Model of induction of thyroid dysfunctions in adult female mice

Detalhes bibliográficos
Autor(a) principal: Ferreira,E.
Data de Publicação: 2007
Outros Autores: Silva,A.E., Serakides,R., Gomes,A.E.S., Cassali,G.D.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000500022
Resumo: It is described the elaboration of a protocol to induce hyperthyroidism and hypothyroidism in mice by administrating thyroxin and propylthiouracil, respectively, in the drinking water. The drugs were administered to adult female mice of the Swiss strain for 30 days in order to obtain a systemic status of thyroid dysfunction. The induction of hyperthyroidism and hypothyroidism in the animals was confirmed by the histomorphological analysis of the thyroid in the end of the experiment, when the state of gland dysfunction in the animals submitted to the treatment was observed.
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spelling Model of induction of thyroid dysfunctions in adult female micemousethyroidprotocolinductionthyroxinpropylthiouracilIt is described the elaboration of a protocol to induce hyperthyroidism and hypothyroidism in mice by administrating thyroxin and propylthiouracil, respectively, in the drinking water. The drugs were administered to adult female mice of the Swiss strain for 30 days in order to obtain a systemic status of thyroid dysfunction. The induction of hyperthyroidism and hypothyroidism in the animals was confirmed by the histomorphological analysis of the thyroid in the end of the experiment, when the state of gland dysfunction in the animals submitted to the treatment was observed.Universidade Federal de Minas Gerais, Escola de Veterinária2007-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000500022Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.59 n.5 2007reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352007000500022info:eu-repo/semantics/openAccessFerreira,E.Silva,A.E.Serakides,R.Gomes,A.E.S.Cassali,G.D.eng2007-12-19T00:00:00Zoai:scielo:S0102-09352007000500022Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2007-12-19T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Model of induction of thyroid dysfunctions in adult female mice
title Model of induction of thyroid dysfunctions in adult female mice
spellingShingle Model of induction of thyroid dysfunctions in adult female mice
Ferreira,E.
mouse
thyroid
protocol
induction
thyroxin
propylthiouracil
title_short Model of induction of thyroid dysfunctions in adult female mice
title_full Model of induction of thyroid dysfunctions in adult female mice
title_fullStr Model of induction of thyroid dysfunctions in adult female mice
title_full_unstemmed Model of induction of thyroid dysfunctions in adult female mice
title_sort Model of induction of thyroid dysfunctions in adult female mice
author Ferreira,E.
author_facet Ferreira,E.
Silva,A.E.
Serakides,R.
Gomes,A.E.S.
Cassali,G.D.
author_role author
author2 Silva,A.E.
Serakides,R.
Gomes,A.E.S.
Cassali,G.D.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Ferreira,E.
Silva,A.E.
Serakides,R.
Gomes,A.E.S.
Cassali,G.D.
dc.subject.por.fl_str_mv mouse
thyroid
protocol
induction
thyroxin
propylthiouracil
topic mouse
thyroid
protocol
induction
thyroxin
propylthiouracil
description It is described the elaboration of a protocol to induce hyperthyroidism and hypothyroidism in mice by administrating thyroxin and propylthiouracil, respectively, in the drinking water. The drugs were administered to adult female mice of the Swiss strain for 30 days in order to obtain a systemic status of thyroid dysfunction. The induction of hyperthyroidism and hypothyroidism in the animals was confirmed by the histomorphological analysis of the thyroid in the end of the experiment, when the state of gland dysfunction in the animals submitted to the treatment was observed.
publishDate 2007
dc.date.none.fl_str_mv 2007-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000500022
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000500022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-09352007000500022
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.59 n.5 2007
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
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