Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | https://doi.org/10.1016/S0140-6736(17)30818-8 http://hdl.handle.net/1843/55521 https://orcid.org/0000-0001-5689-3870 |
Resumo: | Background National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015.Methods We mapped the most widely used list of causes amenable to personal health care developed by Nolte and McKee to 32 GBD causes. We accounted for variations in cause of death certification and misclassifications through the extensive data standardisation processes and redistribution algorithms developed for GBD. To isolate the effects of personal health-care access and quality, we risk-standardised cause-specific mortality rates for each geography-year by removing the joint effects of local environmental and behavioural risks, and adding back the global levels of risk exposure as estimated for GBD 2015. We employed principal component analysis to create a single, interpretable summary measure–the Healthcare Quality and Access (HAQ) Index–on a scale of 0 to 100. The HAQ Index showed strong convergence validity as compared with other health-system indicators, including health expenditure per capita (r=0·88), an index of 11 universal health coverage interventions (r=0·83), and human resources for health per 1000 (r=0·77). We used free disposal hull analysis with bootstrapping to produce a frontier based on the relationship between the HAQ Index and the Socio-demographic Index (SDI), a measure of overall development consisting of income per capita, average years of education, and total fertility rates. This frontier allowed us to better quantify the maximum levels of personal health-care access and quality achieved across the development spectrum, and pinpoint geographies where gaps between observed and potential levels have narrowed or widened over time.Findings Between 1990 and 2015, nearly all countries and territories saw their HAQ Index values improve; nonetheless, the difference between the highest and lowest observed HAQ Index was larger in 2015 than in 1990, ranging from 28·6 to 94·6. Of 195 geographies, 167 had statistically significant increases in HAQ Index levels since 1990, with South Korea, Turkey, Peru, China, and the Maldives recording among the largest gains by 2015. Performance on the HAQ Index and individual causes showed distinct patterns by region and level of development, yet substantial heterogeneities emerged for several causes, including cancers in highest-SDI countries; chronic kidney disease, diabetes, diarrhoeal diseases, and lower respiratory infections among middle-SDI countries; and measles and tetanus among lowest-SDI countries. While the global HAQ Index average rose from 40·7 (95% uncertainty interval, 39·0–42·8) in 1990 to 53·7 (52·2–55·4) in 2015, far less progress occurred in narrowing the gap between observed HAQ Index values and maximum levels achieved; at the global level, the difference between the observed and frontier HAQ Index only decreased from 21·2 in 1990 to 20·1 in 2015. If every country and territory had achieved the highest observed HAQ Index by their corresponding level of SDI, the global average would have been 73·8 in 2015. Several countries, particularly in eastern and western sub-Saharan Africa, reached HAQ Index values similar to or beyond their development levels, whereas others, namely in southern sub-Saharan Africa, the Middle East, and south Asia, lagged behind what geographies of similar development attained between 1990 and 2015. Interpretation This novel extension of the GBD Study shows the untapped potential for personal health-care access and quality improvement across the development spectrum. Amid substantive advances in personal health care at the national level, heterogeneous patterns for individual causes in given countries or territories suggest that few places have consistently achieved optimal health-care access and quality across health-system functions and therapeutic areas. This is especially evident in middle-SDI countries, many of which have recently undergone or are currently experiencing epidemiological transitions. The HAQ Index, if paired with other measures of health-system haracteristics such as intervention coverage, could provide a robust avenue for tracking progress on universal health coverage and identifying local priorities for strengthening personal health-care quality and access throughout the world. |
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Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015Global Burden of DiseaseMortalityPersonal HealthCarga Global da DoençaRegistros de MortalidadeRegistros de Saúde PessoalBackground National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015.Methods We mapped the most widely used list of causes amenable to personal health care developed by Nolte and McKee to 32 GBD causes. We accounted for variations in cause of death certification and misclassifications through the extensive data standardisation processes and redistribution algorithms developed for GBD. To isolate the effects of personal health-care access and quality, we risk-standardised cause-specific mortality rates for each geography-year by removing the joint effects of local environmental and behavioural risks, and adding back the global levels of risk exposure as estimated for GBD 2015. We employed principal component analysis to create a single, interpretable summary measure–the Healthcare Quality and Access (HAQ) Index–on a scale of 0 to 100. The HAQ Index showed strong convergence validity as compared with other health-system indicators, including health expenditure per capita (r=0·88), an index of 11 universal health coverage interventions (r=0·83), and human resources for health per 1000 (r=0·77). We used free disposal hull analysis with bootstrapping to produce a frontier based on the relationship between the HAQ Index and the Socio-demographic Index (SDI), a measure of overall development consisting of income per capita, average years of education, and total fertility rates. This frontier allowed us to better quantify the maximum levels of personal health-care access and quality achieved across the development spectrum, and pinpoint geographies where gaps between observed and potential levels have narrowed or widened over time.Findings Between 1990 and 2015, nearly all countries and territories saw their HAQ Index values improve; nonetheless, the difference between the highest and lowest observed HAQ Index was larger in 2015 than in 1990, ranging from 28·6 to 