Prevalence of HIV-1/HTLV-1 co-infection and behavioral risk among people living with HIV in Belo Horizonte, Brazil

• Autor(a) principal: Poliane Cristina Vertêlo
• Data de Publicação: 2023
• Outros Autores: Alexandre Braga Miranda, Ludimila Labanca, Ana Lúcia Borges Starling, Cláudio Daniel Cerdeira, Carlos Felipe Nogueira, Denise Utscha Gonçalves
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMG
• Texto Completo: https://revistas.unc.edu.ar/index.php/RSD/article/view/38078; http://hdl.handle.net/1843/61367
• topic: HTLV-1; HIV-1; Coinfection; Behavior; Comportamento; Coinfecção; HIV-1; Vírus Linfotrópico T Tipo 1 Humano

Objective: To analyze the prevalence of HIV-1 and HTLV-1 co-infection and risk behavioral for sexually transmitted infections (STIs) and the quality of life among people living with HIV-1 (PL-HIV-1). Methods: 985 PL-HIV-1 in Belo Horizonte (Brazil) underwent serologic immunoassay screening for HTLV-1. Fifteen people confirmed (Western blot) for HIV-1/HTLV-1 co-infection (HIV-1/HTLV-1 group) were then compared to 30 HIV-1 (HIV-1 group) and 30 HTLV-1 (HTLV-1 group) patients, matched groups for biological sex and age, and was analyzed the sociodemographic status/quality of life and risk/behavioral factors for STIs. Results: The prevalence of HIV-1/HTLV-1 co-infection was 1.5%. The average age of the three groups was 57 (± 11) years old, with 9 and 18 (60%) women within the HIV-1/HTLV-1 and HIV-1 or HTLV-1 groups, respectively. Heterosexual orientation predominated within the three groups. The HIV-1/HTLV-1 and HIV-1 groups had most no fixed partner (p = 0.013), were single (p = 0.001) and referred condom use (p = 0.025). Most the HTLV-1 group had fixed partner, were married, and did not use condom (p = 0.025). Among other STIs, syphilis was common within the HIV-1/HTLV-1 (34%) and HIV-1 (17%) groups, and gonorrhea (13%) within the HTLV-1 group. Intravenous drug use (IDU) in the HIV-1 group was associated with co-infection (p = 0.038), and the quality of life differed among the groups. Conclusions: HIV-1 and HIV-1/HTLV-1 groups had different risk behaviors than HTLV-1 group. The measures to prevent the spread of HIV-1 and HTLV-1 should also highlight IDU in PL-HIV-1 and condom use in people living with HTLV-1.