Circulação de herpesvírus na comunidade indígena Haliti-Paresí

Detalhes bibliográficos
Autor(a) principal: Rossi, Elaine Menezes
Data de Publicação: 2022
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFMT
Texto Completo: http://ri.ufmt.br/handle/1/5948
Resumo: Introduction - Infections caused by human herpesvirus are considered the most frequent sexually transmitted infection in the world, with a wide spectrum of clinical involvement, acute and reactive infections, high transmissibility and even orofacial and anogenital lesions caused by human Alphaherpesvirus 1 (HSV) and 2 (HSV-2), respectively. In the case of indigenous populations, herpetic infections further aggravate the health situation of this population, given that they have some of the worst social indicators in the country, in addition to inequity in access to health services and increased vulnerabilities. Objective - Thus, we sought to investigate the seroprevalence of HSV-1 and HSV-2 infection in Haliti-Paresí indigenous people in Mato Grosso, Brazil. Methods - Its development was based on cross-sectional research. Data collection was carried out in 2015, in nine villages of the Haliti-Paresí ethnic group, located in the municipality of Campo Novo do Parecis, Mato Grosso. Questionnaires were applied to collect sociodemographic data, with subsequent collection of peripheral blood for the constitution of the Biobank. The variables investigated were reactivation by herpes type 1 and herpes type 2 and sociodemographic variables: sex, age group, schooling, family income, number of residents in the household, carrying out activities outside the village, number of sexual partners, condom use and manifestations. clinical symptoms in the last thirty days, such as: fever, headache, myalgia, dizziness, low back pain, diarrhea, nausea, oral and/or genital lesions and abdominal pain. Bivariate analysis, Likelihood Ratio Test and Fisher's Exact Test were used, with significant Chisquare at 5%. Sample analysis was performed in May 2020, at the Viral Immunology laboratory of Instituto Oswaldo Cruz, using an enzyme-linked immunosorbent assay (ELISA) to determine Immunoglobulin G (IgG) in herpes types 1 and 2. Results - 100 indigenous people participated in the study, with a prevalence of females (60%), adults aged between 18 and 59 years (61%), low schooling (67%) and monthly income of 1 to 2 minimum wages (83%). Most respondents claimed not to carry out activities outside the village (79%), reported having only one sexual partner (73%) and did not have the habit of using condoms during sexual intercourse (70%). Among the interviewees, 97% were seropositive for herpes type 1 and 24% for type 2. In the analysis of clinical aspects, there was a statistically significant association between self-reported autogenital lesion and clinical manifestations fever (p<0.01), myalgia (p=0.01), oral lesion (p=0.01) and reactivation by herpes type 1 and type 2 (p=0.039). Conclusion - In view of this, the high seroprevalence of herpesvirus in this ethnic group, associated with several symptoms, indicates the urgency of actions aimed at preventing and controlling the spread of human herpesviruses, taking into account socio-cultural aspects of this population.
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spelling Circulação de herpesvírus na comunidade indígena Haliti-ParesíHerpes simplesSaúde públicaSaúde de populações indígenasVulnerabilidade em saúdeCNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVAHerpes simplexPublic healthHealth of indigenous peoplesHealth vulnerabilityIntroduction - Infections caused by human herpesvirus are considered the most frequent sexually transmitted infection in the world, with a wide spectrum of clinical involvement, acute and reactive infections, high transmissibility and even orofacial and anogenital lesions caused by human Alphaherpesvirus 1 (HSV) and 2 (HSV-2), respectively. In the case of indigenous populations, herpetic infections further aggravate the health situation of this population, given that they have some of the worst social indicators in the country, in addition to inequity in access to health services and increased vulnerabilities. Objective - Thus, we sought to investigate the seroprevalence of HSV-1 and HSV-2 infection in Haliti-Paresí indigenous people in Mato Grosso, Brazil. Methods - Its development was based on cross-sectional research. Data collection was carried out in 2015, in nine villages of the Haliti-Paresí ethnic group, located in the municipality of Campo Novo do Parecis, Mato Grosso. Questionnaires were applied to collect sociodemographic data, with subsequent collection of peripheral blood for the constitution of the Biobank. The variables investigated were reactivation by herpes type 1 and herpes type 2 and sociodemographic variables: sex, age group, schooling, family