Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016

Detalhes bibliográficos
Autor(a) principal: Mariana Santos Felisbino-mendes
Data de Publicação: 2018
Outros Autores: Eduarda Fernandes, Alize j Ferrari, Cleusa p Ferri, Daniel Obadare Fijabi, Zegeye Abebe, Irina Filip, Jonas David Finger, Florian Fischer, Abraham d Flaxman, Richard Charles Franklin, Catalina Liliana Andrei, Engida Yisma, Naohiro Yonemoto, Seok-jun Yoon, Marcel Yotebieng, Ziyad Al-aly, Mustafa z Younis, Geevar Zachariah, Nima Hafezi-nejad, Andre m n Renzaho, Adauto Martins Soares Filho, Arjun Lakshmana Balaji, Zoubida Zaidi, Mohammad Zamani, Xueying Zhang, Sanjay Zodpey, Colin Angus, Ali h Mokdad, Vinay Nangia, Mohsen Naghavi, Christopher j l Murray, Moslem Soofi, Mika Kivimäki, Emmanuela Gakidou, Mustafa Geleto Ansha, Ratilal Lalloo, Tekleberhan Beyene Hagos, Carl Abelardo t Antonio, Olatunde Aremu, Johan Ärnlöv, al Artaman, Jobert Richie Nansseu, Reed j d Sorensen, Krishna k Aryal, Karzan Abdulmuhsin Mohammad, Reza Assadi, Marcel Ausloos, Hayley d Tymeson, Leticia Avila-burgos, Tea Lallukka, Euripide f Avokpaho, Gessessew Bugssa Hailu, Ashish Awasthi, Joan b Soriano, Henok Tadesse Ayele, Mudavath Siva Durga Prasad Nayak, Mohammad Sadegh Rezai, Rakesh Ayer, Tambe b Ayuk, Peter s Azzopardi, Hamid Badali, Alaa Badawi, Maciej Banach, Hilton Lam, Chandrashekhar t Sreeramareddy, Vidhya Venkateswaran, Suzanne Lyn Barker-collo, Randah r Hamadeh, Leonardo Roever, Chakib Nejjari, Lope h Barrero, Huda Basaleem, Estifanos Baye, Shahrzad Bazargan-hejazi, Neeraj Bedi, Barthelemy Kuate Defo, Yannick Béjot, Abate Bekele Belachew, Faris Hasan Lami, Saba Abraham Belay, Luca Ronfani, Derrick a Bennett, Subas Neupane, Austin Douglas Tapp, Samer Hamidi, Isabela m Bensenor, Azmeraw t Amare, Eduardo Bernabe, Robert s Bernstein, Addisu Shunu Beyene, Tina Beyranvand, Soumyadeeep Bhaumik, Robin Room, Qing Lan, Zulfiqar a Bhutta, Jagdish Khubchandani, Belete Biadgo, Nadine Steckling, Ali Bijani, Nigus Bililign, Graeme j Hankey, Mohammad h Forouzanfar, Sait Mentes Birlik, Charles Birungi, Gholamreza Roshandel, Hailemichael Bizuneh, Peter Bjerregaard, Justin j Lang, Dan j Stein, Lilian a Ghandour, Tone Bjørge, Guilherme Borges, Cristina Bosetti, Soufiane Boufous, Nicola Luigi Bragazzi, Hilda l Harb, Ali Rostami, Hermann Brenner, Max Ggriswold, Satinath Mukhopadhyay, Joseph s Salama, Zahid a Butt, Sudan Prasad Neupane, Sutapa Agrawal, Lucero Cahuana-hurtado, Bianca Calabria, Ismael r Campos-nonato, Julio Cesar Campuzano, Gregory a Roth, Giulia Carreras, Saleem m Rana, Juan j Carrero, Sivadasanpillai Harikrishnan, Félix Carvalho, Carlos a Castañeda-orjuela, Josephine w Ngunjiri, Jacqueline Castillo Rivas, Sonia Lansky, Kalkidan Hassen Abate, Ferrán Catalá-lópez, Mohammed Mehdi Abrar, Rahul Gupta, Jung-chen Chang, Fiona j Charlson, Aparajita Chattopadhyay, Pankaj Chaturvedi, Rajiv Chowdhury, Josep Maria Haro, Cuong Tat Nguyen, Devasahayam j Christopher, Sheng-chia Chung, Anders o Larsson, Mu'awiyyah Babale Sufiyan, Ambuj Roy, Liliana g Ciobanu, Rafael Moreira Claro, Degu Abate, Sara Conti, Ewerton Cousin, Michael h Criqui, Berihun Assefa Dachew, Long Hoang Nguyen, Paul i Dargan, Patrick j Sur, Hamid Yimam Hassen, Nicholas Arian, Ahmad Daryani, Morsaleh Ganji, José Das Neves, Kairat Davletov, Filipa de Castro, Barbora de Courten, Solomon m Abay, Jan-walter de Neve, Bryan l Sykes, Trang Huyen Nguyen, Louisa Degenhardt, Noushin Mohammadifard, Gebre Teklemariam Demoz, Don c Des Jarlais, Nancy Fullman, Arman Latifi, Subhojit Dey, Rupinder Singh Dhaliwal, Samath Dhamminda Dharmaratne, Rafael Tabarés-seisdedos, Meghnath Dhimal, David Teye Doku, Fares Alahdab, Sonali Kochhar, Kerrie e Doyle, Cristiana Abbafati, Manisha Dubey, Eleonora Dubljanin, Bruce b Duncan, Janet l Leasher, Takahiro Tabuchi, Olatunji o Adetokunboh, Hedyeh Ebrahimi, Dumessa Edessa, Maysaa el Sayed Zaki, Mehran Alijanzadeh, Dina Nur Anggraini Ningrum, Sergei Petrovich Ermakov, Holly e Erskine, Alireza Esteghamati, Mahbobeh Faramarzi, Mohammad Tavakkoli, Rizwan Suliankatchi Abdulkader, Andrea Farioli, Paul h Lee, Andre Faro, Rasmus Havmoeller, Yogesh Damodar Sabde, Maryam s Farvid, Yirga Legesse Nirayo, Farshad Farzadfar, Valery l Feigin, Burcu Kucuk Bicer, Simon i Hay, Behzad Heibati, Andualem Henok, Ileana Heredia-pi, Norberto Francisco Hernández-llanes, James Leigh, Basema Saddik, Claudiu Herteliu, Desalegn ts Tsegaw Hibstu, Jean Jacques Noubiap, Arash Tehrani-banihashemi, Praveen Hoogar, Nobuyuki Horita, Tara Ballav Adhikari, h Dean Hosgood, Mostafa Hosseini, Mihaela Hostiuc, Guoqing hu, Saeid Safiri, Hsiang Huang, Mall Leinsalu, Merhawi Gebremedhin Tekle, Abdullatif Husseini, Cho-il Kim, Bulat Idrisov, Bogdan Vasile Ileanu, Olayinka Stephen Ilesanmi, Seyed Sina Naghibi Irvani, Jose c Adsuar, Sheikh Mohammed Shariful Islam, Amirhossein Sahebkar, Maria d Jackson, Chhabi Lal Ranabhat, Mihajlo Jakovljevic, Moti Tolera Jalu, Janni Leung, Richard Ofori-asenso, Achala Upendra Jayatilleke, Ravi