.fl_str_mv |
Hepatite C Epidemiologia População em situação de rua |
topic |
Hepatite C Epidemiologia População em situação de rua Hepatitis C Epidemiology Homeless persons CIENCIAS DA SAUDE::ENFERMAGEM |
dc.subject.eng.fl_str_mv |
Hepatitis C Epidemiology Homeless persons |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::ENFERMAGEM |
description |
Homeless people are at high risk for parental and sexual infections, such as hepatitis C virus (HCV) infection. This study aimed to investigate the epidemiological profile of the infection caused by the hepatitis C virus in homeless people housed in Goiânia, Goiás. This is an observational, cross-sectional and analytical investigation. Between August 2014 and July 2015, 353 homeless people hosted in the only public institution of the state of Goiás were interviewed about sociodemographic characteristics, knowledge and risk factors for hepatitis C, and subsequently tested for the detection of the marker HCV by immunochromatographic test (rapid test) and ELISA. In addition, monitoring of individuals reagentes for HCV was conducted through the information systems of the Unified Health System. The Poisson regression analysis was used to verify the risk factors associated with exposure to HCV with robust variance for the calculation of prevalence ratio (PR). The investigated were mostly male (81.3%), aged between 18 and 45 years (73.62%), singles (59.8%), with no income (35.7), with 5 to 9 years of study (53.3%) and self-reported brown color (61.1%). The study evidenced a knowledge deficit of the homeless people investigated in relation to the HCV transmission. The rapid test used in this study had a high index of agreement with the ELISA, whose sensitivity and specificity was 91.7% and 99.7%, respectively. The overall prevalence of HCV in the homeless people housed was 3.4% (95% CI: 1.9-5.8). It was noted that age (RP: 1.05, 95% CI: 1.02-1.09), be natural from the Southeast region (RP: 2.27, 95% CI: 1.03-5.02), overnight experience in the street (RP: 2.78, 95% CI: 1.11-6.91) and the use of injectable drugs (UID) (PR: 16.59, 95% CI: 4.23-65.09) were statistically associated with HCV infection. Of the 12 housed positive for HCV, only two sought treatment, but there was no adhesion, and another two others evolved to death as a consequence of hepatic cirrhosis due to hepatitis C. The results of the study ratify the extreme condition of homeless people and the increased risk of acquiring and disseminating the hepatitis C virus. Therefore, to prevent and / or minimize risk behaviors for HCV, it is necessary behavioral and structural interventions with combined strategies, such as health education and counseling, permanent education, provision of rapid testing and barrier methods (condom), multidisciplinary treatment, strengthening the strategy of damage reduction, evaluation of policies for homeless people, solidifying the social care equipment provided to this group, such as shelters and access to the services that comprise the health care network. |
publishDate |
2017 |
dc.date.accessioned.fl_str_mv |
2017-06-08T12:48:33Z |
dc.date.issued.fl_str_mv |
2017-04-25 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SOUZA, Jéssyca Pereira e. Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados. 2017. 110 f. Dissertação (Mestrado em Enfermagem) - Universidade Federal de Goiás, Goiânia, 2017. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/7430 |
identifier_str_mv |
SOUZA, Jéssyca Pereira e. Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados. 2017. 110 f. Dissertação (Mestrado em Enfermagem) - Universidade Federal de Goiás, Goiânia, 2017. |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/7430 |
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por |
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por |
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4506162830365041981 |
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http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Programa de Pós-graduação em Enfermagem (FEN) |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Faculdade de Enfermagem - FEN (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
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UFG |
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UFG |
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Repositório Institucional da UFG |
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Repositório Institucional da UFG |
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