EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Ciência animal brasileira (Online) |
Texto Completo: | https://revistas.ufg.br/vet/article/view/e-32307 |
Resumo: | The platelet-rich plasma (PRP) gel is an autologous platelet concentration in a small plasma volume with the potential to improve the integration of the grafts. Eight adult equines were used, performing skin grafts, with 2.5x2.5 centimeters, on both sides of the neck, in which one was the treatment side, using the PRP gel, and the other side was the control. The animals were assessed after the surgery on days 0, 7, 14, 21, and 28, by clinical, histological, morphometric, and culture analysis of the grafts. The clinical, morphological, and biological analysis of tissue grafts revealed no significant differences between the control group and the treatment group with PRP. Histologic evaluation revealed an increase in acute inflammation on day 7 and collagen concentration on day 14, resulting from the release of growth factors by the platelets present in the gel, which did not differ in further moments. According to the experimental conditions used in this study, we concluded there were no significant differences between the side treated with PRP and the control side in skin grafts in horses.Keywords: autologous; growth factors; integration of graft; time of healing. |
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EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINESEFEITO DO GEL DE PLASMA RICO EM PLAQUETAS NA CICATRIZAÇÃO DE ENXERTOS CUTÂNEOS EM EQUINOSAnimal SanityClínica CirúrgicaGrandes animaisThe platelet-rich plasma (PRP) gel is an autologous platelet concentration in a small plasma volume with the potential to improve the integration of the grafts. Eight adult equines were used, performing skin grafts, with 2.5x2.5 centimeters, on both sides of the neck, in which one was the treatment side, using the PRP gel, and the other side was the control. The animals were assessed after the surgery on days 0, 7, 14, 21, and 28, by clinical, histological, morphometric, and culture analysis of the grafts. The clinical, morphological, and biological analysis of tissue grafts revealed no significant differences between the control group and the treatment group with PRP. Histologic evaluation revealed an increase in acute inflammation on day 7 and collagen concentration on day 14, resulting from the release of growth factors by the platelets present in the gel, which did not differ in further moments. According to the experimental conditions used in this study, we concluded there were no significant differences between the side treated with PRP and the control side in skin grafts in horses.Keywords: autologous; growth factors; integration of graft; time of healing.O gel de plasma rico em plaquetas (PRP) é uma concentração autóloga de plaquetas em um pequeno volume de plasma com potencial de melhorar a integração dos enxertos. Foram utilizados oito equinos adultos, realizando-se enxertos de pele com largura de 2,5 x 2,5 centímetros em cada lado do pescoço, sendo um lado o tratamento, com o uso do gel de PRP e do outro lado o controle. Os animais foram avaliados nos dias 0, 7, 14, 21 e 28 após a cirurgia por meio de avaliação clínica, histológica, morfométrica e cultura bacteriana dos enxertos. As avaliações clínicas, morfométricas e bacteriológicas dos tecidos enxertados não revelaram diferenças significativas entre o grupo controle e o grupo tratamento com PRP. A avaliação histológica revelou um aumento da inflamação aguda no momento 7 e de concentração de colágeno no momento 14 no grupo tratamento, decorrente da liberação de fatores de crescimento pelas plaquetas presentes no gel, que não diferiu nos demais momentos. De acordo com as condições experimentais utilizadas neste estudo, pode-se concluir que não houve diferenças significativas entre o lado tratado com PRP e o lado controle em enxertos cutâneos em equinos.Palavras-chave: autólogo; fatores de crescimento; integração do enxerto; tempo de cicatrização.Universidade Federal de Goiás2017-07-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPesquisa científicaResearchapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/e-3230710.1590/cab18032307Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 18 (2017): Continuous publicationCiência Animal Brasileira / Brazilian Animal Science; v. 18 (2017): Publicação contínua1809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/e-32307/23493https://revistas.ufg.br/vet/article/view/e-32307/23494Bonfá, Aline FabrineNomura, Roberto Harutomi Corrêado Prado, Antonia Maria Binderda Silveira, Andressa BatistaDornbusch, Lilian Pamela Tapia CarrenoDornbusch, Peterson Trichesinfo:eu-repo/semantics/openAccess2023-06-07T18:48:26Zoai:ojs.revistas.ufg.br:article/32307Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:56:07.706078Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true |
dc.title.none.fl_str_mv |
EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES EFEITO DO GEL DE PLASMA RICO EM PLAQUETAS NA CICATRIZAÇÃO DE ENXERTOS CUTÂNEOS EM EQUINOS |
title |
EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES |
spellingShingle |
EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES Bonfá, Aline Fabrine Animal Sanity Clínica Cirúrgica Grandes animais |
title_short |
EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES |
title_full |
EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES |
title_fullStr |
EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES |
title_full_unstemmed |
EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES |
title_sort |
EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES |
author |
Bonfá, Aline Fabrine |
author_facet |
Bonfá, Aline Fabrine Nomura, Roberto Harutomi Corrêa do Prado, Antonia Maria Binder da Silveira, Andressa Batista Dornbusch, Lilian Pamela Tapia Carreno Dornbusch, Peterson Triches |
author_role |
author |
author2 |
Nomura, Roberto Harutomi Corrêa do Prado, Antonia Maria Binder da Silveira, Andressa Batista Dornbusch, Lilian Pamela Tapia Carreno Dornbusch, Peterson Triches |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Bonfá, Aline Fabrine Nomura, Roberto Harutomi Corrêa do Prado, Antonia Maria Binder da Silveira, Andressa Batista Dornbusch, Lilian Pamela Tapia Carreno Dornbusch, Peterson Triches |
dc.subject.por.fl_str_mv |
Animal Sanity Clínica Cirúrgica Grandes animais |
topic |
Animal Sanity Clínica Cirúrgica Grandes animais |
description |
The platelet-rich plasma (PRP) gel is an autologous platelet concentration in a small plasma volume with the potential to improve the integration of the grafts. Eight adult equines were used, performing skin grafts, with 2.5x2.5 centimeters, on both sides of the neck, in which one was the treatment side, using the PRP gel, and the other side was the control. The animals were assessed after the surgery on days 0, 7, 14, 21, and 28, by clinical, histological, morphometric, and culture analysis of the grafts. The clinical, morphological, and biological analysis of tissue grafts revealed no significant differences between the control group and the treatment group with PRP. Histologic evaluation revealed an increase in acute inflammation on day 7 and collagen concentration on day 14, resulting from the release of growth factors by the platelets present in the gel, which did not differ in further moments. According to the experimental conditions used in this study, we concluded there were no significant differences between the side treated with PRP and the control side in skin grafts in horses.Keywords: autologous; growth factors; integration of graft; time of healing. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-07-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Pesquisa científica Research |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistas.ufg.br/vet/article/view/e-32307 10.1590/cab18032307 |
url |
https://revistas.ufg.br/vet/article/view/e-32307 |
identifier_str_mv |
10.1590/cab18032307 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistas.ufg.br/vet/article/view/e-32307/23493 https://revistas.ufg.br/vet/article/view/e-32307/23494 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 18 (2017): Continuous publication Ciência Animal Brasileira / Brazilian Animal Science; v. 18 (2017): Publicação contínua 1809-6891 1518-2797 reponame:Ciência animal brasileira (Online) instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Ciência animal brasileira (Online) |
collection |
Ciência animal brasileira (Online) |
repository.name.fl_str_mv |
Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
||revistacab@gmail.com |
_version_ |
1799874788721688576 |