Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFMA |
Texto Completo: | https://tedebc.ufma.br/jspui/handle/tede/tede/3194 |
Resumo: | Eating practices represent one of the main components of the lifestyle to be favor the development of obesity and its comorbidities and metabolic disorders important factors that trigger the inflammatory process. The first article of this thesis aimed at identifying the main dietary patterns (BPs) of adolescents and verifying association with inflammatory biomarkers. It was a cross-sectional study with 391 adolescents aged 17 and 18 from public schools in São Luís-MA. Were build latent variables “Socioeconomic Conditions” (SES) and “inflammation”, consisting of the biomarkers interleukin-1β, interleukin-6 and interleukin-8. Dietary patterns were identified by factor analysis by main components. Modeling of structural equations to assess factors associated with inflammatory biomarkers. Three PAs were extracted (western, basic Brazilian and healthy). Not found association between PAS and “inflammation”. However, excess weight was positively associated with “inflammation” (CP = 0.281; p = 0.002). The second article objective to evaluate the relative validity of the Food Frequency Questionnaire (FFQ) used in the RPS Cohort to assess food intake of adolescents in São Luís- BAD. Study developed with 152 adolescents aged 17 and 18 years old. To the validation of the FFQ, the average of three 24-hour recalls (R24h) was used as reference method. The paired t-Student test was used to verify differences between the instruments. To measure concordance, coefficients of Pearson correlation, intraclass correlation coefficient (ICC), weighted Kappa and Bland-Altman graphics. Significance level <5% was adopted. When compared with R24h, the FFQ evaluated overestimated the consumption of most nutrients. You Pearson's correlation coefficients after adjustment for energy consumption and attenuation ranged from 0.06 - 0.43 and, despite the weak / moderate correlation, were significant for the nutrients iron, calcium, riboflavin, sodium, saturated fatty acids, niacin and vitamin C. Adjusted and diluted intraclass correlation coefficients (ICC) varied from 0.01 - 0.31 and the weighted kappa of the energy-adjusted variables ranged from 0.01 - 0.46. Agreement analyzes were significant for Vitamin C, fiber, calcium, riboflavin, niacin and sodium, lipids and iron. This FFQ was relatively valid acceptable for lipid nutrients, saturated fatty acids, fibers, calcium, iron, riboflavin, niacin, vitamin C and sodium. The third article aimed to identify adolescents' PAs and assess factors associated with inflammatory biomarkers, through a cross-sectional study aligned with the RPS cohort, with data from São Luís-MA. 511 adolescents aged 18 and 19 years were evaluated. PAs were identified by factor analysis by main components. To assess nutritional status, we used Body Mass Index (BMI) and body fat percentage (% BF), assessed by the air displacement plethysmography method. Modeling was done hierarchized using Linear Regression to estimate the Beta coefficient (β) of independent variables with the dependent variables, Interleukin-6 (IL-6) and Ultra-sensitive C-reactive protein (hs-CRP). Five dietary patterns were identified: energy-dense, sugary drinks and breakfast cereals, prudent, common Brazilian and alcoholic and energy drinks. The “prudent” pattern pointed to the association with the subclinical inflammation assessed using IL-6, this pattern being considered a protective factor for inflammation (β = -0.11; p value = 0.040). PAs “Common Brazilian” and “alcoholic and energy drinks” were indirectly associated the increase in IL-6, mediated by nutritional status. CRP levels were directly associated with BMI (β = 0.36; p value = <0.001) and% BG (β = 0.02; p value = 0.014). Subclinical inflammation was associated with nutritional status and prudent BP, in which adolescents with higher BMI and% BF had higher concentrations of CRP-us and those with greater adherence to prudent AP had lower concentrations of IL-6, thus being a protector of subclinical inflammation. |
