EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES

Detalhes bibliográficos
Autor(a) principal: Bonfá, Aline Fabrine
Data de Publicação: 2017
Outros Autores: Nomura, Roberto Harutomi Corrêa, do Prado, Antonia Maria Binder, da Silveira, Andressa Batista, Dornbusch, Lilian Pamela Tapia Carreno, Dornbusch, Peterson Triches
Tipo de documento: Artigo
Idioma: por
Título da fonte: Ciência animal brasileira (Online)
Texto Completo: https://revistas.ufg.br/vet/article/view/e-32307
Resumo: The platelet-rich plasma (PRP) gel is an autologous platelet concentration in a small plasma volume with the potential to improve the integration of the grafts. Eight adult equines were used, performing skin grafts, with 2.5x2.5 centimeters, on both sides of the neck, in which one was the treatment side, using the PRP gel, and the other side was the control. The animals were assessed after the surgery on days 0, 7, 14, 21, and 28, by clinical, histological, morphometric, and culture analysis of the grafts. The clinical, morphological, and biological analysis of tissue grafts revealed no significant differences between the control group and the treatment group with PRP. Histologic evaluation revealed an increase in acute inflammation on day 7 and collagen concentration on day 14, resulting from the release of growth factors by the platelets present in the gel, which did not differ in further moments. According to the experimental conditions used in this study, we concluded there were no significant differences between the side treated with PRP and the control side in skin grafts in horses.Keywords: autologous; growth factors; integration of graft; time of healing.
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spelling EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINESEFEITO DO GEL DE PLASMA RICO EM PLAQUETAS NA CICATRIZAÇÃO DE ENXERTOS CUTÂNEOS EM EQUINOSAnimal SanityClínica CirúrgicaGrandes animaisThe platelet-rich plasma (PRP) gel is an autologous platelet concentration in a small plasma volume with the potential to improve the integration of the grafts. Eight adult equines were used, performing skin grafts, with 2.5x2.5 centimeters, on both sides of the neck, in which one was the treatment side, using the PRP gel, and the other side was the control. The animals were assessed after the surgery on days 0, 7, 14, 21, and 28, by clinical, histological, morphometric, and culture analysis of the grafts. The clinical, morphological, and biological analysis of tissue grafts revealed no significant differences between the control group and the treatment group with PRP. Histologic evaluation revealed an increase in acute inflammation on day 7 and collagen concentration on day 14, resulting from the release of growth factors by the platelets present in the gel, which did not differ in further moments. According to the experimental conditions used in this study, we concluded there were no significant differences between the side treated with PRP and the control side in skin grafts in horses.Keywords: autologous; growth factors; integration of graft; time of healing.O gel de plasma rico em plaquetas (PRP) é uma concentração autóloga de plaquetas em um pequeno volume de plasma com potencial de melhorar a integração dos enxertos. Foram utilizados oito equinos adultos, realizando-se enxertos de pele com largura de 2,5 x 2,5 centímetros em cada lado do pescoço, sendo um lado o tratamento, com o uso do gel de PRP e do outro lado o controle. Os animais foram avaliados nos dias 0, 7, 14, 21 e 28 após a cirurgia por meio de avaliação clínica, histológica, morfométrica e cultura bacteriana dos enxertos. As avaliações clínicas, morfométricas e bacteriológicas dos tecidos enxertados não revelaram diferenças significativas entre o grupo controle e o grupo tratamento com PRP. A avaliação histológica revelou um aumento da inflamação aguda no momento 7 e de concentração de colágeno no momento 14 no grupo tratamento, decorrente da liberação de fatores de crescimento pelas plaquetas presentes no gel, que não diferiu nos demais momentos. De acordo com as condições experimentais utilizadas neste estudo, pode-se concluir que não houve diferenças significativas entre o lado tratado com PRP e o lado controle em enxertos cutâneos em equinos.Palavras-chave: autólogo; fatores de crescimento; integração do enxerto; tempo de cicatrização.Universidade Federal de Goiás2017-07-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPesquisa científicaResearchapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/e-3230710.1590/cab18032307Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 18 (2017): Continuous publicationCiência Animal Brasileira / Brazilian Animal Science; v. 18 (2017): Publicação contínua1809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/e-32307/23493https://revistas.ufg.br/vet/article/view/e-32307/23494Bonfá, Aline FabrineNomura, Roberto Harutomi Corrêado Prado, Antonia Maria Binderda Silveira, Andressa BatistaDornbusch, Lilian Pamela Tapia CarrenoDornbusch, Peterson Trichesinfo:eu-repo/semantics/openAccess2023-06-07T18:48:26Zoai:ojs.revistas.ufg.br:article/32307Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:56:07.706078Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true