Prakash Jha, Jost b Jonas, Jacek Jerzy Jozwiak, Zubair Kabir, Reza Ghadimi, Rajendra Kadel, Mohsen Afarideh, Amaha Kahsay, Umesh Kapil, Amir Kasaeian, Mamata Ghimire, Miriam Levi, Tesfaye d Dessale Kassa, Srinivasa Vittal Katikireddi, Norito Kawakami, Leopold n Aminde, Zikria Saleem, Seifu Kebede, Adane Teshome Kefale, Peter Njenga Keiyoro, Andre Pascal Kengne, Emilie Elisabet Agardh, Yousef Khader, Felix Akpojene Ogbo, Morteza Abdullatif Khafaie, Yichong li, Subash Thapa, Ibrahim a Khalil, Joshua a Salomon, md Nuruzzaman Khan, Young-ho Khang, Muktar Beshir Ahmed, Lee-ling Lim, Fortune Gbetoho Gankpe, Shai Linn, Shiwei Liu, In-hwan oh, Rajeev Gupta, Andrea Lobato-cordero, Alan d Lopez, Carolyn c Gotay, Paulo a Lotufo, Erlyn Rachelle King Macarayan, Isis Eloah Machado, Fabiana Madotto, Hassan Magdy Abd el Razek, Mohammed Akibu, Gebremedhin Berhe Gebregergs, Nihal Thomas, Muhammed Magdy Abd el Razek, Olanrewaju Oladimeji, Marek Majdan, Deena h al Asfoor, Reza Majdzadeh, Azeem Majeed, Reza Malekzadeh, Deborah Carvalho Malta, Chabila Christopher Mapoma, Jose Martinez-raga, Roman Topor-madry, Pallab k Maulik, Mohsen Mazidi, Victor Aboyans, Andrew t Olagunju, Sundeep Santosh Salvi, Caitlin Hawley, Tomi Akinyemiju, Martin Mckee, Varshil Mehta, Toni Meier, Fotis Topouzis, Tesfa Mekonen, Kidanu Gebremariam Meles, Addisu Melese, Peter t n Memiah, Walter Mendoza, Neal d Futran, Pedro r Olivares, Tsegaye Tewelde Gebrehiwot, Desalegn Tadese Mengistu, George a Mensah, Bach Xuan Tran, Nadia Akseer, Tuomo j Meretoja, Haftay Berhane Mezgebe, Tomasz Miazgowski, Ted r Miller, gk Mini, Juan Sanabria, Andreea Mirica, Bolajoko Olubukunola Olusanya, Erkin m Mirrakhimov, Christopher e Troeger, Johanna m Geleijnse, Babak Moazen, Khurshid Alam, Jacob Olusegun Olusanya, Daniel Kim, Anu Mary Oommen, Eyal Oren, Maria Dolores Sanchez-niño, Paramjit Singh Gill, Heather m Orpana, Sargis Aghasi Aghayan, Doris d v Ortega-altamirano, Justin r Ortiz, Erika Ota, Mayowa Ojo Owolabi, Abayomi Samuel Oyekale, Mahesh p a, Yun Jin Kim, Ammar Albujeer, Syed Mohamed Aljunid, Adrian Pana, David Laith Rawaf, Eun-kee Park, Ibrahim Abdelmageed Ginawi, Charles d h Parry, Hadi Parsian, Ajay Patle, George c Patton, Deepak Paudel, Max Petzold, Gina Agarwal, Damian Francesco Santomauro, Thomas Clement Truelsen, Michael r Phillips, Julian David Pillay, Kefyalew Addis Alene, Maarten j Postma, Ababi Zergaw z Giref, Farshad Pourmalek, Dorairaj Prabhakaran, Mostafa Qorbani, Amir Radfar, Anwar Rafay, Mona m Khater, Itamar s Santos, Ruth w Kimokoti, Alireza Rafiei, Fakher Rahim, Afarin Rahimi-movaghar, Mahfuzar Rahman, Raghib Ali, Philimon n Gona, Muhammad Aziz Rahman, Rajesh Kumar Rai, Nikolaos Tsilimparis, Sasa Rajsic, Milena m m Santric Milicevic, Sree Bhushan Raju, Adnan Kisa, Usha Ram, Abdur Razzaque Sarker, Rodrigo Sarmiento-suárez, Shafiu Mohammed, Nizal Sarrafzadegan, Alessandra c Goulart, Stefanos Tyrovolas, Soewarta Kosen, Benn Sartorius, Maheswar Satpathy, Monika Sawhney, Sonia Saxena, Ala'a Alkerwi, Mete Saylan, Michael p Schaub, Lorenzo Monasta, Maria Inês Schmidt, Kingsley Nnanna Ukwaja, Ione j c Schneider, Ben Schöttker, Parvaiz a Koul, Felix Greaves, Aletta Elisabeth Schutte, Falk Schwendicke, Sadaf g Sepanlou, Masood Ali Shaikh, Mehdi Sharif, Paula Moraga, Walid Ammar, Peter Allebeck, Jun She, Aziz Sheikh, Jiabin Shen, ai Koyanagi, Mekonnen Sisay Shiferaw, Giuseppe Grosso, Mika Shigematsu, Rahman Shiri, Kawkab Shishani, Vipin Gupta, Lidia Morawska, Ivy Shiue, Sharvari Rahul Shukla, Inga Dora Sigfusdottir, Nelson Alvis-guzman, Diego Augusto Santos Silva, Kewal Krishan, Natacha Torres da Silva, Dayane Gabriele Alves Silveira, Yuming Guo, Irfan Ullah, Dhirendra Narain Sinha, Seyyed Meysam Mousavi, Freddy Sitas, Olalekan a Uthman, Pascual r Valdez, Salman Rawaf, Job f m Van Boven, Veena s Kulkarni, Kamarul Imran Musa, Tommi Juhani Vasankari, Narayanaswamy Venketasubramanian, Francesco s Violante, Sergey Konstantinovitch Vladimirov, Vasily Vlassov, Stein Emil Vollset, Reyna Alma Gutiérrez, Robert c Reiner, Yaw Ampem Amoako, Theo Vos, Fasil Wagnew Shiferaw Wagnew, Aliya Naheed, Pushpendra Kumar, Yasir Waheed, Yuan-pang Wang, Elisabete Weiderpass, Fitsum Weldegebreal, Kidu Gidey Weldegwergs, Sameer Vali Gopalani, Andrea Werdecker, Ronny Westerman, Murthy Gvs, Harvey a Whiteford, Gurudatta Naik, Gianna Gayle Herrera Amul, Alessandra Lafranconi, Justyna Widecka, Tissa Wijeratne, Grant m a Wyper, Syed Danish Ali, Gelin xu, Tomohide Yamada, Yuichiro Yano, Pengpeng ye, Ebrahim m Yimer, Farid Najafi, Pawan Acharya, Paul Yip, Silvano Gallus, Biruck Desalegn Yirsaw, Cesar Reis, Stephanie r m Zimsen
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1016/S0140-6736(18)31310-2
http://hdl.handle.net/1843/52085
https://orcid.org/0000-0002-8214-5734
Resumo: Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks perweek.Interpretation. Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that therisk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption.
