Innate and adaptive immune responses against coronavirus
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFLA |
Texto Completo: | http://repositorio.ufla.br/jspui/handle/1/43538 |
Resumo: | Coronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however, uncontrolled immune responses can result in aggravating acute lung injury and significant immunopathology. Gaining profound understanding about the interaction between CoVs and the innate and adaptive immune systems could be a critical step in the field of treatment. In this review, we present an update on the host innate and adaptive immune responses against SARS-CoV, MERS-CoV and newly appeared SARS-CoV-2. |
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Innate and adaptive immune responses against coronavirusCOVID-19CoronavirusSARS-CoV-2Innate immune responseAdaptive immune responseMonoclonal antibody therapyConvalescent plasma therapyResposta imune inataResposta imune adaptativaTerapia de anticorpo monoclonalTerapia de plasma convalescenteCoronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however, uncontrolled immune responses can result in aggravating acute lung injury and significant immunopathology. Gaining profound understanding about the interaction between CoVs and the innate and adaptive immune systems could be a critical step in the field of treatment. In this review, we present an update on the host innate and adaptive immune responses against SARS-CoV, MERS-CoV and newly appeared SARS-CoV-2.Elsevier2020-10-22T17:23:10Z2020-10-22T17:23:10Z2020info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfHOSSEINI, A. et al. Innate and adaptive immune responses against coronavirus. Biomedicine & Pharmacotherapy, Paris, 2020. DOI: https://doi.org/10.1016/j.biopha.2020.110859.http://repositorio.ufla.br/jspui/handle/1/43538Biomedicine & Pharmacotherapyreponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessHosseini, ArezooHashemi, VidaShomali, NavidAsghari, FaezehGharibi, TohidAkbari, MortezaGholizadeh, SaberJafari, Abbaseng2020-10-22T17:23:10Zoai:localhost:1/43538Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2020-10-22T17:23:10Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false |
dc.title.none.fl_str_mv |
Innate and adaptive immune responses against coronavirus |
title |
Innate and adaptive immune responses against coronavirus |
spellingShingle |
Innate and adaptive immune responses against coronavirus Hosseini, Arezoo COVID-19 Coronavirus SARS-CoV-2 Innate immune response Adaptive immune response Monoclonal antibody therapy Convalescent plasma therapy Resposta imune inata Resposta imune adaptativa Terapia de anticorpo monoclonal Terapia de plasma convalescente |
title_short |
Innate and adaptive immune responses against coronavirus |
title_full |
Innate and adaptive immune responses against coronavirus |
title_fullStr |
Innate and adaptive immune responses against coronavirus |
title_full_unstemmed |
Innate and adaptive immune responses against coronavirus |
title_sort |
Innate and adaptive immune responses against coronavirus |
author |
Hosseini, Arezoo |
author_facet |
Hosseini, Arezoo Hashemi, Vida Shomali, Navid Asghari, Faezeh Gharibi, Tohid Akbari, Morteza Gholizadeh, Saber Jafari, Abbas |
author_role |
author |
author2 |
Hashemi, Vida Shomali, Navid Asghari, Faezeh Gharibi, Tohid Akbari, Morteza Gholizadeh, Saber Jafari, Abbas |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Hosseini, Arezoo Hashemi, Vida Shomali, Navid Asghari, Faezeh Gharibi, Tohid Akbari, Morteza Gholizadeh, Saber Jafari, Abbas |
dc.subject.por.fl_str_mv |
COVID-19 Coronavirus SARS-CoV-2 Innate immune response Adaptive immune response Monoclonal antibody therapy Convalescent plasma therapy Resposta imune inata Resposta imune adaptativa Terapia de anticorpo monoclonal Terapia de plasma convalescente |
topic |
COVID-19 Coronavirus SARS-CoV-2 Innate immune response Adaptive immune response Monoclonal antibody therapy Convalescent plasma therapy Resposta imune inata Resposta imune adaptativa Terapia de anticorpo monoclonal Terapia de plasma convalescente |
description |
Coronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however, uncontrolled immune responses can result in aggravating acute lung injury and significant immunopathology. Gaining profound understanding about the interaction between CoVs and the innate and adaptive immune systems could be a critical step in the field of treatment. In this review, we present an update on the host innate and adaptive immune responses against SARS-CoV, MERS-CoV and newly appeared SARS-CoV-2. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-10-22T17:23:10Z 2020-10-22T17:23:10Z 2020 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
HOSSEINI, A. et al. Innate and adaptive immune responses against coronavirus. Biomedicine & Pharmacotherapy, Paris, 2020. DOI: https://doi.org/10.1016/j.biopha.2020.110859. http://repositorio.ufla.br/jspui/handle/1/43538 |
identifier_str_mv |
HOSSEINI, A. et al. Innate and adaptive immune responses against coronavirus. Biomedicine & Pharmacotherapy, Paris, 2020. DOI: https://doi.org/10.1016/j.biopha.2020.110859. |
url |
http://repositorio.ufla.br/jspui/handle/1/43538 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
Biomedicine & Pharmacotherapy reponame:Repositório Institucional da UFLA instname:Universidade Federal de Lavras (UFLA) instacron:UFLA |
instname_str |
Universidade Federal de Lavras (UFLA) |
instacron_str |
UFLA |
institution |
UFLA |
reponame_str |
Repositório Institucional da UFLA |
collection |
Repositório Institucional da UFLA |
repository.name.fl_str_mv |
Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA) |
repository.mail.fl_str_mv |
nivaldo@ufla.br || repositorio.biblioteca@ufla.br |
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1815438971689238528 |