Aspectos histopatológicos da hematúria enzoótica bovina no Brasil
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| Data de Publicação: | 2002 |
| Tipo de documento: | Dissertação |
| Idioma: | por |
| Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFRRJ |
| Texto Completo: | https://rima.ufrrj.br/jspui/handle/20.500.14407/14194 |
Resumo: | om o objetivo de descrever alterações neoplásticas e não neoplásticas ainda não reportadas e, paralelamente, reclassificá-las de acordo com nomenclatura mais completa e atual utilizada em Medicina Humana, foram estudadas , histologicamente, lesões BA bexiga de 59 bovinos com Hematúria Enzoótica Bovina (enfermidade causada pela ingestão de Pteridium aquilinum), oriundos dos Estados do Rio de Janeiro, São Paulo, Minas Gerais, Espírito Santo, Rio Grande do Sul, Santa Catarina, Paraná e Amazonas. Verificou-se, em termos qualitativos, quase uma perfeita identidade com as lesões de bexiga observadas em seres humanos. Comparações mais exatas com relação à freqüência dessas alterações ficaram prejudicadas, dadas a ocorrência de duas ou mais neoplasias em um mesmo animal e as diferenças da metodologia empregada ou do conceito de classificação. Coexistência entre neoplasias diversas, epiteliais e/ou mesenquimais, foi vista com freqüência. Neoplasias raras, ainda não descritas na bexiga de bovinos, como carcinoma trabecular com diferenciação em células de Paneth, adenoma e adenocarcinoma mesonefróides, carcinoma “signet ring” (anel de sinete), carcinoma plasmocitóide, carcinoma de células cromófobas e carcinoma transicional tipo ninhado, foram observadas na bexiga de alguns animais com HEB. Também foi identificada malignização de tumores benignos, como por exemplo a transformação de hemangiomas em hemangiossarcomas. O estudo revelou, ainda, a ocorrência de diversos tumores com anaplasia e caráter infiltrativo acentuados, incapazes, porém, de metastizarem. O esclarecimento da (s) causa (s) dessa “barreira à metástase e suas relações com a carcinogênese química induzida pelo ptaquilisídeo talvez possa ser de interesse em futuros estudos que visem combater o câncer no homem e nos animais. |
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França, Ticiana do NascimentoPeixoto, Paulo Fernando de Vargashttp://lattes.cnpq.br/3002512195318611Tokarnia , Carlos M. A. HubingerCarvalho, Eulogio C.Queiroz dehttp://lattes.cnpq.br/35458735250913152023-12-22T02:57:19Z2023-12-22T02:57:19Z2002-02-07FRANÇA, Ticiana do Nascimento. Aspectos histopatológicos da hematúria enzoótica bovina no Brasil. 2002. 85 f. Dissertação (Mestrado em Medicina Veterinária, Patologia e Ciências Clínicas) - Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica - RJ, 2002.https://rima.ufrrj.br/jspui/handle/20.500.14407/14194om o objetivo de descrever alterações neoplásticas e não neoplásticas ainda não reportadas e, paralelamente, reclassificá-las de acordo com nomenclatura mais completa e atual utilizada em Medicina Humana, foram estudadas , histologicamente, lesões BA bexiga de 59 bovinos com Hematúria Enzoótica Bovina (enfermidade causada pela ingestão de Pteridium aquilinum), oriundos dos Estados do Rio de Janeiro, São Paulo, Minas Gerais, Espírito Santo, Rio Grande do Sul, Santa Catarina, Paraná e Amazonas. Verificou-se, em termos qualitativos, quase uma perfeita identidade com as lesões de bexiga observadas em seres humanos. Comparações mais exatas com relação à freqüência dessas alterações ficaram prejudicadas, dadas a ocorrência de duas ou mais neoplasias em um mesmo animal e as diferenças da metodologia empregada ou do conceito de classificação. Coexistência entre neoplasias diversas, epiteliais e/ou mesenquimais, foi vista com freqüência. Neoplasias