94·6. Of 195 geographies, 167 had statistically significant increases in HAQ Index levels since 1990, with South Korea, Turkey, Peru, China, and the Maldives recording among the largest gains by 2015. Performance on the HAQ Index and individual causes showed distinct patterns by region and level of development, yet substantial heterogeneities emerged for several causes, including cancers in highest-SDI countries; chronic kidney disease, diabetes, diarrhoeal diseases, and lower respiratory infections among middle-SDI countries; and measles and tetanus among lowest-SDI countries. While the global HAQ Index average rose from 40·7 (95% uncertainty interval, 39·0–42·8) in 1990 to 53·7 (52·2–55·4) in 2015, far less progress occurred in narrowing the gap between observed HAQ Index values and maximum levels achieved; at the global level, the difference between the observed and frontier HAQ Index only decreased from 21·2 in 1990 to 20·1 in 2015. If every country and territory had achieved the highest observed HAQ Index by their corresponding level of SDI, the global average would have been 73·8 in 2015. Several countries, particularly in eastern and western sub-Saharan Africa, reached HAQ Index values similar to or beyond their development levels, whereas others, namely in southern sub-Saharan Africa, the Middle East, and south Asia, lagged behind what geographies of similar development attained between 1990 and 2015. Interpretation This novel extension of the GBD Study shows the untapped potential for personal health-care access and quality improvement across the development spectrum. Amid substantive advances in personal health care at the national level, heterogeneous patterns for individual causes in given countries or territories suggest that few places have consistently achieved optimal health-care access and quality across health-system functions and therapeutic areas. This is especially evident in middle-SDI countries, many of which have recently undergone or are currently experiencing epidemiological transitions. The HAQ Index, if paired with other measures of health-system haracteristics such as intervention coverage, could provide a robust avenue for tracking progress on universal health coverage and identifying local priorities for strengthening personal health-care quality and access throughout the world.Universidade Federal de Minas GeraisBrasilENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICAMED - DEPARTAMENTO DE CLÍNICA MÉDICAMED - DEPARTAMENTO DE PEDIATRIAUFMG2023-06-28T23:14:55Z2023-06-28T23:14:55Z2017-07-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlepdfapplication/pdfhttps://doi.org/10.1016/S0140-6736(17)30818-801406736http://hdl.handle.net/1843/55521https://orcid.org/0000-0001-5689-3870engThe LancetChandrashekhar t SreeramareddyVasiliki StathopoulouNicholas SteelCaitlyn SteinerSabine SteinkeEllen NolteCarl Abelardo t AntonioMark Andrew StokesSaverio StrangesMark StrongKonstantinos StroumpoulisAdrienne ChewMirriam ChibalabalaChioma Ezinne 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dc.title.none.fl_str_mv |
Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015 |
title |
Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015 |
spellingShingle |
Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015 Chandrashekhar t Sreeramareddy Global Burden of Disease Mortality Personal Health Carga Global da Doença Registros de Mortalidade Registros de Saúde Pessoal |
title_short |
Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015 |
title_full |
Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015 |
title_fullStr |
Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015 |
title_full_unstemmed |
Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015 |
title_sort |
Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015 |
author |
Chandrashekhar t Sreeramareddy |
author_facet |
Chandrashekhar t Sreeramareddy Vasiliki Stathopoulou Nicholas Steel Caitlyn Steiner Sabine Steinke Ellen Nolte Carl Abelardo t Antonio Mark Andrew Stokes Saverio Stranges Mark Strong Konstantinos Stroumpoulis Adrienne Chew Mirriam Chibalabala Chioma Ezinne Chibueze Vesper Hichilombwe Chisumpa Abdulaal a Chitheer Rajiv Chowdhury Hanne Christensen Devasahayam Jesudas Christopher Liliana g Ciobanu Rafael Tabarés-seisdedos Seok-jun Yoon Massimo Cirillo Semaw Ferede Abera Megan s Coggeshall Leslie Trumbull Cooper Monica Cortinovis John a Crump Koustuv Dalal Hadi Danawi Lalit Dandona Rakhi Dandona Mustafa z Younis Karen m Tabb Paul i Dargan Jose Das Neves Biju Abraham Gail Davey Dragos v Davitoiu Kairat Davletov Diego de Leo Liana c Del Gobbo Borja Del Pozo-cruz Chuanhua yu Robert p Dellavalle Getachew Redae Taffere Kebede Deribe Amare Deribew Don c Des Jarlais Girmatsion Fisseha Abreha Subhojit Dey Samath d Dharmaratne Daniel Dicker Eric l Ding Zoubida Zaidi Klara Dokova e Ray Dorsey Roberto Tchio Talongwa Kerrie e Doyle Manisha Dubey Rebecca Ehrenkranz Christian Lycke Ellingsen Kelemework Adane Iqbal Elyazar Ahmadali Enayati Maysaa el Sayed Zaki Sergey Petrovich Ermakov Babak Eshrati Alireza Esteghamati Musharaf Tarajia Kara Estep Thomas Fürst Imad d a Faghmous Fanuel Belayneh Bekele Fanuel Emerito Jose Aquino Faraon Ademola Lukman Adelekan Sachin r Atre Talha a Farid Carla Sofia e sa Farinha Andre Faro Maryam s Farvid Mohammad Tavakkoli Farshad Farzadfar Valery l Feigin Andrea b Feigl Seyed-mohammad Fereshtehnejad Jefferson g Fernandes Carlos Zambrana-torrelio João c Fernandes Ifedayo Morayo o Adetifa Tesfaye Regassa Feyissa Florian Fischer Christina Fitzmaurice Nuno Taveira Thomas d Fleming Nataliya Foigt Kyle j Foreman Mohammad h Forouzanfar Tomas Zapata Richard c Franklin Joseph Frostad Tsegaye Tewelde G/hiwot Nancy Fullman Ashkan Afshin Emmanuela Gakidou Stephanie Teeple Ketevan Gambashidze Amiran Gamkrelidze Wayne Gao Zerihun Menlkalew Zenebe Alberto l Garcia-basteiro Teshome Gebre Amanuel Tesfay Gebremedhin Mengistu Welday Gebremichael Alemseged Aregay Gebru Amha Admasie Gelaye Arnav Agarwal Teketo Kassaw Tegegne Johanna m Geleijnse Ricard Genova-maleras Sanjay Zodpey Katherine b Gibney Ababi Zergaw Giref Melkamu Dedefo Gishu Giorgia Giussani William w Godwin Audra Gold Ellen m Goldberg Philimon n Gona al Artaman Sanjay Kumar Agarwal Lela Sturua Amador Goodridge Sameer Vali Gopalani Atsushi Goto Nicholas Graetz Felix Greaves Max Griswold Peter Imre Guban Harish Chander Gugnani Prakash c Gupta Arash Tehrani-banihashemi Leo Zoeckler Rahul Gupta Sunilkumar Agarwal Rajeev Gupta Tanush Gupta Vipin Gupta Tesfa Dejenie Habtewold