BIOCHEMICAL EVALUATION OF THE SIALIC ACID AS A TUMORAL MARKER IN HEIFERS RAISED IN AN ENDEMIC PROPERTY FOR BOVINE ENZOOTIC HEMATURIA

• Autor(a) principal: Carvalho, Marcos Coelho de
• Data de Publicação: 2011
• Outros Autores: Marçal, Wilmar Sachetin, Balarin, Mara Stipp, Fortes, Maira Salomão, Parizotto Junior, Nelson, Camargo, Mariana Itimura
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Ciência animal brasileira (Online)
• Texto Completo: https://revistas.ufg.br/vet/article/view/3431
• topic: Toxicology; Pteridium aquilinum; ácido siálico; biomarcadores; bovinos

Pteridium aquilinum (bracken fern) is one of the most concerning toxic vegetables in many countries in the world. Therefore, science aims to find ways for the epidemiological control of bovine intoxication with the purpose of making early diagnoses of Bovine Enzootic Hematuriae. Researches have shown a high correlation between the excessive production of mucoprotein by animals with Bovine Enzootic Hematuriae and sialic acid, proving that this acid acts as an inflammatory biochemical marker associated to bladder tumor development. Based on this information, serum sialic acid levels of clinically healthy Nellore heifers (control group) were statistically compared to Nellore heifers raised in bracken fern endemic properties (experimental group). The average level of serum sialic acid of the control groups was not different from the sialic acid level of the affected group (0.611± 0.225 g/L and 0.615 ± 0.258 g/L, respectively). Results obtained in the present study demonstrate no differences of the sialic acid average levels between the groups. Therefore, measurement of sialic acid serum levels was not effective as a neoplasic biochemical marker in Nellore heifers continuously fed with bracken fern.KEYWORDS: biochemical marker; bovine; Pteridium aquilinum; sialic acid.