Guidelines for utility measurement for economic analysis: the brazilian policy

Detalhes bibliográficos
Autor(a) principal: Andrea Liborio Monteiro
Data de Publicação: 2022
Outros Autores: Aline Navega Biz, Augusto Afonso Guerra Júnior, Helena Cramer, Vania Canuto, Luciane Cruz, Marcia Pinto, Monica Viegas, Marisa Santos, Ricardo Fernandes, Ivan Zimmermann
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1016/j.vhri.2022.03.004
http://hdl.handle.net/1843/60100
Resumo: Introduction: Health-related quality of life is expressed in utilities, also referred to as utility estimates or parameters. Considerations about the source and type of utility values are especially important in a modeling context, where the lack of transparency, including the lack of a hierarchy for utility data sources, is a major issue to any estimation and can potentially compromise model reliability. Objectives: This document aims to present the first version of the Brazilian guidelines for utility measurement to support economic analysis. Methods: A virtual workshop and a modified Delphi panel with 10 health technology specialists followed a rapid evaluation of 110 technical documents and indexed publications. The recommendations are based on the proposition that has received the most votes, although contentious issues are addressed in the suggestion or discussion. The rationale for the final decision is included in the text. Results: The consensus includes 50 recommendations with the following topics: Transparency and Reliability, Model Design, Conditions Under Which Generic Questionnaires Are Not Sensible or Valid, Utility Evidence Hierarchy, Utility Data Searching, Modeling Utility Values, Extrapolating Quality Adjusted Life-Years for Models With Lifetime Horizons, Caregiver Utility, Utility Data Synthesis, Quality/Certainty of the Evidence, and Utility Estimates in End-of-Life Conditions. Conclusions: The goal of this project is to create unified national standards for using utility metrics in economic analysis in Brazil. This set of recommendations is not obligatory, but it is meant to serve as a guide and lead to the development of better and more transparent economic models in the country.
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spelling 2023-10-26T19:08:25Z2023-10-26T19:08:25Z2022316773https://doi.org/10.1016/j.vhri.2022.03.0042212-1099http://hdl.handle.net/1843/60100Introduction: Health-related quality of life is expressed in utilities, also referred to as utility estimates or parameters. Considerations about the source and type of utility values are especially important in a modeling context, where the lack of transparency, including the lack of a hierarchy for utility data sources, is a major issue to any estimation and can potentially compromise model reliability. Objectives: This document aims to present the first version of the Brazilian guidelines for utility measurement to support economic analysis. Methods: A virtual workshop and a modified Delphi panel with 10 health technology specialists followed a rapid evaluation of 110 technical documents and indexed publications. The recommendations are based on the proposition that has received the most votes, although contentious issues are addressed in the suggestion or discussion. The rationale for the final decision is included in the text. Results: The consensus includes 50 recommendations with the following topics: Transparency and Reliability, Model Design, Conditions Under Which Generic Questionnaires Are Not Sensible or Valid, Utility Evidence Hierarchy, Utility Data Searching, Modeling Utility Values, Extrapolating Quality Adjusted Life-Years for Models With Lifetime Horizons, Caregiver Utility, Utility Data Synthesis, Quality/Certainty of the Evidence, and Utility Estimates in End-of-Life Conditions. Conclusions: The goal of this project is to create unified national standards for using utility metrics in economic analysis in Brazil. This set of recommendations is not obligatory, but it is meant to serve as a guide and lead to the development of better and more transparent economic models in the country.Introdução: A qualidade de vida relacionada à saúde é expressa em utilidades, também denominadas estimativas ou parâmetros de utilidade. Considerações sobre a fonte e o tipo de valores de utilidade são especialmente importantes num contexto de modelagem, onde a falta de a transparência, incluindo a falta de uma hierarquia para fontes de dados de serviços públicos, é uma questão importante para qualquer estimativa e pode potencialmente comprometer a confiabilidade do modelo. Objetivos: Este documento tem como objetivo apresentar a primeira versão das diretrizes brasileiras de medição útil para apoiar análise econômica. Métodos: Um workshop virtual e um painel Delphi modificado com 10 especialistas em tecnologia da saúde seguiram uma avaliação rápida de 110 documentos técnicos e publicações indexadas. As recomendações baseiam-se na proposição que recebeu o maioria dos votos, embora questões controversas sejam abordadas na sugestão ou discussão. A justificativa para a decisão final é incluído no texto. Resultados: O consenso inclui 50 recomendações com os seguintes temas: Transparência e Confiabilidade, Design de Modelo, Condições sob as quais questionários genéricos não são sensatos ou válidos, hierarquia de evidências de serviços públicos, pesquisa de dados de serviços públicos, Modelagem de valores de utilidade, extrapolando anos de vida ajustados pela qualidade para modelos com horizontes de vida, utilidade do cuidador, utilidade Síntese de dados, qualidade/certeza da evidência e estimativas de utilidade em condições de fim de vida. Conclusões: O objetivo deste