Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | https://doi.org/10.1016/S0140-6736(18)31310-2 http://hdl.handle.net/1843/52085 https://orcid.org/0000-0002-8214-5734 |
Resumo: | Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks perweek.Interpretation. Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that therisk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption. |
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Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016Alcohol AbuseGlobal Burden of DiseaseAlcoolismoCarga Global da DoençaBackground Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks perweek.Interpretation. Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that therisk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption.Universidade Federal de Minas GeraisBrasilENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICAENF - DEPARTAMENTO DE NUTRIÇÃOUFMG2023-04-17T21:04:15Z2023-04-17T21:04:15Z2018info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlepdfapplication/pdfhttps://doi.org/10.1016/S0140-6736(18)31310-201406736http://hdl.handle.net/1843/52085https://orcid.org/0000-0002-8214-5734engThe LancetMariana Santos Felisbino-mendesEduarda FernandesAlize j FerrariCleusa p FerriDaniel Obadare FijabiZegeye AbebeIrina FilipJonas David FingerFlorian FischerAbraham d FlaxmanRichard Charles FranklinCatalina Liliana AndreiEngida YismaNaohiro YonemotoSeok-jun YoonMarcel YotebiengZiyad Al-alyMustafa z YounisGeevar ZachariahNima Hafezi-nejadAndre m n RenzahoAdauto Martins Soares FilhoArjun Lakshmana BalajiZoubida ZaidiMohammad ZamaniXueying ZhangSanjay ZodpeyColin AngusAli h MokdadVinay NangiaMohsen NaghaviChristopher j l MurrayMoslem SoofiMika KivimäkiEmmanuela GakidouMustafa Geleto AnshaRatilal LallooTekleberhan Beyene HagosCarl Abelardo t AntonioOlatunde AremuJohan Ärnlöval ArtamanJobert Richie NansseuReed j d SorensenKrishna k AryalKarzan Abdulmuhsin MohammadReza AssadiMarcel AusloosHayley d TymesonLeticia Avila-burgosTea LallukkaEuripide f AvokpahoGessessew Bugssa HailuAshish AwasthiJoan b SorianoHenok Tadesse AyeleMudavath Siva Durga Prasad NayakMohammad Sadegh RezaiRakesh AyerTambe b AyukPeter s AzzopardiHamid BadaliAlaa BadawiMaciej BanachHilton LamChandrashekhar t SreeramareddyVidhya VenkateswaranSuzanne Lyn Barker-colloRandah r HamadehLeonardo RoeverChakib NejjariLope h BarreroHuda BasaleemEstifanos BayeShahrzad Bazargan-hejaziNeeraj BediBarthelemy Kuate DefoYannick BéjotAbate Bekele BelachewFaris Hasan LamiSaba Abraham BelayLuca RonfaniDerrick a BennettSubas NeupaneAustin Douglas TappSamer HamidiIsabela m 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dc.title.none.fl_str_mv |
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016 |
title |
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016 |
spellingShingle |
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016 Mariana Santos Felisbino-mendes Alcohol Abuse Global Burden of Disease Alcoolismo Carga Global da Doença |
title_short |
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016 |
title_full |
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016 |
title_fullStr |
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016 |
title_full_unstemmed |
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016 |
title_sort |
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016 |
author |
Mariana Santos Felisbino-mendes |
author_facet |