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spelling Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016Alcohol AbuseGlobal Burden of DiseaseAlcoolismoCarga Global da DoençaBackground Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks perweek.Interpretation. Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that therisk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption.Universidade Federal de Minas GeraisBrasilENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICAENF - DEPARTAMENTO DE NUTRIÇÃOUFMG2023-04-17T21:04:15Z2023-04-17T21:04:15Z2018info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlepdfapplication/pdfhttps://doi.org/10.1016/S0140-6736(18)31310-201406736http://hdl.handle.net/1843/52085https://orcid.org/0000-0002-8214-5734engThe LancetMariana Santos Felisbino-mendesEduarda FernandesAlize j FerrariCleusa p FerriDaniel Obadare FijabiZegeye AbebeIrina FilipJonas David FingerFlorian FischerAbraham d FlaxmanRichard Charles FranklinCatalina Liliana AndreiEngida YismaNaohiro YonemotoSeok-jun YoonMarcel YotebiengZiyad Al-alyMustafa z YounisGeevar ZachariahNima Hafezi-nejadAndre m n RenzahoAdauto Martins Soares FilhoArjun Lakshmana BalajiZoubida ZaidiMohammad ZamaniXueying 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dc.title.none.fl_str_mv Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
title Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
spellingShingle Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
Mariana Santos Felisbino-mendes
Alcohol Abuse
Global Burden of Disease
Alcoolismo
Carga Global da Doença
title_short Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
title_full Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
title_fullStr Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
title_full_unstemmed Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
title_sort Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016
author Mariana Santos Felisbino-mendes
author_facet Mariana Santos Felisbino-mendes
Eduarda Fernandes
Alize j Ferrari
Cleusa p Ferri
Daniel Obadare Fijabi
Zegeye Abebe
Irina Filip
Jonas David Finger
Florian Fischer
Abraham d Flaxman
Richard Charles Franklin
Catalina Liliana Andrei
Engida Yisma
Naohiro Yonemoto
Seok-jun Yoon
Marcel Yotebieng
Ziyad Al-aly
Mustafa z Younis
Geevar Zachariah
Nima Hafezi-nejad
Andre m n Renzaho
Adauto Martins Soares Filho
Arjun Lakshmana Balaji
Zoubida Zaidi
Mohammad Zamani
Xueying Zhang
Sanjay Zodpey
Colin Angus
Ali h Mokdad
Vinay Nangia
Mohsen Naghavi
Christopher j l Murray
Moslem Soofi
Mika Kivimäki
Emmanuela Gakidou
Mustafa Geleto Ansha
Ratilal Lalloo
Tekleberhan Beyene Hagos
Carl Abelardo t Antonio
Olatunde Aremu
Johan Ärnlöv
al Artaman
Jobert Richie Nansseu
Reed j d Sorensen
Krishna k Aryal
Karzan Abdulmuhsin Mohammad
Reza Assadi
Marcel Ausloos
Hayley d Tymeson
Leticia Avila-burgos
Tea Lallukka
Euripide f Avokpaho
Gessessew Bugssa Hailu
Ashish Awasthi
Joan b Soriano
Henok Tadesse Ayele
Mudavath Siva Durga Prasad Nayak
Mohammad Sadegh Rezai
Rakesh Ayer
Tambe b Ayuk
Peter s Azzopardi
Hamid Badali
Alaa Badawi
Maciej Banach
Hilton Lam
Chandrashekhar t Sreeramareddy
Vidhya Venkateswaran
Suzanne Lyn Barker-collo
Randah r Hamadeh
Leonardo Roever
Chakib Nejjari
Lope h Barrero
Huda Basaleem
Estifanos Baye
Shahrzad Bazargan-hejazi
Neeraj Bedi
Barthelemy Kuate Defo
Yannick Béjot
Abate Bekele Belachew
Faris Hasan Lami
Saba Abraham Belay
Luca Ronfani
Derrick a Bennett
Subas Neupane
Austin Douglas Tapp
Samer Hamidi
Isabela m Bensenor
Azmeraw t Amare
Eduardo Bernabe
Robert s Bernstein
Addisu Shunu Beyene
Tina Beyranvand
Soumyadeeep Bhaumik
Robin Room
Qing Lan
Zulfiqar a Bhutta
Jagdish Khubchandani
Belete Biadgo
Nadine Steckling
Ali Bijani
Nigus Bililign
Graeme j Hankey
Mohammad h Forouzanfar
Sait Mentes Birlik
Charles Birungi
Gholamreza Roshandel
Hailemichael Bizuneh
Peter Bjerregaard
Justin j Lang
Dan j Stein
Lilian a Ghandour
Tone Bjørge
Guilherme Borges
Cristina Bosetti
Soufiane Boufous
Nicola Luigi Bragazzi
Hilda l Harb
Ali Rostami
Hermann Brenner
Max Ggriswold
Satinath Mukhopadhyay
Joseph s Salama
Zahid a Butt
Sudan Prasad Neupane
Sutapa Agrawal
Lucero Cahuana-hurtado
Bianca Calabria
Ismael r Campos-nonato
Julio Cesar Campuzano
Gregory a Roth
Giulia Carreras
Saleem m Rana
Juan j Carrero
Sivadasanpillai Harikrishnan
Félix Carvalho
Carlos a Castañeda-orjuela
Josephine w Ngunjiri
Jacqueline Castillo Rivas
Sonia Lansky
Kalkidan Hassen Abate
Ferrán Catalá-lópez
Mohammed Mehdi Abrar
Rahul Gupta
Jung-chen Chang
Fiona j Charlson
Aparajita Chattopadhyay
Pankaj Chaturvedi
Rajiv Chowdhury
Josep Maria Haro
Cuong Tat Nguyen
Devasahayam j Christopher
Sheng-chia Chung
Anders o Larsson
Mu'awiyyah Babale Sufiyan
Ambuj Roy
Liliana g Ciobanu
Rafael Moreira Claro
Degu Abate
Sara Conti
Ewerton Cousin
Michael h Criqui
Berihun Assefa Dachew
Long Hoang Nguyen
Paul i Dargan
Patrick j Sur
Hamid Yimam Hassen
Nicholas Arian
Ahmad Daryani
Morsaleh Ganji
José Das Neves
Kairat Davletov
Filipa de Castro
Barbora de Courten
Solomon m Abay