projeto é criar padrões nacionais unificados para o uso de métricas de utilidade na análise econômica em Brasil. Este conjunto de recomendações não é obrigatório, mas pretende servir de guia e conduzir ao desenvolvimento de melhores e modelos económicos mais transparentes no país.engUniversidade Federal de Minas GeraisUFMGBrasilFAR - DEPARTAMENTO DE FARMÁCIA SOCIALFCE - DEPARTAMENTO DE CIÊNCIAS ECONÔMICASValue in Health Regional IssuesQualidade de vidaSaúdeHealth economicsPublic healthPublic policyQuality-adjusted life-yearUtility.Guidelines for utility measurement for economic analysis: the brazilian policyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.sciencedirect.com/science/article/pii/S2212109922001030Andrea Liborio MonteiroAline Navega BizAugusto Afonso Guerra JúniorHelena CramerVania CanutoLuciane CruzMarcia PintoMonica ViegasMarisa SantosRicardo FernandesIvan Zimmermanninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/60100/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALGuidelines for Utility Measurement for Economic Analysis.pdfGuidelines for Utility Measurement for Economic Analysis.pdfapplication/pdf529904https://repositorio.ufmg.br/bitstream/1843/60100/2/Guidelines%20for%20Utility%20Measurement%20for%20Economic%20Analysis.pdf9471a562503f07334630d5fea21906e3MD521843/601002023-10-26 16:34:17.255oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-10-26T19:34:17Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Guidelines for utility measurement for economic analysis: the brazilian policy
title Guidelines for utility measurement for economic analysis: the brazilian policy
spellingShingle Guidelines for utility measurement for economic analysis: the brazilian policy
Andrea Liborio Monteiro
Health economics
Public health
Public policy
Quality-adjusted life-year
Utility.
Qualidade de vida
Saúde
title_short Guidelines for utility measurement for economic analysis: the brazilian policy
title_full Guidelines for utility measurement for economic analysis: the brazilian policy
title_fullStr Guidelines for utility measurement for economic analysis: the brazilian policy
title_full_unstemmed Guidelines for utility measurement for economic analysis: the brazilian policy
title_sort Guidelines for utility measurement for economic analysis: the brazilian policy
author Andrea Liborio Monteiro
author_facet Andrea Liborio Monteiro
Aline Navega Biz
Augusto Afonso Guerra Júnior
Helena Cramer
Vania Canuto
Luciane Cruz
Marcia Pinto
Monica Viegas
Marisa Santos
Ricardo Fernandes
Ivan Zimmermann
author_role author
author2 Aline Navega Biz
Augusto Afonso Guerra Júnior
Helena Cramer
Vania Canuto
Luciane Cruz
Marcia Pinto
Monica Viegas
Marisa Santos
Ricardo Fernandes
Ivan Zimmermann
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Andrea Liborio Monteiro
Aline Navega Biz
Augusto Afonso Guerra Júnior
Helena Cramer
Vania Canuto
Luciane Cruz
Marcia Pinto
Monica Viegas
Marisa Santos
Ricardo Fernandes
Ivan Zimmermann
dc.subject.por.fl_str_mv Health economics
Public health
Public policy
Quality-adjusted life-year
Utility.
topic Health economics
Public health
Public policy
Quality-adjusted life-year
Utility.
Qualidade de vida
Saúde
dc.subject.other.pt_BR.fl_str_mv Qualidade de vida
Saúde
description Introduction: Health-related quality of life is expressed in utilities, also referred to as utility estimates or parameters. Considerations about the source and type of utility values are especially important in a modeling context, where the lack of transparency, including the lack of a hierarchy for utility data sources, is a major issue to any estimation and can potentially compromise model reliability. Objectives: This document aims to present the first version of the Brazilian guidelines for utility measurement to support economic analysis. Methods: A virtual workshop and a modified Delphi panel with 10 health technology specialists followed a rapid evaluation of 110 technical documents and indexed publications. The recommendations are based on the proposition that has received the most votes, although contentious issues are addressed in the suggestion or discussion. The rationale for the final decision is included in the text. Results: The consensus includes 50 recommendations with the following topics: Transparency and Reliability, Model Design, Conditions Under Which Generic Questionnaires Are Not Sensible or Valid, Utility Evidence Hierarchy, Utility Data Searching, Modeling Utility Values, Extrapolating Quality Adjusted Life-Years for Models With Lifetime Horizons, Caregiver Utility, Utility Data Synthesis, Quality/Certainty of the Evidence, and Utility Estimates in End-of-Life Conditions. Conclusions: The goal of this project is to create unified national standards for using utility metrics in economic analysis in Brazil. This set of recommendations is not obligatory, but it is meant to serve as a guide and lead to the development of better and more transparent economic models in the country.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-10-26T19:08:25Z
dc.date.available.fl_str_mv 2023-10-26T19:08:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/60100
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.1016/j.vhri.2022.03.004
dc.identifier.issn.pt_BR.fl_str_mv 2212-1099
url https://doi.org/10.1016/j.vhri.2022.03.004
http://hdl.handle.net/1843/60100
identifier_str_mv 2212-1099
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Value in Health Regional Issues
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv FAR - DEPARTAMENTO DE FARMÁCIA SOCIAL
FCE - DEPARTAMENTO DE CIÊNCIAS ECONÔMICAS
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
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