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FRANÇA, Ana Karina Teixeira da Cunha880995124-72http://lattes.cnpq.br/8389486900285691SILVA, Antônio Augusto Moura da176754643-20http://lattes.cnpq.br/8652081312944025FRANÇA, Ana Karina Teixeira da Cunhahttp://lattes.cnpq.br/8389486900285691SILVA, Antônio Augusto Moura dahttp://lattes.cnpq.br/8652081312944025RIBEIRO, Cecília Claudia Costahttp://lattes.cnpq.br/1783658679814263NASCIMENTO, Joelma Ximenes Prado Teixeirahttp://lattes.cnpq.br/9553463144721017MACHADO, Soraia Pinheirohttp://lattes.cnpq.br/9623777040675359045209623-58BOGEA, Eduarda Gomes2021-02-17T15:14:56Z2019-11-26BOGEA, Eduarda Gomes. Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes. 2019. 200 f. Tese (Programa de Pós-Graduação em Saúde Coletiva/CCBS) - Universidade Federal do Maranhão, São Luís, 2019.https://tedebc.ufma.br/jspui/handle/tede/tede/3194Eating practices represent one of the main components of the lifestyle to be favor the development of obesity and its comorbidities and metabolic disorders important factors that trigger the inflammatory process. The first article of this thesis aimed at identifying the main dietary patterns (BPs) of adolescents and verifying association with inflammatory biomarkers. It was a cross-sectional study with 391 adolescents aged 17 and 18 from public schools in São Luís-MA. Were build latent variables “Socioeconomic Conditions” (SES) and “inflammation”, consisting of the biomarkers interleukin-1β, interleukin-6 and interleukin-8. Dietary patterns were identified by factor analysis by main components. Modeling of structural equations to assess factors associated with inflammatory biomarkers. Three PAs were extracted (western, basic Brazilian and healthy). Not found association between PAS and “inflammation”. However, excess weight was positively associated with “inflammation” (CP = 0.281; p = 0.002). The second article objective to evaluate the relative validity of the Food Frequency Questionnaire (FFQ) used in the RPS Cohort to assess food intake of adolescents in São Luís- BAD. Study developed with 152 adolescents aged 17 and 18 years old. To the validation of the FFQ, the average of three 24-hour recalls (R24h) was used as reference method. The paired t-Student test was used to verify differences between the instruments. To measure concordance, coefficients of Pearson correlation, intraclass correlation coefficient (ICC), weighted Kappa and Bland-Altman graphics. Significance level <5% was adopted. When compared with R24h, the FFQ evaluated overestimated the consumption of most nutrients. You Pearson's correlation coefficients after adjustment for energy consumption and attenuation ranged from 0.06 - 0.43 and, despite the weak / moderate correlation, were significant for the nutrients iron, calcium, riboflavin, sodium, saturated fatty acids, niacin and vitamin C. Adjusted and diluted intraclass correlation coefficients (ICC) varied from 0.01 - 0.31 and the weighted kappa of the energy-adjusted variables ranged from 0.01 - 0.46. Agreement analyzes were significant for Vitamin C, fiber, calcium, riboflavin, niacin and sodium, lipids and iron. This FFQ was relatively valid acceptable for lipid nutrients, saturated fatty acids, fibers, calcium, iron, riboflavin, niacin, vitamin C and sodium. The third article aimed to identify adolescents' PAs and assess factors associated with inflammatory biomarkers, through a cross-sectional study aligned with the RPS cohort, with data from São Luís-MA. 511 adolescents aged 18 and 19 years were evaluated. PAs were identified by factor analysis by main components. To assess nutritional status, we used Body Mass Index (BMI) and body fat percentage (% BF), assessed by the air displacement plethysmography method. Modeling was done hierarchized using Linear Regression to estimate the Beta coefficient (β) of independent variables with the dependent