Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review

Detalhes bibliográficos
Autor(a) principal: Araújo Lucca, Ana Beatriz
Data de Publicação: 2020
Outros Autores: Carvalho, Marina Fernandes, Silva, Vítor Rodrigues Ribeiro, Magalhães, Horrana Alves, Costa, Luiza Mageste, Guerrieri, Yzamara Dutra, Bonomo, Larissa de Freitas, Silva, Maisa
Tipo de documento: Artigo
Idioma: por
Título da fonte: HU Revista (Online)
Texto Completo: https://periodicos.ufjf.br/index.php/hurevista/article/view/32296
Resumo: Introduction: In a context of increasing prevalence of metabolic syndrome (SM), non-pharmacological interventions, such as lifestyle changes, are recommended for prevention and treatment. New alternatives for this purpose are natural products, which can protect the body against oxidative stress and improve metabolic parameters. Objective: To evaluate the results of clinical studies in patients with SM from supplementation with natural products. Material and Methods: Search for articles published from 2015 to 2020 in Portuguese and English was carried out, using the Scientific Electronic Library Online (SciELO), Public Medline (PubMed), Web of Science, Scopus, Embase and Virtual Health Library databases. The terms used for the research were: metabolic syndrome; oxidative stress; natural products. Results: Of the 47 randomized clinical trials found, eight were included. Most studies revealed a beneficial association between the consumption of natural products and the control of parameters related to SM. In six of the eight articles, the intake of natural products had a positive effect on the lipid profile; and in three studies the beneficial effects on waist circumference were verified. In addition, in six of the eight clinical trials, natural products decreased some marker of oxidative stress. Conclusion: This review, therefore, provides data suggesting that supplementation of natural products to the diet is a factor in the control and prevention of SM. However, larger, more homogeneous studies with a greater number of evaluated parameters are necessary to build robust evidence on the effects of these products on patients with this syndrome.
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spelling Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic reviewEfeitos de produtos naturais sobre parâmetros metabólicos e do estresse oxidativo em pacientes com síndrome metabólica: uma revisão sistemáticaBiological ProductsOxidative StressMetabolic SyndromeProdutos BiológicosEstresse OxidativoSíndrome MetabólicaIntroduction: In a context of increasing prevalence of metabolic syndrome (SM), non-pharmacological interventions, such as lifestyle changes, are recommended for prevention and treatment. New alternatives for this purpose are natural products, which can protect the body against oxidative stress and improve metabolic parameters. Objective: To evaluate the results of clinical studies in patients with SM from supplementation with natural products. Material and Methods: Search for articles published from 2015 to 2020 in Portuguese and English was carried out, using the Scientific Electronic Library Online (SciELO), Public Medline (PubMed), Web of Science, Scopus, Embase and Virtual Health Library databases. The terms used for the research were: metabolic syndrome; oxidative stress; natural products. Results: Of the 47 randomized clinical trials found, eight were included. Most studies revealed a beneficial association between the consumption of natural products and the control of parameters related to SM. In six of the eight articles, the intake of natural products had a positive effect on the lipid profile; and in three studies the beneficial effects on waist circumference were verified. In addition, in six of the eight clinical trials, natural products decreased some marker of oxidative stress. Conclusion: This review, therefore, provides data suggesting that supplementation of natural products to the diet is a factor in the control and prevention of SM. However, larger, more homogeneous studies with a greater number of evaluated parameters are necessary to build robust evidence on the effects of these products on patients with this syndrome.Introdução: Em um contexto de aumento de prevalência da síndrome metabólica (SM), intervenções não farmacológicas, como mudanças de estilo de vida, são recomendadas para prevenção e tratamento. Novas alternativas para esse fim são os produtos naturais, que podem proteger o organismo contra o estresse oxidativo e melhorar parâmetros metabólicos. Objetivo: Avaliar os resultados de estudos clínicos em pacientes com SM a partir da suplementação com produtos naturais. Material e Métodos: Realizou-se a busca por artigos publicados de 2015 a 2020 nos idiomas português e inglês, sendo utilizadas as bases de dados Scientific Electronic Library Online (SciELO), Public Medline (PubMed), Web of Science, Scopus, Embase e Biblioteca Virtual de Saúde. Os termos utilizados para a pesquisa foram: síndrome metabólica; estresse oxidativo; produtos naturais. Resultados: Dos 47 ensaios clínicos randomizados encontrados, oito foram incluídos. A maioria dos estudos revelou uma associação benéfica entre o consumo de produtos naturais e o controle de parâmetros relacionados à SM. Em seis dos oito artigos, a ingestão de produtos naturais apresentou efeito positivo no perfil lipídico; e em três estudos os efeitos benéficos na circunferência abdominal foi verificado. Além disso, em seis dos oito ensaios clínicos, os produtos naturais diminuíram algum marcador de estresse oxidativo. Conclusão: Esta revisão, portanto, fornece dados sugestivos de que a suplementação de produtos naturais à dieta seja um fator de controle e prevenção da SM. Porém, estudos maiores, mais homogêneos e com maior número de parâmetros avaliados são necessários para construção de