Jan-walter de Neve
Bryan l Sykes
Trang Huyen Nguyen
Louisa Degenhardt
Noushin Mohammadifard
Gebre Teklemariam Demoz
Don c Des Jarlais
Nancy Fullman
Arman Latifi
Subhojit Dey
Rupinder Singh Dhaliwal
Samath Dhamminda Dharmaratne
Rafael Tabarés-seisdedos
Meghnath Dhimal
David Teye Doku
Fares Alahdab
Sonali Kochhar
Kerrie e Doyle
Cristiana Abbafati
Manisha Dubey
Eleonora Dubljanin
Bruce b Duncan
Janet l Leasher
Takahiro Tabuchi
Olatunji o Adetokunboh
Hedyeh Ebrahimi
Dumessa Edessa
Maysaa el Sayed Zaki
Mehran Alijanzadeh
Dina Nur Anggraini Ningrum
Sergei Petrovich Ermakov
Holly e Erskine
Alireza Esteghamati
Mahbobeh Faramarzi
Mohammad Tavakkoli
Rizwan Suliankatchi Abdulkader
Andrea Farioli
Paul h Lee
Andre Faro
Rasmus Havmoeller
Yogesh Damodar Sabde
Maryam s Farvid
Yirga Legesse Nirayo
Farshad Farzadfar
Valery l Feigin
Burcu Kucuk Bicer
Simon i Hay
Behzad Heibati
Andualem Henok
Ileana Heredia-pi
Norberto Francisco Hernández-llanes
James Leigh
Basema Saddik
Claudiu Herteliu
Desalegn ts Tsegaw Hibstu
Jean Jacques Noubiap
Arash Tehrani-banihashemi
Praveen Hoogar
Nobuyuki Horita
Tara Ballav Adhikari
h Dean Hosgood
Mostafa Hosseini
Mihaela Hostiuc
Guoqing hu
Saeid Safiri
Hsiang Huang
Mall Leinsalu
Merhawi Gebremedhin Tekle
Abdullatif Husseini
Cho-il Kim
Bulat Idrisov
Bogdan Vasile Ileanu
Olayinka Stephen Ilesanmi
Seyed Sina Naghibi Irvani
Jose c Adsuar
Sheikh Mohammed Shariful Islam
Amirhossein Sahebkar
Maria d Jackson
Chhabi Lal Ranabhat
Mihajlo Jakovljevic
Moti Tolera Jalu
Janni Leung
Richard Ofori-asenso
Achala Upendra Jayatilleke
Ravi Prakash Jha
Jost b Jonas
Jacek Jerzy Jozwiak
Zubair Kabir
Reza Ghadimi
Rajendra Kadel
Mohsen Afarideh
Amaha Kahsay
Umesh Kapil
Amir Kasaeian
Mamata Ghimire
Miriam Levi
Tesfaye d Dessale Kassa
Srinivasa Vittal Katikireddi
Norito Kawakami
Leopold n Aminde
Zikria Saleem
Seifu Kebede
Adane Teshome Kefale
Peter Njenga Keiyoro
Andre Pascal Kengne
Emilie Elisabet Agardh
Yousef Khader
Felix Akpojene Ogbo
Morteza Abdullatif Khafaie
Yichong li
Subash Thapa
Ibrahim a Khalil
Joshua a Salomon
md Nuruzzaman Khan
Young-ho Khang
Muktar Beshir Ahmed
Lee-ling Lim
Fortune Gbetoho Gankpe
Shai Linn
Shiwei Liu
In-hwan oh
Rajeev Gupta
Andrea Lobato-cordero
Alan d Lopez
Carolyn c Gotay
Paulo a Lotufo
Erlyn Rachelle King Macarayan
Isis Eloah Machado
Fabiana Madotto
Hassan Magdy Abd el Razek
Mohammed Akibu
Gebremedhin Berhe Gebregergs
Nihal Thomas
Muhammed Magdy Abd el Razek
Olanrewaju Oladimeji
Marek Majdan
Deena h al Asfoor
Reza Majdzadeh
Azeem Majeed
Reza Malekzadeh
Deborah Carvalho Malta
Chabila Christopher Mapoma
Jose Martinez-raga
Roman Topor-madry
Pallab k Maulik
Mohsen Mazidi
Victor Aboyans
Andrew t Olagunju
Sundeep Santosh Salvi
Caitlin Hawley
Tomi Akinyemiju
Martin Mckee
Varshil Mehta
Toni Meier
Fotis Topouzis
Tesfa Mekonen
Kidanu Gebremariam Meles
Addisu Melese
Peter t n Memiah
Walter Mendoza
Neal d Futran
Pedro r Olivares
Tsegaye Tewelde Gebrehiwot
Desalegn Tadese Mengistu
George a Mensah
Bach Xuan Tran
Nadia Akseer
Tuomo j Meretoja
Haftay Berhane Mezgebe
Tomasz Miazgowski
Ted r Miller
gk Mini
Juan Sanabria
Andreea Mirica
Bolajoko Olubukunola Olusanya
Erkin m Mirrakhimov
Christopher e Troeger
Johanna m Geleijnse
Babak Moazen
Khurshid Alam
Jacob Olusegun Olusanya
Daniel Kim
Anu Mary Oommen
Eyal Oren
Maria Dolores Sanchez-niño
Paramjit Singh Gill
Heather m Orpana
Sargis Aghasi Aghayan
Doris d v Ortega-altamirano
Justin r Ortiz
Erika Ota
Mayowa Ojo Owolabi
Abayomi Samuel Oyekale
Mahesh p a
Yun Jin Kim
Ammar Albujeer
Syed Mohamed Aljunid
Adrian Pana
David Laith Rawaf
Eun-kee Park
Ibrahim Abdelmageed Ginawi
Charles d h Parry
Hadi Parsian
Ajay Patle
George c Patton
Deepak Paudel
Max Petzold
Gina Agarwal
Damian Francesco Santomauro
Thomas Clement Truelsen
Michael r Phillips
Julian David Pillay
Kefyalew Addis Alene
Maarten j Postma
Ababi Zergaw z Giref
Farshad Pourmalek
Dorairaj Prabhakaran
Mostafa Qorbani
Amir Radfar
Anwar Rafay
Mona m Khater
Itamar s Santos
Ruth w Kimokoti
Alireza Rafiei
Fakher Rahim
Afarin Rahimi-movaghar
Mahfuzar Rahman
Raghib Ali
Philimon n Gona
Muhammad Aziz Rahman
Rajesh Kumar Rai
Nikolaos Tsilimparis
Sasa Rajsic
Milena m m Santric Milicevic
Sree Bhushan Raju
Adnan Kisa
Usha Ram
Abdur Razzaque Sarker
Rodrigo Sarmiento-suárez
Shafiu Mohammed
Nizal Sarrafzadegan
Alessandra c Goulart
Stefanos Tyrovolas
Soewarta Kosen
Benn Sartorius
Maheswar Satpathy
Monika Sawhney
Sonia Saxena
Ala'a Alkerwi
Mete Saylan
Michael p Schaub
Lorenzo Monasta
Maria Inês Schmidt
Kingsley Nnanna Ukwaja
Ione j c Schneider
Ben Schöttker
Parvaiz a Koul
Felix Greaves
Aletta Elisabeth Schutte
Falk Schwendicke
Sadaf g Sepanlou
Masood Ali Shaikh
Mehdi Sharif
Paula Moraga
Walid Ammar
Peter Allebeck
Jun She
Aziz Sheikh
Jiabin Shen
ai Koyanagi
Mekonnen Sisay Shiferaw
Giuseppe Grosso
Mika Shigematsu
Rahman Shiri
Kawkab Shishani
Vipin Gupta
Lidia Morawska
Ivy Shiue
Sharvari Rahul Shukla
Inga Dora Sigfusdottir
Nelson Alvis-guzman
Diego Augusto Santos Silva
Kewal Krishan
Natacha Torres da Silva
Dayane Gabriele Alves Silveira
Yuming Guo
Irfan Ullah