raras, ainda não descritas na bexiga de bovinos, como carcinoma trabecular com diferenciação em células de Paneth, adenoma e adenocarcinoma mesonefróides, carcinoma “signet ring” (anel de sinete), carcinoma plasmocitóide, carcinoma de células cromófobas e carcinoma transicional tipo ninhado, foram observadas na bexiga de alguns animais com HEB. Também foi identificada malignização de tumores benignos, como por exemplo a transformação de hemangiomas em hemangiossarcomas. O estudo revelou, ainda, a ocorrência de diversos tumores com anaplasia e caráter infiltrativo acentuados, incapazes, porém, de metastizarem. O esclarecimento da (s) causa (s) dessa “barreira à metástase e suas relações com a carcinogênese química induzida pelo ptaquilisídeo talvez possa ser de interesse em futuros estudos que visem combater o câncer no homem e nos animais.CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorThe bladder lesions of 59 cattle, from the states of Rio de Janeiro, São Paulo, Minas Gerais, Espírito Santo, Rio Grande do Sul, Santa Catarina, Paraná and Amazonas affected by Bovine Enzootic Haematuria (BEH) werw studied histologically. The objective of this study was to describe and reclassify neoplastic and non neoplastic alterations not yet reported, according to the more complete and current nomenclature used in human medicine. There was an almost complete indentity with alterations observed in the bladder of humans. Due to the ocurrence of two or more neoplasms in yhe same animal, differences of the methodology and the concept of classification was not possible. Coexistence of different types of epithelial and/or mesenchymal neoplasms was frequently seen. Rare neoplasms not yet descibed werw found in the bladder of some the animals by BEH. Those were trabecular carcinoma with differentiation in Paneth cells, mesonephroid adenoma and adenocarcinoma, “signet ring” cell carcinoma, plasmocytoid carcinoma, chromophobe cell carcinoma and nested type of transitional cell carcinoma. Malignization of benign tumors, as for example a transformation of haemangiomas into haemangiosarcomas, was Aldo observed. The study also revealed the occurrence of many tumors with anaplasia and pronounced infiltrative features, but which did not metastize. The elucidation regarding the cause(s) of this “barrier against metástases” and its relationships with the chemical carcinogenesis induced by the ptaquiloside, the active principle of bracken fern (Pteridium aquilinum), could be of interest for future research with the objective to control neoplasms in humans and animals.application/pdfporUniversidade Federal Rural do Rio de JaneiroPrograma de Pós-Graduação em Medicina Veterinária (Patologia e Ciências Clínicas)UFRRJBrasilInstituto de VeterináriaNeoplasiasbexigaPteridium aquilinumNeoplasmsbladderPteridium aquilinumMedicina VeterináriaAspectos histopatológicos da hematúria enzoótica bovina no BrasilHistopathological aspects of bovine enzootic hematuria in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisALMOND, N. Fern poisoming J. Comp. Pathol. Therapeut, 7:165-167, 1894 (Cit. FENWICK, 1988). ALONSO-AMELOT, M.E. & AVENDANO, M. Human carcinogenesis and bracken fern: review of the evidence. Curr. Med. 