evidências robustas sobre os efeitos desses produtos em pacientes com essa síndrome.Editora UFJF2020-12-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtRevSistapplication/pdfhttps://periodicos.ufjf.br/index.php/hurevista/article/view/3229610.34019/1982-8047.2020.v46.32296HU Revista; v. 46 (2020); 1-111982-80470103-3123reponame:HU Revista (Online)instname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFporhttps://periodicos.ufjf.br/index.php/hurevista/article/view/32296/21622Copyright (c) 2020 Ana Beatriz Araújo Lucca, Marina Fernandes Carvalho, Vítor Rodrigues Ribeiro Silva, Horrana Alves Magalhães, Luiza Mageste Costa, Yzamara Dutra Guerrieri, Larissa de Freitas Bonomo, Maisa Silvainfo:eu-repo/semantics/openAccessAraújo Lucca, Ana Beatriz Carvalho, Marina FernandesSilva, Vítor Rodrigues Ribeiro Magalhães, Horrana Alves Costa, Luiza Mageste Guerrieri, Yzamara Dutra Bonomo, Larissa de FreitasSilva, Maisa2020-12-08T19:12:39Zoai:periodicos.ufjf.br:article/32296Revistahttps://periodicos.ufjf.br/index.php/hurevistaPUBhttps://periodicos.ufjf.br/index.php/hurevista/oairevista.hurevista@ufjf.edu.br1982-80470103-3123opendoar:2020-12-08T19:12:39HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)false
dc.title.none.fl_str_mv Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review
Efeitos de produtos naturais sobre parâmetros metabólicos e do estresse oxidativo em pacientes com síndrome metabólica: uma revisão sistemática
title Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review
spellingShingle Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review
Araújo Lucca, Ana Beatriz
Biological Products
Oxidative Stress
Metabolic Syndrome
Produtos Biológicos
Estresse Oxidativo
Síndrome Metabólica
title_short Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review
title_full Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review
title_fullStr Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review
title_full_unstemmed Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review
title_sort Effects of natural products on metabolic parameters and oxidative stress in patients with metabolic syndrome: a systematic review
author Araújo Lucca, Ana Beatriz
author_facet Araújo Lucca, Ana Beatriz
Carvalho, Marina Fernandes
Silva, Vítor Rodrigues Ribeiro
Magalhães, Horrana Alves
Costa, Luiza Mageste
Guerrieri, Yzamara Dutra
Bonomo, Larissa de Freitas
Silva, Maisa
author_role author
author2 Carvalho, Marina Fernandes
Silva, Vítor Rodrigues Ribeiro
Magalhães, Horrana Alves
Costa, Luiza Mageste
Guerrieri, Yzamara Dutra
Bonomo, Larissa de Freitas
Silva, Maisa
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Araújo Lucca, Ana Beatriz
Carvalho, Marina Fernandes
Silva, Vítor Rodrigues Ribeiro
Magalhães, Horrana Alves
Costa, Luiza Mageste
Guerrieri, Yzamara Dutra
Bonomo, Larissa de Freitas
Silva, Maisa
dc.subject.por.fl_str_mv Biological Products
Oxidative Stress
Metabolic Syndrome
Produtos Biológicos
Estresse Oxidativo
Síndrome Metabólica
topic Biological Products
Oxidative Stress
Metabolic Syndrome
Produtos Biológicos
Estresse Oxidativo
Síndrome Metabólica
description Introduction: In a context of increasing prevalence of metabolic syndrome (SM), non-pharmacological interventions, such as lifestyle changes, are recommended for prevention and treatment. New alternatives for this purpose are natural products, which can protect the body against oxidative stress and improve metabolic parameters. Objective: To evaluate the results of clinical studies in patients with SM from supplementation with natural products. Material and Methods: Search for articles published from 2015 to 2020 in Portuguese and English was carried out, using the Scientific Electronic Library Online (SciELO), Public Medline (PubMed), Web of Science, Scopus, Embase and Virtual Health Library databases. The terms used for the research were: metabolic syndrome; oxidative stress; natural products. Results: Of the 47 randomized clinical trials found, eight were included. Most studies revealed a beneficial association between the consumption of natural products and the control of parameters related to SM. In six of the eight articles, the intake of natural products had a positive effect on the lipid profile; and in three studies the beneficial effects on waist circumference were verified. In addition, in six of the eight clinical trials, natural products decreased some marker of oxidative stress. Conclusion: This review, therefore, provides data suggesting that supplementation of natural products to the diet is a factor in the control and prevention of SM. However, larger, more homogeneous studies with a greater number of evaluated parameters are necessary to build robust evidence on the effects of these products on patients with this syndrome.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-08
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://periodicos.ufjf.br/index.php/hurevista/article/view/32296
10.34019/1982-8047.2020.v46.32296
url https://periodicos.ufjf.br/index.php/hurevista/article/view/32296
identifier_str_mv 10.34019/1982-8047.2020.v46.32296
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufjf.br/index.php/hurevista/article/view/32296/21622
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Editora UFJF
publisher.none.fl_str_mv Editora UFJF
dc.source.none.fl_str_mv HU Revista; v. 46 (2020); 1-11
1982-8047
0103-3123
reponame:HU Revista (Online)
instname:Universidade Federal de Juiz de Fora (UFJF)
instacron:UFJF
instname_str Universidade Federal de Juiz de Fora (UFJF)
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institution UFJF
reponame_str HU Revista (Online)
collection HU Revista (Online)
repository.name.fl_str_mv HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)
repository.mail.fl_str_mv revista.hurevista@ufjf.edu.br
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