Dhirendra Narain Sinha
Seyyed Meysam Mousavi
Freddy Sitas
Olalekan a Uthman
Pascual r Valdez
Salman Rawaf
Job f m Van Boven
Veena s Kulkarni
Kamarul Imran Musa
Tommi Juhani Vasankari
Narayanaswamy Venketasubramanian
Francesco s Violante
Sergey Konstantinovitch Vladimirov
Vasily Vlassov
Stein Emil Vollset
Reyna Alma Gutiérrez
Robert c Reiner
Yaw Ampem Amoako
Theo Vos
Fasil Wagnew Shiferaw Wagnew
Aliya Naheed
Pushpendra Kumar
Yasir Waheed
Yuan-pang Wang
Elisabete Weiderpass
Fitsum Weldegebreal
Kidu Gidey Weldegwergs
Sameer Vali Gopalani
Andrea Werdecker
Ronny Westerman
Murthy Gvs
Harvey a Whiteford
Gurudatta Naik
Gianna Gayle Herrera Amul
Alessandra Lafranconi
Justyna Widecka
Tissa Wijeratne
Grant m a Wyper
Syed Danish Ali
Gelin xu
Tomohide Yamada
Yuichiro Yano
Pengpeng ye
Ebrahim m Yimer
Farid Najafi
Pawan Acharya
Paul Yip
Silvano Gallus
Biruck Desalegn Yirsaw
Cesar Reis
Stephanie r m Zimsen
author_role author
author2 Eduarda Fernandes
Alize j Ferrari
Cleusa p Ferri
Daniel Obadare Fijabi
Zegeye Abebe
Irina Filip
Jonas David Finger
Florian Fischer
Abraham d Flaxman
Richard Charles Franklin
Catalina Liliana Andrei
Engida Yisma
Naohiro Yonemoto
Seok-jun Yoon
Marcel Yotebieng
Ziyad Al-aly
Mustafa z Younis
Geevar Zachariah
Nima Hafezi-nejad
Andre m n Renzaho
Adauto Martins Soares Filho
Arjun Lakshmana Balaji
Zoubida Zaidi
Mohammad Zamani
Xueying Zhang
Sanjay Zodpey
Colin Angus
Ali h Mokdad
Vinay Nangia
Mohsen Naghavi
Christopher j l Murray
Moslem Soofi
Mika Kivimäki
Emmanuela Gakidou
Mustafa Geleto Ansha
Ratilal Lalloo
Tekleberhan Beyene Hagos
Carl Abelardo t Antonio
Olatunde Aremu
Johan Ärnlöv
al Artaman
Jobert Richie Nansseu
Reed j d Sorensen
Krishna k Aryal
Karzan Abdulmuhsin Mohammad
Reza Assadi
Marcel Ausloos
Hayley d Tymeson
Leticia Avila-burgos
Tea Lallukka
Euripide f Avokpaho
Gessessew Bugssa Hailu
Ashish Awasthi
Joan b Soriano
Henok Tadesse Ayele
Mudavath Siva Durga Prasad Nayak
Mohammad Sadegh Rezai
Rakesh Ayer
Tambe b Ayuk
Peter s Azzopardi
Hamid Badali
Alaa Badawi
Maciej Banach
Hilton Lam
Chandrashekhar t Sreeramareddy
Vidhya Venkateswaran
Suzanne Lyn Barker-collo
Randah r Hamadeh
Leonardo Roever
Chakib Nejjari
Lope h Barrero
Huda Basaleem
Estifanos Baye
Shahrzad Bazargan-hejazi
Neeraj Bedi
Barthelemy Kuate Defo
Yannick Béjot
Abate Bekele Belachew
Faris Hasan Lami
Saba Abraham Belay
Luca Ronfani
Derrick a Bennett
Subas Neupane
Austin Douglas Tapp
Samer Hamidi
Isabela m Bensenor
Azmeraw t Amare
Eduardo Bernabe
Robert s Bernstein
Addisu Shunu Beyene
Tina Beyranvand
Soumyadeeep Bhaumik
Robin Room
Qing Lan
Zulfiqar a Bhutta
Jagdish Khubchandani
Belete Biadgo
Nadine Steckling
Ali Bijani
Nigus Bililign
Graeme j Hankey
Mohammad h Forouzanfar
Sait Mentes Birlik
Charles Birungi
Gholamreza Roshandel
Hailemichael Bizuneh
Peter Bjerregaard
Justin j Lang
Dan j Stein
Lilian a Ghandour
Tone Bjørge
Guilherme Borges
Cristina Bosetti
Soufiane Boufous
Nicola Luigi Bragazzi
Hilda l Harb
Ali Rostami
Hermann Brenner
Max Ggriswold
Satinath Mukhopadhyay
Joseph s Salama
Zahid a Butt
Sudan Prasad Neupane
Sutapa Agrawal
Lucero Cahuana-hurtado
Bianca Calabria
Ismael r Campos-nonato
Julio Cesar Campuzano
Gregory a Roth
Giulia Carreras
Saleem m Rana
Juan j Carrero
Sivadasanpillai Harikrishnan
Félix Carvalho
Carlos a Castañeda-orjuela
Josephine w Ngunjiri
Jacqueline Castillo Rivas
Sonia Lansky
Kalkidan Hassen Abate
Ferrán Catalá-lópez
Mohammed Mehdi Abrar
Rahul Gupta
Jung-chen Chang
Fiona j Charlson
Aparajita Chattopadhyay
Pankaj Chaturvedi
Rajiv Chowdhury
Josep Maria Haro
Cuong Tat Nguyen
Devasahayam j Christopher
Sheng-chia Chung
Anders o Larsson
Mu'awiyyah Babale Sufiyan
Ambuj Roy
Liliana g Ciobanu
Rafael Moreira Claro
Degu Abate
Sara Conti
Ewerton Cousin
Michael h Criqui
Berihun Assefa Dachew
Long Hoang Nguyen
Paul i Dargan
Patrick j Sur
Hamid Yimam Hassen
Nicholas Arian
Ahmad Daryani
Morsaleh Ganji
José Das Neves
Kairat Davletov
Filipa de Castro
Barbora de Courten
Solomon m Abay
Jan-walter de Neve
Bryan l Sykes
Trang Huyen Nguyen
Louisa Degenhardt
Noushin Mohammadifard
Gebre Teklemariam Demoz
Don c Des Jarlais
Nancy Fullman
Arman Latifi
Subhojit Dey
Rupinder Singh Dhaliwal
Samath Dhamminda Dharmaratne
Rafael Tabarés-seisdedos
Meghnath Dhimal
David Teye Doku
Fares Alahdab
Sonali Kochhar
Kerrie e Doyle
Cristiana Abbafati
Manisha Dubey
Eleonora Dubljanin
Bruce b Duncan
Janet l Leasher
Takahiro Tabuchi
Olatunji o Adetokunboh
Hedyeh Ebrahimi
Dumessa Edessa
Maysaa el Sayed Zaki
Mehran Alijanzadeh
Dina Nur Anggraini Ningrum
Sergei Petrovich Ermakov
Holly e Erskine
Alireza Esteghamati
Mahbobeh Faramarzi
Mohammad Tavakkoli
Rizwan Suliankatchi Abdulkader
Andrea Farioli
Paul h Lee
Andre Faro
Rasmus Havmoeller
Yogesh Damodar Sabde
Maryam s Farvid
Yirga Legesse Nirayo
Farshad Farzadfar
Valery l Feigin
Burcu Kucuk Bicer
Simon i Hay
Behzad Heibati
Andualem Henok
Ileana Heredia-pi
Norberto Francisco Hernández-llanes
James Leigh
Basema Saddik
Claudiu Herteliu
Desalegn ts Tsegaw Hibstu
Jean Jacques Noubiap
Arash Tehrani-banihashemi
Praveen Hoogar
Nobuyuki Horita
