High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFMG |
| Texto Completo: | https://doi.org/10.1590/1516-3180.2021.0015.r1.14062021 http://hdl.handle.net/1843/60539 https://orcid.org/0000-0001-9459-2294 |
Resumo: | FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais |
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2023-11-06T21:11:21Z2023-11-06T21:11:21Z20221402199206https://doi.org/10.1590/1516-3180.2021.0015.r1.140620211516-3180http://hdl.handle.net/1843/60539https://orcid.org/0000-0001-9459-2294FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisBACKGROUND: Gastrointestinal (GI) symptoms are frequent complaints from individuals with nonalcoholic fatty liver disease (NAFLD). Dyspepsia is a universal clinical symptom and is among the most common GI complaints observed in the general population, but its prevalence in the population with NAFLD has not been previously investigated. OBJECTIVE: To compare the prevalence of functional dyspepsia (FD) between patients with NAFLD and controls without liver disease. DESIGN AND SETTING: Cross-sectional study at the Outpatient Liver Clinic, University Hospital, Belo Horizonte, Brazil. METHODS: We included 96 NAFLD patients and 105 controls without liver disease. All participants were assessed for GI symptoms in accordance with the Rome III criteria. Evaluation methods included a questionnaire for FD (validated in Brazil), laboratory tests and upper GI endoscopy. RESULTS: Mean age and sex were similar between the groups. The NAFLD group presented higher frequency of proton-pump inhibitor usage (31.3% vs 4.8%; P < 0.001) and prevalence of FD (25.0% versus 12.4%; P = 0.021). The symptom frequencies were as follows: postprandial distress, 22.9% versus 11.4% (P = 0.030); postprandial fullness, 18.8% versus 10.5% (P = 0.095); early satiation, 8.3% versus 5.7% (P = 0.466); and epigastric pain or burning, 18.8% versus 5.7% (P = 0.004), in NAFLD patients and controls, respectively. Multivariate analysis demonstrated that female sex (odds ratio, OR 6.97; 95% confidence interval, CI: 1.51-32.12; P = 0.013) and NAFLD diagnosis (OR 2.45; 95% CI: 1.14-5.27; P = 0.021) were independently associated with FD occurrence. CONCLUSION: FD occurs more frequently in individuals with NAFLD than in controls without hepatic disease.engUniversidade Federal de Minas GeraisUFMGBrasilMED - DEPARTAMENTO DE CLÍNICA MÉDICASão Paulo Medical JournalGastroenteropatiasHepatopatia gordurosa não alcoólicaDispepsiaObesidadeDiabetes MellitusFunctional gastrointestinal disordersNAFLDIndigestionBody weightHigh prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.scielo.br/j/spmj/a/FFW8kwCpLVQngqXQCSdQPQS/?lang=enÉrika Cristina LimaClaudia Alves CoutoMaria do Carmo Friche PassosSilvia Marinho FerollaRaissa Soares Neves da CostaQuelson Coelho LisboaLucas Ismael Dias PereiraMateus Jorge NardelliVitor Nunes ArantesTeresa Cristina de Abreu Ferrariapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/60539/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALHigh prevalence of functional dyspepsia in nonalcoholic fatty liver disease_a cross-sectional study.pdfHigh prevalence of functional dyspepsia in nonalcoholic fatty liver disease_a cross-sectional study.pdfapplication/pdf581278https://repositorio.ufmg.br/bitstream/1843/60539/2/High%20prevalence%20of%20functional%20dyspepsia%20in%20nonalcoholic%20fatty%20liver%20disease_a%20cross-sectional%20study.pdfbb23d1d6c2f503fd7f2f37de021ef11bMD521843/605392023-11-06 18:11:21.211oai:repositorio.ufmg.br:1843/60539Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-11-06T21:11:21Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
| dc.title.pt_BR.fl_str_mv |
High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study |
| title |
High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study |
| spellingShingle |
High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study Érika Cristina Lima Functional gastrointestinal disorders NAFLD Indigestion Body weight Gastroenteropatias Hepatopatia gordurosa não alcoólica Dispepsia Obesidade Diabetes Mellitus |
| title_short |
High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study |
| title_full |
High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study |
| title_fullStr |
High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study |
| title_full_unstemmed |
High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study |
| title_sort |
High prevalence of functional dyspepsia in nonalcoholic fatty liver disease: a cross-sectional study |
| author |
Érika Cristina Lima |
| author_facet |
Érika Cristina Lima Claudia Alves Couto Maria do Carmo Friche Passos Silvia Marinho Ferolla Raissa Soares Neves da Costa Quelson Coelho Lisboa Lucas Ismael Dias Pereira Mateus Jorge Nardelli Vitor Nunes Arantes Teresa Cristina de Abreu Ferrari |
| author_role |
author |
| author2 |
Claudia Alves Couto Maria do Carmo Friche Passos Silvia Marinho Ferolla Raissa Soares Neves da Costa Quelson Coelho Lisboa Lucas Ismael Dias Pereira Mateus Jorge Nardelli Vitor Nunes Arantes Teresa Cristina de Abreu Ferrari |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Érika Cristina Lima Claudia Alves Couto Maria do Carmo Friche Passos Silvia Marinho Ferolla Raissa Soares Neves da Costa Quelson Coelho Lisboa Lucas Ismael Dias Pereira Mateus Jorge Nardelli Vitor Nunes Arantes Teresa Cristina de Abreu Ferrari |
| dc.subject.por.fl_str_mv |
Functional gastrointestinal disorders NAFLD Indigestion Body weight |
| topic |
Functional gastrointestinal disorders NAFLD Indigestion Body weight Gastroenteropatias Hepatopatia gordurosa não alcoólica Dispepsia Obesidade Diabetes Mellitus |
| dc.subject.other.pt_BR.fl_str_mv |
Gastroenteropatias Hepatopatia gordurosa não alcoólica Dispepsia Obesidade Diabetes Mellitus |
| description |
FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais |
| publishDate |
2022 |
| dc.date.issued.fl_str_mv |
2022 |
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2023-11-06T21:11:21Z |
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2023-11-06T21:11:21Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/1843/60539 |
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https://doi.org/10.1590/1516-3180.2021.0015.r1.14062021 |
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1516-3180 |
| dc.identifier.orcid.pt_BR.fl_str_mv |
https://orcid.org/0000-0001-9459-2294 |
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https://doi.org/10.1590/1516-3180.2021.0015.r1.14062021 http://hdl.handle.net/1843/60539 https://orcid.org/0000-0001-9459-2294 |
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1516-3180 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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São Paulo Medical Journal |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Universidade Federal de Minas Gerais |
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UFMG |
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Brasil |
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MED - DEPARTAMENTO DE CLÍNICA MÉDICA |
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Universidade Federal de Minas Gerais |
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reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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