Mariana Santos Felisbino-mendes Eduarda Fernandes Alize j Ferrari Cleusa p Ferri Daniel Obadare Fijabi Zegeye Abebe Irina Filip Jonas David Finger Florian Fischer Abraham d Flaxman Richard Charles Franklin Catalina Liliana Andrei Engida Yisma Naohiro Yonemoto Seok-jun Yoon Marcel Yotebieng Ziyad Al-aly Mustafa z Younis Geevar Zachariah Nima Hafezi-nejad Andre m n Renzaho Adauto Martins Soares Filho Arjun Lakshmana Balaji Zoubida Zaidi Mohammad Zamani Xueying Zhang Sanjay Zodpey Colin Angus Ali h Mokdad Vinay Nangia Mohsen Naghavi Christopher j l Murray Moslem Soofi Mika Kivimäki Emmanuela Gakidou Mustafa Geleto Ansha Ratilal Lalloo Tekleberhan Beyene Hagos Carl Abelardo t Antonio Olatunde Aremu Johan Ärnlöv al Artaman Jobert Richie Nansseu Reed j d Sorensen Krishna k Aryal Karzan Abdulmuhsin Mohammad Reza Assadi Marcel Ausloos Hayley d Tymeson Leticia Avila-burgos Tea Lallukka Euripide f Avokpaho Gessessew Bugssa Hailu Ashish Awasthi Joan b Soriano Henok Tadesse Ayele Mudavath Siva Durga Prasad Nayak Mohammad Sadegh Rezai Rakesh Ayer Tambe b Ayuk Peter s Azzopardi Hamid Badali Alaa Badawi Maciej Banach Hilton Lam Chandrashekhar t Sreeramareddy Vidhya Venkateswaran Suzanne Lyn Barker-collo Randah r Hamadeh Leonardo Roever Chakib Nejjari Lope h Barrero Huda Basaleem Estifanos Baye Shahrzad Bazargan-hejazi Neeraj Bedi Barthelemy Kuate Defo Yannick Béjot Abate Bekele Belachew Faris Hasan Lami Saba Abraham Belay Luca Ronfani Derrick a Bennett Subas Neupane Austin Douglas Tapp Samer Hamidi Isabela m Bensenor Azmeraw t Amare Eduardo Bernabe Robert s Bernstein Addisu Shunu Beyene Tina Beyranvand Soumyadeeep Bhaumik Robin Room Qing Lan Zulfiqar a Bhutta Jagdish Khubchandani Belete Biadgo Nadine Steckling Ali Bijani Nigus Bililign Graeme j Hankey Mohammad h Forouzanfar Sait Mentes Birlik Charles Birungi Gholamreza Roshandel Hailemichael Bizuneh Peter Bjerregaard Justin j Lang Dan j Stein Lilian a Ghandour Tone Bjørge Guilherme Borges Cristina Bosetti Soufiane Boufous Nicola Luigi Bragazzi Hilda l Harb Ali Rostami Hermann Brenner Max Ggriswold Satinath Mukhopadhyay Joseph s Salama Zahid a Butt Sudan Prasad Neupane Sutapa Agrawal Lucero Cahuana-hurtado Bianca Calabria Ismael r Campos-nonato Julio Cesar Campuzano Gregory a Roth Giulia Carreras Saleem m Rana Juan j Carrero Sivadasanpillai Harikrishnan Félix Carvalho Carlos a Castañeda-orjuela Josephine w Ngunjiri Jacqueline Castillo Rivas Sonia Lansky Kalkidan Hassen Abate Ferrán Catalá-lópez Mohammed Mehdi Abrar Rahul Gupta Jung-chen Chang Fiona j Charlson Aparajita Chattopadhyay Pankaj Chaturvedi Rajiv Chowdhury Josep Maria Haro Cuong Tat Nguyen Devasahayam j Christopher Sheng-chia Chung Anders o Larsson Mu'awiyyah Babale Sufiyan Ambuj Roy Liliana g Ciobanu Rafael Moreira Claro Degu Abate Sara Conti Ewerton Cousin Michael h Criqui Berihun Assefa Dachew Long Hoang Nguyen Paul i Dargan Patrick j Sur Hamid Yimam Hassen Nicholas Arian Ahmad Daryani Morsaleh Ganji José Das Neves Kairat Davletov Filipa de Castro Barbora de Courten Solomon m Abay Jan-walter de Neve Bryan l Sykes Trang Huyen Nguyen Louisa Degenhardt Noushin Mohammadifard Gebre Teklemariam Demoz Don c Des Jarlais Nancy Fullman Arman Latifi Subhojit Dey Rupinder Singh Dhaliwal Samath Dhamminda Dharmaratne Rafael Tabarés-seisdedos Meghnath Dhimal David Teye Doku Fares Alahdab Sonali Kochhar Kerrie e Doyle Cristiana Abbafati Manisha Dubey Eleonora Dubljanin Bruce b Duncan Janet l Leasher Takahiro Tabuchi Olatunji o Adetokunboh Hedyeh Ebrahimi Dumessa Edessa Maysaa el Sayed Zaki Mehran Alijanzadeh Dina Nur Anggraini Ningrum Sergei Petrovich Ermakov Holly e Erskine Alireza Esteghamati Mahbobeh Faramarzi Mohammad Tavakkoli Rizwan Suliankatchi Abdulkader Andrea Farioli Paul h Lee Andre Faro Rasmus Havmoeller Yogesh Damodar Sabde Maryam s Farvid Yirga Legesse Nirayo Farshad Farzadfar Valery l Feigin Burcu Kucuk Bicer Simon i Hay Behzad Heibati Andualem Henok Ileana Heredia-pi Norberto Francisco Hernández-llanes James Leigh Basema Saddik Claudiu Herteliu Desalegn ts Tsegaw Hibstu Jean Jacques Noubiap Arash Tehrani-banihashemi Praveen Hoogar Nobuyuki Horita Tara Ballav Adhikari h Dean Hosgood Mostafa Hosseini Mihaela Hostiuc Guoqing hu Saeid Safiri Hsiang Huang Mall Leinsalu Merhawi Gebremedhin Tekle Abdullatif Husseini Cho-il Kim Bulat Idrisov Bogdan Vasile Ileanu Olayinka Stephen Ilesanmi Seyed Sina Naghibi Irvani Jose c Adsuar Sheikh Mohammed Shariful Islam Amirhossein Sahebkar Maria d Jackson Chhabi Lal Ranabhat Mihajlo Jakovljevic Moti Tolera Jalu Janni Leung Richard