Immune repercussions in patients with functional dyspepsia: A systematic review
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/17785 |
Resumo: | Introduction: Functional Dyspepsia (FD) is a chronic or intermittent stomach disorder due to loss of homeostatic balance, being part of Functional Gastrointestinal Diseases (FGIDs). Several factors can be involved with the disease and its immune repercussions. Objective: To evaluate, in patients with Functional Dyspepsia, the risk of immunological repercussions. Method: Systematic Literature Review. The data search strategy used was obtained through two databases: Biblioteca Virtual em Saúde (BVS) and PubMed. The guiding question follows the acronym PO, with P being patients with FD and O as immune repercussions. A combination of descriptors was used: “Dyspepsia” AND “Immune System”. The inclusion criteria used were any year of publication, in Portuguese and English, full online articles and Cohort and Cross-sectional studies that address the PO issue. After the initial identification of the articles, they were read in pairs and selected according to eligibility criteria. Results: Five articles were selected, with Cohort and Cross-sectional studies. In patients with FD, there is a greater probability of developing certain diseases caused by immune dysregulation, such as atopy and mood disorders. One of the main causal factors is inflammation caused by infections, in which stress has led to an increase in inflammatory cytokines throughout the body, which can lead to allergic conditions and neurological disorders. Conclusion: There was evidence of a correlation between FD and the onset of atopy and later mood disorders. However, it is necessary to invest in more articles to better elucidate the overlap between such diseases. |
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Immune repercussions in patients with functional dyspepsia: A systematic reviewRepercusiones inmunitarias en pacientes con dispepsia funcional: Una revisión sistemáticaRepercussões imunes em pacientes com dispepsia funcional: Uma revisão sistemáticaDyspepsiaImmune SystemMood DisordersGastrointestinal diseases.DispepsiaSistema ImuneTranstornos de HumorGastroenteropatias.DispepsiaSistema inmunológicoTrastornos del estado de ánimoEnfermedades gastrointestinales.Introduction: Functional Dyspepsia (FD) is a chronic or intermittent stomach disorder due to loss of homeostatic balance, being part of Functional Gastrointestinal Diseases (FGIDs). Several factors can be involved with the disease and its immune repercussions. Objective: To evaluate, in patients with Functional Dyspepsia, the risk of immunological repercussions. Method: Systematic Literature Review. The data search strategy used was obtained through two databases: Biblioteca Virtual em Saúde (BVS) and PubMed. The guiding question follows the acronym PO, with P being patients with FD and O as immune repercussions. A combination of descriptors was used: “Dyspepsia” AND “Immune System”. The inclusion criteria used were any year of publication, in Portuguese and English, full online articles and Cohort and Cross-sectional studies that address the PO issue. After the initial identification of the articles, they were read in pairs and selected according to eligibility criteria. Results: Five articles were selected, with Cohort and Cross-sectional studies. In patients with FD, there is a greater probability of developing certain diseases caused by immune dysregulation, such as atopy and mood disorders. One of the main causal factors is inflammation caused by infections, in which stress has led to an increase in inflammatory cytokines throughout the body, which can lead to allergic conditions and neurological disorders. Conclusion: There was evidence of a correlation between FD and the onset of atopy and later mood disorders. However, it is necessary to invest in more articles to better elucidate the overlap between such diseases.Introducción: La dispepsia funcional (DF) es un trastorno estomacal crónico o intermitente debido a la pérdida del equilibrio homeostático, que forma parte de las Enfermedades Gastrointestinales Funcionales (TFGI). Varios factores pueden estar involucrados con la enfermedad