Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | https://doi.org/10.1590/S1806-37562017000000035 http://hdl.handle.net/1843/39996 |
Resumo: | Objective: To analyze mortality from idiopathic pulmonary fibrosis (IPF) in Brazil over the period 1979-2014. Methods: Microdata were extracted from the Brazilian National Ministry of Health Mortality Database. Only deaths for which the underlying cause was coded as International Classification of Diseases version 9 (ICD-9) 515 or 516.3 (until 1995) or as ICD version 10 (ICD-10) J84.1 (from 1996 onward) were included in our analysis. Standardized mortality rates were calculated for the 2010 Brazilian population. The annual trend in mortality rates was analyzed by joinpoint regression. We calculated risk ratios (RRs) by age group, time period of death, and gender, using a person-years denominator. Results: A total of 32,092 deaths were recorded in the study period. Standardized mortality rates trended upward, rising from 0.24/100,000 population in 1979 to 1.10/100,000 population in 2014. The annual upward trend in mortality rates had two inflection points, in 1992 and 2008, separating three distinct time segments with an annual growth of 2.2%, 6.8%, and 2.4%, respectively. The comparison of RRs for the age groups, using the 50- to 54-year age group as a reference, and for the study period, using 1979-1984 as a reference, were 16.14 (14.44-16.36) and 6.71 (6.34-7.12), respectively. Men compared with women had higher standardized mortality rates (per 100,000 person-years) in all age groups. Conclusion: Brazilian IPF mortality rates are lower than those of other countries, suggesting underdiagnosis or underreporting. The temporal trend is similar to those reported in the literature and is not explained solely by population aging. |
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2022-03-11T16:36:54Z2022-03-11T16:36:54Z2017436445450https://doi.org/10.1590/S1806-375620170000000351806-3756http://hdl.handle.net/1843/39996Objective: To analyze mortality from idiopathic pulmonary fibrosis (IPF) in Brazil over the period 1979-2014. Methods: Microdata were extracted from the Brazilian National Ministry of Health Mortality Database. Only deaths for which the underlying cause was coded as International Classification of Diseases version 9 (ICD-9) 515 or 516.3 (until 1995) or as ICD version 10 (ICD-10) J84.1 (from 1996 onward) were included in our analysis. Standardized mortality rates were calculated for the 2010 Brazilian population. The annual trend in mortality rates was analyzed by joinpoint regression. We calculated risk ratios (RRs) by age group, time period of death, and gender, using a person-years denominator. Results: A total of 32,092 deaths were recorded in the study period. Standardized mortality rates trended upward, rising from 0.24/100,000 population in 1979 to 1.10/100,000 population in 2014. The annual upward trend in mortality rates had two inflection points, in 1992 and 2008, separating three distinct time segments with an annual growth of 2.2%, 6.8%, and 2.4%, respectively. The comparison of RRs for the age groups, using the 50- to 54-year age group as a reference, and for the study period, using 1979-1984 as a reference, were 16.14 (14.44-16.36) and 6.71 (6.34-7.12), respectively. Men compared with women had higher standardized mortality rates (per 100,000 person-years) in all age groups. Conclusion: Brazilian IPF mortality rates are lower than those of other countries, suggesting underdiagnosis or underreporting. The temporal trend is similar to those reported in the literature and is not explained solely by population aging.Objetivo: Analisar a mortalidade por fibrose pulmonar idiopática (FPI) no Brasil ao longo período 1979-2014. Métodos: Os microdados foram extraídos do National National Banco de Dados de Mortalidade do Ministério da Saúde. Apenas os óbitos cuja causa básica foi codificado como Classificação Internacional de Doenças versão 9 (CID-9) 515 ou 516.3 (até 1995) ou como CID versão 10 (CID-10) J84.1 (de 1996 em diante) foram incluídos em nosso análise. As taxas de mortalidade padronizadas foram calculadas para a população brasileira de 2010. A tendência anual das taxas de mortalidade foi analisada por regressão joinpoint. Nós calculamos razões de risco (RRs) por faixa etária, período de tempo da morte e sexo, usando uma pessoa-ano denominador. Resultados: Foram registrados 32.092 óbitos no período do estudo. As taxas de mortalidade padronizadas apresentaram tendência ascendente, passando de 0,24/100.000 habitantes em 1979 para 1,10/100.000 habitantes em 2014. A tendência anual de aumento das taxas de mortalidade teve dois pontos de inflexão, em 1992 e 2008, separando três segmentos temporais distintos com crescimento anual de 2,2%, 6,8% e 2,4%, respectivamente. A comparação de RR para as faixas etárias, tendo como referência a faixa etária de 50 a 54 anos, e para o estudo período, usando 1979-1984 como referência, foram 16,14 (14,44-16,36) e 6,71 (6,34-7,12), respectivamente. Homens comparados com mulheres apresentaram taxas de mortalidade padronizadas mais altas (por 100.000 pessoas-ano) em todas as faixas etárias. Conclusão: As taxas brasileiras de mortalidade por FPI são inferiores aos de outros países, sugerindo subdiagnóstico ou subnotificação. O tendência temporal é semelhante às relatadas na literatura e não é explicada apenas por envelhecimento da população.engUniversidade Federal de Minas GeraisUFMGBrasilMEDICINA - FACULDADE DE MEDICINAJornal brasileiro de