Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section

Detalhes bibliográficos
Autor(a) principal: Bovino,F.
Data de Publicação: 2019
Outros Autores: Denadai,D.S., Ávila,L.G., Deschk,M., Santos,P.S.P., Feitosa,F.L.F., Peiró,J.R., Mendes,L.C.N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100044
Resumo: ABSTRACT The aim of this study was to assess the vitality and lung function of preterm lambs. Twenty seven preterm lambs were divided in four groups. Group I (n=6) preterm lambs/ control; group II (n=9) lambs born to mothers that were treated with dexamethasone antepartum; group III (n=6) lambs treated with surfactant; and group IV (n=6) lambs treated with surfactant and born to mothers that were treated with dexamethasone antepartum. The APGAR score was performed after birth (T0) and 15 minutes later (T1/4) to assess vitality. The vital signs, blood gas analysis, spirometry and capnometry were assessed immediately after birth and continued until 48 hours. Chest radiographs were performed at T0, T24 and T48. Significant rectal temperature interactions occurred at T1 and T6 depending on the type of treatment used. All animals showed low pH values, which were associated with high pCO2 values and HCO3 -values that increased over time from immediately after birth to two days of age. Higher tidal volume values were observed at T1/4, T1 and T24 when the animals were not treated with surfactant. Capnometry showed significant interactions between treatments at T0. Premature animals showed low vitality and impaired pulmonary function.
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spelling Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean sectionlambsneonatologyvitalityvital parametersABSTRACT The aim of this study was to assess the vitality and lung function of preterm lambs. Twenty seven preterm lambs were divided in four groups. Group I (n=6) preterm lambs/ control; group II (n=9) lambs born to mothers that were treated with dexamethasone antepartum; group III (n=6) lambs treated with surfactant; and group IV (n=6) lambs treated with surfactant and born to mothers that were treated with dexamethasone antepartum. The APGAR score was performed after birth (T0) and 15 minutes later (T1/4) to assess vitality. The vital signs, blood gas analysis, spirometry and capnometry were assessed immediately after birth and continued until 48 hours. Chest radiographs were performed at T0, T24 and T48. Significant rectal temperature interactions occurred at T1 and T6 depending on the type of treatment used. All animals showed low pH values, which were associated with high pCO2 values and HCO3 -values that increased over time from immediately after birth to two days of age. Higher tidal volume values were observed at T1/4, T1 and T24 when the animals were not treated with surfactant. Capnometry showed significant interactions between treatments at T0. Premature animals showed low vitality and impaired pulmonary function.Universidade Federal de Minas Gerais, Escola de Veterinária2019-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100044Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.71 n.1 2019reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/1678-4162-10390info:eu-repo/semantics/openAccessBovino,F.Denadai,D.S.Ávila,L.G.Deschk,M.Santos,P.S.P.Feitosa,F.L.F.Peiró,J.R.Mendes,L.C.N.eng2019-03-25T00:00:00Zoai:scielo:S0102-09352019000100044Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2019-03-25T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section
title Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section
spellingShingle Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section
Bovino,F.
lambs
neonatology
vitality
vital parameters
title_short Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section
title_full Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section
title_fullStr Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section
title_full_unstemmed Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section
title_sort Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section
author Bovino,F.
author_facet Bovino,F.
Denadai,D.S.
Ávila,L.G.
Deschk,M.
Santos,P.S.P.
Feitosa,F.L.F.
Peiró,J.R.
Mendes,L.C.N.
author_role author
author2 Denadai,D.S.
Ávila,L.G.
Deschk,M.
Santos,P.S.P.
Feitosa,F.L.F.
Peiró,J.R.
Mendes,L.C.N.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bovino,F.
Denadai,D.S.
Ávila,L.G.
Deschk,M.
Santos,P.S.P.
Feitosa,F.L.F.
Peiró,J.R.
Mendes,L.C.N.
dc.subject.por.fl_str_mv lambs
neonatology
vitality
vital parameters
topic lambs
neonatology
vitality
vital parameters
description ABSTRACT The aim of this study was to assess the vitality and lung function of preterm lambs. Twenty seven preterm lambs were divided in four groups. Group I (n=6) preterm lambs/ control; group II (n=9) lambs born to mothers that were treated with dexamethasone antepartum; group III (n=6) lambs treated with surfactant; and group IV (n=6) lambs treated with surfactant and born to mothers that were treated with dexamethasone antepartum. The APGAR score was performed after birth (T0) and 15 minutes later (T1/4) to assess vitality. The vital signs, blood gas analysis, spirometry and capnometry were assessed immediately after birth and continued until 48 hours. Chest radiographs were performed at T0, T24 and T48. Significant rectal temperature interactions occurred at T1 and T6 depending on the type of treatment used. All animals showed low pH values, which were associated with high pCO2 values and HCO3 -values that increased over time from immediately after birth to two days of age. Higher tidal volume values were observed at T1/4, T1 and T24 when the animals were not treated with surfactant. Capnometry showed significant interactions between treatments at T0. Premature animals showed low vitality and impaired pulmonary function.
publishDate 2019
dc.date.none.fl_str_mv 2019-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100044
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100044
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4162-10390
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.71 n.1 2019
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
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