variables, Interleukin-6 (IL-6) and Ultra-sensitive C-reactive protein (hs-CRP). Five dietary patterns were identified: energy-dense, sugary drinks and breakfast cereals, prudent, common Brazilian and alcoholic and energy drinks. The “prudent” pattern pointed to the association with the subclinical inflammation assessed using IL-6, this pattern being considered a protective factor for inflammation (β = -0.11; p value = 0.040). PAs “Common Brazilian” and “alcoholic and energy drinks” were indirectly associated the increase in IL-6, mediated by nutritional status. CRP levels were directly associated with BMI (β = 0.36; p value = <0.001) and% BG (β = 0.02; p value = 0.014). Subclinical inflammation was associated with nutritional status and prudent BP, in which adolescents with higher BMI and% BF had higher concentrations of CRP-us and those with greater adherence to prudent AP had lower concentrations of IL-6, thus being a protector of subclinical inflammation.As práticas alimentares representam um dos principais componentes do estilo de vida a favorecer o desenvolvimento da obesidade e suas comorbidades e disfunções metabólicas importantes que desencadeiam o processo inflamatório. O primeiro artigo desta tese objetivou identificar os principais padrões alimentares (PAs) de adolescentes e verificar associação com biomarcadores inflamatórios. Tratou-se de estudo transversal com 391 adolescentes de 17 e 18 anos de escolas públicas em São Luís-MA. Foram construídas variáveis latentes “Condições Socioeconômicas” (SES) e “inflamação”, constituída pelos biomarcadores interleucina-1β, interleucina-6 e interleucina-8. Padrões alimentares foram identificados por análise fatorial por componentes principais. Foi utilizada modelagem de equações estruturais para avaliar fatores associados aos biomarcadores inflamatórios. Foram extraídos três PAs (ocidental, básico brasileiro e saudável). Não foi encontrada associação entre PAS e “inflamação”. Porém, o excesso de peso foi positivamente associado com a “inflamação” (CP = 0,281; p=0,002). O segundo artigo teve como objetivo avaliar a validade relativa do Questionário de Frequência Alimentar (QFA) utilizado na Coorte RPS para avaliar consumo alimentar de adolescentes em São Luís- MA. Estudo desenvolvido com 152 adolescentes com 17 e 18 anos de idade. Para a validação do QFA, utilizou-se a média de três recordatório de 24 horas (R24h) como método de referência. O teste t-Student pareado foi utilizado para verificar diferenças entre os instrumentos. Para medir concordância foram calculados coeficientes de correlação de Pearson, coeficiente de correlação intraclasse (CCI), Kappa ponderado e gráficos de Bland-Altman. Adotou-se nível de significância <5%. Quando comparado com o R24h, o QFA avaliado superestimou o consumo da maioria dos nutrientes. Os coeficientes de correlação de Pearson após ajuste para consumo de energia e deatenuação variaram de 0,06 - 0,43 e, apesar da fraca/moderada correlação, foram significativos para os nutrientes ferro, cálcio, riboflavina, sódio, ácidos graxos saturados, niacina e vitamina C. Os Coeficientes de Correlação Intraclasse (CCI) ajustados e deatenuados variaram de 0,01 - 0,31 e o kappa ponderado das variáveis ajustadas para energia variaram de 0,01 - 0,46. As análises de concordâncias foram significantes para a Vitamina C, fibra, cálcio, riboflavina, niacina e sódio, lipídeos e ferro. Este QFA apresentou validade relativa aceitável para os nutrientes lipídeos, ácidos graxos saturados, fibras, cálcio, ferro, riboflavina, niacina, vitamina C e sódio. O terceiro artigo teve como objetivo identificar os PAs dos adolescentes e avaliar os fatores associados aos biomarcadores inflamatórios, por meio um estudo transversal alinhado à coorte RPS, com os dados São Luís-MA. Foram avaliados 511 adolescentes de 18 e 19 anos. Os PAs foram identificados por análise fatorial por componentes principais. Para avaliação do estado nutricional utilizouse Índice de Massa Corporal (IMC) e percentual de gordura corporal (%GC), avaliado