Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus

Detalhes bibliográficos
Autor(a) principal: Alves,C.M.
Data de Publicação: 2006
Outros Autores: Vasconcelos,A.C., Martins,A.S., del Puerto,H.L., Santos,F.G.A., Nunes,J.E.S., Campos,P.P., Moro,L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000400004
Resumo: The thymic morphometry analysis was used for determining apoptosis and atrophy of the thymus of eight puppies inoculated with canine distemper virus (CDV). Three healthy dogs were used as negative controls. Sections, 5µm thick, were stained by HE and Shorr, and the latter were evaluated by morphometry. CDV nucleoprotein was detected by immunohistochemistry. Morphometric results confirmed lymphoid hypotrophy in CDV inoculated dog thymuses, more stroma, less parenchyma and higher apoptotic index/field than negative control (not inoculated) puppies. Apoptosis plays a role in the mechanism of thymus atrophy that develops in canine distemper.
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spelling Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper viruspuppyapoptosisthymuscanine distemperimmunologyvirusimmunosuppressionThe thymic morphometry analysis was used for determining apoptosis and atrophy of the thymus of eight puppies inoculated with canine distemper virus (CDV). Three healthy dogs were used as negative controls. Sections, 5µm thick, were stained by HE and Shorr, and the latter were evaluated by morphometry. CDV nucleoprotein was detected by immunohistochemistry. Morphometric results confirmed lymphoid hypotrophy in CDV inoculated dog thymuses, more stroma, less parenchyma and higher apoptotic index/field than negative control (not inoculated) puppies. Apoptosis plays a role in the mechanism of thymus atrophy that develops in canine distemper.Universidade Federal de Minas Gerais, Escola de Veterinária2006-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000400004Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.58 n.4 2006reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352006000400004info:eu-repo/semantics/openAccessAlves,C.M.Vasconcelos,A.C.Martins,A.S.del Puerto,H.L.Santos,F.G.A.Nunes,J.E.S.Campos,P.P.Moro,L.eng2006-10-06T00:00:00Zoai:scielo:S0102-09352006000400004Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2006-10-06T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus
title Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus
spellingShingle Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus
Alves,C.M.
puppy
apoptosis
thymus
canine distemper
immunology
virus
immunosuppression
title_short Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus
title_full Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus
title_fullStr Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus
title_full_unstemmed Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus
title_sort Morphometric analysis of the thymus of puppies infected with the Snyder Hill Strain of canine distemper virus
author Alves,C.M.
author_facet Alves,C.M.
Vasconcelos,A.C.
Martins,A.S.
del Puerto,H.L.
Santos,F.G.A.
Nunes,J.E.S.
Campos,P.P.
Moro,L.
author_role author
author2 Vasconcelos,A.C.
Martins,A.S.
del Puerto,H.L.
Santos,F.G.A.
Nunes,J.E.S.
Campos,P.P.
Moro,L.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Alves,C.M.
Vasconcelos,A.C.
Martins,A.S.
del Puerto,H.L.
Santos,F.G.A.
Nunes,J.E.S.
Campos,P.P.
Moro,L.
dc.subject.por.fl_str_mv puppy
apoptosis
thymus
canine distemper
immunology
virus
immunosuppression
topic puppy
apoptosis
thymus
canine distemper
immunology
virus
immunosuppression
description The thymic morphometry analysis was used for determining apoptosis and atrophy of the thymus of eight puppies inoculated with canine distemper virus (CDV). Three healthy dogs were used as negative controls. Sections, 5µm thick, were stained by HE and Shorr, and the latter were evaluated by morphometry. CDV nucleoprotein was detected by immunohistochemistry. Morphometric results confirmed lymphoid hypotrophy in CDV inoculated dog thymuses, more stroma, less parenchyma and higher apoptotic index/field than negative control (not inoculated) puppies. Apoptosis plays a role in the mechanism of thymus atrophy that develops in canine distemper.
publishDate 2006
dc.date.none.fl_str_mv 2006-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000400004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000400004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-09352006000400004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.58 n.4 2006
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
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