Pediatric lupus nephritis

Detalhes bibliográficos
Autor(a) principal: Sérgio Veloso Brant Pinheiro
Data de Publicação: 2019
Outros Autores: Raphael Figuiredo Dias, Rafaela Cabral Gonçalves Fabiano, Stanley de Almeida Araujo, Ana Cristina Simões e Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://hdl.handle.net/1843/60792
Resumo: Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options.
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spelling 2023-11-10T20:09:27Z2023-11-10T20:09:27Z201941225226510.1590/2175-8239-jbn-2018-009721758239http://hdl.handle.net/1843/60792Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options.A nefrite lúpica (NL) é caracterizada pelo acometimento dos rins no contexto das diversas manifestações clínicas do Lupus Eritematoso Sistêmico (LES), e representa uma das manifestações clínicas mais graves da doença. A NL é mais frequente e mais grave nos pacientes pediátricos, em comparação com os adultos, e causa maiores taxas de morbidade e mortalidade. O objetivo desta revisão narrativa foi descrever os aspectos gerais da NL e suas particularidades em crianças e adolescentes, com foco em sua etiopatogênese, nas manifestações clínicas, nas alterações histopatológicas renais e na abordagem terapêutica.engUniversidade Federal de Minas GeraisUFMGBrasilMED - DEPARTAMENTO DE PEDIATRIABrazilian Journal of NephrologyLupus nephritisLupus Erythematosus, SystemicAutoimmunityAntibodies, AntinuclearLupus nephritisSystemic Lupus ErythematosusAutoimmunityAntibodies, AntinuclearPediatric lupus nephritisNefrite lúpica em pediatriainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.1590/2175-8239-JBN-2018-0097Sérgio Veloso Brant PinheiroRaphael Figuiredo DiasRafaela Cabral Gonçalves FabianoStanley de Almeida AraujoAna Cristina Simões e Silvaapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/60792/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALPediatric lupus nephritis pdfa.pdfPediatric lupus nephritis pdfa.pdfapplication/pdf22338286https://repositorio.ufmg.br/bitstream/1843/60792/2/Pediatric%20lupus%20nephritis%20pdfa.pdfe7cced29d71d07f188591a4b45532781MD521843/607922023-11-10 17:36:38.109oai:repositorio.ufmg.br:1843/60792Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-11-10T20:36:38Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Pediatric lupus nephritis
dc.title.alternative.pt_BR.fl_str_mv Nefrite lúpica em pediatria
title Pediatric lupus nephritis
spellingShingle Pediatric lupus nephritis
Sérgio Veloso Brant Pinheiro
Lupus nephritis
Systemic Lupus Erythematosus
Autoimmunity
Antibodies, Antinuclear
Lupus nephritis
Lupus Erythematosus, Systemic
Autoimmunity
Antibodies, Antinuclear
title_short Pediatric lupus nephritis
title_full Pediatric lupus nephritis
title_fullStr Pediatric lupus nephritis
title_full_unstemmed Pediatric lupus nephritis
title_sort Pediatric lupus nephritis
author Sérgio Veloso Brant Pinheiro
author_facet Sérgio Veloso Brant Pinheiro
Raphael Figuiredo Dias
Rafaela Cabral Gonçalves Fabiano
Stanley de Almeida Araujo
Ana Cristina Simões e Silva
author_role author
author2 Raphael Figuiredo Dias
Rafaela Cabral Gonçalves Fabiano
Stanley de Almeida Araujo
Ana Cristina Simões e Silva
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Sérgio Veloso Brant Pinheiro
Raphael Figuiredo Dias
Rafaela Cabral Gonçalves Fabiano
Stanley de Almeida Araujo
Ana Cristina Simões e Silva
dc.subject.por.fl_str_mv Lupus nephritis
Systemic Lupus Erythematosus
Autoimmunity
Antibodies, Antinuclear
topic Lupus nephritis
Systemic Lupus Erythematosus
Autoimmunity
Antibodies, Antinuclear
Lupus nephritis
Lupus Erythematosus, Systemic
Autoimmunity
Antibodies, Antinuclear
dc.subject.other.pt_BR.fl_str_mv Lupus nephritis
Lupus Erythematosus, Systemic
Autoimmunity
Antibodies, Antinuclear
description Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options.
publishDate 2019
dc.date.issued.fl_str_mv 2019
dc.date.accessioned.fl_str_mv 2023-11-10T20:09:27Z
dc.date.available.fl_str_mv 2023-11-10T20:09:27Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/60792
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/2175-8239-jbn-2018-0097
dc.identifier.issn.pt_BR.fl_str_mv 21758239
identifier_str_mv 10.1590/2175-8239-jbn-2018-0097
21758239
url http://hdl.handle.net/1843/60792
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Brazilian Journal of Nephrology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv MED - DEPARTAMENTO DE PEDIATRIA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
bitstream.url.fl_str_mv https://repositorio.ufmg.br/bitstream/1843/60792/1/License.txt
https://repositorio.ufmg.br/bitstream/1843/60792/2/Pediatric%20lupus%20nephritis%20pdfa.pdf
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