Ofori-asenso Achala Upendra Jayatilleke Ravi Prakash Jha Jost b Jonas Jacek Jerzy Jozwiak Zubair Kabir Reza Ghadimi Rajendra Kadel Mohsen Afarideh Amaha Kahsay Umesh Kapil Amir Kasaeian Mamata Ghimire Miriam Levi Tesfaye d Dessale Kassa Srinivasa Vittal Katikireddi Norito Kawakami Leopold n Aminde Zikria Saleem Seifu Kebede Adane Teshome Kefale Peter Njenga Keiyoro Andre Pascal Kengne Emilie Elisabet Agardh Yousef Khader Felix Akpojene Ogbo Morteza Abdullatif Khafaie Yichong li Subash Thapa Ibrahim a Khalil Joshua a Salomon md Nuruzzaman Khan Young-ho Khang Muktar Beshir Ahmed Lee-ling Lim Fortune Gbetoho Gankpe Shai Linn Shiwei Liu In-hwan oh Rajeev Gupta Andrea Lobato-cordero Alan d Lopez Carolyn c Gotay Paulo a Lotufo Erlyn Rachelle King Macarayan Isis Eloah Machado Fabiana Madotto Hassan Magdy Abd el Razek Mohammed Akibu Gebremedhin Berhe Gebregergs Nihal Thomas Muhammed Magdy Abd el Razek Olanrewaju Oladimeji Marek Majdan Deena h al Asfoor Reza Majdzadeh Azeem Majeed Reza Malekzadeh Deborah Carvalho Malta Chabila Christopher Mapoma Jose Martinez-raga Roman Topor-madry Pallab k Maulik Mohsen Mazidi Victor Aboyans Andrew t Olagunju Sundeep Santosh Salvi Caitlin Hawley Tomi Akinyemiju Martin Mckee Varshil Mehta Toni Meier Fotis Topouzis Tesfa Mekonen Kidanu Gebremariam Meles Addisu Melese Peter t n Memiah Walter Mendoza Neal d Futran Pedro r Olivares Tsegaye Tewelde Gebrehiwot Desalegn Tadese Mengistu George a Mensah Bach Xuan Tran Nadia Akseer Tuomo j Meretoja Haftay Berhane Mezgebe Tomasz Miazgowski Ted r Miller gk Mini Juan Sanabria Andreea Mirica Bolajoko Olubukunola Olusanya Erkin m Mirrakhimov Christopher e Troeger Johanna m Geleijnse Babak Moazen Khurshid Alam Jacob Olusegun Olusanya Daniel Kim Anu Mary Oommen Eyal Oren Maria Dolores Sanchez-niño Paramjit Singh Gill Heather m Orpana Sargis Aghasi Aghayan Doris d v Ortega-altamirano Justin r Ortiz Erika Ota Mayowa Ojo Owolabi Abayomi Samuel Oyekale Mahesh p a Yun Jin Kim Ammar Albujeer Syed Mohamed Aljunid Adrian Pana David Laith Rawaf Eun-kee Park Ibrahim Abdelmageed Ginawi Charles d h Parry Hadi Parsian Ajay Patle George c Patton Deepak Paudel Max Petzold Gina Agarwal Damian Francesco Santomauro Thomas Clement Truelsen Michael r Phillips Julian David Pillay Kefyalew Addis Alene Maarten j Postma Ababi Zergaw z Giref Farshad Pourmalek Dorairaj Prabhakaran Mostafa Qorbani Amir Radfar Anwar Rafay Mona m Khater Itamar s Santos Ruth w Kimokoti Alireza Rafiei Fakher Rahim Afarin Rahimi-movaghar Mahfuzar Rahman Raghib Ali Philimon n Gona Muhammad Aziz Rahman Rajesh Kumar Rai Nikolaos Tsilimparis Sasa Rajsic Milena m m Santric Milicevic Sree Bhushan Raju Adnan Kisa Usha Ram Abdur Razzaque Sarker Rodrigo Sarmiento-suárez Shafiu Mohammed Nizal Sarrafzadegan Alessandra c Goulart Stefanos Tyrovolas Soewarta Kosen Benn Sartorius Maheswar Satpathy Monika Sawhney Sonia Saxena Ala'a Alkerwi Mete Saylan Michael p Schaub Lorenzo Monasta Maria Inês Schmidt Kingsley Nnanna Ukwaja Ione j c Schneider Ben Schöttker Parvaiz a Koul Felix Greaves Aletta Elisabeth Schutte Falk Schwendicke Sadaf g Sepanlou Masood Ali Shaikh Mehdi Sharif Paula Moraga Walid Ammar Peter Allebeck Jun She Aziz Sheikh Jiabin Shen ai Koyanagi Mekonnen Sisay Shiferaw Giuseppe Grosso Mika Shigematsu Rahman Shiri Kawkab Shishani Vipin Gupta Lidia Morawska Ivy Shiue Sharvari Rahul Shukla Inga Dora Sigfusdottir Nelson Alvis-guzman Diego Augusto Santos Silva Kewal Krishan Natacha Torres da Silva Dayane Gabriele Alves Silveira Yuming Guo Irfan Ullah Dhirendra Narain Sinha Seyyed Meysam Mousavi Freddy Sitas Olalekan a Uthman Pascual r Valdez Salman Rawaf Job f m Van Boven Veena s Kulkarni Kamarul Imran Musa Tommi Juhani Vasankari Narayanaswamy Venketasubramanian Francesco s Violante Sergey Konstantinovitch Vladimirov Vasily Vlassov Stein Emil Vollset Reyna Alma Gutiérrez Robert c Reiner Yaw Ampem Amoako Theo Vos Fasil Wagnew Shiferaw Wagnew Aliya Naheed Pushpendra Kumar Yasir Waheed Yuan-pang Wang Elisabete Weiderpass Fitsum Weldegebreal Kidu Gidey Weldegwergs Sameer Vali Gopalani Andrea Werdecker Ronny Westerman Murthy Gvs Harvey a Whiteford Gurudatta Naik Gianna Gayle Herrera Amul Alessandra Lafranconi Justyna Widecka Tissa Wijeratne Grant m a Wyper Syed Danish Ali Gelin xu Tomohide Yamada Yuichiro Yano Pengpeng ye Ebrahim m Yimer Farid Najafi Pawan Acharya Paul Yip Silvano Gallus Biruck Desalegn Yirsaw Cesar Reis Stephanie r m Zimsen |
