SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION

Detalhes bibliográficos
Autor(a) principal: Di Filippo, Paula Alessandra
Data de Publicação: 2012
Outros Autores: Alves, Aracele Elisane, Hermeto, Larissa Correia, Santana, Aureo Evangelista
Tipo de documento: Artigo
Idioma: por
Título da fonte: Ciência animal brasileira (Online)
Texto Completo: https://revistas.ufg.br/vet/article/view/14105
Resumo: Twenty-four horses were distributed into four different groups, instrumented control (GI), duodenum obstruction (GII), ileum obstruction (GIII) and large colon obstruction (GIV). Serum and peritoneal fluid analysis of aspartate aminotransferase, creatine kinase, lactate dehydrogenase, alkaline phosphatase, inorganic phosphorus and lactate were measured. Samples were collected one hour before the surgical procedure (T0); 3 hours after the obstruction (T3ob), 1, 3, 12, 24, 120 and 168 hours after the beginning of reperfusion/deobstruction. Duodenal (GII) and ileum (GIII) obstructions changed serum and peritoneal fluid  biochemical analysis. However, only lactate, lactate dehydrogenase, creatine kinase and inorganic phosphorus concentrations were abnormal in peritoneal fluid three hours after the obstruction. The biochemical analysis of peritoneal fluid allowed a faster diagnostic of intestinal alterations than the serum analysis; hence it should be prioritized when pre-operatory colic assessment is carried out. KEYWORDS: biomarkers; colic; equine.
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spelling SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTIONINDICADORES BIOQUÍMICOS SÉRICOS E DO LÍQUIDO PERITONEAL DE EQUINOS SUBMETIDOS À OBSTRUÇÃO INTESTINALAnimal SanityequinocólicabiomarcadoresTwenty-four horses were distributed into four different groups, instrumented control (GI), duodenum obstruction (GII), ileum obstruction (GIII) and large colon obstruction (GIV). Serum and peritoneal fluid analysis of aspartate aminotransferase, creatine kinase, lactate dehydrogenase, alkaline phosphatase, inorganic phosphorus and lactate were measured. Samples were collected one hour before the surgical procedure (T0); 3 hours after the obstruction (T3ob), 1, 3, 12, 24, 120 and 168 hours after the beginning of reperfusion/deobstruction. Duodenal (GII) and ileum (GIII) obstructions changed serum and peritoneal fluid  biochemical analysis. However, only lactate, lactate dehydrogenase, creatine kinase and inorganic phosphorus concentrations were abnormal in peritoneal fluid three hours after the obstruction. The biochemical analysis of peritoneal fluid allowed a faster diagnostic of intestinal alterations than the serum analysis; hence it should be prioritized when pre-operatory colic assessment is carried out. KEYWORDS: biomarkers; colic; equine.Foram utilizados vinte e quatro equinos distribuídos em quatro grupos, controle instrumentado (GI), obstrução do duodeno (GII), do íleo (GIII) e do cólon maior (GIV). Amostras de sangue e de líquido peritoneal foram colhidas uma hora antes do procedimento cirúrgico (T0), ao final do período de três horas de obstrução (T3ob) e 1, 3, 12, 24, 120 e 168 horas após desobstrução (T1des-T168des), para determinação da atividade das enzimas aspartato aminotransferase, creatina quinase, lactato desidrogenase e fosfatase alcalina e da concentração de fósforo inorgânico e de lactato. Foram observadas alterações nas concentrações séricas e peritoneais das variáveis bioquímicas supramencionadas somente nos animais submetidos à obstrução de duodeno (GII) e de íleo (GIII). Entretanto, após três horas de obstrução só foram verificadas alterações nas concentrações peritoneais de lactato, lactato desidrogenase, fósforo inorgânico e de creatina quinase. A análise bioquímica do líquido peritoneal permitiu, quando comparada a sérica, o diagnóstico precoce de lesão entérica localizada no intestino delgado e, portanto, deve ser priorizada na avaliação pré-operatória do equino com cólica. PALAVRAS-CHAVE: biomarcadores; cólica; equino.Universidade Federal de Goiás2012-12-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionResearchAvaliado por paresPesquisa cientificaapplication/downloadtext/htmlhttps://revistas.ufg.br/vet/article/view/1410510.5216/cab.v13i4.14105Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 13 No. 4 (2012); 504-511Ciência Animal Brasileira / Brazilian Animal Science; v. 13 n. 4 (2012); 504-5111809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/14105/12724https://revistas.ufg.br/vet/article/view/14105/12725Di Filippo, Paula AlessandraAlves, Aracele ElisaneHermeto, Larissa CorreiaSantana, Aureo Evangelistainfo:eu-repo/semantics/openAccess2012-12-14T21:39:04Zoai:ojs.revistas.ufg.br:article/14105Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:55:47.694498Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true