pelo método de pletismografia por deslocamento de ar. Foi feita modelagem hierarquizada por meio de Regressão Linear para estimar o coeficiente Beta (β) das variáveis independentes com as variáveis dependentes, a Interleucina-6 (IL-6) e a Proteína C-Reativa ultrassensível (PCR-us). Cinco padrões alimentares foram identificados: denso em energia, bebidas açucaradas e cereais matinais, prudente, comum brasileiro e bebidas alcoólicas e energéticas. O padrão “prudente” apontou a associação direta com a inflamação subclínica avaliada por meio da IL-6, sendo este padrão considerado fator de proteção para a inflamação (β=-0,11; p valor = 0,040). Os PAs “comum brasileiro” e “bebidas alcóolicas e energéticas” foram indiretamente associados ao aumento da IL-6, mediados pelo estado nutricional. Os níveis de PCR-us foram diretamente associados com IMC (β = 0,36; p valor = <0,001) e %GC (β= 0,02; p valor = 0,014). A inflamação subclínica foi associada com estado nutricional e com PA prudente, em que os adolescentes com maiores IMC e %GC tiveram maiores concentrações de PCR-us e aqueles com maior aderência ao PA prudente tiveram menores concentrações de IL-6, sendo então um protetor da inflamação subclínica.Submitted by Sheila MONTEIRO (sheila.monteiro@ufma.br) on 2021-02-17T15:14:56Z No. of bitstreams: 1 EDUARDA-GOMES.pdf: 6369213 bytes, checksum: 7ec6f13df89fb160b7ddc68b927c8615 (MD5)Made available in DSpace on 2021-02-17T15:14:56Z (GMT). No. of bitstreams: 1 EDUARDA-GOMES.pdf: 6369213 bytes, checksum: 7ec6f13df89fb160b7ddc68b927c8615 (MD5) Previous issue date: 2019-11-26Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão - FAPEMAConselho Nacional de Desenvolvimento Científico e Tecnológico - CNPqFundação de Amparo à Pesquisa do Estado de São Paulo - FASESPapplication/pdfporUniversidade Federal do MaranhãoPROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE COLETIVA/CCBSUFMABrasilDEPARTAMENTO DE CIÊNCIAS FISIOLÓGICAS/CCBSConsumo alimentarEstudos de ValidaçãoAdolescenteEstado NutricionalInflamaçãoFood consumptionValidation StudiesAdolescentState NutritionalInflammationCiências da SaúdeValidade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentesRelative validity of a food frequency questionnaire, dietary patterns and factors associated with inflammatory biomarkers in adolescentsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFMAinstname:Universidade Federal do Maranhão (UFMA)instacron:UFMAORIGINALEDUARDA-GOMES.pdfEDUARDA-GOMES.pdfapplication/pdf6369213http://tedebc.ufma.br:8080/bitstream/tede/3194/2/EDUARDA-GOMES.pdf7ec6f13df89fb160b7ddc68b927c8615MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82255http://tedebc.ufma.br:8080/bitstream/tede/3194/1/license.txt97eeade1fce43278e63fe063657f8083MD51tede/31942021-02-17 12:14:56.496oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttps://tedebc.ufma.br/jspui/PUBhttp://tedebc.ufma.br:8080/oai/requestrepositorio@ufma.br||repositorio@ufma.bropendoar:21312021-02-17T15:14:56Biblioteca Digital de Teses e Dissertações da UFMA - Universidade Federal do Maranhão (UFMA)false |
dc.title.por.fl_str_mv |
Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes |
dc.title.alternative.eng.fl_str_mv |
Relative validity of a food frequency questionnaire, dietary patterns and factors associated with inflammatory biomarkers in adolescents |
title |
Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes |
spellingShingle |
Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes BOGEA, Eduarda Gomes Consumo alimentar Estudos de Validação Adolescente Estado Nutricional Inflamação Food consumption Validation Studies Adolescent State Nutritional Inflammation Ciências da Saúde |
title_short |
Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes |
title_full |
Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes |
title_fullStr |
Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes |
title_full_unstemmed |
Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes |
title_sort |
Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes |
