Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients

Detalhes bibliográficos
Autor(a) principal: Maria Luisa Gois da Fonsêca
Data de Publicação: 2022
Outros Autores: Raul Nunes Galvarro Vianna, Anna Christina Higino Rocha, Antonio Marcelo Barbante Casella, Arnaldo Cialdini, Cristina Mucciolli, Daniela Socci da Costa, Daniel Lucena, Daniel Vítor de Vasconcelos Santos, Eduardo Morizot, Elaine Castro, Ever E. C. Rodriguez, Felipe Telöken Diligenti, Fernanda B. O. Porto, Heloisa Nascimento, Joyce Hisae Yamamoto, Juliana Lambert Oréfice, Lilia R. P. Muralha, Luciana Peixoto Finamor, Maria Auxiliadora Monteiro Frazão, Mário Martins dos Santos Motta, Mário J. Nóbrega, Moysés E. Zajdenweber, Remo T. Moraes, Rodrigo L. Meirelles, Sidney Rocha Lemos, Wilton Feitosa de Araújo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1186/s40942-021-00353-1
http://hdl.handle.net/1843/61364
Resumo: Background: Birdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical fndings and the evolution of BRC in Brazilian patients. Methods: This retrospective cohort multicenter nationwide study was performed by analyzing the records of patients with BRC diagnoses from Brazilian ophthalmological centers from April 1995 to May 2020. Results: Forty patients (80 eyes) with a diagnosis of BRC were evaluated. The mean age was 53 years, and there was no sex predominance. All tested patients (34/40) were positive for HLA-A29. The diagnosis of BRC was made following the Levinson et al. criteria, and all ancillary tests were performed to exclude diferential diagnoses. Clinical signs and symptoms, such as complications and treatment, were described. Conclusions: BRC evolution in Brazilian patients seems to have some peculiarities that diverge from the published literature available about Caucasians, as AS infammation is higher in this population.
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spelling 2023-11-24T19:35:23Z2023-11-24T19:35:23Z20228https://doi.org/10.1186/s40942-021-00353-12056-9920http://hdl.handle.net/1843/61364Background: Birdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical fndings and the evolution of BRC in Brazilian patients. Methods: This retrospective cohort multicenter nationwide study was performed by analyzing the records of patients with BRC diagnoses from Brazilian ophthalmological centers from April 1995 to May 2020. Results: Forty patients (80 eyes) with a diagnosis of BRC were evaluated. The mean age was 53 years, and there was no sex predominance. All tested patients (34/40) were positive for HLA-A29. The diagnosis of BRC was made following the Levinson et al. criteria, and all ancillary tests were performed to exclude diferential diagnoses. Clinical signs and symptoms, such as complications and treatment, were described. Conclusions: BRC evolution in Brazilian patients seems to have some peculiarities that diverge from the published literature available about Caucasians, as AS infammation is higher in this population.Antecedentes: A retinocoroidite de Birdshot (BRC) é uma uveíte bilateral rara e crônica encontrada principalmente em caucasianos. Como poucos dados estão disponíveis sobre a evolução clínica do CBR em pacientes hispânicos, nosso objetivo foi relatar os achados clínicos e a evolução do CBR em pacientes brasileiros. Métodos: Este estudo de coorte retrospectivo multicêntrico de âmbito nacional foi realizado por meio da análise de prontuários de pacientes com diagnóstico de CBR de centros oftalmológicos brasileiros de abril de 1995 a maio de 2020. Resultados: Foram avaliados 40 pacientes (80 olhos) com diagnóstico de CBR. A média de idade foi de 53 anos e não houve predomínio de sexo. Todos os pacientes testados (34/40) foram positivos para HLA-A29. O diagnóstico de BRC foi feito seguindo Levinson et al. critérios, e todos os exames complementares foram realizados para excluir diagnósticos diferenciais. Sinais e sintomas clínicos, como complicações e tratamento, foram descritos. Conclusões: A evolução do CBR em pacientes brasileiros parece apresentar algumas peculiaridades que divergem da literatura publicada disponível sobre caucasianos, uma vez que a inflamação da EA é maior nesta população.engUniversidade Federal de Minas GeraisUFMGBrasilHCL - HOSPITAL DAS CLINICASMED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIAInternational Journal of Retina and VitreousCoriorretinopatia de BirdshotRetinaUveíteBirdshot retinochoroiditisRetinaUveitisBirdshot retinochoroiditis in Brazil: a multicenter study of 40 patientsRetinocoroidite de Birdshot no Brasil: estudo multicêntrico com 40 pacientesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://journalretinavitreous.biomedcentral.com/articles/10.1186/s40942-021-00353-1Maria Luisa Gois da FonsêcaRaul Nunes Galvarro ViannaAnna Christina Higino RochaAntonio Marcelo Barbante CasellaArnaldo CialdiniCristina MucciolliDaniela Socci da CostaDaniel LucenaDaniel Vítor de Vasconcelos SantosEduardo MorizotElaine CastroEver E. C. RodriguezFelipe Telöken DiligentiFernanda B. O. PortoHeloisa NascimentoJoyce Hisae YamamotoJuliana Lambert OréficeLilia R. P. MuralhaLuciana Peixoto FinamorMaria Auxiliadora Monteiro FrazãoMário Martins dos Santos MottaMário J. NóbregaMoysés E. ZajdenweberRemo T. MoraesRodrigo L. MeirellesSidney Rocha LemosWilton Feitosa de Araújoapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/61364/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALBirdshot retinochoroiditis in Brazil_ a multicenter review of 40 patients.pdfBirdshot retinochoroiditis in Brazil_ a multicenter review of 40 patients.pdfapplication/pdf172559https://repositorio.ufmg.br/bitstream/1843/61364/2/Birdshot%20retinochoroiditis%20in%20Brazil_%20a%20multicenter%20review%20of%2040%20patients.pdf41b199f7046396315c7902533f3c105dMD521843/613642023-11-24 16:35:23.469oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-11-24T19:35:23Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
