Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | https://doi.org/10.1186/s40942-021-00353-1 http://hdl.handle.net/1843/61364 |
Resumo: | Background: Birdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical fndings and the evolution of BRC in Brazilian patients. Methods: This retrospective cohort multicenter nationwide study was performed by analyzing the records of patients with BRC diagnoses from Brazilian ophthalmological centers from April 1995 to May 2020. Results: Forty patients (80 eyes) with a diagnosis of BRC were evaluated. The mean age was 53 years, and there was no sex predominance. All tested patients (34/40) were positive for HLA-A29. The diagnosis of BRC was made following the Levinson et al. criteria, and all ancillary tests were performed to exclude diferential diagnoses. Clinical signs and symptoms, such as complications and treatment, were described. Conclusions: BRC evolution in Brazilian patients seems to have some peculiarities that diverge from the published literature available about Caucasians, as AS infammation is higher in this population. |
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2023-11-24T19:35:23Z2023-11-24T19:35:23Z20228https://doi.org/10.1186/s40942-021-00353-12056-9920http://hdl.handle.net/1843/61364Background: Birdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical fndings and the evolution of BRC in Brazilian patients. Methods: This retrospective cohort multicenter nationwide study was performed by analyzing the records of patients with BRC diagnoses from Brazilian ophthalmological centers from April 1995 to May 2020. Results: Forty patients (80 eyes) with a diagnosis of BRC were evaluated. The mean age was 53 years, and there was no sex predominance. All tested patients (34/40) were positive for HLA-A29. The diagnosis of BRC was made following the Levinson et al. criteria, and all ancillary tests were performed to exclude diferential diagnoses. Clinical signs and symptoms, such as complications and treatment, were described. Conclusions: BRC evolution in Brazilian patients seems to have some peculiarities that diverge from the published literature available about Caucasians, as AS infammation is higher in this population.Antecedentes: A retinocoroidite de Birdshot (BRC) é uma uveíte bilateral rara e crônica encontrada principalmente em caucasianos. Como poucos dados estão disponíveis sobre a evolução clínica do CBR em pacientes hispânicos, nosso objetivo foi relatar os achados clínicos e a evolução do CBR em pacientes brasileiros. Métodos: Este estudo de coorte retrospectivo multicêntrico de âmbito nacional foi realizado por meio da análise de prontuários de pacientes com diagnóstico de CBR de centros oftalmológicos brasileiros de abril de 1995 a maio de 2020. Resultados: Foram avaliados 40 pacientes (80 olhos) com diagnóstico de CBR. A média de idade foi de 53 anos e não houve predomínio de sexo. Todos os pacientes testados (34/40) foram positivos para HLA-A29. O diagnóstico de BRC foi feito seguindo Levinson et al. critérios, e todos os exames complementares foram realizados para excluir diagnósticos diferenciais. Sinais e sintomas clínicos, como complicações e tratamento, foram descritos. Conclusões: A evolução do CBR em pacientes brasileiros parece apresentar algumas peculiaridades que divergem da literatura publicada disponível sobre caucasianos, uma vez que a inflamação da EA é maior nesta população.engUniversidade Federal de Minas GeraisUFMGBrasilHCL - HOSPITAL DAS CLINICASMED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIAInternational Journal of Retina and VitreousCoriorretinopatia de BirdshotRetinaUveíteBirdshot retinochoroiditisRetinaUveitisBirdshot retinochoroiditis in Brazil: a multicenter study of 40 patientsRetinocoroidite de Birdshot no Brasil: estudo multicêntrico com 40 pacientesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://journalretinavitreous.biomedcentral.com/articles/10.1186/s40942-021-00353-1Maria Luisa Gois da FonsêcaRaul Nunes Galvarro ViannaAnna Christina Higino RochaAntonio Marcelo Barbante CasellaArnaldo CialdiniCristina MucciolliDaniela Socci da CostaDaniel LucenaDaniel Vítor de Vasconcelos SantosEduardo MorizotElaine CastroEver E. C. RodriguezFelipe Telöken DiligentiFernanda B. O. PortoHeloisa NascimentoJoyce Hisae YamamotoJuliana Lambert OréficeLilia R. P. MuralhaLuciana Peixoto FinamorMaria Auxiliadora Monteiro FrazãoMário Martins dos Santos MottaMário J. NóbregaMoysés E. ZajdenweberRemo T. MoraesRodrigo L. MeirellesSidney Rocha LemosWilton Feitosa de Araújoapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/61364/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALBirdshot retinochoroiditis in Brazil_ a multicenter review of 40 patients.pdfBirdshot retinochoroiditis in Brazil_ a multicenter review of 40 patients.pdfapplication/pdf172559https://repositorio.ufmg.br/bitstream/1843/61364/2/Birdshot%20retinochoroiditis%20in%20Brazil_%20a%20multicenter%20review%20of%2040%20patients.pdf41b199f7046396315c7902533f3c105dMD521843/613642023-11-24 16:35:23.469oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-11-24T19:35:23Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.pt_BR.fl_str_mv |
Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients |
dc.title.alternative.pt_BR.fl_str_mv |
Retinocoroidite de Birdshot no Brasil: estudo multicêntrico com 40 pacientes |
title |
Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients |
spellingShingle |
Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients Maria Luisa Gois da Fonsêca Birdshot retinochoroiditis Retina Uveitis Coriorretinopatia de Birdshot Retina Uveíte |
title_short |
Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients |
title_full |
Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients |
title_fullStr |
Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients |
title_full_unstemmed |
Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients |
title_sort |
Birdshot retinochoroiditis in Brazil: a multicenter study of 40 patients |
author |
Maria Luisa Gois da Fonsêca |
author_facet |
Maria Luisa Gois da Fonsêca Raul Nunes Galvarro Vianna Anna Christina Higino Rocha Antonio Marcelo Barbante Casella Arnaldo Cialdini Cristina Mucciolli Daniela Socci da Costa Daniel Lucena Daniel Vítor de Vasconcelos Santos Eduardo Morizot Elaine Castro Ever E. C. Rodriguez Felipe Telöken Diligenti Fernanda B. O. Porto Heloisa Nascimento Joyce Hisae Yamamoto Juliana Lambert Oréfice Lilia R. P. Muralha Luciana Peixoto Finamor Maria Auxiliadora Monteiro Frazão Mário Martins dos Santos Motta Mário J. Nóbrega Moysés E. Zajdenweber Remo T. Moraes Rodrigo L. Meirelles Sidney Rocha Lemos Wilton Feitosa de Araújo |
author_role |
author |
author2 |
Raul Nunes Galvarro Vianna Anna Christina Higino Rocha Antonio Marcelo Barbante Casella Arnaldo Cialdini Cristina Mucciolli Daniela Socci da Costa Daniel Lucena Daniel Vítor de Vasconcelos Santos Eduardo Morizot Elaine Castro Ever E. C. Rodriguez Felipe Telöken Diligenti Fernanda B. O. Porto Heloisa Nascimento Joyce Hisae Yamamoto Juliana Lambert Oréfice Lilia R. P. Muralha Luciana Peixoto Finamor Maria Auxiliadora Monteiro Frazão Mário Martins dos Santos Motta Mário J. Nóbrega Moysés E. Zajdenweber Remo T. Moraes Rodrigo L. Meirelles Sidney Rocha Lemos Wilton Feitosa de Araújo |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Maria Luisa Gois da Fonsêca Raul Nunes Galvarro Vianna Anna Christina Higino Rocha Antonio Marcelo Barbante Casella Arnaldo Cialdini Cristina Mucciolli Daniela Socci da Costa Daniel Lucena Daniel Vítor de Vasconcelos Santos Eduardo Morizot Elaine Castro Ever E. C. Rodriguez Felipe Telöken Diligenti Fernanda B. O. Porto Heloisa Nascimento Joyce Hisae Yamamoto Juliana Lambert Oréfice Lilia R. P. Muralha Luciana Peixoto Finamor Maria Auxiliadora Monteiro Frazão Mário Martins dos Santos Motta Mário J. Nóbrega Moysés E. Zajdenweber Remo T. Moraes Rodrigo L. Meirelles Sidney Rocha Lemos Wilton Feitosa de Araújo |
dc.subject.por.fl_str_mv |
Birdshot retinochoroiditis Retina Uveitis |
topic |
Birdshot retinochoroiditis Retina Uveitis Coriorretinopatia de Birdshot Retina Uveíte |
dc.subject.other.pt_BR.fl_str_mv |
Coriorretinopatia de Birdshot Retina Uveíte |
description |
Background: Birdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical fndings and the evolution of BRC in Brazilian patients. Methods: This retrospective cohort multicenter nationwide study was performed by analyzing the records of patients with BRC diagnoses from Brazilian ophthalmological centers from April 1995 to May 2020. Results: Forty patients (80 eyes) with a diagnosis of BRC were evaluated. The mean age was 53 years, and there was no sex predominance. All tested patients (34/40) were positive for HLA-A29. The diagnosis of BRC was made following the Levinson et al. criteria, and all ancillary tests were performed to exclude diferential diagnoses. Clinical signs and symptoms, such as complications and treatment, were described. Conclusions: BRC evolution in Brazilian patients seems to have some peculiarities that diverge from the published literature available about Caucasians, as AS infammation is higher in this population. |
publishDate |
2022 |
dc.date.issued.fl_str_mv |
2022 |
dc.date.accessioned.fl_str_mv |
2023-11-24T19:35:23Z |
dc.date.available.fl_str_mv |
2023-11-24T19:35:23Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/61364 |
dc.identifier.doi.pt_BR.fl_str_mv |
https://doi.org/10.1186/s40942-021-00353-1 |
dc.identifier.issn.pt_BR.fl_str_mv |
2056-9920 |
url |
https://doi.org/10.1186/s40942-021-00353-1 http://hdl.handle.net/1843/61364 |
identifier_str_mv |
2056-9920 |
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eng |
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eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
International Journal of Retina and Vitreous |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Universidade Federal de Minas Gerais |
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UFMG |
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Brasil |
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HCL - HOSPITAL DAS CLINICAS MED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIA |
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Universidade Federal de Minas Gerais |
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