Chemical composition and evaluation of antibacterial and antioxidant activities of the essential oil of Croton urucurana Baillon (Euphorbiaceae) stem bark

• Autor(a) principal: Simionatto, Euclésio
• Data de Publicação: 2007
• Outros Autores: Bonani, Vanderléa F. L., Morel, Ademir Farias, Poppi, Nilva Ré, Raposo Júnior, Jorge Luiz, Stuker, Caroline Z., Peruzzo, Gisele M., Peres, Marize Terezinha Lopes Pereira, Hess, Sônia Corina
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMS
• DOI: 10.1590/S0103-50532007000500002
• Texto Completo: https://repositorio.ufms.br/handle/123456789/166
• topic: Óleo de Croton; Plantas Medicinais; Antioxidantes; Produtos com Ação Antimicrobiana; Croton Oil; Plants, Medicinal; Antioxidants; Products with Antimicrobial Action

The essential oil obtained from the stem bark of Croton urucurana Baillon (Euphorbiaceae) was analysed by GC and GC-MS. 83 compounds were identified and borneol (14.7%), bornyl acetate (5.2%), 1-isopropyl-7-methyl-4-methylene-1,3,4,5,6,8-hexahydro-2H-naphthalen-4a-ol (14.7%), sesquicineole (10.5%) and g-gurjunene epoxide (5.4%) were the main components. The EC50 value of the crude essential oil in the DPPH free radical scavenging assay was 3.21 mg mL-1. The fraction of the crude essential oil that presented antioxidant activity was purified by prep-TLC on silica gel. GC and GC-MS analysis revealed that a-bisabolol (38.3%), a-eudesmol (9.3%) and guaiol (8.2%) were the main components of the antioxidant fraction. The EC50 value measured for the bioactive oil fraction in the DPPH assay was 1.05 mg mL-1. The antimicrobial activity of the crude essential oil was assayed against seven Gram-positive and Gram-negative bacteria and three yeasts. Measured MIC values ranged from 1.25 to 10.00 mg mL-1.