y sus repercusiones inmunológicas. Objetivo: evaluar, en pacientes con dispepsia funcional, el riesgo de repercusión inmunitaria. Método: Revisión sistemática de la literatura. Los datos se buscaron en dos bases de datos: Biblioteca Virtual em Saúde (BVS) y PubMed. La pregunta orientadora sigue el acrónimo PO, siendo P los pacientes con DF y O las repercusiones inmunes. Se utilizó la combinación de descriptores: “Dyspepsia” AND “Immune System”. Los criterios de inclusión utilizados fueron cualquier año de publicación, en portugués e inglés, artículos completos en línea y estudios de cohortes y transversales que abordan el tema de las OP. Tras la identificación inicial de los artículos, se leyeron por parejas y se seleccionaron según criterios de elegibilidad. Resultados: Se seleccionaron cinco artículos, con estudios de cohortes y transversales. En los pacientes con EF existe una mayor probabilidad de desarrollar determinadas enfermedades provocadas por una desregulación inmunitaria, como atopia, infecciones y trastornos del estado de ánimo. Uno de los principales factores causales es la inflamación causada por infecciones, en la que el estrés conduce a un aumento de citocinas inflamatorias en todo el cuerpo, lo que puede provocar afecciones alérgicas y trastornos neurológicos. Conclusión: hubo evidencia de una correlación entre DF y la aparición de atopia y trastornos posteriores del estado de ánimo. Sin embargo, es necesario invertir en más artículos para dilucidar mejor la superposición entre estas enfermedades.Introdução: A Dispepsia Funcional (DF) é um distúrbio crônico ou intermitente do estômago pela perda do equilíbrio homeostático, fazendo parte das Doenças Gastrointestinais Funcionais (FGIDs). Vários fatores podem estar envolvidos com a doença e suas repercussões imunes. Objetivo: Avaliar, em pacientes com Dispepsia Funcional, qual o risco de repercussões imunes. Método: Revisão Sistemática da Literatura. A busca de dados ocorreu em duas bases: Biblioteca Virtual em Saúde (BVS) e PubMed. A pergunta norteadora segue o acrônimo PO, sendo P os pacientes com DF e O as repercussões imunes. Utilizou-se a combinação dos descritores: “Dyspepsia” AND “Immune System”. Os critérios de inclusão utilizados foram qualquer ano de publicação, em português e inglês, artigos completos online e estudos de Coorte e Transversais que abordem a questão PO. Após a identificação inicial dos artigos, foi realizada leitura aos pares e seleção conforme critérios de elegibilidade. Resultados: Foram selecionados cinco artigos, com estudos do tipo Coorte e Transversais. Em pacientes com DF, há maior probabilidade de desenvolver determinadas doenças pela desregulação imunológica causada, como atopias, infecções e transtornos de humor. Um dos principais fatores causais é a inflamação acarretada por infecções, em que o estresse leva ao aumento das citocinas inflamatórias pelo organismo, que pode levar a quadros alérgicos e disfunções neurológicas. Conclusão: Evidenciou-se uma correlação entre a DF e o surgimento de atopias e transtornos de humor posteriores. Contudo, faz-se necessário investir em mais artigos para elucidar melhor a sobreposição entre tais doenças.Research, Society and Development2021-07-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1778510.33448/rsd-v10i9.17785Research, Society and Development; Vol. 10 No. 9; e17810917785Research, Society and Development; Vol. 10 Núm. 9; e17810917785Research, Society and Development; v. 10 n. 9; e178109177852525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/17785/16029Copyright (c) 2021 Natálhya Furtado Oliveira Nobre; Matusalém Marcelino Cândido; Larissa Mercielly Nóbrega Medeiros; Milena Nunes Alves Sousahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessNobre, Natálhya Furtado Oliveira Cândido, Matusalém Marcelino Medeiros, Larissa Mercielly Nóbrega Sousa, Milena Nunes Alves 2021-09-12T14:28:06Zoai:ojs.pkp.sfu.ca:article/17785Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:38:03.915210Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Immune repercussions in patients with functional dyspepsia: A systematic review Repercusiones inmunitarias en pacientes con dispepsia funcional: Una revisión sistemática Repercussões imunes em pacientes com dispepsia funcional: Uma revisão sistemática |