income, number of residents in the household, carrying out activities outside the village, number of sexual partners, condom use and manifestations. clinical symptoms in the last thirty days, such as: fever, headache, myalgia, dizziness, low back pain, diarrhea, nausea, oral and/or genital lesions and abdominal pain. Bivariate analysis, Likelihood Ratio Test and Fisher's Exact Test were used, with significant Chisquare at 5%. Sample analysis was performed in May 2020, at the Viral Immunology laboratory of Instituto Oswaldo Cruz, using an enzyme-linked immunosorbent assay (ELISA) to determine Immunoglobulin G (IgG) in herpes types 1 and 2. Results - 100 indigenous people participated in the study, with a prevalence of females (60%), adults aged between 18 and 59 years (61%), low schooling (67%) and monthly income of 1 to 2 minimum wages (83%). Most respondents claimed not to carry out activities outside the village (79%), reported having only one sexual partner (73%) and did not have the habit of using condoms during sexual intercourse (70%). Among the interviewees, 97% were seropositive for herpes type 1 and 24% for type 2. In the analysis of clinical aspects, there was a statistically significant association between self-reported autogenital lesion and clinical manifestations fever (p<0.01), myalgia (p=0.01), oral lesion (p=0.01) and reactivation by herpes type 1 and type 2 (p=0.039). Conclusion - In view of this, the high seroprevalence of herpesvirus in this ethnic group, associated with several symptoms, indicates the urgency of actions aimed at preventing and controlling the spread of human herpesviruses, taking into account socio-cultural aspects of this population.CAPESIntrodução - As infecções provocadas pelo herpesvírus humano são consideradas como a infecção sexualmente transmissível mais frequente no mundo, com um amplo espectro de acometimentos clínicos, infecções agudas e reativas, alta transmissibilidade e, ainda lesões orofacial e anogenital, provocadas pelo Alphaherpesvírus humano 1 (HSV-1) e 2 (HSV-2), respectivamente. Em se tratando de populações indígenas, as infecções herpéticas agravam ainda mais a situação de saúde desta população, tendo em vista que estes apresentam alguns dos piores indicadores sociais do país, somados a iniquidade no acesso aos serviços de saúde e aumento das vulnerabilidades. Objetivo - Assim, buscou-se investigar a soroprevalência da infecção por HSV-1 e HSV-2em indígenas da etnia Haliti-Paresí no Mato Grosso, Brasil. Métodos - O seu desenvolvimento se deu a partir de pesquisa de caráter transversal. A coleta de dados foi realizada no ano de 2015, em nove aldeias da etnia Haliti-Paresí, situadas no município Campo Novo do Parecis, Mato Grosso. Aplicou-se questionários para coleta dos dados sociodemográficos, com posterior coleta de sangue periférico para constituição do Biobanco. As variáveis investigadas foram reativações por herpes tipo 1 e herpes tipo 2 e variáveis sociodemográficas: sexo, faixa etária, escolaridade, renda familiar, quantidade de moradores no domicílio, realização de atividades fora da aldeia, número de parceiros sexuais, uso de preservativo e manifestações clínicas nos últimos trinta dias, como: febre, cefaleia, mialgia, tontura, dor lombar, diarreia, náuseas, lesão oral e/ou na região genital e dor abdominal. Empregou-se análise bivariada, Teste da Razão de Verossimilhança e Teste Exato de Fischer, com Qui-quadrado significativo ao nível de 5%. A análise das amostras foi realizada em maio de 2020, no laboratório de Imunologia Viral do Instituto Oswaldo Cruz, com o uso de ensaio de imunoabsorção enzimática (ELISA) para determinação da Imunoglobulina G (IgG), de herpes tipo 1 e 2. Resultados - Participaram do estudo 100 indígenas, com prevalência do sexo feminino (60%), adultos com idade entre 18 e 59 anos (61%), baixa escolaridade (67%) e renda mensal de 1 a 2 salários mínimos (83%). A maioria dos entrevistados alegaram não realizar atividades fora da aldeia (79%), relataram possuir apenas um parceiro sexual (73%) e não possuíam o hábito de usar preservativo durante as relações sexuais (70%). Dentre os entrevistados, 97% eram soropositivos para herpes tipo 1 e 24% para o tipo 2. Na análise dos aspectos clínicos, houve associação estatisticamente significativa entre lesão auto genital autorreferida e as manifestações clínicas febre (p<0,01), mialgia (p=0,01), lesão oral (p=0,01) e reativação por herpes tipo 1 e tipo 2 (p=0,039). Conclusão - Diante disso, a alta soroprevalência de herpesvírus nesta etnia, associados a diversos sintomas, indica a urgência em ações que visem prevenir e controlar a disseminação dos herpesvírus humano, levando em consideração aspectos sócio culturais desta população.Universidade Federal de Mato GrossoBrasilInstituto de Saúde Coletiva (ISC)UFMT CUC - CuiabáPrograma de Pós-Graduação em Saúde ColetivaTrettel, Ana Cláudia Pereira TerçasEspinosa, Mariano Martinezhttp://lattes.cnpq.br/9561670286584410http://lattes.cnpq.br/9144280121462086Trettel, Ana Claudia Pereira Terças704.996.401-87http://lattes.cnpq.br/9144280121462086Muraro, Ana Paula003.957.481-43http://lattes.cnpq.br/1256112467400959704.996.401-87132.155.378-18Rodrigues, Luana Lorena Silva866.070.902-06http://lattes.cnpq.br/5536252180803475Rossi, Elaine Menezes2024-09-16T15:52:15Z2022-10-262024-09-16T15:52:15Z2022-09-26info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisROSSI, Elaine Menezes. Circulação de herpesvírus na comunidade indígena Haliti-Paresí. 