Tara Ballav Adhikari
h Dean Hosgood
Mostafa Hosseini
Mihaela Hostiuc
Guoqing hu
Saeid Safiri
Hsiang Huang
Mall Leinsalu
Merhawi Gebremedhin Tekle
Abdullatif Husseini
Cho-il Kim
Bulat Idrisov
Bogdan Vasile Ileanu
Olayinka Stephen Ilesanmi
Seyed Sina Naghibi Irvani
Jose c Adsuar
Sheikh Mohammed Shariful Islam
Amirhossein Sahebkar
Maria d Jackson
Chhabi Lal Ranabhat
Mihajlo Jakovljevic
Moti Tolera Jalu
Janni Leung
Richard Ofori-asenso
Achala Upendra Jayatilleke
Ravi Prakash Jha
Jost b Jonas
Jacek Jerzy Jozwiak
Zubair Kabir
Reza Ghadimi
Rajendra Kadel
Mohsen Afarideh
Amaha Kahsay
Umesh Kapil
Amir Kasaeian
Mamata Ghimire
Miriam Levi
Tesfaye d Dessale Kassa
Srinivasa Vittal Katikireddi
Norito Kawakami
Leopold n Aminde
Zikria Saleem
Seifu Kebede
Adane Teshome Kefale
Peter Njenga Keiyoro
Andre Pascal Kengne
Emilie Elisabet Agardh
Yousef Khader
Felix Akpojene Ogbo
Morteza Abdullatif Khafaie
Yichong li
Subash Thapa
Ibrahim a Khalil
Joshua a Salomon
md Nuruzzaman Khan
Young-ho Khang
Muktar Beshir Ahmed
Lee-ling Lim
Fortune Gbetoho Gankpe
Shai Linn
Shiwei Liu
In-hwan oh
Rajeev Gupta
Andrea Lobato-cordero
Alan d Lopez
Carolyn c Gotay
Paulo a Lotufo
Erlyn Rachelle King Macarayan
Isis Eloah Machado
Fabiana Madotto
Hassan Magdy Abd el Razek
Mohammed Akibu
Gebremedhin Berhe Gebregergs
Nihal Thomas
Muhammed Magdy Abd el Razek
Olanrewaju Oladimeji
Marek Majdan
Deena h al Asfoor
Reza Majdzadeh
Azeem Majeed
Reza Malekzadeh
Deborah Carvalho Malta
Chabila Christopher Mapoma
Jose Martinez-raga
Roman Topor-madry
Pallab k Maulik
Mohsen Mazidi
Victor Aboyans
Andrew t Olagunju
Sundeep Santosh Salvi
Caitlin Hawley
Tomi Akinyemiju
Martin Mckee
Varshil Mehta
Toni Meier
Fotis Topouzis
Tesfa Mekonen
Kidanu Gebremariam Meles
Addisu Melese
Peter t n Memiah
Walter Mendoza
Neal d Futran
Pedro r Olivares
Tsegaye Tewelde Gebrehiwot
Desalegn Tadese Mengistu
George a Mensah
Bach Xuan Tran
Nadia Akseer
Tuomo j Meretoja
Haftay Berhane Mezgebe
Tomasz Miazgowski
Ted r Miller
gk Mini
Juan Sanabria
Andreea Mirica
Bolajoko Olubukunola Olusanya
Erkin m Mirrakhimov
Christopher e Troeger
Johanna m Geleijnse
Babak Moazen
Khurshid Alam
Jacob Olusegun Olusanya
Daniel Kim
Anu Mary Oommen
Eyal Oren
Maria Dolores Sanchez-niño
Paramjit Singh Gill
Heather m Orpana
Sargis Aghasi Aghayan
Doris d v Ortega-altamirano
Justin r Ortiz
Erika Ota
Mayowa Ojo Owolabi
Abayomi Samuel Oyekale
Mahesh p a
Yun Jin Kim
Ammar Albujeer
Syed Mohamed Aljunid
Adrian Pana
David Laith Rawaf
Eun-kee Park
Ibrahim Abdelmageed Ginawi
Charles d h Parry
Hadi Parsian
Ajay Patle
George c Patton
Deepak Paudel
Max Petzold
Gina Agarwal
Damian Francesco Santomauro
Thomas Clement Truelsen
Michael r Phillips
Julian David Pillay
Kefyalew Addis Alene
Maarten j Postma
Ababi Zergaw z Giref
Farshad Pourmalek
Dorairaj Prabhakaran
Mostafa Qorbani
Amir Radfar
Anwar Rafay
Mona m Khater
Itamar s Santos
Ruth w Kimokoti
Alireza Rafiei
Fakher Rahim
Afarin Rahimi-movaghar
Mahfuzar Rahman
Raghib Ali
Philimon n Gona
Muhammad Aziz Rahman
Rajesh Kumar Rai
Nikolaos Tsilimparis
Sasa Rajsic
Milena m m Santric Milicevic
Sree Bhushan Raju
Adnan Kisa
Usha Ram
Abdur Razzaque Sarker
Rodrigo Sarmiento-suárez
Shafiu Mohammed
Nizal Sarrafzadegan
Alessandra c Goulart
Stefanos Tyrovolas
Soewarta Kosen
Benn Sartorius
Maheswar Satpathy
Monika Sawhney
Sonia Saxena
Ala'a Alkerwi
Mete Saylan
Michael p Schaub
Lorenzo Monasta
Maria Inês Schmidt
Kingsley Nnanna Ukwaja
Ione j c Schneider
Ben Schöttker
Parvaiz a Koul
Felix Greaves
Aletta Elisabeth Schutte
Falk Schwendicke
Sadaf g Sepanlou
Masood Ali Shaikh
Mehdi Sharif
Paula Moraga
Walid Ammar
Peter Allebeck
Jun She
Aziz Sheikh
Jiabin Shen
ai Koyanagi
Mekonnen Sisay Shiferaw
Giuseppe Grosso
Mika Shigematsu
Rahman Shiri
Kawkab Shishani
Vipin Gupta
Lidia Morawska
Ivy Shiue
Sharvari Rahul Shukla
Inga Dora Sigfusdottir
Nelson Alvis-guzman
Diego Augusto Santos Silva
Kewal Krishan
Natacha Torres da Silva
Dayane Gabriele Alves Silveira
Yuming Guo
Irfan Ullah
Dhirendra Narain Sinha
Seyyed Meysam Mousavi
Freddy Sitas
Olalekan a Uthman
Pascual r Valdez
Salman Rawaf
Job f m Van Boven
Veena s Kulkarni
Kamarul Imran Musa
Tommi Juhani Vasankari
Narayanaswamy Venketasubramanian
Francesco s Violante
Sergey Konstantinovitch Vladimirov
Vasily Vlassov
Stein Emil Vollset
Reyna Alma Gutiérrez
Robert c Reiner
Yaw Ampem Amoako
Theo Vos
Fasil Wagnew Shiferaw Wagnew
Aliya Naheed
Pushpendra Kumar
Yasir Waheed
Yuan-pang Wang
Elisabete Weiderpass
Fitsum Weldegebreal
Kidu Gidey Weldegwergs
Sameer Vali Gopalani
Andrea Werdecker
Ronny Westerman
Murthy Gvs
Harvey a Whiteford
Gurudatta Naik
Gianna Gayle Herrera Amul
Alessandra Lafranconi
Justyna Widecka
Tissa Wijeratne
Grant m a Wyper
Syed Danish Ali
Gelin xu
Tomohide Yamada
Yuichiro Yano
Pengpeng ye
Ebrahim m Yimer
Farid Najafi
Pawan Acharya
Paul Yip
Silvano Gallus
Biruck Desalegn Yirsaw
Cesar Reis
Stephanie r m Zimsen
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dc.contributor.author.fl_str_mv Mariana Santos Felisbino-mendes
Eduarda Fernandes
Alize j Ferrari
Cleusa p Ferri
Daniel Obadare Fijabi
