Pediatric lupus nephritis
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | http://hdl.handle.net/1843/60792 |
Resumo: | Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options. |
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2023-11-10T20:09:27Z2023-11-10T20:09:27Z201941225226510.1590/2175-8239-jbn-2018-009721758239http://hdl.handle.net/1843/60792Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options.A nefrite lúpica (NL) é caracterizada pelo acometimento dos rins no contexto das diversas manifestações clínicas do Lupus Eritematoso Sistêmico (LES), e representa uma das manifestações clínicas mais graves da doença. A NL é mais frequente e mais grave nos pacientes pediátricos, em comparação com os adultos, e causa maiores taxas de morbidade e mortalidade. O objetivo desta revisão narrativa foi descrever os aspectos gerais da NL e suas particularidades em crianças e adolescentes, com foco em sua etiopatogênese, nas manifestações clínicas, nas alterações histopatológicas renais e na abordagem terapêutica.engUniversidade Federal de Minas GeraisUFMGBrasilMED - DEPARTAMENTO DE PEDIATRIABrazilian Journal of NephrologyLupus nephritisLupus Erythematosus, SystemicAutoimmunityAntibodies, AntinuclearLupus nephritisSystemic Lupus ErythematosusAutoimmunityAntibodies, AntinuclearPediatric lupus nephritisNefrite lúpica em pediatriainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.1590/2175-8239-JBN-2018-0097Sérgio Veloso Brant PinheiroRaphael Figuiredo DiasRafaela Cabral Gonçalves FabianoStanley de Almeida AraujoAna Cristina Simões e Silvaapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/60792/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALPediatric lupus nephritis pdfa.pdfPediatric lupus nephritis pdfa.pdfapplication/pdf22338286https://repositorio.ufmg.br/bitstream/1843/60792/2/Pediatric%20lupus%20nephritis%20pdfa.pdfe7cced29d71d07f188591a4b45532781MD521843/607922023-11-10 17:36:38.109oai:repositorio.ufmg.br:1843/60792Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-11-10T20:36:38Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.pt_BR.fl_str_mv |
Pediatric lupus nephritis |
dc.title.alternative.pt_BR.fl_str_mv |
Nefrite lúpica em pediatria |
title |
Pediatric lupus nephritis |
spellingShingle |
Pediatric lupus nephritis Sérgio Veloso Brant Pinheiro Lupus nephritis Systemic Lupus Erythematosus Autoimmunity Antibodies, Antinuclear Lupus nephritis Lupus Erythematosus, Systemic Autoimmunity Antibodies, Antinuclear |
title_short |
Pediatric lupus nephritis |
title_full |
Pediatric lupus nephritis |
title_fullStr |
Pediatric lupus nephritis |
title_full_unstemmed |
Pediatric lupus nephritis |
title_sort |
Pediatric lupus nephritis |
author |
Sérgio Veloso Brant Pinheiro |
author_facet |
Sérgio Veloso Brant Pinheiro Raphael Figuiredo Dias Rafaela Cabral Gonçalves Fabiano Stanley de Almeida Araujo Ana Cristina Simões e Silva |
author_role |
author |
author2 |
Raphael Figuiredo Dias Rafaela Cabral Gonçalves Fabiano Stanley de Almeida Araujo Ana Cristina Simões e Silva |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Sérgio Veloso Brant Pinheiro Raphael Figuiredo Dias Rafaela Cabral Gonçalves Fabiano Stanley de Almeida Araujo Ana Cristina Simões e Silva |
dc.subject.por.fl_str_mv |
Lupus nephritis Systemic Lupus Erythematosus Autoimmunity Antibodies, Antinuclear |
topic |
Lupus nephritis Systemic Lupus Erythematosus Autoimmunity Antibodies, Antinuclear Lupus nephritis Lupus Erythematosus, Systemic Autoimmunity Antibodies, Antinuclear |
dc.subject.other.pt_BR.fl_str_mv |
Lupus nephritis Lupus Erythematosus, Systemic Autoimmunity Antibodies, Antinuclear |
description |
Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options. |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019 |
dc.date.accessioned.fl_str_mv |
2023-11-10T20:09:27Z |
dc.date.available.fl_str_mv |
2023-11-10T20:09:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/60792 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.1590/2175-8239-jbn-2018-0097 |
dc.identifier.issn.pt_BR.fl_str_mv |
21758239 |
identifier_str_mv |
10.1590/2175-8239-jbn-2018-0097 21758239 |
url |
http://hdl.handle.net/1843/60792 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Brazilian Journal of Nephrology |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
dc.publisher.initials.fl_str_mv |
UFMG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
MED - DEPARTAMENTO DE PEDIATRIA |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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UFMG |
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UFMG |
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Repositório Institucional da UFMG |
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Repositório Institucional da UFMG |
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