dc.title.alternative.pt_BR.fl_str_mv Retinocoroidite de Birdshot no Brasil: estudo multicêntrico com 40 pacientes
title Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
spellingShingle Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
Maria Luisa Gois da Fonsêca
Birdshot retinochoroiditis
Retina
Uveitis
Coriorretinopatia de Birdshot
Retina
Uveíte
title_short Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
title_full Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
title_fullStr Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
title_full_unstemmed Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
title_sort Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
author Maria Luisa Gois da Fonsêca
author_facet Maria Luisa Gois da Fonsêca
Raul Nunes Galvarro Vianna
Anna Christina Higino Rocha
Antonio Marcelo Barbante Casella
Arnaldo Cialdini
Cristina Mucciolli
Daniela Socci da Costa
Daniel Lucena
Daniel Vítor de Vasconcelos Santos
Eduardo Morizot
Elaine Castro
Ever E. C. Rodriguez
Felipe Telöken Diligenti
Fernanda B. O. Porto
Heloisa Nascimento
Joyce Hisae Yamamoto
Juliana Lambert Oréfice
Lilia R. P. Muralha
Luciana Peixoto Finamor
Maria Auxiliadora Monteiro Frazão
Mário Martins dos Santos Motta
Mário J. Nóbrega
Moysés E. Zajdenweber
Remo T. Moraes
Rodrigo L. Meirelles
Sidney Rocha Lemos
Wilton Feitosa de Araújo
author_role author
author2 Raul Nunes Galvarro Vianna
Anna Christina Higino Rocha
Antonio Marcelo Barbante Casella
Arnaldo Cialdini
Cristina Mucciolli
Daniela Socci da Costa
Daniel Lucena
Daniel Vítor de Vasconcelos Santos
Eduardo Morizot
Elaine Castro
Ever E. C. Rodriguez
Felipe Telöken Diligenti
Fernanda B. O. Porto
Heloisa Nascimento
Joyce Hisae Yamamoto
Juliana Lambert Oréfice
Lilia R. P. Muralha
Luciana Peixoto Finamor
Maria Auxiliadora Monteiro Frazão
Mário Martins dos Santos Motta
Mário J. Nóbrega
Moysés E. Zajdenweber
Remo T. Moraes
Rodrigo L. Meirelles
Sidney Rocha Lemos
Wilton Feitosa de Araújo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Maria Luisa Gois da Fonsêca
Raul Nunes Galvarro Vianna
Anna Christina Higino Rocha
Antonio Marcelo Barbante Casella
Arnaldo Cialdini
Cristina Mucciolli
Daniela Socci da Costa
Daniel Lucena
Daniel Vítor de Vasconcelos Santos
Eduardo Morizot
Elaine Castro
Ever E. C. Rodriguez
Felipe Telöken Diligenti
Fernanda B. O. Porto
Heloisa Nascimento
Joyce Hisae Yamamoto
Juliana Lambert Oréfice
Lilia R. P. Muralha
Luciana Peixoto Finamor
Maria Auxiliadora Monteiro Frazão
Mário Martins dos Santos Motta
Mário J. Nóbrega
Moysés E. Zajdenweber
Remo T. Moraes
Rodrigo L. Meirelles
Sidney Rocha Lemos
Wilton Feitosa de Araújo
dc.subject.por.fl_str_mv Birdshot retinochoroiditis
Retina
Uveitis
topic Birdshot retinochoroiditis
Retina
Uveitis
Coriorretinopatia de Birdshot
Retina
Uveíte
dc.subject.other.pt_BR.fl_str_mv Coriorretinopatia de Birdshot
Retina
Uveíte
description Background: Birdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical fndings and the evolution of BRC in Brazilian patients. Methods: This retrospective cohort multicenter nationwide study was performed by analyzing the records of patients with BRC diagnoses from Brazilian ophthalmological centers from April 1995 to May 2020. Results: Forty patients (80 eyes) with a diagnosis of BRC were evaluated. The mean age was 53 years, and there was no sex predominance. All tested patients (34/40) were positive for HLA-A29. The diagnosis of BRC was made following the Levinson et al. criteria, and all ancillary tests were performed to exclude diferential diagnoses. Clinical signs and symptoms, such as complications and treatment, were described. Conclusions: BRC evolution in Brazilian patients seems to have some peculiarities that diverge from the published literature available about Caucasians, as AS infammation is higher in this population.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-11-24T19:35:23Z
dc.date.available.fl_str_mv 2023-11-24T19:35:23Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/61364
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.1186/s40942-021-00353-1
dc.identifier.issn.pt_BR.fl_str_mv 2056-9920
url https://doi.org/10.1186/s40942-021-00353-1
http://hdl.handle.net/1843/61364
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dc.publisher.department.fl_str_mv HCL - HOSPITAL DAS CLINICAS
MED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
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