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author |
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Eduarda Fernandes Alize j Ferrari Cleusa p Ferri Daniel Obadare Fijabi Zegeye Abebe Irina Filip Jonas David Finger Florian Fischer Abraham d Flaxman Richard Charles Franklin Catalina Liliana Andrei Engida Yisma Naohiro Yonemoto Seok-jun Yoon Marcel Yotebieng Ziyad Al-aly Mustafa z Younis Geevar Zachariah Nima Hafezi-nejad Andre m n Renzaho Adauto Martins Soares Filho Arjun Lakshmana Balaji Zoubida Zaidi Mohammad Zamani Xueying Zhang Sanjay Zodpey Colin Angus Ali h Mokdad Vinay Nangia Mohsen Naghavi Christopher j l Murray Moslem Soofi Mika Kivimäki Emmanuela Gakidou Mustafa Geleto Ansha Ratilal Lalloo Tekleberhan Beyene Hagos Carl Abelardo t Antonio Olatunde Aremu Johan Ärnlöv al Artaman Jobert Richie Nansseu Reed j d Sorensen Krishna k Aryal Karzan Abdulmuhsin Mohammad Reza Assadi Marcel Ausloos Hayley d Tymeson Leticia Avila-burgos Tea Lallukka Euripide f Avokpaho Gessessew Bugssa Hailu Ashish Awasthi Joan b Soriano Henok Tadesse Ayele Mudavath Siva Durga Prasad Nayak Mohammad Sadegh Rezai Rakesh Ayer Tambe b Ayuk Peter s Azzopardi Hamid Badali Alaa Badawi Maciej Banach Hilton Lam Chandrashekhar t Sreeramareddy Vidhya Venkateswaran Suzanne Lyn Barker-collo Randah r Hamadeh Leonardo Roever Chakib Nejjari Lope h Barrero Huda Basaleem Estifanos Baye Shahrzad Bazargan-hejazi Neeraj Bedi Barthelemy Kuate Defo Yannick Béjot Abate Bekele Belachew Faris Hasan Lami Saba Abraham Belay Luca Ronfani Derrick a Bennett Subas Neupane Austin Douglas Tapp Samer Hamidi Isabela m Bensenor Azmeraw t Amare Eduardo Bernabe Robert s Bernstein Addisu Shunu Beyene Tina Beyranvand Soumyadeeep Bhaumik Robin Room Qing Lan Zulfiqar a Bhutta Jagdish Khubchandani Belete Biadgo Nadine Steckling Ali Bijani Nigus Bililign Graeme j Hankey Mohammad h Forouzanfar Sait Mentes Birlik Charles Birungi Gholamreza Roshandel Hailemichael Bizuneh Peter Bjerregaard Justin j Lang Dan j Stein Lilian a Ghandour Tone Bjørge Guilherme Borges Cristina Bosetti Soufiane Boufous Nicola Luigi Bragazzi Hilda l Harb Ali Rostami Hermann Brenner Max Ggriswold Satinath Mukhopadhyay Joseph s Salama Zahid a Butt Sudan Prasad Neupane Sutapa Agrawal Lucero Cahuana-hurtado Bianca Calabria Ismael r Campos-nonato Julio Cesar Campuzano Gregory a Roth Giulia Carreras Saleem m Rana Juan j Carrero Sivadasanpillai Harikrishnan Félix Carvalho Carlos a Castañeda-orjuela Josephine w Ngunjiri Jacqueline Castillo Rivas Sonia Lansky Kalkidan Hassen Abate Ferrán Catalá-lópez Mohammed Mehdi Abrar Rahul Gupta Jung-chen Chang Fiona j Charlson Aparajita Chattopadhyay Pankaj Chaturvedi Rajiv Chowdhury Josep Maria Haro Cuong Tat Nguyen Devasahayam j Christopher Sheng-chia Chung Anders o Larsson Mu'awiyyah Babale Sufiyan Ambuj Roy Liliana g Ciobanu Rafael Moreira Claro Degu Abate Sara Conti Ewerton Cousin Michael h Criqui Berihun Assefa Dachew Long Hoang Nguyen Paul i Dargan Patrick j Sur Hamid Yimam Hassen Nicholas Arian Ahmad Daryani Morsaleh Ganji José Das Neves Kairat Davletov Filipa de Castro Barbora de Courten Solomon m Abay Jan-walter de Neve Bryan l Sykes Trang Huyen Nguyen Louisa Degenhardt Noushin Mohammadifard Gebre Teklemariam Demoz Don c Des Jarlais Nancy Fullman Arman Latifi Subhojit Dey Rupinder Singh Dhaliwal Samath Dhamminda Dharmaratne Rafael Tabarés-seisdedos Meghnath Dhimal David Teye Doku Fares Alahdab Sonali Kochhar Kerrie e Doyle Cristiana Abbafati Manisha Dubey Eleonora Dubljanin Bruce b Duncan Janet l Leasher Takahiro Tabuchi Olatunji