author |
BOGEA, Eduarda Gomes |
author_facet |
BOGEA, Eduarda Gomes |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
FRANÇA, Ana Karina Teixeira da Cunha |
dc.contributor.advisor1ID.fl_str_mv |
880995124-72 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/8389486900285691 |
dc.contributor.advisor-co1.fl_str_mv |
SILVA, Antônio Augusto Moura da |
dc.contributor.advisor-co1ID.fl_str_mv |
176754643-20 |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/8652081312944025 |
dc.contributor.referee1.fl_str_mv |
FRANÇA, Ana Karina Teixeira da Cunha |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/8389486900285691 |
dc.contributor.referee2.fl_str_mv |
SILVA, Antônio Augusto Moura da |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/8652081312944025 |
dc.contributor.referee3.fl_str_mv |
RIBEIRO, Cecília Claudia Costa |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/1783658679814263 |
dc.contributor.referee4.fl_str_mv |
NASCIMENTO, Joelma Ximenes Prado Teixeira |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/9553463144721017 |
dc.contributor.referee5.fl_str_mv |
MACHADO, Soraia Pinheiro |
dc.contributor.referee5Lattes.fl_str_mv |
http://lattes.cnpq.br/9623777040675359 |
dc.contributor.authorID.fl_str_mv |
045209623-58 |
dc.contributor.author.fl_str_mv |
BOGEA, Eduarda Gomes |
contributor_str_mv |
FRANÇA, Ana Karina Teixeira da Cunha SILVA, Antônio Augusto Moura da FRANÇA, Ana Karina Teixeira da Cunha SILVA, Antônio Augusto Moura da RIBEIRO, Cecília Claudia Costa NASCIMENTO, Joelma Ximenes Prado Teixeira MACHADO, Soraia Pinheiro |
dc.subject.por.fl_str_mv |
Consumo alimentar Estudos de Validação Adolescente Estado Nutricional Inflamação |
topic |
Consumo alimentar Estudos de Validação Adolescente Estado Nutricional Inflamação Food consumption Validation Studies Adolescent State Nutritional Inflammation Ciências da Saúde |
dc.subject.eng.fl_str_mv |
Food consumption Validation Studies Adolescent State Nutritional Inflammation |
dc.subject.cnpq.fl_str_mv |
Ciências da Saúde |
description |
Eating practices represent one of the main components of the lifestyle to be favor the development of obesity and its comorbidities and metabolic disorders important factors that trigger the inflammatory process. The first article of this thesis aimed at identifying the main dietary patterns (BPs) of adolescents and verifying association with inflammatory biomarkers. It was a cross-sectional study with 391 adolescents aged 17 and 18 from public schools in São Luís-MA. Were build latent variables “Socioeconomic Conditions” (SES) and “inflammation”, consisting of the biomarkers interleukin-1β, interleukin-6 and interleukin-8. Dietary patterns were identified by factor analysis by main components. Modeling of structural equations to assess factors associated with inflammatory biomarkers. Three PAs were extracted (western, basic Brazilian and healthy). Not found association between PAS and “inflammation”. However, excess weight was positively associated with “inflammation” (CP = 0.281; p = 0.002). The second article objective to evaluate the relative validity of the Food Frequency Questionnaire (FFQ) used in the RPS Cohort to assess food intake of adolescents in São Luís- BAD. Study developed with 152 adolescents aged 17 and 18 years old. To the validation of the FFQ, the average of three 24-hour recalls (R24h) was used as reference method. The paired t-Student test was used to verify differences between the instruments. To measure concordance, coefficients of Pearson correlation, intraclass correlation coefficient (ICC), weighted Kappa and Bland-Altman graphics. Significance level <5% was adopted. When compared with R24h, the FFQ evaluated overestimated the consumption of most nutrients. You Pearson's correlation coefficients after adjustment for energy consumption and attenuation ranged from 0.06 - 0.43 and, despite the weak / moderate correlation, were significant for the nutrients iron, calcium, riboflavin, sodium, saturated