Zegeye Abebe
Irina Filip
Jonas David Finger
Florian Fischer
Abraham d Flaxman
Richard Charles Franklin
Catalina Liliana Andrei
Engida Yisma
Naohiro Yonemoto
Seok-jun Yoon
Marcel Yotebieng
Ziyad Al-aly
Mustafa z Younis
Geevar Zachariah
Nima Hafezi-nejad
Andre m n Renzaho
Adauto Martins Soares Filho
Arjun Lakshmana Balaji
Zoubida Zaidi
Mohammad Zamani
Xueying Zhang
Sanjay Zodpey
Colin Angus
Ali h Mokdad
Vinay Nangia
Mohsen Naghavi
Christopher j l Murray
Moslem Soofi
Mika Kivimäki
Emmanuela Gakidou
Mustafa Geleto Ansha
Ratilal Lalloo
Tekleberhan Beyene Hagos
Carl Abelardo t Antonio
Olatunde Aremu
Johan Ärnlöv
al Artaman
Jobert Richie Nansseu
Reed j d Sorensen
Krishna k Aryal
Karzan Abdulmuhsin Mohammad
Reza Assadi
Marcel Ausloos
Hayley d Tymeson
Leticia Avila-burgos
Tea Lallukka
Euripide f Avokpaho
Gessessew Bugssa Hailu
Ashish Awasthi
Joan b Soriano
Henok Tadesse Ayele
Mudavath Siva Durga Prasad Nayak
Mohammad Sadegh Rezai
Rakesh Ayer
Tambe b Ayuk
Peter s Azzopardi
Hamid Badali
Alaa Badawi
Maciej Banach
Hilton Lam
Chandrashekhar t Sreeramareddy
Vidhya Venkateswaran
Suzanne Lyn Barker-collo
Randah r Hamadeh
Leonardo Roever
Chakib Nejjari
Lope h Barrero
Huda Basaleem
Estifanos Baye
Shahrzad Bazargan-hejazi
Neeraj Bedi
Barthelemy Kuate Defo
Yannick Béjot
Abate Bekele Belachew
Faris Hasan Lami
Saba Abraham Belay
Luca Ronfani
Derrick a Bennett
Subas Neupane
Austin Douglas Tapp
Samer Hamidi
Isabela m Bensenor
Azmeraw t Amare
Eduardo Bernabe
Robert s Bernstein
Addisu Shunu Beyene
Tina Beyranvand
Soumyadeeep Bhaumik
Robin Room
Qing Lan
Zulfiqar a Bhutta
Jagdish Khubchandani
Belete Biadgo
Nadine Steckling
Ali Bijani
Nigus Bililign
Graeme j Hankey
Mohammad h Forouzanfar
Sait Mentes Birlik
Charles Birungi
Gholamreza Roshandel
Hailemichael Bizuneh
Peter Bjerregaard
Justin j Lang
Dan j Stein
Lilian a Ghandour
Tone Bjørge
Guilherme Borges
Cristina Bosetti
Soufiane Boufous
Nicola Luigi Bragazzi
Hilda l Harb
Ali Rostami
Hermann Brenner
Max Ggriswold
Satinath Mukhopadhyay
Joseph s Salama
Zahid a Butt
Sudan Prasad Neupane
Sutapa Agrawal
Lucero Cahuana-hurtado
Bianca Calabria
Ismael r Campos-nonato
Julio Cesar Campuzano
Gregory a Roth
Giulia Carreras
Saleem m Rana
Juan j Carrero
Sivadasanpillai Harikrishnan
Félix Carvalho
Carlos a Castañeda-orjuela
Josephine w Ngunjiri
Jacqueline Castillo Rivas
Sonia Lansky
Kalkidan Hassen Abate
Ferrán Catalá-lópez
Mohammed Mehdi Abrar
Rahul Gupta
Jung-chen Chang
Fiona j Charlson
Aparajita Chattopadhyay
Pankaj Chaturvedi
Rajiv Chowdhury
Josep Maria Haro
Cuong Tat Nguyen
Devasahayam j Christopher
Sheng-chia Chung
Anders o Larsson
Mu'awiyyah Babale Sufiyan
Ambuj Roy
Liliana g Ciobanu
Rafael Moreira Claro
Degu Abate
Sara Conti
Ewerton Cousin
Michael h Criqui
Berihun Assefa Dachew
Long Hoang Nguyen
Paul i Dargan
Patrick j Sur
Hamid Yimam Hassen
Nicholas Arian
Ahmad Daryani
Morsaleh Ganji
José Das Neves
Kairat Davletov
Filipa de Castro
Barbora de Courten
Solomon m Abay
Jan-walter de Neve
Bryan l Sykes
Trang Huyen Nguyen
Louisa Degenhardt
Noushin Mohammadifard
Gebre Teklemariam Demoz
Don c Des Jarlais
Nancy Fullman
Arman Latifi
Subhojit Dey
Rupinder Singh Dhaliwal
Samath Dhamminda Dharmaratne
Rafael Tabarés-seisdedos
Meghnath Dhimal
David Teye Doku
Fares Alahdab
Sonali Kochhar
Kerrie e Doyle
Cristiana Abbafati
Manisha Dubey
Eleonora Dubljanin
Bruce b Duncan
Janet l Leasher
Takahiro Tabuchi
Olatunji o Adetokunboh
Hedyeh Ebrahimi
Dumessa Edessa
Maysaa el Sayed Zaki
Mehran Alijanzadeh
Dina Nur Anggraini Ningrum
Sergei Petrovich Ermakov
Holly e Erskine
Alireza Esteghamati
Mahbobeh Faramarzi
Mohammad Tavakkoli
Rizwan Suliankatchi Abdulkader
Andrea Farioli
Paul h Lee
Andre Faro
Rasmus Havmoeller
Yogesh Damodar Sabde
Maryam s Farvid
Yirga Legesse Nirayo
Farshad Farzadfar
Valery l Feigin
Burcu Kucuk Bicer
Simon i Hay
Behzad Heibati
Andualem Henok
Ileana Heredia-pi
Norberto Francisco Hernández-llanes
James Leigh
Basema Saddik
Claudiu Herteliu
Desalegn ts Tsegaw Hibstu
Jean Jacques Noubiap
Arash Tehrani-banihashemi
Praveen Hoogar
Nobuyuki Horita
Tara Ballav Adhikari
h Dean Hosgood
Mostafa Hosseini
Mihaela Hostiuc
Guoqing hu
Saeid Safiri
Hsiang Huang
Mall Leinsalu
Merhawi Gebremedhin Tekle
Abdullatif Husseini
Cho-il Kim
Bulat Idrisov
Bogdan Vasile Ileanu
Olayinka Stephen Ilesanmi
Seyed Sina Naghibi Irvani
Jose c Adsuar
Sheikh Mohammed Shariful Islam
Amirhossein Sahebkar
Maria d Jackson
Chhabi Lal Ranabhat
Mihajlo Jakovljevic
Moti Tolera Jalu
Janni Leung
Richard Ofori-asenso
Achala Upendra Jayatilleke
Ravi Prakash Jha
Jost b Jonas
Jacek Jerzy Jozwiak
Zubair Kabir
Joseph s Salama
Reza Ghadimi
Rajendra Kadel
Mohsen Afarideh
Amaha Kahsay
Umesh Kapil
Amir Kasaeian
Mamata Ghimire
Miriam Levi
Tesfaye d Dessale Kassa
Srinivasa Vittal Katikireddi
Norito Kawakami
Leopold n Aminde
Zikria Saleem
Seifu Kebede
Adane Teshome Kefale
Peter Njenga Keiyoro
Andre Pascal Kengne
Emilie Elisabet Agardh
Yousef Khader
Felix Akpojene Ogbo
Morteza Abdullatif Khafaie
Yichong li
Subash Thapa
Ibrahim a Khalil
Joshua a Salomon
md Nuruzzaman Khan
Young-ho Khang