o Adetokunboh Hedyeh Ebrahimi Dumessa Edessa Maysaa el Sayed Zaki Mehran Alijanzadeh Dina Nur Anggraini Ningrum Sergei Petrovich Ermakov Holly e Erskine Alireza Esteghamati Mahbobeh Faramarzi Mohammad Tavakkoli Rizwan Suliankatchi Abdulkader Andrea Farioli Paul h Lee Andre Faro Rasmus Havmoeller Yogesh Damodar Sabde Maryam s Farvid Yirga Legesse Nirayo Farshad Farzadfar Valery l Feigin Burcu Kucuk Bicer Simon i Hay Behzad Heibati Andualem Henok Ileana Heredia-pi Norberto Francisco Hernández-llanes James Leigh Basema Saddik Claudiu Herteliu Desalegn ts Tsegaw Hibstu Jean Jacques Noubiap Arash Tehrani-banihashemi Praveen Hoogar Nobuyuki Horita Tara Ballav Adhikari h Dean Hosgood Mostafa Hosseini Mihaela Hostiuc Guoqing hu Saeid Safiri Hsiang Huang Mall Leinsalu Merhawi Gebremedhin Tekle Abdullatif Husseini Cho-il Kim Bulat Idrisov Bogdan Vasile Ileanu Olayinka Stephen Ilesanmi Seyed Sina Naghibi Irvani Jose c Adsuar Sheikh Mohammed Shariful Islam Amirhossein Sahebkar Maria d Jackson Chhabi Lal Ranabhat Mihajlo Jakovljevic Moti Tolera Jalu Janni Leung Richard Ofori-asenso Achala Upendra Jayatilleke Ravi Prakash Jha Jost b Jonas Jacek Jerzy Jozwiak Zubair Kabir Reza Ghadimi Rajendra Kadel Mohsen Afarideh Amaha Kahsay Umesh Kapil Amir Kasaeian Mamata Ghimire Miriam Levi Tesfaye d Dessale Kassa Srinivasa Vittal Katikireddi Norito Kawakami Leopold n Aminde Zikria Saleem Seifu Kebede Adane Teshome Kefale Peter Njenga Keiyoro Andre Pascal Kengne Emilie Elisabet Agardh Yousef Khader Felix Akpojene Ogbo Morteza Abdullatif Khafaie Yichong li Subash Thapa Ibrahim a Khalil Joshua a Salomon md Nuruzzaman Khan Young-ho Khang Muktar Beshir Ahmed Lee-ling Lim Fortune Gbetoho Gankpe Shai Linn Shiwei Liu In-hwan oh Rajeev Gupta Andrea Lobato-cordero Alan d Lopez Carolyn c Gotay Paulo a Lotufo Erlyn Rachelle King Macarayan Isis Eloah Machado Fabiana Madotto Hassan Magdy Abd el Razek Mohammed Akibu Gebremedhin Berhe Gebregergs Nihal Thomas Muhammed Magdy Abd el Razek Olanrewaju Oladimeji Marek Majdan Deena h al Asfoor Reza Majdzadeh Azeem Majeed Reza Malekzadeh Deborah Carvalho Malta Chabila Christopher Mapoma Jose Martinez-raga Roman Topor-madry Pallab k Maulik Mohsen Mazidi Victor Aboyans Andrew t Olagunju Sundeep Santosh Salvi Caitlin Hawley Tomi Akinyemiju Martin Mckee Varshil Mehta Toni Meier Fotis Topouzis Tesfa Mekonen Kidanu Gebremariam Meles Addisu Melese Peter t n Memiah Walter Mendoza Neal d Futran Pedro r Olivares Tsegaye Tewelde Gebrehiwot Desalegn Tadese Mengistu George a Mensah Bach Xuan Tran Nadia Akseer Tuomo j Meretoja Haftay Berhane Mezgebe Tomasz Miazgowski Ted r Miller gk Mini Juan Sanabria Andreea Mirica Bolajoko Olubukunola Olusanya Erkin m Mirrakhimov Christopher e Troeger Johanna m Geleijnse Babak Moazen Khurshid Alam Jacob Olusegun Olusanya Daniel Kim Anu Mary Oommen Eyal Oren Maria Dolores Sanchez-niño Paramjit Singh Gill Heather m Orpana Sargis Aghasi Aghayan Doris d v Ortega-altamirano Justin r Ortiz Erika Ota Mayowa Ojo Owolabi Abayomi Samuel Oyekale Mahesh p a Yun Jin Kim Ammar Albujeer Syed Mohamed Aljunid Adrian Pana David Laith Rawaf Eun-kee Park Ibrahim Abdelmageed Ginawi Charles d h Parry Hadi Parsian Ajay Patle George c Patton Deepak Paudel Max Petzold Gina Agarwal Damian Francesco Santomauro Thomas Clement Truelsen Michael r Phillips Julian David Pillay Kefyalew Addis Alene Maarten j Postma Ababi Zergaw z Giref Farshad Pourmalek Dorairaj Prabhakaran Mostafa Qorbani Amir Radfar Anwar Rafay Mona m Khater Itamar s Santos Ruth w Kimokoti Alireza Rafiei Fakher Rahim Afarin Rahimi-movaghar Mahfuzar Rahman Raghib Ali Philimon n Gona Muhammad Aziz Rahman Rajesh Kumar Rai Nikolaos Tsilimparis Sasa Rajsic Milena m m Santric Milicevic Sree Bhushan Raju Adnan Kisa Usha Ram Abdur Razzaque Sarker Rodrigo Sarmiento-suárez Shafiu Mohammed Nizal Sarrafzadegan Alessandra c Goulart Stefanos Tyrovolas Soewarta Kosen Benn Sartorius Maheswar Satpathy Monika Sawhney Sonia Saxena Ala'a Alkerwi Mete Saylan Michael p