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Induction of intestinal and urinary bladder câncer in rats by feeding bracken fern (Pteris aquilina). J. Natn. Cancer Inst., 43(1):275-281, 1969. PAMUKÇU, A.M.; YALCINER, S.; PRICE, J.M & BRYAN, G.T. Effects of co-administration of thiamine on the incidence of urinary bladder carcinomas in rats fed bracken fern. Cancer Res., 30:2671-2674, 1970. PAMUKÇU, A.M.; WATTENBERG, L.W.; PRICE, J.M. & BRYAN, G.T. Phenothiazine inhibition of intestinal anda urinary bladder tumours induced in rats by bracken fern. J. Natl. Cancer Inst., 47:155-159, 1971. PAMAKÇU, A.M.; ETURK , E.; PRICE, J.M. & BRYAN, G.T. Lymphatic leukemia and pulmonary tumors in female swiss mice fed bracken (Pteris aquilina). Cancer Res., 32:1442-1445, 1972. PAMAKÇU, A.M.. Tumors of the Urinary Bladder. Bull. Wld. Hlth. Org. Genève:WHO. 1974. V.50. n.12 p.43-52. PAMUKÇU, A.M.; PRICE, J.M. & BRYAN, G.T. Naturally ocurring and Bracken-fern-induced bovine urinary bladder tumors. Vet. Path, 13:110-122, 1976. PAMUKÇU, A.M. & BRYAN, G.T. Pathology of the bovine urinary bladder tumors. Firat. Univ. Vet. Derg., 3(3):27-44, 1976. PAMUKÇU, A.M.; ERTURK, E. & BRYAN, G.T. Induction of urinary bladder and intestinal tumors in mice by feeding bracken fern. Ankara Univ. Vet. Fak. Derg., 24-:28-34, 1977a. PAMUKÇU, A.M.; YALCINER, S. & BRYAN, G.T. Inhibition of carcinogenic effect of bracken fern (Pteridium aquilinum) by various chemicals. Cancer, 40:2450-2454, 1977b. (Cit. FENWICK, 1988). PAMUKÇU, A.M; ERTURK, E.; YALCINER, S.; MILLI, U. & BRYAN, G.T. Carcinogenic and mutagenic activities of Milk from cows fed bracken (Pteridium aquilinum). Cancer Res., 38:1556-1560, 1978. PAMUKÇU, A.M. & BRYAN, G.T. Bracken fern, a natural urinary bladder andintestinal carcinogen. In: Naturally-Occurring Carcinogens, Mutagens and Modulators of Carcinogenises, Eds MILLER, E.C.; MILLER, J.A.; HIRONO, L; SUGIMURA, T & TAKAYAMA, S. Japan Scientific Societies Press, Tokyo, 89-99, 1979. (Cit. FENWICK, G.R. 1988). PAMUKÇU, A.M.; YALCINER, S.; HATCHER, J.F. & BRYAN, G.T. Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (Pteridium). Cancer Res., 40:3468-3472, 1980a. PAMUKÇU, A.W.; WANG, C.Y.; HATCHER, J. & BRYAN, G.T. Carcinogenicity of tannin and tannin-free extracts of bracken fern (Pteridium aquilinum) in rats. J. Natl. Cancer Inst., 65:131-136, 1980b. PARKER, W.H. & McCREA, C.T. Bracken (Pteris aquilina) poisoning of sheep in the North York Moors. Vet. Record, 77(30): 861-865, 1965. PENBERTHY, J. Vegetable poisoning (?) simulating anthrax in cattle. J. Comp. Pathol. Therap., 6:266-275, 1893 (Cit FENWICK, G.R. 1988). PIRIE, H.M. Unusual ocurrence of squamous carcinoma of the upper alimentary tract in cattle in britain. Res. Vet. Sci., 15:135-138, 1973. PLOWRIGHT, W. Malignant neoplasia of the oesophagus e numen of cattle in kenya. J. Comp. Pathol. Therap., 65:108-114, 1955. PLOWRIGHT, W.; LINSELL, C.A. & PEERS, F.G. A focus of rumenal cancer in kenyan cattle. Brit. J. 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| dc.title.por.fl_str_mv |
Aspectos histopatológicos da hematúria enzoótica bovina no Brasil |
| dc.title.alternative.eng.fl_str_mv |
Histopathological aspects of bovine enzootic hematuria in Brazil |
| title |
Aspectos histopatológicos da hematúria enzoótica bovina no Brasil |
| spellingShingle |
Aspectos histopatológicos da hematúria enzoótica bovina no Brasil França, Ticiana do Nascimento Neoplasias bexiga Pteridium aquilinum Neoplasms bladder Pteridium aquilinum Medicina Veterinária |
| title_short |
Aspectos histopatológicos da hematúria enzoótica bovina no Brasil |
| title_full |
Aspectos histopatológicos da hematúria enzoótica bovina no Brasil |
| title_fullStr |
Aspectos histopatológicos da hematúria enzoótica bovina no Brasil |
| title_full_unstemmed |
Aspectos histopatológicos da hematúria enzoótica bovina no Brasil |
| title_sort |
Aspectos histopatológicos da hematúria enzoótica bovina no Brasil |
| author |
França, Ticiana do Nascimento |
| author_facet |
França, Ticiana do Nascimento |
| author_role |
author |
| dc.contributor.author.fl_str_mv |
França, Ticiana do Nascimento |
| dc.contributor.advisor1.fl_str_mv |