Nima Hafezi-nejad Demewoz Haile Alemayehu Desalegne Hailu Gessessew Bugssa Hailu Liesl Joanna Zuhlke Tesfalidet Tekelab Alex Hakuzimana Randah Ribhi Hamadeh Anurag Agrawal Mitiku Teshome Hambisa Samer Hamidi Mouhanad Hammami Graeme j Hankey Yuantao Hao Hilda l Harb Christopher j l Murray Habtamu Abera Hareri Dejen Yemane Tekle Josep Maria Haro Mohammad Sadegh Hassanvand Rasmus Havmoeller Aliasghar Ahmad Kiadaliri Roderick j Hay Simon i Hay Delia Hendrie Ileana Beatriz Heredia-pi Amanuel Alemu Abajobir Hans w Hoek Masako Horino Girma Temam Shifa Nobuyuki Horita h Dean Hosgood Aung Soe Htet Guoqing hu Alireza Ahmadi Hsiang Huang John j Huang Leticia Avila-burgos Bethany m Huntley Chantal Huynh Kim Moesgaard Iburg Abdullah Sulieman Terkawi Bogdan Vasile Ileanu Kaire Innos Asnake Ararsa Irenso Nader Jahanmehr Mihajlo b Jakovljevic Kedir Yimam Ahmed Euripide Frinel g Arthur Avokpaho Peter James Spencer Lewis James Mehdi Javanbakht Sudha p Jayaraman Azeb Gebresilassie Tesema Achala Upendra Jayatilleke Panniyammakal Jeemon Vivekanand Jha Denny John Catherine Johnson Beatriz Paulina Ayala Quintanilla Sarah c Johnson Muktar Beshir Ahmed Jost b Jonas Knud Juel Zubair Kabir js Thakur Yogeshwar Kalkonde Ritul Kamal Haidong Kan Andre Karch Ashish Awasthi Corine Kakizi Karema Seyed m Karimi Amir Kasaeian Rufus Olusola Akinyemi Nicholas j Kassebaum Anshul Kastor Alan j Thomson Srinivasa Vittal Katikireddi Konstantin Kazanjan Peter Njenga Keiyoro Nebiyu Negussu Ayele Laura Kemmer Andrew Haddon Kemp Andre Pascal Kengne Amene Abebe Kerbo Maia Kereselidze Reed j d Sorensen Tomi f Akinyemiju Taavi Tillmann Chandrasekharan Nair Kesavachandran Yousef Saleh Khader Peter Azzopardi Ibrahim Khalil Abdur Rahman Khan Ejaz Ahmad Khan Gulfaraz Khan Young-ho Khang Abdullah Tawfih Abdullah Khoja Irma Khonelidze Jagdish Khubchandani Tenaw Yimer Tiruye Nadia Akseer Muawiyyah Babale Sufiyan Getiye Dejenu Kibret Daniel Kim Pauline Kim Yun Jin Kim Ruth w Kimokoti Yohannes Kinfu Niranjan Kissoon Miia Kivipelto Yoshihiro Kokubo Hamid Asayesh Huda Omer ba Saleem Anneli Kolk Ziyad Al-aly Dhaval Kolte Jacek a Kopec Soewarta Kosen Parvaiz a Koul ai Koyanagi Michael Kravchenko Sanjay Krishnaswami Kristopher j Krohn Till Bärnighausen Ruoyan Tobe-gai Barthelemy Kuate Defo Burcu Kucuk Bicer Khurshid Alam Ernst j Kuipers Veena s Kulkarni g Anil Kumar Fekede Asefa Kumsa Michael Kutz Hmwe h Kyu Umar Bacha Anton Carl Jonas Lager Marcello Tonelli Aparna Lal Dharmesh Kumar Lal Ratilal Lalloo Noore Alam Tea Lallukka Qing Lan Sinead m Langan Van c Lansingh Alaa Badawi Heidi j Larson Anders Larsson Roman Topor-madry Dennis Odai Laryea Asma Abdul Latif Alicia Elena Beatriz Lawrynowicz Janet l Leasher Sayed Saidul Alam James Leigh Mall Leinsalu Kalkidan Hassen Abate Cheru Tesema Leshargie Janni Leung Ricky Leung Miguel Tortajada Miriam Levi Xiaofeng Liang Stephen s Lim Margaret Lind Shai Linn Zewdie Aderaw Alemu Amitava Banerjee Steven e Lipshultz Patrick Liu Yang Liu Loon-tzian lo Christopher Troeger Giancarlo Logroscino Alan d Lopez Scott a Lorch Paulo a Lotufo Rafael Lozano Aleksandra Barac Raimundas Lunevicius Kefyalew Addis Alene Ronan a Lyons Erlyn Rachelle King Macarayan Mark t Mackay Thomas Truelsen Hassan Magdy Abd el Razek Mohammed Magdy Abd el Razek Mahdi Mahdavi Azeem Majeed Miguel a Barboza Reza Malekzadeh Deborah Carvalho Malta Lorenzo g Mantovani Lily Alexander Tsegahun Manyazewal Chabila c Mapoma Abera Kenay Tura Wagner Marcenes Guy b Marks Neal Marquez Suzanne l Barker-collo Jose Martinez-raga Melvin Barrientos Marzan João Massano Manu Raj Mathur Pallab k Maulik Raghib Ali Mohsen Mazidi Uche s Uchendu Colm Mcalinden John j Mcgrath Lope h Barrero Claire Mcnellan Peter a Meaney Alem Mehari Man Mohan Mehndiratta Toni Meier Alemayehu b Mekonnen Kidanu Gebremariam Meles Thomas Bollyky Kingsley n Ukwaja Syed Danish Ali Rizwan Abdulkader Suliankatchi Ziad a Memish Melkamu Merid Mengesha Desalegn Tadese Mengiste Mubarek Abera Mengistie Bereket Gebremichael Menota George a Mensah Seid Tiku Mereta Atte Meretoja Tuomo j Meretoja Eduardo a Undurraga Sanjay Basu Haftay Berhane Mezgebe Reza Alizadeh-navaei Renata Micha Anoushka Millear Edward j Mills Shawn Minnig Mojde Mirarefin Erkin m Mirrakhimov Charles n Mock Karzan Abdulmuhsin Mohammad Bernhard t Baune Reza Assadi Shafiu Mohammed Sanjay k Mohanty Ala'a Alkerwi Ali h Mokdad Glen Liddell d Mola Mariam Molokhia Lorenzo Monasta Marcella Montico Maziar Moradi-lakeh Kaleab Baye Paula Moraga Chigozie Jesse Uneke Lidia Morawska Rintaro Mori Mark Moses François Alla Ulrich o Mueller Srinivas Murthy Kamarul Imran Musa Jean b Nachega Yibeltal Tebekaw Bayou Chie Nagata Gabriele Nagel Olalekan a Uthman Mohsen Naghavi Aliya Naheed Luigi Naldi Vinay Nangia Peter Allebeck Bruno Ramos Nascimento Ionut Negoi Shahrzad Bazargan-hejazi Sudan Prasad Neupane Charles r Newton Marie ng Job f m Van Boven Frida Namnyak Ngalesoni Josephine Wanjiku Ngunjiri Grant Nguyen Dina Nur Anggraini Ningrum Sandra Nolte Christine Allen Cristiana Abbafati Marika Nomura Ole f Norheim bo Norrving Jean Jacques n Noubiap Rita Van Dingenen Carla Makhlouf Obermeyer Felix Akpojene Ogbo In-hwan oh Anselm Okoro Olanrewaju Oladimeji Neeraj Bedi Andrew Toyin Olagunju Rajaa Al-raddadi Pedro r Olivares Helen e Olsen Bolajoko Olubukunola Olusanya Santosh Varughese Jacob Olusegun Olusanya John Nelson Opio Eyal Oren Alberto Ortiz Ettore Beghi Richard h Osborne Majdi Osman Mayowa o Owolabi Ubai Alsharif Mahesh pa Amanda w Pain Tommi Vasankari Smita Pakhale Elizabeth Palomares Castillo Adrian Pana Yannick Béjot Christina Papachristou Mahboubeh Parsaeian Tejas Patel George c Patton Deepak Paudel Khalid a Altirkawi Vinod k Paul Narayanaswamy Venketasubramanian Neil Pearce David m Pereira Aminu k Bello Rogelio Perez-padilla Fernando Perez-ruiz Norberto Perico Konrad Pesudovs Max Petzold Michael Robert Phillips David m Pigott Elena Alvarez Martin Francesco s Violante Julian David Pillay Jiandong Sun Christine Pinho Suzanne Polinder Constance d Pond v Prakash Manorama Purwar Mostafa Qorbani d Alex Quistberg Amir Radfar Anwar Rafay Sergey k Vladimirov Derrick a Bennett Martin Mckee Nelson Alvis-guzman Kazem Rahimi Vafa Rahimi-movaghar Mahfuzar Rahman Mohammad Hifz ur Rahman Rajesh Kumar Rai Usha Ram Saleem m Rana Zane Rankin Isabela m Bensenor Vasiliy Victorovich Vlassov Paturi Vishnupriya Rao Puja c Rao Azmeraw t Amare Salman Rawaf Maria Albertina Santiago Rego Marissa Reitsma Giuseppe Remuzzi Andre m n n Renzaho Serge Resnikoff Adugnaw Berhane Satar Rezaei Ayalew Astatkie Mohammad Sadegh