Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats

Detalhes bibliográficos
Autor(a) principal: Marina Carminatti
Data de Publicação: 2020
Outros Autores: Francine Benetti, Renato Luiz Siqueira, Edgar Dutra Zanotto, André Luiz Fraga Briso, Antônio Hernandes Chaves-Neto, Luciano Tavares Ângelo Cintra
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1590/1678-7757-2019-0384
http://hdl.handle.net/1843/47551
Resumo: CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
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spelling 2022-11-29T21:34:22Z2022-11-29T21:34:22Z2020-06-08280110https://doi.org/10.1590/1678-7757-2019-038416787765http://hdl.handle.net/1843/47551CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPESP - Fundação de Amparo à Pesquisa do Estado de São PauloObjectives This study evaluated if the use of a bioactive glass-ceramic-based gel, named Biosilicate (BS), before, after or mixed with bleaching gel, could influence the inflammation of the dental pulp tissue of rats’ molars undergoing dental bleaching with hydrogen peroxide (H2O2). Methodology The upper molars of Wistar rats (Rattus norvegicus, albinus) were divided into Ble: bleached (35% H2O2, 30-min); Ble-BS: bleached and followed by BS-based gel application (20 min); BS-Ble: BS-based gel application and then bleaching; BS/7d-Ble: BS-based gel applications for 7 days and then bleaching; Ble+BS: blend of H2O2 with BS-based gel (1:1, 30-min); and control: placebo gel. After 2 and 30 days (n=10), the rats were euthanized for histological evaluation. The Kruskal-Wallis and Dunn statistical tests were performed (P<0.05). Results At 2 days, the Ble and Ble-BS groups had significant alterations in the pulp tissue, with an area of necrosis. The groups with the application of BS-based gel before H2O2 had moderate inflammation and partial disorganization in the occlusal third of the coronary pulp and were significantly different from the Ble in the middle and cervical thirds (P<0.05). The most favorable results were observed in the Ble+BS, which was similar to the control in all thirds of the coronary pulp (P>0.05). At 30 days, the pulp tissue was organized and the bleached groups presented tertiary dentin deposition. The Ble group had the highest deposition of tertiary dentin, followed by the Ble-BS, and both were different from control (P<0.05). Conclusion A single BS-based gel application beforehand or BS-based gel blended with a bleaching gel minimize the pulp damage induced by dental bleaching.engUniversidade Federal de Minas GeraisUFMGBrasilFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORAJournal of Applied Oral ScienceDental pulpHydrogen peroxideTooth bleachingTooth remineralizationBioactive glassDental pulpHydrogen peroxideTooth bleaching.Tooth remineralizationExperimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in ratsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.scielo.br/j/jaos/a/rWmYM9cjZDtHyVFpBKNKDyf/?lang=enMarina CarminattiFrancine BenettiRenato Luiz SiqueiraEdgar Dutra ZanottoAndré Luiz Fraga BrisoAntônio Hernandes Chaves-NetoLuciano Tavares Ângelo Cintraapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/47551/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALExperimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats.pdfExperimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats.pdfapplication/pdf3048036https://repositorio.ufmg.br/bitstream/1843/47551/2/Experimental%20gel%20containing%20bioactive%20glass-ceramic%20to%20minimize%20the%20pulp%20damage%20caused%20by%20dental%20bleaching%20in%20rats.pdf57cb44509c2874f63076bac4ffd284a8MD521843/475512022-11-29 18:34:22.59oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2022-11-29T21:34:22Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
title Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
spellingShingle Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
Marina Carminatti
Bioactive glass
Dental pulp
Hydrogen peroxide
Tooth bleaching.
Tooth remineralization
Dental pulp
Hydrogen peroxide
Tooth bleaching
Tooth remineralization
title_short Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
title_full Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
title_fullStr Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
title_full_unstemmed Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
title_sort Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
author Marina Carminatti
author_facet Marina Carminatti
Francine Benetti
Renato Luiz Siqueira
Edgar Dutra Zanotto
André Luiz Fraga Briso
Antônio Hernandes Chaves-Neto
Luciano Tavares Ângelo Cintra
author_role author
author2 Francine Benetti
Renato Luiz Siqueira
Edgar Dutra Zanotto
André Luiz Fraga Briso
Antônio Hernandes Chaves-Neto
Luciano Tavares Ângelo Cintra
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Marina Carminatti
Francine Benetti
Renato Luiz Siqueira
Edgar Dutra Zanotto
André Luiz Fraga Briso
Antônio Hernandes Chaves-Neto
Luciano Tavares Ângelo Cintra
dc.subject.por.fl_str_mv Bioactive glass
Dental pulp
Hydrogen peroxide
Tooth bleaching.
Tooth remineralization
topic Bioactive glass
Dental pulp
Hydrogen peroxide
Tooth bleaching.
Tooth remineralization
Dental pulp
Hydrogen peroxide
Tooth bleaching
Tooth remineralization
dc.subject.other.pt_BR.fl_str_mv Dental pulp
Hydrogen peroxide
Tooth bleaching
Tooth remineralization
description CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
publishDate 2020
dc.date.issued.fl_str_mv 2020-06-08
dc.date.accessioned.fl_str_mv 2022-11-29T21:34:22Z
dc.date.available.fl_str_mv 2022-11-29T21:34:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/47551
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.1590/1678-7757-2019-0384
dc.identifier.issn.pt_BR.fl_str_mv 16787765
url https://doi.org/10.1590/1678-7757-2019-0384
http://hdl.handle.net/1843/47551
identifier_str_mv 16787765
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Journal of Applied Oral Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv FAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
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