dc.title.none.fl_str_mv SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION
INDICADORES BIOQUÍMICOS SÉRICOS E DO LÍQUIDO PERITONEAL DE EQUINOS SUBMETIDOS À OBSTRUÇÃO INTESTINAL
title SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION
spellingShingle SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION
Di Filippo, Paula Alessandra
Animal Sanity
equino
cólica
biomarcadores
title_short SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION
title_full SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION
title_fullStr SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION
title_full_unstemmed SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION
title_sort SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION
author Di Filippo, Paula Alessandra
author_facet Di Filippo, Paula Alessandra
Alves, Aracele Elisane
Hermeto, Larissa Correia
Santana, Aureo Evangelista
author_role author
author2 Alves, Aracele Elisane
Hermeto, Larissa Correia
Santana, Aureo Evangelista
author2_role author
author
author
dc.contributor.author.fl_str_mv Di Filippo, Paula Alessandra
Alves, Aracele Elisane
Hermeto, Larissa Correia
Santana, Aureo Evangelista
dc.subject.por.fl_str_mv Animal Sanity
equino
cólica
biomarcadores
topic Animal Sanity
equino
cólica
biomarcadores
description Twenty-four horses were distributed into four different groups, instrumented control (GI), duodenum obstruction (GII), ileum obstruction (GIII) and large colon obstruction (GIV). Serum and peritoneal fluid analysis of aspartate aminotransferase, creatine kinase, lactate dehydrogenase, alkaline phosphatase, inorganic phosphorus and lactate were measured. Samples were collected one hour before the surgical procedure (T0); 3 hours after the obstruction (T3ob), 1, 3, 12, 24, 120 and 168 hours after the beginning of reperfusion/deobstruction. Duodenal (GII) and ileum (GIII) obstructions changed serum and peritoneal fluid  biochemical analysis. However, only lactate, lactate dehydrogenase, creatine kinase and inorganic phosphorus concentrations were abnormal in peritoneal fluid three hours after the obstruction. The biochemical analysis of peritoneal fluid allowed a faster diagnostic of intestinal alterations than the serum analysis; hence it should be prioritized when pre-operatory colic assessment is carried out. KEYWORDS: biomarkers; colic; equine.
publishDate 2012
dc.date.none.fl_str_mv 2012-12-14
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Research
Avaliado por pares
Pesquisa cientifica
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistas.ufg.br/vet/article/view/14105
10.5216/cab.v13i4.14105
url https://revistas.ufg.br/vet/article/view/14105
identifier_str_mv 10.5216/cab.v13i4.14105
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistas.ufg.br/vet/article/view/14105/12724
https://revistas.ufg.br/vet/article/view/14105/12725
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/download
text/html
dc.publisher.none.fl_str_mv Universidade Federal de Goiás
publisher.none.fl_str_mv Universidade Federal de Goiás
dc.source.none.fl_str_mv Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 13 No. 4 (2012); 504-511
Ciência Animal Brasileira / Brazilian Animal Science; v. 13 n. 4 (2012); 504-511
1809-6891
1518-2797
reponame:Ciência animal brasileira (Online)
instname:Universidade Federal de Goiás (UFG)
instacron:UFG
instname_str Universidade Federal de Goiás (UFG)
instacron_str UFG
institution UFG
reponame_str Ciência animal brasileira (Online)
collection Ciência animal brasileira (Online)
repository.name.fl_str_mv Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv ||revistacab@gmail.com
_version_ 1799874787148824576

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