Rezai Antonio Luiz Pinho Ribeiro Hirbo Shore Roba Erfan Amini Mohammad Bagher Rokni Luca Ronfani Gholamreza Roshandel Gregory a Roth Eduardo Bernabé Dietrich Rothenbacher Nawal k Roy Stein Emil Vollset Perminder s Sachdev Ben Benasco Sackey Mohammad Yahya Saeedi Saeid Safiri Walid Ammar Rajesh Sagar Mohammad Ali Sahraian Oscar Alberto Bernal Muhammad Muhammad Saleh Joshua a Salomon Abdallah m Samy Theo Vos Juan Ramon Sanabria Maria Dolores Sanchez-niño Logan Sandar Itamar s Santos João Vasco Santos Joshu Amo-adjei Addisu Shunu Beyene Milena m Santric Milicevic Rodrigo Sarmiento-suarez Benn Sartorius Maheswar Satpathy Joseph a Wagner Miloje Savic Monika Sawhney Mete i Saylan Ben Schöttker Aletta e Schutte Ryan Mbarber David c Schwebel Yaw Ampem Amoako Soraya Seedat Abdulbasit Musa Seid Canaan Negash Seifu Tolassa Wakayo Sadaf g Sepanlou Berrin Serdar Edson e Servan-mori Tesfaye Setegn Kaja m Abbas Katya Anne Shackelford Amira Shaheen Saeid Shahraz Benjamin o Anderson Masood Ali Shaikh Marina Shakh-nazarova Stephen g Waller Mansour Shamsipour Sheikh Mohammed Shariful Islam Jayendra Sharma Tariku Jibat Beyene Rajesh Sharma Jun She Sara Sheikhbahaei Jiabin Shen Peilin Shi Sofia Androudi Mika Shigematsu Judd l Walson Min-jeong Shin Rahman Shiri Zulfiqar a Bhutta Haitham Shoman Mark g Shrime Ephrem Lejore Sibamo Sibamo Inga Dora Sigfusdottir Diego Augusto Santos Silva Dayane Gabriele Alves Silveira Shireen Sindi Hossein Ansari Haidong Wang Abhishek Singh Patrick Sur Jasvinder a Singh om Prakash Singh Prashant Kumar Singh Virendra Singh Abiy Hiruye Sinke Aklilu Endalamaw Sinshaw Vegard Skirbekk Karen Sliwa Alison Smith Yuan-pang Wang Sibhatu Biadgilign Mustafa Geleto Ansha Eugene Sobngwi Samir Soneji Joan b Soriano Tatiane Cristina Moraes Sousa Luciano a Sposato David a Watkins Elisabete Weiderpass Tesfay Mehari Atey Robert g Weintraub Boris Bikbov Chi-pang Wen Andrea Werdecker Joshua Wesana Ronny Westerman Harvey a Whiteford James d Wilkinson Charles Shey Wiysonge Belete Getahun Woldeyes Charles d a Wolfe Suleman Atique Sait Mentes Birlik Sungho Won Abdulhalik Workicho Shimelash Bitew Workie Mamo Wubshet Denis Xavier Gelin xu Ajit Kumar Yadav Mohsen Yaghoubi Bereket Yakob Lijing l Yan Charles Birungi Niguse Tadele Atnafu Yuichiro Yano Mehdi Yaseri Hassen Hamid Yimam Paul Yip Naohiro Yonemoto Stan Biryukov Donal Bisanzio Habtamu Mellie Bizuayehu Dipan Bose Foad Abd-allah Michael Brainin Soumya Swaminathan Michael Brauer Alexandra Brazinova Nicholas j k Breitborde Hermann Brenner Zahid a Butt Rosario Cárdenas Lucero Cahuana-hurtado Ismael Ricardo Campos-nonato Josip Car Abdishakur m Abdulle Johan Ärnlöv Juan Jesus Carrero Daniel Casey Valeria Caso Carlos a Castañeda-orjuela Jacqueline Castillo Rivas Ferrán Catalá-lópez Pedro Cecilio Kelly Cercy Fiona j Charlson Alan z Chen Bryan l Sykes Ahmed Abdulahi Abdurahman |
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Vasiliki Stathopoulou Nicholas Steel Caitlyn Steiner Sabine Steinke Ellen Nolte Carl Abelardo t Antonio Mark Andrew Stokes Saverio Stranges Mark Strong Konstantinos Stroumpoulis Adrienne Chew Mirriam Chibalabala Chioma Ezinne Chibueze Vesper Hichilombwe Chisumpa Abdulaal a Chitheer Rajiv Chowdhury Hanne Christensen Devasahayam Jesudas Christopher Liliana g Ciobanu Rafael Tabarés-seisdedos Seok-jun Yoon Massimo Cirillo Semaw Ferede Abera Megan s Coggeshall Leslie Trumbull Cooper Monica Cortinovis John a Crump Koustuv Dalal Hadi Danawi Lalit Dandona Rakhi Dandona Mustafa z Younis Karen m Tabb Paul i Dargan Jose Das Neves Biju Abraham Gail Davey Dragos v Davitoiu Kairat Davletov Diego de Leo Liana c Del Gobbo Borja Del Pozo-cruz Chuanhua yu Robert p Dellavalle Getachew Redae Taffere Kebede Deribe Amare Deribew Don c Des Jarlais Girmatsion Fisseha Abreha Subhojit Dey Samath d Dharmaratne Daniel Dicker Eric l Ding Zoubida Zaidi Klara Dokova e Ray Dorsey Roberto Tchio Talongwa Kerrie e Doyle Manisha Dubey Rebecca Ehrenkranz Christian Lycke Ellingsen Kelemework Adane Iqbal Elyazar Ahmadali Enayati Maysaa el Sayed Zaki Sergey Petrovich Ermakov Babak Eshrati Alireza Esteghamati Musharaf Tarajia Kara Estep Thomas Fürst Imad d a Faghmous Fanuel Belayneh Bekele Fanuel Emerito Jose Aquino Faraon Ademola Lukman Adelekan Sachin r Atre Talha a Farid Carla Sofia e sa Farinha Andre Faro Maryam s Farvid Mohammad Tavakkoli Farshad Farzadfar Valery l Feigin Andrea b Feigl Seyed-mohammad Fereshtehnejad Jefferson g Fernandes Carlos Zambrana-torrelio João c Fernandes Ifedayo Morayo o Adetifa Tesfaye Regassa Feyissa Florian Fischer Christina Fitzmaurice Nuno Taveira Thomas d Fleming Nataliya Foigt Kyle j Foreman Mohammad h Forouzanfar Tomas Zapata Richard c Franklin Joseph Frostad Tsegaye Tewelde G/hiwot Nancy Fullman Ashkan Afshin Emmanuela Gakidou Stephanie Teeple Ketevan Gambashidze Amiran Gamkrelidze Wayne Gao Zerihun Menlkalew Zenebe Alberto l Garcia-basteiro Teshome Gebre Amanuel Tesfay Gebremedhin Mengistu Welday Gebremichael Alemseged Aregay Gebru Amha Admasie Gelaye Arnav Agarwal Teketo Kassaw Tegegne Johanna m Geleijnse Ricard Genova-maleras Sanjay Zodpey Katherine b Gibney Ababi Zergaw Giref Melkamu Dedefo Gishu Giorgia Giussani William w Godwin Audra Gold Ellen m Goldberg Philimon n Gona al Artaman Sanjay Kumar Agarwal Lela Sturua Amador Goodridge Sameer Vali Gopalani Atsushi Goto Nicholas Graetz Felix Greaves Max Griswold Peter Imre Guban Harish Chander Gugnani Prakash c Gupta Arash Tehrani-banihashemi Leo Zoeckler Rahul Gupta Sunilkumar Agarwal Rajeev Gupta Tanush Gupta Vipin Gupta Tesfa Dejenie Habtewold Nima Hafezi-nejad Demewoz Haile Alemayehu Desalegne Hailu Gessessew Bugssa Hailu Liesl Joanna Zuhlke Tesfalidet Tekelab Alex Hakuzimana Randah Ribhi Hamadeh Anurag Agrawal Mitiku Teshome Hambisa Samer Hamidi Mouhanad Hammami Graeme j Hankey Yuantao Hao Hilda l Harb Christopher j l Murray Habtamu Abera Hareri Dejen Yemane Tekle Josep Maria Haro Mohammad Sadegh Hassanvand Rasmus Havmoeller Aliasghar Ahmad Kiadaliri Roderick j Hay Simon i Hay Delia Hendrie Ileana Beatriz Heredia-pi Amanuel Alemu Abajobir Hans w Hoek Masako Horino Girma Temam Shifa Nobuyuki Horita h Dean Hosgood Aung Soe Htet Guoqing hu Alireza Ahmadi Hsiang Huang John j Huang Leticia Avila-burgos Bethany m Huntley Chantal Huynh Kim Moesgaard Iburg Abdullah Sulieman Terkawi Bogdan Vasile Ileanu Kaire Innos Asnake Ararsa Irenso Nader Jahanmehr Mihajlo b Jakovljevic Kedir Yimam Ahmed Euripide Frinel g Arthur Avokpaho Peter James Spencer Lewis James Mehdi Javanbakht Sudha p Jayaraman Azeb Gebresilassie Tesema Achala Upendra Jayatilleke