fatty acids, niacin and vitamin C. Adjusted and diluted intraclass correlation coefficients (ICC) varied from 0.01 - 0.31 and the weighted kappa of the energy-adjusted variables ranged from 0.01 - 0.46. Agreement analyzes were significant for Vitamin C, fiber, calcium, riboflavin, niacin and sodium, lipids and iron. This FFQ was relatively valid acceptable for lipid nutrients, saturated fatty acids, fibers, calcium, iron, riboflavin, niacin, vitamin C and sodium. The third article aimed to identify adolescents' PAs and assess factors associated with inflammatory biomarkers, through a cross-sectional study aligned with the RPS cohort, with data from São Luís-MA. 511 adolescents aged 18 and 19 years were evaluated. PAs were identified by factor analysis by main components. To assess nutritional status, we used Body Mass Index (BMI) and body fat percentage (% BF), assessed by the air displacement plethysmography method. Modeling was done hierarchized using Linear Regression to estimate the Beta coefficient (β) of independent variables with the dependent variables, Interleukin-6 (IL-6) and Ultra-sensitive C-reactive protein (hs-CRP). Five dietary patterns were identified: energy-dense, sugary drinks and breakfast cereals, prudent, common Brazilian and alcoholic and energy drinks. The “prudent” pattern pointed to the association with the subclinical inflammation assessed using IL-6, this pattern being considered a protective factor for inflammation (β = -0.11; p value = 0.040). PAs “Common Brazilian” and “alcoholic and energy drinks” were indirectly associated the increase in IL-6, mediated by nutritional status. CRP levels were directly associated with BMI (β = 0.36; p value = <0.001) and% BG (β = 0.02; p value = 0.014). Subclinical inflammation was associated with nutritional status and prudent BP, in which adolescents with higher BMI and% BF had higher concentrations of CRP-us and those with greater adherence to prudent AP had lower concentrations of IL-6, thus being a protector of subclinical inflammation. |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019-11-26 |
dc.date.accessioned.fl_str_mv |
2021-02-17T15:14:56Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BOGEA, Eduarda Gomes. Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes. 2019. 200 f. Tese (Programa de Pós-Graduação em Saúde Coletiva/CCBS) - Universidade Federal do Maranhão, São Luís, 2019. |
dc.identifier.uri.fl_str_mv |
https://tedebc.ufma.br/jspui/handle/tede/tede/3194 |
identifier_str_mv |
BOGEA, Eduarda Gomes. Validade relativa de um questionário de frequência alimentar, padrões alimentares e fatores associados à biomarcadores inflamatórios em adolescentes. 2019. 200 f. Tese (Programa de Pós-Graduação em Saúde Coletiva/CCBS) - Universidade Federal do Maranhão, São Luís, 2019. |
url |
https://tedebc.ufma.br/jspui/handle/tede/tede/3194 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal do Maranhão |
dc.publisher.program.fl_str_mv |
PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE COLETIVA/CCBS |
dc.publisher.initials.fl_str_mv |
UFMA |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
DEPARTAMENTO DE CIÊNCIAS FISIOLÓGICAS/CCBS |
publisher.none.fl_str_mv |
Universidade Federal do Maranhão |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da UFMA instname:Universidade Federal do Maranhão (UFMA) instacron:UFMA |
instname_str |
Universidade Federal do Maranhão (UFMA) |
instacron_str |
UFMA |
institution |
UFMA |
reponame_str |
Biblioteca Digital de Teses e Dissertações da UFMA |
collection |
Biblioteca Digital de Teses e Dissertações da UFMA |
bitstream.url.fl_str_mv |
http://tedebc.ufma.br:8080/bitstream/tede/3194/2/EDUARDA-GOMES.pdf http://tedebc.ufma.br:8080/bitstream/tede/3194/1/license.txt |
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MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações da UFMA - Universidade Federal do Maranhão (UFMA) |
repository.mail.fl_str_mv |
repositorio@ufma.br||repositorio@ufma.br |
_version_ |
1800303801097256960 |