Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma

Detalhes bibliográficos
Autor(a) principal: Lessa,D.A.B.
Data de Publicação: 2019
Outros Autores: Alencar,N.X., Torres Filho,R.A., Costa,M.F.M., Fernandes,W.R., Saraiva,E.M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300939
Resumo: ABSTRACT Alveolar macrophages (AMs) are an essential part of defense mechanisms within the lungs and their phagocytic activity is important for organ homeostasis. The phagocytic ability of AMs obtained from bronchoalveolar lavage from 17 mature mixed-breed pleasure horses (8 healthy and 9 diagnosed with mild equine asthma) was studied through assays with Leishmania (Viannia) braziliensis promastigotes, which enabled the calculation of a phagocytic index (PI) and a survival index (SI). Results indicate that phagocytic activity of AMs in asthma affected horses is similar to healthy horses, while leishmanicidal activity is significantly increased in horses with asthma.
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spelling Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthmahorsesequine asthmaalveolar macrophagephagocytosisLeishmania (Viannia) braziliensisABSTRACT Alveolar macrophages (AMs) are an essential part of defense mechanisms within the lungs and their phagocytic activity is important for organ homeostasis. The phagocytic ability of AMs obtained from bronchoalveolar lavage from 17 mature mixed-breed pleasure horses (8 healthy and 9 diagnosed with mild equine asthma) was studied through assays with Leishmania (Viannia) braziliensis promastigotes, which enabled the calculation of a phagocytic index (PI) and a survival index (SI). Results indicate that phagocytic activity of AMs in asthma affected horses is similar to healthy horses, while leishmanicidal activity is significantly increased in horses with asthma.Universidade Federal de Minas Gerais, Escola de Veterinária2019-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300939Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.71 n.3 2019reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/1678-4162-10708info:eu-repo/semantics/openAccessLessa,D.A.B.Alencar,N.X.Torres Filho,R.A.Costa,M.F.M.Fernandes,W.R.Saraiva,E.M.eng2019-07-02T00:00:00Zoai:scielo:S0102-09352019000300939Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2019-07-02T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
title Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
spellingShingle Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
Lessa,D.A.B.
horses
equine asthma
alveolar macrophage
phagocytosis
Leishmania (Viannia) braziliensis
title_short Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
title_full Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
title_fullStr Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
title_full_unstemmed Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
title_sort Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
author Lessa,D.A.B.
author_facet Lessa,D.A.B.
Alencar,N.X.
Torres Filho,R.A.
Costa,M.F.M.
Fernandes,W.R.
Saraiva,E.M.
author_role author
author2 Alencar,N.X.
Torres Filho,R.A.
Costa,M.F.M.
Fernandes,W.R.
Saraiva,E.M.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lessa,D.A.B.
Alencar,N.X.
Torres Filho,R.A.
Costa,M.F.M.
Fernandes,W.R.
Saraiva,E.M.
dc.subject.por.fl_str_mv horses
equine asthma
alveolar macrophage
phagocytosis
Leishmania (Viannia) braziliensis
topic horses
equine asthma
alveolar macrophage
phagocytosis
Leishmania (Viannia) braziliensis
description ABSTRACT Alveolar macrophages (AMs) are an essential part of defense mechanisms within the lungs and their phagocytic activity is important for organ homeostasis. The phagocytic ability of AMs obtained from bronchoalveolar lavage from 17 mature mixed-breed pleasure horses (8 healthy and 9 diagnosed with mild equine asthma) was studied through assays with Leishmania (Viannia) braziliensis promastigotes, which enabled the calculation of a phagocytic index (PI) and a survival index (SI). Results indicate that phagocytic activity of AMs in asthma affected horses is similar to healthy horses, while leishmanicidal activity is significantly increased in horses with asthma.
publishDate 2019
dc.date.none.fl_str_mv 2019-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300939
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300939
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4162-10708
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.71 n.3 2019
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
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