Panniyammakal Jeemon Vivekanand Jha Denny John Catherine Johnson Beatriz Paulina Ayala Quintanilla Sarah c Johnson Muktar Beshir Ahmed Jost b Jonas Knud Juel Zubair Kabir js Thakur Yogeshwar Kalkonde Ritul Kamal Haidong Kan Andre Karch Ashish Awasthi Corine Kakizi Karema Seyed m Karimi Amir Kasaeian Rufus Olusola Akinyemi Nicholas j Kassebaum Anshul Kastor Alan j Thomson Srinivasa Vittal Katikireddi Konstantin Kazanjan Peter Njenga Keiyoro Nebiyu Negussu Ayele Laura Kemmer Andrew Haddon Kemp Andre Pascal Kengne Amene Abebe Kerbo Maia Kereselidze Reed j d Sorensen Tomi f Akinyemiju Taavi Tillmann Chandrasekharan Nair Kesavachandran Yousef Saleh Khader Peter Azzopardi Ibrahim Khalil Abdur Rahman Khan Ejaz Ahmad Khan Gulfaraz Khan Young-ho Khang Abdullah Tawfih Abdullah Khoja Irma Khonelidze Jagdish Khubchandani Tenaw Yimer Tiruye Nadia Akseer Muawiyyah Babale Sufiyan Getiye Dejenu Kibret Daniel Kim Pauline Kim Yun Jin Kim Ruth w Kimokoti Yohannes Kinfu Niranjan Kissoon Miia Kivipelto Yoshihiro Kokubo Hamid Asayesh Huda Omer ba Saleem Anneli Kolk Ziyad Al-aly Dhaval Kolte Jacek a Kopec Soewarta Kosen Parvaiz a Koul ai Koyanagi Michael Kravchenko Sanjay Krishnaswami Kristopher j Krohn Till Bärnighausen Ruoyan Tobe-gai Barthelemy Kuate Defo Burcu Kucuk Bicer Khurshid Alam Ernst j Kuipers Veena s Kulkarni g Anil Kumar Fekede Asefa Kumsa Michael Kutz Hmwe h Kyu Umar Bacha Anton Carl Jonas Lager Marcello Tonelli Aparna Lal Dharmesh Kumar Lal Ratilal Lalloo Noore Alam Tea Lallukka Qing Lan Sinead m Langan Van c Lansingh Alaa Badawi Heidi j Larson Anders Larsson Roman Topor-madry Dennis Odai Laryea Asma Abdul Latif Alicia Elena Beatriz Lawrynowicz Janet l Leasher Sayed Saidul Alam James Leigh Mall Leinsalu Kalkidan Hassen Abate Cheru Tesema Leshargie Janni Leung Ricky Leung Miguel Tortajada Miriam Levi Xiaofeng Liang Stephen s Lim Margaret Lind Shai Linn Zewdie Aderaw Alemu Amitava Banerjee Steven e Lipshultz Patrick Liu Yang Liu Loon-tzian lo Christopher Troeger Giancarlo Logroscino Alan d Lopez Scott a Lorch Paulo a Lotufo Rafael Lozano Aleksandra Barac Raimundas Lunevicius Kefyalew Addis Alene Ronan a Lyons Erlyn Rachelle King Macarayan Mark t Mackay Thomas Truelsen Hassan Magdy Abd el Razek Mohammed Magdy Abd el Razek Mahdi Mahdavi Azeem Majeed Miguel a Barboza Reza Malekzadeh Deborah Carvalho Malta Lorenzo g Mantovani Lily Alexander Tsegahun Manyazewal Chabila c Mapoma Abera Kenay Tura Wagner Marcenes Guy b Marks Neal Marquez Suzanne l Barker-collo Jose Martinez-raga Melvin Barrientos Marzan João Massano Manu Raj Mathur Pallab k Maulik Raghib Ali Mohsen Mazidi Uche s Uchendu Colm Mcalinden John j Mcgrath Lope h Barrero Claire Mcnellan Peter a Meaney Alem Mehari Man Mohan Mehndiratta Toni Meier Alemayehu b Mekonnen Kidanu Gebremariam Meles Thomas Bollyky Kingsley n Ukwaja Syed Danish Ali Rizwan Abdulkader Suliankatchi Ziad a Memish Melkamu Merid Mengesha Desalegn Tadese Mengiste Mubarek Abera Mengistie Bereket Gebremichael Menota George a Mensah Seid Tiku Mereta Atte Meretoja Tuomo j Meretoja Eduardo a Undurraga Sanjay Basu Haftay Berhane Mezgebe Reza Alizadeh-navaei Renata Micha Anoushka Millear Edward j Mills Shawn Minnig Mojde Mirarefin Erkin m Mirrakhimov Charles n Mock Karzan Abdulmuhsin Mohammad Bernhard t Baune Reza Assadi Shafiu Mohammed Sanjay k Mohanty Ala'a Alkerwi Ali h Mokdad Glen Liddell d Mola Mariam Molokhia Lorenzo Monasta Marcella Montico Maziar Moradi-lakeh Kaleab Baye Paula Moraga Chigozie Jesse Uneke Lidia Morawska Rintaro Mori Mark Moses François Alla Ulrich o Mueller Srinivas Murthy Kamarul Imran Musa Jean b Nachega Yibeltal Tebekaw Bayou Chie Nagata Gabriele Nagel Olalekan a Uthman Mohsen Naghavi Aliya Naheed Luigi Naldi Vinay Nangia Peter Allebeck Bruno Ramos Nascimento Ionut Negoi Shahrzad Bazargan-hejazi Sudan Prasad Neupane Charles r Newton Marie ng Job f m Van Boven Frida Namnyak Ngalesoni Josephine Wanjiku Ngunjiri Grant Nguyen Dina Nur Anggraini Ningrum Sandra Nolte Christine Allen Cristiana Abbafati Marika Nomura Ole f Norheim bo Norrving Jean Jacques n Noubiap Rita Van Dingenen Carla Makhlouf Obermeyer Felix Akpojene Ogbo In-hwan oh Anselm Okoro Olanrewaju Oladimeji Neeraj Bedi Andrew Toyin Olagunju Rajaa Al-raddadi Pedro r Olivares Helen e Olsen Bolajoko Olubukunola Olusanya Santosh Varughese Jacob Olusegun Olusanya John Nelson Opio Eyal Oren Alberto Ortiz Ettore Beghi Richard h Osborne Majdi Osman Mayowa o Owolabi Ubai Alsharif Mahesh pa Amanda w Pain Tommi Vasankari Smita Pakhale Elizabeth Palomares Castillo Adrian Pana Yannick Béjot Christina Papachristou Mahboubeh Parsaeian Tejas Patel George c Patton Deepak Paudel Khalid a Altirkawi Vinod k Paul Narayanaswamy Venketasubramanian Neil Pearce David m Pereira Aminu k Bello Rogelio Perez-padilla Fernando Perez-ruiz Norberto Perico Konrad Pesudovs Max Petzold Michael Robert Phillips David m Pigott Elena Alvarez Martin Francesco s Violante Julian David Pillay Jiandong Sun Christine Pinho Suzanne Polinder Constance d Pond v Prakash Manorama Purwar Mostafa Qorbani d Alex Quistberg Amir Radfar Anwar Rafay Sergey k Vladimirov Derrick a Bennett Martin Mckee Nelson Alvis-guzman Kazem Rahimi Vafa Rahimi-movaghar Mahfuzar Rahman Mohammad Hifz ur Rahman Rajesh Kumar Rai Usha Ram Saleem m Rana Zane Rankin Isabela m Bensenor Vasiliy Victorovich Vlassov Paturi Vishnupriya Rao Puja c Rao Azmeraw t Amare Salman Rawaf Maria Albertina Santiago Rego Marissa Reitsma Giuseppe Remuzzi Andre m n n Renzaho Serge Resnikoff Adugnaw Berhane Satar Rezaei Ayalew Astatkie Mohammad Sadegh Rezai Antonio Luiz Pinho Ribeiro Hirbo Shore Roba Erfan Amini Mohammad Bagher Rokni Luca Ronfani Gholamreza Roshandel Gregory a Roth Eduardo Bernabé Dietrich Rothenbacher Nawal k Roy Stein Emil Vollset Perminder s Sachdev Ben Benasco Sackey Mohammad Yahya Saeedi Saeid Safiri Walid Ammar Rajesh Sagar Mohammad Ali Sahraian Oscar Alberto Bernal Muhammad Muhammad Saleh Joshua a Salomon Abdallah m Samy Theo Vos Juan Ramon Sanabria Maria Dolores Sanchez-niño Logan Sandar Itamar s Santos João Vasco Santos Joshu Amo-adjei Addisu Shunu Beyene Milena m Santric Milicevic Rodrigo Sarmiento-suarez Benn Sartorius Maheswar Satpathy Joseph a Wagner Miloje Savic Monika Sawhney Mete i Saylan Ben Schöttker Aletta e Schutte Ryan Mbarber David c Schwebel Yaw Ampem Amoako Soraya Seedat Abdulbasit Musa Seid Canaan Negash Seifu Tolassa Wakayo Sadaf g Sepanlou Berrin Serdar Edson e Servan-mori Tesfaye Setegn Kaja m Abbas Katya Anne Shackelford Amira Shaheen Saeid Shahraz Benjamin o Anderson Masood Ali Shaikh Marina