Schaub Lorenzo Monasta Maria Inês Schmidt Kingsley Nnanna Ukwaja Ione j c Schneider Ben Schöttker Parvaiz a Koul Felix Greaves Aletta Elisabeth Schutte Falk Schwendicke Sadaf g Sepanlou Masood Ali Shaikh Mehdi Sharif Paula Moraga Walid Ammar Peter Allebeck Jun She Aziz Sheikh Jiabin Shen ai Koyanagi Mekonnen Sisay Shiferaw Giuseppe Grosso Mika Shigematsu Rahman Shiri Kawkab Shishani Vipin Gupta Lidia Morawska Ivy Shiue Sharvari Rahul Shukla Inga Dora Sigfusdottir Nelson Alvis-guzman Diego Augusto Santos Silva Kewal Krishan Natacha Torres da Silva Dayane Gabriele Alves Silveira Yuming Guo Irfan Ullah Dhirendra Narain Sinha Seyyed Meysam Mousavi Freddy Sitas Olalekan a Uthman Pascual r Valdez Salman Rawaf Job f m Van Boven Veena s Kulkarni Kamarul Imran Musa Tommi Juhani Vasankari Narayanaswamy Venketasubramanian Francesco s Violante Sergey Konstantinovitch Vladimirov Vasily Vlassov Stein Emil Vollset Reyna Alma Gutiérrez Robert c Reiner Yaw Ampem Amoako Theo Vos Fasil Wagnew Shiferaw Wagnew Aliya Naheed Pushpendra Kumar Yasir Waheed Yuan-pang Wang Elisabete Weiderpass Fitsum Weldegebreal Kidu Gidey Weldegwergs Sameer Vali Gopalani Andrea Werdecker Ronny Westerman Murthy Gvs Harvey a Whiteford Gurudatta Naik Gianna Gayle Herrera Amul Alessandra Lafranconi Justyna Widecka Tissa Wijeratne Grant m a Wyper Syed Danish Ali Gelin xu Tomohide Yamada Yuichiro Yano Pengpeng ye Ebrahim m Yimer Farid Najafi Pawan Acharya Paul Yip Silvano Gallus Biruck Desalegn Yirsaw Cesar Reis Stephanie r m Zimsen |
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Mariana Santos Felisbino-mendes Eduarda Fernandes Alize j Ferrari Cleusa p Ferri Daniel Obadare Fijabi Zegeye Abebe Irina Filip Jonas David Finger Florian Fischer Abraham d Flaxman Richard Charles Franklin Catalina Liliana Andrei Engida Yisma Naohiro Yonemoto Seok-jun Yoon Marcel Yotebieng Ziyad Al-aly Mustafa z Younis Geevar Zachariah Nima Hafezi-nejad Andre m n Renzaho Adauto Martins Soares Filho Arjun Lakshmana Balaji Zoubida Zaidi Mohammad Zamani Xueying Zhang Sanjay Zodpey Colin Angus Ali h Mokdad Vinay Nangia Mohsen Naghavi Christopher j l Murray Moslem Soofi Mika Kivimäki Emmanuela Gakidou Mustafa Geleto Ansha Ratilal Lalloo Tekleberhan Beyene Hagos Carl Abelardo t Antonio Olatunde Aremu Johan Ärnlöv al Artaman Jobert Richie Nansseu Reed j d Sorensen Krishna k Aryal Karzan Abdulmuhsin Mohammad Reza Assadi Marcel Ausloos Hayley d Tymeson Leticia Avila-burgos Tea Lallukka Euripide f Avokpaho Gessessew Bugssa Hailu Ashish Awasthi Joan b Soriano Henok Tadesse Ayele Mudavath Siva Durga Prasad Nayak Mohammad Sadegh Rezai Rakesh Ayer Tambe b Ayuk Peter s Azzopardi Hamid Badali Alaa Badawi Maciej Banach Hilton Lam Chandrashekhar t Sreeramareddy Vidhya Venkateswaran Suzanne Lyn Barker-collo Randah r Hamadeh Leonardo Roever Chakib Nejjari Lope h Barrero Huda Basaleem Estifanos Baye Shahrzad Bazargan-hejazi Neeraj Bedi Barthelemy Kuate Defo Yannick Béjot Abate Bekele Belachew Faris Hasan Lami Saba Abraham Belay Luca Ronfani Derrick a Bennett Subas Neupane Austin Douglas Tapp Samer Hamidi Isabela m Bensenor Azmeraw t Amare Eduardo Bernabe Robert s Bernstein Addisu Shunu Beyene Tina Beyranvand Soumyadeeep Bhaumik Robin Room Qing Lan Zulfiqar a Bhutta Jagdish Khubchandani Belete Biadgo Nadine Steckling Ali Bijani Nigus Bililign Graeme j Hankey Mohammad h Forouzanfar Sait Mentes Birlik Charles Birungi Gholamreza Roshandel Hailemichael Bizuneh Peter Bjerregaard Justin j Lang Dan j Stein Lilian a Ghandour Tone Bjørge Guilherme Borges Cristina Bosetti Soufiane Boufous Nicola Luigi Bragazzi Hilda l Harb Ali Rostami Hermann Brenner Max Ggriswold Satinath Mukhopadhyay Joseph s Salama Zahid a Butt Sudan Prasad Neupane Sutapa Agrawal Lucero Cahuana-hurtado Bianca Calabria Ismael r Campos-nonato Julio Cesar Campuzano Gregory a Roth Giulia Carreras Saleem m Rana Juan j Carrero Sivadasanpillai Harikrishnan Félix Carvalho Carlos a Castañeda-orjuela Josephine w Ngunjiri Jacqueline Castillo Rivas