dc.title.none.fl_str_mv EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
EFEITO DO GEL DE PLASMA RICO EM PLAQUETAS NA CICATRIZAÇÃO DE ENXERTOS CUTÂNEOS EM EQUINOS
title EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
spellingShingle EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
Bonfá, Aline Fabrine
Animal Sanity
Clínica Cirúrgica
Grandes animais
title_short EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
title_full EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
title_fullStr EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
title_full_unstemmed EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
title_sort EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
author Bonfá, Aline Fabrine
author_facet Bonfá, Aline Fabrine
Nomura, Roberto Harutomi Corrêa
do Prado, Antonia Maria Binder
da Silveira, Andressa Batista
Dornbusch, Lilian Pamela Tapia Carreno
Dornbusch, Peterson Triches
author_role author
author2 Nomura, Roberto Harutomi Corrêa
do Prado, Antonia Maria Binder
da Silveira, Andressa Batista
Dornbusch, Lilian Pamela Tapia Carreno
Dornbusch, Peterson Triches
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Bonfá, Aline Fabrine
Nomura, Roberto Harutomi Corrêa
do Prado, Antonia Maria Binder
da Silveira, Andressa Batista
Dornbusch, Lilian Pamela Tapia Carreno
Dornbusch, Peterson Triches
dc.subject.por.fl_str_mv Animal Sanity
Clínica Cirúrgica
Grandes animais
topic Animal Sanity
Clínica Cirúrgica
Grandes animais
description The platelet-rich plasma (PRP) gel is an autologous platelet concentration in a small plasma volume with the potential to improve the integration of the grafts. Eight adult equines were used, performing skin grafts, with 2.5x2.5 centimeters, on both sides of the neck, in which one was the treatment side, using the PRP gel, and the other side was the control. The animals were assessed after the surgery on days 0, 7, 14, 21, and 28, by clinical, histological, morphometric, and culture analysis of the grafts. The clinical, morphological, and biological analysis of tissue grafts revealed no significant differences between the control group and the treatment group with PRP. Histologic evaluation revealed an increase in acute inflammation on day 7 and collagen concentration on day 14, resulting from the release of growth factors by the platelets present in the gel, which did not differ in further moments. According to the experimental conditions used in this study, we concluded there were no significant differences between the side treated with PRP and the control side in skin grafts in horses.Keywords: autologous; growth factors; integration of graft; time of healing.
publishDate 2017
dc.date.none.fl_str_mv 2017-07-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Pesquisa científica
Research
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistas.ufg.br/vet/article/view/e-32307
10.1590/cab18032307
url https://revistas.ufg.br/vet/article/view/e-32307
identifier_str_mv 10.1590/cab18032307
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistas.ufg.br/vet/article/view/e-32307/23493
https://revistas.ufg.br/vet/article/view/e-32307/23494
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Universidade Federal de Goiás
publisher.none.fl_str_mv Universidade Federal de Goiás
dc.source.none.fl_str_mv Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 18 (2017): Continuous publication
Ciência Animal Brasileira / Brazilian Animal Science; v. 18 (2017): Publicação contínua
1809-6891
1518-2797
reponame:Ciência animal brasileira (Online)
instname:Universidade Federal de Goiás (UFG)
instacron:UFG
instname_str Universidade Federal de Goiás (UFG)
instacron_str UFG
institution UFG
reponame_str Ciência animal brasileira (Online)
collection Ciência animal brasileira (Online)
repository.name.fl_str_mv Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv ||revistacab@gmail.com
_version_ 1799874788721688576

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