Shakh-nazarova Stephen g Waller Mansour Shamsipour Sheikh Mohammed Shariful Islam Jayendra Sharma Tariku Jibat Beyene Rajesh Sharma Jun She Sara Sheikhbahaei Jiabin Shen Peilin Shi Sofia Androudi Mika Shigematsu Judd l Walson Min-jeong Shin Rahman Shiri Zulfiqar a Bhutta Haitham Shoman Mark g Shrime Ephrem Lejore Sibamo Sibamo Inga Dora Sigfusdottir Diego Augusto Santos Silva Dayane Gabriele Alves Silveira Shireen Sindi Hossein Ansari Haidong Wang Abhishek Singh Patrick Sur Jasvinder a Singh om Prakash Singh Prashant Kumar Singh Virendra Singh Abiy Hiruye Sinke Aklilu Endalamaw Sinshaw Vegard Skirbekk Karen Sliwa Alison Smith Yuan-pang Wang Sibhatu Biadgilign Mustafa Geleto Ansha Eugene Sobngwi Samir Soneji Joan b Soriano Tatiane Cristina Moraes Sousa Luciano a Sposato David a Watkins Elisabete Weiderpass Tesfay Mehari Atey Robert g Weintraub Boris Bikbov Chi-pang Wen Andrea Werdecker Joshua Wesana Ronny Westerman Harvey a Whiteford James d Wilkinson Charles Shey Wiysonge Belete Getahun Woldeyes Charles d a Wolfe Suleman Atique Sait Mentes Birlik Sungho Won Abdulhalik Workicho Shimelash Bitew Workie Mamo Wubshet Denis Xavier Gelin xu Ajit Kumar Yadav Mohsen Yaghoubi Bereket Yakob Lijing l Yan Charles Birungi Niguse Tadele Atnafu Yuichiro Yano Mehdi Yaseri Hassen Hamid Yimam Paul Yip Naohiro Yonemoto Stan Biryukov Donal Bisanzio Habtamu Mellie Bizuayehu Dipan Bose Foad Abd-allah Michael Brainin Soumya Swaminathan Michael Brauer Alexandra Brazinova Nicholas j k Breitborde Hermann Brenner Zahid a Butt Rosario Cárdenas Lucero Cahuana-hurtado Ismael Ricardo Campos-nonato Josip Car Abdishakur m Abdulle Johan Ärnlöv Juan Jesus Carrero Daniel Casey Valeria Caso Carlos a Castañeda-orjuela Jacqueline Castillo Rivas Ferrán Catalá-lópez Pedro Cecilio Kelly Cercy Fiona j Charlson Alan z Chen Bryan l Sykes Ahmed Abdulahi Abdurahman |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Chandrashekhar t Sreeramareddy Vasiliki Stathopoulou Nicholas Steel Caitlyn Steiner Sabine Steinke Ellen Nolte Carl Abelardo t Antonio Mark Andrew Stokes Saverio Stranges Mark Strong Konstantinos Stroumpoulis Adrienne Chew Mirriam Chibalabala Chioma Ezinne Chibueze Vesper Hichilombwe Chisumpa Abdulaal a Chitheer Rajiv Chowdhury Hanne Christensen Devasahayam Jesudas Christopher Liliana g Ciobanu Rafael Tabarés-seisdedos Seok-jun Yoon Massimo Cirillo Semaw Ferede Abera Megan s Coggeshall Leslie Trumbull Cooper Monica Cortinovis John a Crump Koustuv Dalal Hadi Danawi Lalit Dandona Rakhi Dandona Mustafa z Younis Karen m Tabb Paul i Dargan Jose Das Neves Biju Abraham Gail Davey Dragos v Davitoiu Kairat Davletov Diego de Leo Liana c Del Gobbo Borja Del Pozo-cruz Chuanhua yu Robert p Dellavalle Getachew Redae Taffere Kebede Deribe Amare Deribew Don c Des Jarlais Girmatsion Fisseha Abreha Subhojit Dey Samath d Dharmaratne Daniel Dicker Eric l Ding Zoubida Zaidi Klara Dokova e Ray Dorsey Roberto Tchio Talongwa Kerrie e Doyle Manisha Dubey Rebecca Ehrenkranz Christian Lycke Ellingsen Kelemework Adane Iqbal Elyazar Ahmadali Enayati Maysaa el Sayed Zaki Sergey Petrovich Ermakov Babak Eshrati Alireza Esteghamati Musharaf Tarajia Kara Estep Thomas Fürst Imad d a Faghmous Fanuel Belayneh Bekele Fanuel Emerito Jose Aquino Faraon Ademola Lukman Adelekan Sachin r Atre Talha a Farid Carla Sofia e sa Farinha Andre Faro Maryam s Farvid Mohammad Tavakkoli Farshad Farzadfar Valery l Feigin Andrea b Feigl Seyed-mohammad Fereshtehnejad Jefferson g Fernandes Carlos Zambrana-torrelio João c Fernandes Ifedayo Morayo o Adetifa Tesfaye Regassa Feyissa Florian Fischer Christina Fitzmaurice Nuno Taveira Thomas d Fleming Nataliya Foigt Kyle j Foreman Mohammad h Forouzanfar Tomas Zapata Richard c Franklin Joseph Frostad Tsegaye Tewelde G/hiwot Nancy Fullman Ashkan Afshin Emmanuela Gakidou Stephanie Teeple Ketevan Gambashidze Amiran Gamkrelidze Wayne Gao Zerihun Menlkalew Zenebe Alberto l Garcia-basteiro Teshome Gebre Amanuel Tesfay Gebremedhin Mengistu Welday Gebremichael Alemseged Aregay Gebru Amha Admasie Gelaye Arnav Agarwal Teketo Kassaw Tegegne Johanna m Geleijnse Ricard Genova-maleras Sanjay Zodpey Katherine b Gibney Ababi Zergaw Giref Melkamu Dedefo Gishu Giorgia Giussani William w Godwin Audra Gold Ellen m Goldberg Philimon n Gona al Artaman Sanjay Kumar Agarwal Lela Sturua Amador Goodridge Sameer Vali Gopalani Atsushi Goto Nicholas Graetz Felix Greaves Max Griswold Peter Imre Guban Harish Chander Gugnani Prakash c Gupta Arash Tehrani-banihashemi Leo Zoeckler Rahul Gupta Sunilkumar Agarwal Rajeev Gupta Tanush Gupta Vipin Gupta Tesfa Dejenie Habtewold Nima Hafezi-nejad Demewoz Haile Alemayehu Desalegne Hailu Gessessew Bugssa Hailu Liesl Joanna Zuhlke Tesfalidet Tekelab Alex Hakuzimana Randah Ribhi Hamadeh Anurag Agrawal Mitiku Teshome Hambisa Samer Hamidi Mouhanad Hammami Graeme j Hankey Yuantao Hao Hilda l Harb Christopher j l Murray Habtamu Abera Hareri Dejen Yemane Tekle Josep Maria Haro Mohammad Sadegh Hassanvand Rasmus Havmoeller Aliasghar Ahmad Kiadaliri Roderick j Hay Simon i Hay Delia Hendrie Ileana Beatriz Heredia-pi Amanuel Alemu Abajobir Hans w Hoek Masako Horino Girma Temam Shifa Nobuyuki Horita h Dean Hosgood Aung Soe Htet Guoqing hu Alireza Ahmadi Hsiang Huang John j Huang Leticia Avila-burgos Bethany m Huntley Chantal Huynh Kim Moesgaard Iburg Abdullah Sulieman Terkawi Bogdan Vasile Ileanu Kaire Innos Asnake Ararsa Irenso Nader Jahanmehr Mihajlo b Jakovljevic Kedir Yimam Ahmed Euripide Frinel g Arthur Avokpaho Peter James Spencer Lewis James Mehdi Javanbakht Sudha p Jayaraman Azeb Gebresilassie Tesema Achala Upendra Jayatilleke Panniyammakal Jeemon Vivekanand Jha Denny John Catherine Johnson Beatriz Paulina Ayala Quintanilla Sarah c Johnson Muktar Beshir Ahmed Jost b Jonas Knud Juel Zubair Kabir js Thakur Yogeshwar Kalkonde Ritul Kamal Haidong Kan Andre Karch Ashish Awasthi Corine Kakizi Karema Seyed m Karimi Amir Kasaeian Rufus Olusola Akinyemi Nicholas j Kassebaum Anshul Kastor Alan j Thomson Srinivasa Vittal Katikireddi Konstantin Kazanjan Peter Njenga Keiyoro Nebiyu Negussu Ayele Laura Kemmer Andrew Haddon Kemp Andre Pascal Kengne Amene Abebe Kerbo Maia Kereselidze Reed j d Sorensen Tomi f Akinyemiju Taavi Tillmann Chandrasekharan Nair Kesavachandran Yousef Saleh Khader Peter Azzopardi Ibrahim Khalil Abdur Rahman Khan Ejaz Ahmad Khan Gulfaraz Khan Young-ho Khang Abdullah Tawfih Abdullah Khoja Irma Khonelidze Jagdish Khubchandani Tenaw Yimer Tiruye Nadia Akseer Muawiyyah Babale Sufiyan Getiye Dejenu Kibret Daniel Kim Pauline Kim Yun Jin Kim Ruth w Kimokoti Yohannes Kinfu Niranjan