Sonia Lansky Kalkidan Hassen Abate Ferrán Catalá-lópez Mohammed Mehdi Abrar Rahul Gupta Jung-chen Chang Fiona j Charlson Aparajita Chattopadhyay Pankaj Chaturvedi Rajiv Chowdhury Josep Maria Haro Cuong Tat Nguyen Devasahayam j Christopher Sheng-chia Chung Anders o Larsson Mu'awiyyah Babale Sufiyan Ambuj Roy Liliana g Ciobanu Rafael Moreira Claro Degu Abate Sara Conti Ewerton Cousin Michael h Criqui Berihun Assefa Dachew Long Hoang Nguyen Paul i Dargan Patrick j Sur Hamid Yimam Hassen Nicholas Arian Ahmad Daryani Morsaleh Ganji José Das Neves Kairat Davletov Filipa de Castro Barbora de Courten Solomon m Abay Jan-walter de Neve Bryan l Sykes Trang Huyen Nguyen Louisa Degenhardt Noushin Mohammadifard Gebre Teklemariam Demoz Don c Des Jarlais Nancy Fullman Arman Latifi Subhojit Dey Rupinder Singh Dhaliwal Samath Dhamminda Dharmaratne Rafael Tabarés-seisdedos Meghnath Dhimal David Teye Doku Fares Alahdab Sonali Kochhar Kerrie e Doyle Cristiana Abbafati Manisha Dubey Eleonora Dubljanin Bruce b Duncan Janet l Leasher Takahiro Tabuchi Olatunji o Adetokunboh Hedyeh Ebrahimi Dumessa Edessa Maysaa el Sayed Zaki Mehran Alijanzadeh Dina Nur Anggraini Ningrum Sergei Petrovich Ermakov Holly e Erskine Alireza Esteghamati Mahbobeh Faramarzi Mohammad Tavakkoli Rizwan Suliankatchi Abdulkader Andrea Farioli Paul h Lee Andre Faro Rasmus Havmoeller Yogesh Damodar Sabde Maryam s Farvid Yirga Legesse Nirayo Farshad Farzadfar Valery l Feigin Burcu Kucuk Bicer Simon i Hay Behzad Heibati Andualem Henok Ileana Heredia-pi Norberto Francisco Hernández-llanes James Leigh Basema Saddik Claudiu Herteliu Desalegn ts Tsegaw Hibstu Jean Jacques Noubiap Arash Tehrani-banihashemi Praveen Hoogar Nobuyuki Horita Tara Ballav Adhikari h Dean Hosgood Mostafa Hosseini Mihaela Hostiuc Guoqing hu Saeid Safiri Hsiang Huang Mall Leinsalu Merhawi Gebremedhin Tekle Abdullatif Husseini Cho-il Kim Bulat Idrisov Bogdan Vasile Ileanu Olayinka Stephen Ilesanmi Seyed Sina Naghibi Irvani Jose c Adsuar Sheikh Mohammed Shariful Islam Amirhossein Sahebkar Maria d Jackson Chhabi Lal Ranabhat Mihajlo Jakovljevic Moti Tolera Jalu Janni Leung Richard Ofori-asenso Achala Upendra Jayatilleke Ravi Prakash Jha Jost b Jonas Jacek Jerzy Jozwiak Zubair Kabir Joseph s Salama Reza Ghadimi Rajendra Kadel Mohsen Afarideh Amaha Kahsay Umesh Kapil Amir Kasaeian Mamata Ghimire Miriam Levi Tesfaye d Dessale Kassa Srinivasa Vittal Katikireddi Norito Kawakami Leopold n Aminde Zikria Saleem Seifu Kebede Adane Teshome Kefale Peter Njenga Keiyoro Andre Pascal Kengne Emilie Elisabet Agardh Yousef Khader Felix Akpojene Ogbo Morteza Abdullatif Khafaie Yichong li Subash Thapa Ibrahim a Khalil Joshua a Salomon md Nuruzzaman Khan Young-ho Khang Muktar Beshir Ahmed Lee-ling Lim Fortune Gbetoho Gankpe Shai Linn Shiwei Liu In-hwan oh Rajeev Gupta Andrea Lobato-cordero Alan d Lopez Carolyn c Gotay Paulo a Lotufo Erlyn Rachelle King Macarayan Isis Eloah Machado Fabiana Madotto Hassan Magdy Abd el Razek Mohammed Akibu Gebremedhin Berhe Gebregergs Nihal Thomas Muhammed Magdy Abd el Razek Olanrewaju Oladimeji Marek Majdan Deena h al Asfoor Reza Majdzadeh Azeem Majeed Reza Malekzadeh Deborah Carvalho Malta Chabila Christopher Mapoma Jose Martinez-raga Roman Topor-madry Pallab k Maulik Mohsen Mazidi Victor Aboyans Andrew t Olagunju Sundeep Santosh Salvi Caitlin Hawley Tomi Akinyemiju Martin Mckee Varshil Mehta Toni Meier Fotis Topouzis Tesfa Mekonen Kidanu Gebremariam Meles Addisu Melese Peter t n Memiah Walter Mendoza Neal d Futran Pedro r Olivares Tsegaye Tewelde Gebrehiwot Desalegn Tadese Mengistu George a Mensah Bach Xuan Tran Nadia Akseer Tuomo j Meretoja Haftay Berhane Mezgebe Tomasz Miazgowski Ted r Miller gk Mini Juan Sanabria Andreea Mirica Bolajoko Olubukunola Olusanya Erkin m Mirrakhimov Christopher e Troeger Johanna m Geleijnse Babak Moazen Khurshid Alam Jacob Olusegun Olusanya Daniel Kim Anu Mary Oommen Eyal Oren Maria Dolores Sanchez-niño Paramjit Singh Gill Heather m Orpana Sargis Aghasi Aghayan