Peixoto, Paulo Fernando de Vargas |
| dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/3002512195318611 |
| dc.contributor.referee1.fl_str_mv |
Tokarnia , Carlos M. A. Hubinger |
| dc.contributor.referee2.fl_str_mv |
Carvalho, Eulogio C.Queiroz de |
| dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/3545873525091315 |
| contributor_str_mv |
Peixoto, Paulo Fernando de Vargas Tokarnia , Carlos M. A. Hubinger Carvalho, Eulogio C.Queiroz de |
| dc.subject.por.fl_str_mv |
Neoplasias bexiga Pteridium aquilinum |
| topic |
Neoplasias bexiga Pteridium aquilinum Neoplasms bladder Pteridium aquilinum Medicina Veterinária |
| dc.subject.eng.fl_str_mv |
Neoplasms bladder Pteridium aquilinum |
| dc.subject.cnpq.fl_str_mv |
Medicina Veterinária |
| description |
om o objetivo de descrever alterações neoplásticas e não neoplásticas ainda não reportadas e, paralelamente, reclassificá-las de acordo com nomenclatura mais completa e atual utilizada em Medicina Humana, foram estudadas , histologicamente, lesões BA bexiga de 59 bovinos com Hematúria Enzoótica Bovina (enfermidade causada pela ingestão de Pteridium aquilinum), oriundos dos Estados do Rio de Janeiro, São Paulo, Minas Gerais, Espírito Santo, Rio Grande do Sul, Santa Catarina, Paraná e Amazonas. Verificou-se, em termos qualitativos, quase uma perfeita identidade com as lesões de bexiga observadas em seres humanos. Comparações mais exatas com relação à freqüência dessas alterações ficaram prejudicadas, dadas a ocorrência de duas ou mais neoplasias em um mesmo animal e as diferenças da metodologia empregada ou do conceito de classificação. Coexistência entre neoplasias diversas, epiteliais e/ou mesenquimais, foi vista com freqüência. Neoplasias raras, ainda não descritas na bexiga de bovinos, como carcinoma trabecular com diferenciação em células de Paneth, adenoma e adenocarcinoma mesonefróides, carcinoma “signet ring” (anel de sinete), carcinoma plasmocitóide, carcinoma de células cromófobas e carcinoma transicional tipo ninhado, foram observadas na bexiga de alguns animais com HEB. Também foi identificada malignização de tumores benignos, como por exemplo a transformação de hemangiomas em hemangiossarcomas. O estudo revelou, ainda, a ocorrência de diversos tumores com anaplasia e caráter infiltrativo acentuados, incapazes, porém, de metastizarem. O esclarecimento da (s) causa (s) dessa “barreira à metástase e suas relações com a carcinogênese química induzida pelo ptaquilisídeo talvez possa ser de interesse em futuros estudos que visem combater o câncer no homem e nos animais. |
| publishDate |
2002 |
| dc.date.issued.fl_str_mv |
2002-02-07 |
| dc.date.accessioned.fl_str_mv |
2023-12-22T02:57:19Z |
| dc.date.available.fl_str_mv |
2023-12-22T02:57:19Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
| format |
masterThesis |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
FRANÇA, Ticiana do Nascimento. Aspectos histopatológicos da hematúria enzoótica bovina no Brasil. 2002. 85 f. Dissertação (Mestrado em Medicina Veterinária, Patologia e Ciências Clínicas) - Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica - RJ, 2002. |
| dc.identifier.uri.fl_str_mv |
https://rima.ufrrj.br/jspui/handle/20.500.14407/14194 |
| identifier_str_mv |
FRANÇA, Ticiana do Nascimento. Aspectos histopatológicos da hematúria enzoótica bovina no Brasil. 2002. 85 f. Dissertação (Mestrado em Medicina Veterinária, Patologia e Ciências Clínicas) - Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica - RJ, 2002. |
| url |
https://rima.ufrrj.br/jspui/handle/20.500.14407/14194 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.references.por.fl_str_mv |
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