Kissoon Miia Kivipelto Yoshihiro Kokubo Hamid Asayesh Huda Omer ba Saleem Anneli Kolk Ziyad Al-aly Dhaval Kolte Jacek a Kopec Soewarta Kosen Parvaiz a Koul ai Koyanagi Michael Kravchenko Sanjay Krishnaswami Kristopher j Krohn Till Bärnighausen Ruoyan Tobe-gai Barthelemy Kuate Defo Burcu Kucuk Bicer Khurshid Alam Ernst j Kuipers Veena s Kulkarni g Anil Kumar Fekede Asefa Kumsa Michael Kutz Hmwe h Kyu Umar Bacha Anton Carl Jonas Lager Marcello Tonelli Aparna Lal Dharmesh Kumar Lal Ratilal Lalloo Noore Alam Tea Lallukka Qing Lan Sinead m Langan Van c Lansingh Alaa Badawi Heidi j Larson Anders Larsson Roman Topor-madry Dennis Odai Laryea Asma Abdul Latif Alicia Elena Beatriz Lawrynowicz Janet l Leasher Sayed Saidul Alam James Leigh Mall Leinsalu Kalkidan Hassen Abate Cheru Tesema Leshargie Janni Leung Ricky Leung Miguel Tortajada Miriam Levi Xiaofeng Liang Stephen s Lim Margaret Lind Shai Linn Zewdie Aderaw Alemu Amitava Banerjee Steven e Lipshultz Patrick Liu Yang Liu Loon-tzian lo Christopher Troeger Giancarlo Logroscino Alan d Lopez Scott a Lorch Paulo a Lotufo Rafael Lozano Aleksandra Barac Raimundas Lunevicius Kefyalew Addis Alene Ronan a Lyons Erlyn Rachelle King Macarayan Mark t Mackay Thomas Truelsen Hassan Magdy Abd el Razek Mohammed Magdy Abd el Razek Mahdi Mahdavi Azeem Majeed Miguel a Barboza Reza Malekzadeh Deborah Carvalho Malta Lorenzo g Mantovani Lily Alexander Tsegahun Manyazewal Chabila c Mapoma Abera Kenay Tura Wagner Marcenes Guy b Marks Neal Marquez Suzanne l Barker-collo Jose Martinez-raga Melvin Barrientos Marzan João Massano Manu Raj Mathur Pallab k Maulik Raghib Ali Mohsen Mazidi Uche s Uchendu Colm Mcalinden John j Mcgrath Lope h Barrero Claire Mcnellan Peter a Meaney Alem Mehari Man Mohan Mehndiratta Toni Meier Alemayehu b Mekonnen Kidanu Gebremariam Meles Thomas Bollyky Kingsley n Ukwaja Syed Danish Ali Rizwan Abdulkader Suliankatchi Ziad a Memish Melkamu Merid Mengesha Desalegn Tadese Mengiste Mubarek Abera Mengistie Bereket Gebremichael Menota George a Mensah Seid Tiku Mereta Atte Meretoja Tuomo j Meretoja Eduardo a Undurraga Sanjay Basu Haftay Berhane Mezgebe Reza Alizadeh-navaei Renata Micha Anoushka Millear Edward j Mills Shawn Minnig Mojde Mirarefin Erkin m Mirrakhimov Charles n Mock Karzan Abdulmuhsin Mohammad Bernhard t Baune Reza Assadi Shafiu Mohammed Sanjay k Mohanty Ala'a Alkerwi Ali h Mokdad Glen Liddell d Mola Mariam Molokhia Lorenzo Monasta Marcella Montico Maziar Moradi-lakeh Kaleab Baye Paula Moraga Chigozie Jesse Uneke Lidia Morawska Rintaro Mori Mark Moses François Alla Ulrich o Mueller Srinivas Murthy Kamarul Imran Musa Jean b Nachega Yibeltal Tebekaw Bayou Chie Nagata Gabriele Nagel Olalekan a Uthman Mohsen Naghavi Aliya Naheed Luigi Naldi Vinay Nangia Peter Allebeck Bruno Ramos Nascimento Ionut Negoi Shahrzad Bazargan-hejazi Sudan Prasad Neupane Charles r Newton Marie ng Job f m Van Boven Frida Namnyak Ngalesoni Josephine Wanjiku Ngunjiri Grant Nguyen Dina Nur Anggraini Ningrum Sandra Nolte Christine Allen Cristiana Abbafati Marika Nomura Ole f Norheim bo Norrving Jean Jacques n Noubiap Rita Van Dingenen Carla Makhlouf Obermeyer Felix Akpojene Ogbo In-hwan oh Anselm Okoro Olanrewaju Oladimeji Neeraj Bedi Andrew Toyin Olagunju Rajaa Al-raddadi Pedro r Olivares Helen e Olsen Bolajoko Olubukunola Olusanya Santosh Varughese Jacob Olusegun Olusanya John Nelson Opio Eyal Oren Alberto Ortiz Ettore Beghi Richard h Osborne Majdi Osman Mayowa o Owolabi Ubai Alsharif Mahesh pa Amanda w Pain Tommi Vasankari Smita Pakhale Elizabeth Palomares Castillo Adrian Pana Yannick Béjot Christina Papachristou Mahboubeh Parsaeian Tejas Patel George c Patton Deepak Paudel Khalid a Altirkawi Vinod k Paul Narayanaswamy Venketasubramanian Neil Pearce David m Pereira Aminu k Bello Rogelio Perez-padilla Fernando Perez-ruiz Norberto Perico Konrad Pesudovs Max Petzold Michael Robert Phillips David m Pigott Elena Alvarez Martin Francesco s Violante Julian David Pillay Jiandong Sun Christine Pinho Suzanne Polinder Constance d Pond v Prakash Manorama Purwar Mostafa Qorbani d Alex Quistberg Amir Radfar Anwar Rafay Sergey k Vladimirov Derrick a Bennett Martin Mckee Nelson Alvis-guzman Kazem Rahimi Vafa Rahimi-movaghar Mahfuzar Rahman Mohammad Hifz ur Rahman Rajesh Kumar Rai Usha Ram Saleem m Rana Zane Rankin Isabela m Bensenor Vasiliy Victorovich Vlassov Paturi Vishnupriya Rao Puja c Rao Azmeraw t Amare Salman Rawaf Maria Albertina Santiago Rego Marissa Reitsma Giuseppe Remuzzi Andre m n n Renzaho Serge Resnikoff Adugnaw Berhane Satar Rezaei Ayalew Astatkie Mohammad Sadegh Rezai Antonio Luiz Pinho Ribeiro Hirbo Shore Roba Erfan Amini Mohammad Bagher Rokni Luca Ronfani Gholamreza Roshandel Gregory a Roth Eduardo Bernabé Dietrich Rothenbacher Nawal k Roy Stein Emil Vollset Perminder s Sachdev Ben Benasco Sackey Mohammad Yahya Saeedi Saeid Safiri Walid Ammar Rajesh Sagar Mohammad Ali Sahraian Oscar Alberto Bernal Muhammad Muhammad Saleh Joshua a Salomon Abdallah m Samy Theo Vos Juan Ramon Sanabria Maria Dolores Sanchez-niño Logan Sandar Itamar s Santos João Vasco Santos Joshu Amo-adjei Addisu Shunu Beyene Milena m Santric Milicevic Rodrigo Sarmiento-suarez Benn Sartorius Maheswar Satpathy Joseph a Wagner Miloje Savic Monika Sawhney Mete i Saylan Ben Schöttker Aletta e Schutte Ryan Mbarber David c Schwebel Yaw Ampem Amoako Soraya Seedat Abdulbasit Musa Seid Canaan Negash Seifu Tolassa Wakayo Sadaf g Sepanlou Berrin Serdar Edson e Servan-mori Tesfaye Setegn Kaja m Abbas Katya Anne Shackelford Amira Shaheen Saeid Shahraz Benjamin o Anderson Masood Ali Shaikh Marina Shakh-nazarova Stephen g Waller Mansour Shamsipour Sheikh Mohammed Shariful Islam Jayendra Sharma Tariku Jibat Beyene Rajesh Sharma Jun She Sara Sheikhbahaei Jiabin Shen Peilin Shi Sofia Androudi Mika Shigematsu Judd l Walson Min-jeong Shin Rahman Shiri Zulfiqar a Bhutta Haitham Shoman Mark g Shrime Ephrem Lejore Sibamo Sibamo Inga Dora Sigfusdottir Diego Augusto Santos Silva Dayane Gabriele Alves Silveira Shireen Sindi Hossein Ansari Haidong Wang Abhishek Singh Patrick Sur Jasvinder a Singh om Prakash Singh Prashant Kumar Singh Virendra Singh Abiy Hiruye Sinke Aklilu Endalamaw Sinshaw Vegard Skirbekk Karen Sliwa Alison Smith Yuan-pang Wang Sibhatu Biadgilign Mustafa Geleto Ansha Eugene Sobngwi Samir Soneji Joan b Soriano Tatiane Cristina Moraes Sousa Luciano a Sposato David a Watkins Elisabete Weiderpass Tesfay Mehari Atey Robert g Weintraub Boris Bikbov Chi-pang Wen Andrea Werdecker Joshua Wesana Ronny Westerman Harvey a Whiteford James d Wilkinson Charles Shey Wiysonge Belete Getahun Woldeyes Charles d a Wolfe Suleman Atique Sait Mentes Birlik Sungho Won Abdulhalik Workicho Shimelash Bitew Workie Mamo Wubshet Denis Xavier Gelin xu Ajit Kumar Yadav Mohsen Yaghoubi Bereket Yakob Lijing l Yan Charles Birungi Niguse Tadele Atnafu Yuichiro Yano Mehdi Yaseri Hassen Hamid Yimam Paul Yip Naohiro Yonemoto Stan Biryukov Donal Bisanzio Habtamu Mellie Bizuayehu Dipan Bose Foad Abd-allah Michael Brainin Soumya Swaminathan Michael Brauer Alexandra Brazinova Nicholas j k Breitborde Hermann Brenner Zahid a Butt Rosario Cárdenas Lucero Cahuana-hurtado Ismael Ricardo Campos-nonato Josip Car Abdishakur m Abdulle Johan Ärnlöv Juan Jesus Carrero Daniel Casey Valeria Caso Carlos a Castañeda-orjuela Jacqueline Castillo Rivas Ferrán Catalá-lópez Pedro Cecilio Kelly Cercy Fiona j Charlson Alan z Chen Bryan l Sykes Ahmed Abdulahi Abdurahman |