Doris d v Ortega-altamirano Justin r Ortiz Erika Ota Mayowa Ojo Owolabi Abayomi Samuel Oyekale Mahesh p a Yun Jin Kim Ammar Albujeer Syed Mohamed Aljunid Adrian Pana David Laith Rawaf Eun-kee Park Ibrahim Abdelmageed Ginawi Charles d h Parry Hadi Parsian Ajay Patle George c Patton Deepak Paudel Max Petzold Gina Agarwal Damian Francesco Santomauro Thomas Clement Truelsen Michael r Phillips Julian David Pillay Kefyalew Addis Alene Maarten j Postma Ababi Zergaw z Giref Farshad Pourmalek Dorairaj Prabhakaran Mostafa Qorbani Amir Radfar Anwar Rafay Mona m Khater Itamar s Santos Ruth w Kimokoti Alireza Rafiei Fakher Rahim Afarin Rahimi-movaghar Mahfuzar Rahman Raghib Ali Philimon n Gona Muhammad Aziz Rahman Rajesh Kumar Rai Nikolaos Tsilimparis Sasa Rajsic Milena m m Santric Milicevic Sree Bhushan Raju Adnan Kisa Usha Ram Abdur Razzaque Sarker Rodrigo Sarmiento-suárez Shafiu Mohammed Nizal Sarrafzadegan Alessandra c Goulart Stefanos Tyrovolas Soewarta Kosen Benn Sartorius Maheswar Satpathy Monika Sawhney Sonia Saxena Ala'a Alkerwi Mete Saylan Michael p Schaub Lorenzo Monasta Maria Inês Schmidt Kingsley Nnanna Ukwaja Ione j c Schneider Ben Schöttker Parvaiz a Koul Felix Greaves Aletta Elisabeth Schutte Falk Schwendicke Sadaf g Sepanlou Masood Ali Shaikh Mehdi Sharif Paula Moraga Walid Ammar Peter Allebeck Jun She Aziz Sheikh Jiabin Shen ai Koyanagi Mekonnen Sisay Shiferaw Giuseppe Grosso Mika Shigematsu Rahman Shiri Kawkab Shishani Vipin Gupta Lidia Morawska Ivy Shiue Sharvari Rahul Shukla Inga Dora Sigfusdottir Nelson Alvis-guzman Diego Augusto Santos Silva Kewal Krishan Natacha Torres da Silva Dayane Gabriele Alves Silveira Yuming Guo Irfan Ullah Dhirendra Narain Sinha Seyyed Meysam Mousavi Freddy Sitas Olalekan a Uthman Pascual r Valdez Salman Rawaf Job f m Van Boven Veena s Kulkarni Kamarul Imran Musa Tommi Juhani Vasankari Narayanaswamy Venketasubramanian Francesco s Violante Sergey Konstantinovitch Vladimirov Vasily Vlassov Stein Emil Vollset Reyna Alma Gutiérrez Robert c Reiner Yaw Ampem Amoako Theo Vos Fasil Wagnew Shiferaw Wagnew Aliya Naheed Pushpendra Kumar Yasir Waheed Yuan-pang Wang Elisabete Weiderpass Fitsum Weldegebreal Kidu Gidey Weldegwergs Sameer Vali Gopalani Andrea Werdecker Ronny Westerman Murthy Gvs Harvey a Whiteford Gurudatta Naik Gianna Gayle Herrera Amul Alessandra Lafranconi Justyna Widecka Tissa Wijeratne Grant m a Wyper Syed Danish Ali Gelin xu Tomohide Yamada Yuichiro Yano Pengpeng ye Ebrahim m Yimer Farid Najafi Pawan Acharya Paul Yip Silvano Gallus Biruck Desalegn Yirsaw Cesar Reis Stephanie r m Zimsen |
dc.subject.por.fl_str_mv |
Alcohol Abuse Global Burden of Disease Alcoolismo Carga Global da Doença |
topic |
Alcohol Abuse Global Burden of Disease Alcoolismo Carga Global da Doença |
description |
Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks perweek.Interpretation. Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that therisk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018 2023-04-17T21:04:15Z 2023-04-17T21:04:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.1016/S0140-6736(18)31310-2 01406736 http://hdl.handle.net/1843/52085 https://orcid.org/0000-0002-8214-5734 |
url |
https://doi.org/10.1016/S0140-6736(18)31310-2 http://hdl.handle.net/1843/52085 https://orcid.org/0000-0002-8214-5734 |
identifier_str_mv |
01406736 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
The Lancet |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais Brasil ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA ENF - DEPARTAMENTO DE NUTRIÇÃO UFMG |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais Brasil ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA ENF - DEPARTAMENTO DE NUTRIÇÃO UFMG |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Repositório Institucional da UFMG |
collection |
Repositório Institucional da UFMG |
repository.name.fl_str_mv |
Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
repositorio@ufmg.br |
_version_ |
1823247942763413504 |