Muktar Beshir Ahmed
Lee-ling Lim
Fortune Gbetoho Gankpe
Shai Linn
Shiwei Liu
In-hwan oh
Rajeev Gupta
Andrea Lobato-cordero
Alan d Lopez
Carolyn c Gotay
Paulo a Lotufo
Erlyn Rachelle King Macarayan
Isis Eloah Machado
Fabiana Madotto
Hassan Magdy Abd el Razek
Mohammed Akibu
Gebremedhin Berhe Gebregergs
Nihal Thomas
Muhammed Magdy Abd el Razek
Olanrewaju Oladimeji
Marek Majdan
Deena h al Asfoor
Reza Majdzadeh
Azeem Majeed
Reza Malekzadeh
Deborah Carvalho Malta
Chabila Christopher Mapoma
Jose Martinez-raga
Roman Topor-madry
Pallab k Maulik
Mohsen Mazidi
Victor Aboyans
Andrew t Olagunju
Sundeep Santosh Salvi
Caitlin Hawley
Tomi Akinyemiju
Martin Mckee
Varshil Mehta
Toni Meier
Fotis Topouzis
Tesfa Mekonen
Kidanu Gebremariam Meles
Addisu Melese
Peter t n Memiah
Walter Mendoza
Neal d Futran
Pedro r Olivares
Tsegaye Tewelde Gebrehiwot
Desalegn Tadese Mengistu
George a Mensah
Bach Xuan Tran
Nadia Akseer
Tuomo j Meretoja
Haftay Berhane Mezgebe
Tomasz Miazgowski
Ted r Miller
gk Mini
Juan Sanabria
Andreea Mirica
Bolajoko Olubukunola Olusanya
Erkin m Mirrakhimov
Christopher e Troeger
Johanna m Geleijnse
Babak Moazen
Khurshid Alam
Jacob Olusegun Olusanya
Daniel Kim
Anu Mary Oommen
Eyal Oren
Maria Dolores Sanchez-niño
Paramjit Singh Gill
Heather m Orpana
Sargis Aghasi Aghayan
Doris d v Ortega-altamirano
Justin r Ortiz
Erika Ota
Mayowa Ojo Owolabi
Abayomi Samuel Oyekale
Mahesh p a
Yun Jin Kim
Ammar Albujeer
Syed Mohamed Aljunid
Adrian Pana
David Laith Rawaf
Eun-kee Park
Ibrahim Abdelmageed Ginawi
Charles d h Parry
Hadi Parsian
Ajay Patle
George c Patton
Deepak Paudel
Max Petzold
Gina Agarwal
Damian Francesco Santomauro
Thomas Clement Truelsen
Michael r Phillips
Julian David Pillay
Kefyalew Addis Alene
Maarten j Postma
Ababi Zergaw z Giref
Farshad Pourmalek
Dorairaj Prabhakaran
Mostafa Qorbani
Amir Radfar
Anwar Rafay
Mona m Khater
Itamar s Santos
Ruth w Kimokoti
Alireza Rafiei
Fakher Rahim
Afarin Rahimi-movaghar
Mahfuzar Rahman
Raghib Ali
Philimon n Gona
Muhammad Aziz Rahman
Rajesh Kumar Rai
Nikolaos Tsilimparis
Sasa Rajsic
Milena m m Santric Milicevic
Sree Bhushan Raju
Adnan Kisa
Usha Ram
Abdur Razzaque Sarker
Rodrigo Sarmiento-suárez
Shafiu Mohammed
Nizal Sarrafzadegan
Alessandra c Goulart
Stefanos Tyrovolas
Soewarta Kosen
Benn Sartorius
Maheswar Satpathy
Monika Sawhney
Sonia Saxena
Ala'a Alkerwi
Mete Saylan
Michael p Schaub
Lorenzo Monasta
Maria Inês Schmidt
Kingsley Nnanna Ukwaja
Ione j c Schneider
Ben Schöttker
Parvaiz a Koul
Felix Greaves
Aletta Elisabeth Schutte
Falk Schwendicke
Sadaf g Sepanlou
Masood Ali Shaikh
Mehdi Sharif
Paula Moraga
Walid Ammar
Peter Allebeck
Jun She
Aziz Sheikh
Jiabin Shen
ai Koyanagi
Mekonnen Sisay Shiferaw
Giuseppe Grosso
Mika Shigematsu
Rahman Shiri
Kawkab Shishani
Vipin Gupta
Lidia Morawska
Ivy Shiue
Sharvari Rahul Shukla
Inga Dora Sigfusdottir
Nelson Alvis-guzman
Diego Augusto Santos Silva
Kewal Krishan
Natacha Torres da Silva
Dayane Gabriele Alves Silveira
Yuming Guo
Irfan Ullah
Dhirendra Narain Sinha
Seyyed Meysam Mousavi
Freddy Sitas
Olalekan a Uthman
Pascual r Valdez
Salman Rawaf
Job f m Van Boven
Veena s Kulkarni
Kamarul Imran Musa
Tommi Juhani Vasankari
Narayanaswamy Venketasubramanian
Francesco s Violante
Sergey Konstantinovitch Vladimirov
Vasily Vlassov
Stein Emil Vollset
Reyna Alma Gutiérrez
Robert c Reiner
Yaw Ampem Amoako
Theo Vos
Fasil Wagnew Shiferaw Wagnew
Aliya Naheed
Pushpendra Kumar
Yasir Waheed
Yuan-pang Wang
Elisabete Weiderpass
Fitsum Weldegebreal
Kidu Gidey Weldegwergs
Sameer Vali Gopalani
Andrea Werdecker
Ronny Westerman
Murthy Gvs
Harvey a Whiteford
Gurudatta Naik
Gianna Gayle Herrera Amul
Alessandra Lafranconi
Justyna Widecka
Tissa Wijeratne
Grant m a Wyper
Syed Danish Ali
Gelin xu
Tomohide Yamada
Yuichiro Yano
Pengpeng ye
Ebrahim m Yimer
Farid Najafi
Pawan Acharya
Paul Yip
Silvano Gallus
Biruck Desalegn Yirsaw
Cesar Reis
Stephanie r m Zimsen
dc.subject.por.fl_str_mv Alcohol Abuse
Global Burden of Disease
Alcoolismo
Carga Global da Doença
topic Alcohol Abuse
Global Burden of Disease
Alcoolismo
Carga Global da Doença
description Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks perweek.Interpretation. Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that therisk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption.
publishDate 2018
dc.date.none.fl_str_mv 2018
2023-04-17T21:04:15Z
2023-04-17T21:04:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.1016/S0140-6736(18)31310-2
01406736
http://hdl.handle.net/1843/52085
https://orcid.org/0000-0002-8214-5734
url https://doi.org/10.1016/S0140-6736(18)31310-2
http://hdl.handle.net/1843/52085
https://orcid.org/0000-0002-8214-5734
identifier_str_mv 01406736
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv The Lancet
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA
ENF - DEPARTAMENTO DE NUTRIÇÃO
UFMG
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA
ENF - DEPARTAMENTO DE NUTRIÇÃO
UFMG
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv repositorio@ufmg.br
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