dc.subject.por.fl_str_mv |
Global Burden of Disease Mortality Personal Health Carga Global da Doença Registros de Mortalidade Registros de Saúde Pessoal |
topic |
Global Burden of Disease Mortality Personal Health Carga Global da Doença Registros de Mortalidade Registros de Saúde Pessoal |
description |
Background National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015.Methods We mapped the most widely used list of causes amenable to personal health care developed by Nolte and McKee to 32 GBD causes. We accounted for variations in cause of death certification and misclassifications through the extensive data standardisation processes and redistribution algorithms developed for GBD. To isolate the effects of personal health-care access and quality, we risk-standardised cause-specific mortality rates for each geography-year by removing the joint effects of local environmental and behavioural risks, and adding back the global levels of risk exposure as estimated for GBD 2015. We employed principal component analysis to create a single, interpretable summary measure–the Healthcare Quality and Access (HAQ) Index–on a scale of 0 to 100. The HAQ Index showed strong convergence validity as compared with other health-system indicators, including health expenditure per capita (r=0·88), an index of 11 universal health coverage interventions (r=0·83), and human resources for health per 1000 (r=0·77). We used free disposal hull analysis with bootstrapping to produce a frontier based on the relationship between the HAQ Index and the Socio-demographic Index (SDI), a measure of overall development consisting of income per capita, average years of education, and total fertility rates. This frontier allowed us to better quantify the maximum levels of personal health-care access and quality achieved across the development spectrum, and pinpoint geographies where gaps between observed and potential levels have narrowed or widened over time.Findings Between 1990 and 2015, nearly all countries and territories saw their HAQ Index values improve; nonetheless, the difference between the highest and lowest observed HAQ Index was larger in 2015 than in 1990, ranging from 28·6 to 94·6. Of 195 geographies, 167 had statistically significant increases in HAQ Index levels since 1990, with South Korea, Turkey, Peru, China, and the Maldives recording among the largest gains by 2015. Performance on the HAQ Index and individual causes showed distinct patterns by region and level of development, yet substantial heterogeneities emerged for several causes, including cancers in highest-SDI countries; chronic kidney disease, diabetes, diarrhoeal diseases, and lower respiratory infections among middle-SDI countries; and measles and tetanus among lowest-SDI countries. While the global HAQ Index average rose from 40·7 (95% uncertainty interval, 39·0–42·8) in 1990 to 53·7 (52·2–55·4) in 2015, far less progress occurred in narrowing the gap between observed HAQ Index values and maximum levels achieved; at the global level, the difference between the observed and frontier HAQ Index only decreased from 21·2 in 1990 to 20·1 in 2015. If every country and territory had achieved the highest observed HAQ Index by their corresponding level of SDI, the global average would have been 73·8 in 2015. Several countries, particularly in eastern and western sub-Saharan Africa, reached HAQ Index values similar to or beyond their development levels, whereas others, namely in southern sub-Saharan Africa, the Middle East, and south Asia, lagged behind what geographies of similar development attained between 1990 and 2015. Interpretation This novel extension of the GBD Study shows the untapped potential for personal health-care access and quality improvement across the development spectrum. Amid substantive advances in personal health care at the national level, heterogeneous patterns for individual causes in given countries or territories suggest that few places have consistently achieved optimal health-care access and quality across health-system functions and therapeutic areas. This is especially evident in middle-SDI countries, many of which have recently undergone or are currently experiencing epidemiological transitions. The HAQ Index, if paired with other measures of health-system haracteristics such as intervention coverage, could provide a robust avenue for tracking progress on universal health coverage and identifying local priorities for strengthening personal health-care quality and access throughout the world. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-07-15 2023-06-28T23:14:55Z 2023-06-28T23:14:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.1016/S0140-6736(17)30818-8 01406736 http://hdl.handle.net/1843/55521 https://orcid.org/0000-0001-5689-3870 |
url |
https://doi.org/10.1016/S0140-6736(17)30818-8 http://hdl.handle.net/1843/55521 https://orcid.org/0000-0001-5689-3870 |
identifier_str_mv |
01406736 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
The Lancet |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais Brasil ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA MED - DEPARTAMENTO DE CLÍNICA MÉDICA MED - DEPARTAMENTO DE PEDIATRIA UFMG |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais Brasil ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA MED - DEPARTAMENTO DE CLÍNICA MÉDICA MED - DEPARTAMENTO DE PEDIATRIA UFMG |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Repositório Institucional da UFMG |
collection |
Repositório Institucional da UFMG |
repository.name.fl_str_mv |
Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
repositorio@ufmg.br |
_version_ |
1816829655071588352 |