pneumologiaFibrose pulmonar idiopática/epidemiologiaFibrose pulmonar idiopática/mortalidadeDinâmica populacionalMortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014Mortalidade por fibrose pulmonar idiopática: uma análise de tendência temporal no Brasil, 1979-2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.scielo.br/j/jbpneu/a/xGLZdjksY3NVqkg8B5sNKQt/EduardoalgrantiCézar Akiyoshi SaitoDiego Rodrigues Mendonça e SilvaAna Paula Scalia CarneiroMarco Antonio Bussacosapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/39996/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINAL2017_Mortality from idiopathic pulmonary fibrosis- a temporal trend analysis in Brazil, 1979-2014.pdf2017_Mortality from idiopathic pulmonary fibrosis- a temporal trend analysis in Brazil, 1979-2014.pdfapplication/pdf363071https://repositorio.ufmg.br/bitstream/1843/39996/2/2017_Mortality%20from%20idiopathic%20pulmonary%20fibrosis-%20a%20temporal%20trend%20analysis%20in%20Brazil%2c%201979-2014.pdf30d5357b9cdae7fcf03f636fea31200cMD521843/399962022-03-11 13:36:54.991oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2022-03-11T16:36:54Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.pt_BR.fl_str_mv |
Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014 |
dc.title.alternative.pt_BR.fl_str_mv |
Mortalidade por fibrose pulmonar idiopática: uma análise de tendência temporal no Brasil, 1979-2014 |
title |
Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014 |
spellingShingle |
Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014 Eduardoalgranti Fibrose pulmonar idiopática/epidemiologia Fibrose pulmonar idiopática/mortalidade Dinâmica populacional |
title_short |
Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014 |
title_full |
Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014 |
title_fullStr |
Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014 |
title_full_unstemmed |
Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014 |
title_sort |
Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014 |
author |
Eduardoalgranti |
author_facet |
Eduardoalgranti Cézar Akiyoshi Saito Diego Rodrigues Mendonça e Silva Ana Paula Scalia Carneiro Marco Antonio Bussacos |
author_role |
author |
author2 |
Cézar Akiyoshi Saito Diego Rodrigues Mendonça e Silva Ana Paula Scalia Carneiro Marco Antonio Bussacos |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Eduardoalgranti Cézar Akiyoshi Saito Diego Rodrigues Mendonça e Silva Ana Paula Scalia Carneiro Marco Antonio Bussacos |
dc.subject.other.pt_BR.fl_str_mv |
Fibrose pulmonar idiopática/epidemiologia Fibrose pulmonar idiopática/mortalidade Dinâmica populacional |
topic |
Fibrose pulmonar idiopática/epidemiologia Fibrose pulmonar idiopática/mortalidade Dinâmica populacional |
description |
Objective: To analyze mortality from idiopathic pulmonary fibrosis (IPF) in Brazil over the period 1979-2014. Methods: Microdata were extracted from the Brazilian National Ministry of Health Mortality Database. Only deaths for which the underlying cause was coded as International Classification of Diseases version 9 (ICD-9) 515 or 516.3 (until 1995) or as ICD version 10 (ICD-10) J84.1 (from 1996 onward) were included in our analysis. Standardized mortality rates were calculated for the 2010 Brazilian population. The annual trend in mortality rates was analyzed by joinpoint regression. We calculated risk ratios (RRs) by age group, time period of death, and gender, using a person-years denominator. Results: A total of 32,092 deaths were recorded in the study period. Standardized mortality rates trended upward, rising from 0.24/100,000 population in 1979 to 1.10/100,000 population in 2014. The annual upward trend in mortality rates had two inflection points, in 1992 and 2008, separating three distinct time segments with an annual growth of 2.2%, 6.8%, and 2.4%, respectively. The comparison of RRs for the age groups, using the 50- to 54-year age group as a reference, and for the study period, using 1979-1984 as a reference, were 16.14 (14.44-16.36) and 6.71 (6.34-7.12), respectively. Men compared with women had higher standardized mortality rates (per 100,000 person-years) in all age groups. Conclusion: Brazilian IPF mortality rates are lower than those of other countries, suggesting underdiagnosis or underreporting. The temporal trend is similar to those reported in the literature and is not explained solely by population aging. |
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2017 |
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2017 |
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2022-03-11T16:36:54Z |
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2022-03-11T16:36:54Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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http://hdl.handle.net/1843/39996 |
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https://doi.org/10.1590/S1806-37562017000000035 |
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1806-3756 |
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https://doi.org/10.1590/S1806-37562017000000035 http://hdl.handle.net/1843/39996 |
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Universidade Federal de Minas Gerais |
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Brasil |
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MEDICINA - FACULDADE DE MEDICINA |
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Universidade Federal de Minas Gerais |
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