title |
Immune repercussions in patients with functional dyspepsia: A systematic review |
spellingShingle |
Immune repercussions in patients with functional dyspepsia: A systematic review Nobre, Natálhya Furtado Oliveira Dyspepsia Immune System Mood Disorders Gastrointestinal diseases. Dispepsia Sistema Imune Transtornos de Humor Gastroenteropatias. Dispepsia Sistema inmunológico Trastornos del estado de ánimo Enfermedades gastrointestinales. |
title_short |
Immune repercussions in patients with functional dyspepsia: A systematic review |
title_full |
Immune repercussions in patients with functional dyspepsia: A systematic review |
title_fullStr |
Immune repercussions in patients with functional dyspepsia: A systematic review |
title_full_unstemmed |
Immune repercussions in patients with functional dyspepsia: A systematic review |
title_sort |
Immune repercussions in patients with functional dyspepsia: A systematic review |
author |
Nobre, Natálhya Furtado Oliveira |
author_facet |
Nobre, Natálhya Furtado Oliveira Cândido, Matusalém Marcelino Medeiros, Larissa Mercielly Nóbrega Sousa, Milena Nunes Alves |
author_role |
author |
author2 |
Cândido, Matusalém Marcelino Medeiros, Larissa Mercielly Nóbrega Sousa, Milena Nunes Alves |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Nobre, Natálhya Furtado Oliveira Cândido, Matusalém Marcelino Medeiros, Larissa Mercielly Nóbrega Sousa, Milena Nunes Alves |
dc.subject.por.fl_str_mv |
Dyspepsia Immune System Mood Disorders Gastrointestinal diseases. Dispepsia Sistema Imune Transtornos de Humor Gastroenteropatias. Dispepsia Sistema inmunológico Trastornos del estado de ánimo Enfermedades gastrointestinales. |
topic |
Dyspepsia Immune System Mood Disorders Gastrointestinal diseases. Dispepsia Sistema Imune Transtornos de Humor Gastroenteropatias. Dispepsia Sistema inmunológico Trastornos del estado de ánimo Enfermedades gastrointestinales. |
description |
Introduction: Functional Dyspepsia (FD) is a chronic or intermittent stomach disorder due to loss of homeostatic balance, being part of Functional Gastrointestinal Diseases (FGIDs). Several factors can be involved with the disease and its immune repercussions. Objective: To evaluate, in patients with Functional Dyspepsia, the risk of immunological repercussions. Method: Systematic Literature Review. The data search strategy used was obtained through two databases: Biblioteca Virtual em Saúde (BVS) and PubMed. The guiding question follows the acronym PO, with P being patients with FD and O as immune repercussions. A combination of descriptors was used: “Dyspepsia” AND “Immune System”. The inclusion criteria used were any year of publication, in Portuguese and English, full online articles and Cohort and Cross-sectional studies that address the PO issue. After the initial identification of the articles, they were read in pairs and selected according to eligibility criteria. Results: Five articles were selected, with Cohort and Cross-sectional studies. In patients with FD, there is a greater probability of developing certain diseases caused by immune dysregulation, such as atopy and mood disorders. One of the main causal factors is inflammation caused by infections, in which stress has led to an increase in inflammatory cytokines throughout the body, which can lead to allergic conditions and neurological disorders. Conclusion: There was evidence of a correlation between FD and the onset of atopy and later mood disorders. However, it is necessary to invest in more articles to better elucidate the overlap between such diseases. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-07-23 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/17785 10.33448/rsd-v10i9.17785 |
url |
https://rsdjournal.org/index.php/rsd/article/view/17785 |
identifier_str_mv |
10.33448/rsd-v10i9.17785 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/17785/16029 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 9; e17810917785 Research, Society and Development; Vol. 10 Núm. 9; e17810917785 Research, Society and Development; v. 10 n. 9; e17810917785 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052833195884544 |