ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Ciência animal brasileira (Online) |
Texto Completo: | https://revistas.ufg.br/vet/article/view/e-44583 |
Resumo: | The aim of the present study was to evaluate the efficacy of ivermectin at 2% in horses, through coproparasitological and hematological exams. The experiment was performed at a farm in the city of Uberlândia, Minas Gerais State. Twenty-four horses were used, ranging from 3 to 8 years of age, divided into 2 groups according to EPG values. EPG counts and coprocultures were performed on days D0, D+7 and D+14. The animals were treated with the ivermectin 2%-based paste formulation at a dose of 200 mcg/kg, orally. Blood samples were collected on days D0, D+7 and D+14 for evaluation of haematological parameters. The presence of eggs that are characteristic of the Strongylidae family and the identification of larvae that are characteristic of cyathostomins demonstrated the parasitism of the animals by small strongyles. At D+7 and D+14 there was a significant reduction of EPG in the treated group with an efficacy of 99.5 and 99.7%, respectively. A tendency of the erythrocyte framework to remain close to the lower limits was observed, besides a slight leukocytosis, with neutrophils close to the highest values. It can be inferred that ivermectin is effective against cyastostomines, and no significant haematological changes were observed.Keywords: Cyathostomins; EPG; Horses; Nematodes |
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ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMSEficácia anti-helmíntica da ivermectina em equinos: exames coproparasitológicos e hematológicosThe aim of the present study was to evaluate the efficacy of ivermectin at 2% in horses, through coproparasitological and hematological exams. The experiment was performed at a farm in the city of Uberlândia, Minas Gerais State. Twenty-four horses were used, ranging from 3 to 8 years of age, divided into 2 groups according to EPG values. EPG counts and coprocultures were performed on days D0, D+7 and D+14. The animals were treated with the ivermectin 2%-based paste formulation at a dose of 200 mcg/kg, orally. Blood samples were collected on days D0, D+7 and D+14 for evaluation of haematological parameters. The presence of eggs that are characteristic of the Strongylidae family and the identification of larvae that are characteristic of cyathostomins demonstrated the parasitism of the animals by small strongyles. At D+7 and D+14 there was a significant reduction of EPG in the treated group with an efficacy of 99.5 and 99.7%, respectively. A tendency of the erythrocyte framework to remain close to the lower limits was observed, besides a slight leukocytosis, with neutrophils close to the highest values. It can be inferred that ivermectin is effective against cyastostomines, and no significant haematological changes were observed.Keywords: Cyathostomins; EPG; Horses; NematodesO objetivo do presente estudo foi avaliar a eficácia da ivermectina a 2% em equinos, através de exames coproparasitológicos e hematológicos. O experimento foi realizado em uma fazenda no município de Uberlândia, MG. Foram utilizados 24 equinos, de três a oito anos, divididos em dois grupos, conforme valores dos OPG. Contagens de OPG e coproculturas foram realizadas nos dias D0, D+7 e D+14. Os animais foram tratados com a formulação pasta a base de ivermectina 2%, na dose de 200 mcg/kg, via oral. Amostras de sangue foram coletadas nos dias D0, D+7 e D+14 para avaliação dos parâmetros hematológicos. A presença de ovos, característicos da família Strongylidae e identificação de larvas características de ciatostomíneos demonstrou o parasitismo dos animais por pequenos estrôngilos. Nos D+7 e D+14 houve a redução significativa do OPG no grupo tratado com eficácia de 99,5 e 99,7%, respectivamente. Observou-se tendência do quadro eritrocitário manter-se próximo aos limites inferiores e discreta leucocitose com neutrófilos próximos dos valores superiores. Pode-se inferir que a ivermectina é eficaz contra os ciatostomíneos e alterações hematológicas significativas não foram observadas.Palavras-chave: Ciatostomíneos; Equinos; Nematódeos; OPGUniversidade Federal de Goiás2018-06-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttps://revistas.ufg.br/vet/article/view/e-4458310.1590/cab19044583Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 19 (2018): Continuous publication; 1-12Ciência Animal Brasileira / Brazilian Animal Science; v. 19 (2018): Publicação contínua; 1-121809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/e-44583/25652https://revistas.ufg.br/vet/article/view/e-44583/25653Copyright (c) 2018 Ciência Animal Brasileirainfo:eu-repo/semantics/openAccessCristino Barbosa, FernandoJunior Oliveira, WilsonCristina Costa, PriscilaVicente Mundim, Antonio2023-03-23T18:50:39Zoai:ojs.revistas.ufg.br:article/44583Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:56:16.739789Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true |
dc.title.none.fl_str_mv |
ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS Eficácia anti-helmíntica da ivermectina em equinos: exames coproparasitológicos e hematológicos |
title |
ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS |
spellingShingle |
ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS Cristino Barbosa, Fernando |
title_short |
ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS |
title_full |
ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS |
title_fullStr |
ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS |
title_full_unstemmed |
ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS |
title_sort |
ANTIHELMINTHIC EFFICACY OF IVERMECTIN IN HORSES: COPROPARASITOLOGICAL AND HEMATOLOGICAL EXAMS |
author |
Cristino Barbosa, Fernando |
author_facet |
Cristino Barbosa, Fernando Junior Oliveira, Wilson Cristina Costa, Priscila Vicente Mundim, Antonio |
author_role |
author |
author2 |
Junior Oliveira, Wilson Cristina Costa, Priscila Vicente Mundim, Antonio |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Cristino Barbosa, Fernando Junior Oliveira, Wilson Cristina Costa, Priscila Vicente Mundim, Antonio |
description |
The aim of the present study was to evaluate the efficacy of ivermectin at 2% in horses, through coproparasitological and hematological exams. The experiment was performed at a farm in the city of Uberlândia, Minas Gerais State. Twenty-four horses were used, ranging from 3 to 8 years of age, divided into 2 groups according to EPG values. EPG counts and coprocultures were performed on days D0, D+7 and D+14. The animals were treated with the ivermectin 2%-based paste formulation at a dose of 200 mcg/kg, orally. Blood samples were collected on days D0, D+7 and D+14 for evaluation of haematological parameters. The presence of eggs that are characteristic of the Strongylidae family and the identification of larvae that are characteristic of cyathostomins demonstrated the parasitism of the animals by small strongyles. At D+7 and D+14 there was a significant reduction of EPG in the treated group with an efficacy of 99.5 and 99.7%, respectively. A tendency of the erythrocyte framework to remain close to the lower limits was observed, besides a slight leukocytosis, with neutrophils close to the highest values. It can be inferred that ivermectin is effective against cyastostomines, and no significant haematological changes were observed.Keywords: Cyathostomins; EPG; Horses; Nematodes |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-06-05 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistas.ufg.br/vet/article/view/e-44583 10.1590/cab19044583 |
url |
https://revistas.ufg.br/vet/article/view/e-44583 |
identifier_str_mv |
10.1590/cab19044583 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistas.ufg.br/vet/article/view/e-44583/25652 https://revistas.ufg.br/vet/article/view/e-44583/25653 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Ciência Animal Brasileira info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Ciência Animal Brasileira |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 19 (2018): Continuous publication; 1-12 Ciência Animal Brasileira / Brazilian Animal Science; v. 19 (2018): Publicação contínua; 1-12 1809-6891 1518-2797 reponame:Ciência animal brasileira (Online) instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Ciência animal brasileira (Online) |
collection |
Ciência animal brasileira (Online) |
repository.name.fl_str_mv |
Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
||revistacab@gmail.com |
_version_ |
1799874789333008384 |