2022. 64 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2022.http://ri.ufmt.br/handle/1/5948porinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMTinstname:Universidade Federal de Mato Grosso (UFMT)instacron:UFMT2024-09-17T07:02:05Zoai:localhost:1/5948Repositório InstitucionalPUBhttp://ri.ufmt.br/oai/requestjordanbiblio@gmail.comopendoar:2024-09-17T07:02:05Repositório Institucional da UFMT - Universidade Federal de Mato Grosso (UFMT)false
dc.title.none.fl_str_mv Circulação de herpesvírus na comunidade indígena Haliti-Paresí
title Circulação de herpesvírus na comunidade indígena Haliti-Paresí
spellingShingle Circulação de herpesvírus na comunidade indígena Haliti-Paresí
Rossi, Elaine Menezes
Herpes simples
Saúde pública
Saúde de populações indígenas
Vulnerabilidade em saúde
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Herpes simplex
Public health
Health of indigenous peoples
Health vulnerability
title_short Circulação de herpesvírus na comunidade indígena Haliti-Paresí
title_full Circulação de herpesvírus na comunidade indígena Haliti-Paresí
title_fullStr Circulação de herpesvírus na comunidade indígena Haliti-Paresí
title_full_unstemmed Circulação de herpesvírus na comunidade indígena Haliti-Paresí
title_sort Circulação de herpesvírus na comunidade indígena Haliti-Paresí
author Rossi, Elaine Menezes
author_facet Rossi, Elaine Menezes
author_role author
dc.contributor.none.fl_str_mv Trettel, Ana Cláudia Pereira Terças
Espinosa, Mariano Martinez
http://lattes.cnpq.br/9561670286584410
http://lattes.cnpq.br/9144280121462086
Trettel, Ana Claudia Pereira Terças
704.996.401-87
http://lattes.cnpq.br/9144280121462086
Muraro, Ana Paula
003.957.481-43
http://lattes.cnpq.br/1256112467400959
704.996.401-87
132.155.378-18
Rodrigues, Luana Lorena Silva
866.070.902-06
http://lattes.cnpq.br/5536252180803475
dc.contributor.author.fl_str_mv Rossi, Elaine Menezes
dc.subject.por.fl_str_mv Herpes simples
Saúde pública
Saúde de populações indígenas
Vulnerabilidade em saúde
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Herpes simplex
Public health
Health of indigenous peoples
Health vulnerability
topic Herpes simples
Saúde pública
Saúde de populações indígenas
Vulnerabilidade em saúde
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Herpes simplex
Public health
Health of indigenous peoples
Health vulnerability
description Introduction - Infections caused by human herpesvirus are considered the most frequent sexually transmitted infection in the world, with a wide spectrum of clinical involvement, acute and reactive infections, high transmissibility and even orofacial and anogenital lesions caused by human Alphaherpesvirus 1 (HSV) and 2 (HSV-2), respectively. In the case of indigenous populations, herpetic infections further aggravate the health situation of this population, given that they have some of the worst social indicators in the country, in addition to inequity in access to health services and increased vulnerabilities. Objective - Thus, we sought to investigate the seroprevalence of HSV-1 and HSV-2 infection in Haliti-Paresí indigenous people in Mato Grosso, Brazil. Methods - Its development was based on cross-sectional research. Data collection was carried out in 2015, in nine villages of the Haliti-Paresí ethnic group, located in the municipality of Campo Novo do Parecis, Mato Grosso. Questionnaires were applied to collect sociodemographic data, with subsequent collection of peripheral blood for the constitution of the Biobank. The variables investigated were reactivation by herpes type 1 and herpes type 2 and sociodemographic variables: sex, age group, schooling, family income, number of residents in the household, carrying out activities outside the village, number of sexual partners, condom use and manifestations. clinical symptoms in the last thirty days, such as: fever, headache, myalgia, dizziness, low back pain, diarrhea, nausea, oral and/or genital lesions and abdominal pain. Bivariate analysis, Likelihood Ratio Test and Fisher's Exact Test were used, with significant Chisquare at 5%. Sample analysis was performed in May 2020, at the Viral Immunology laboratory of Instituto Oswaldo Cruz, using an enzyme-linked immunosorbent assay (ELISA) to determine Immunoglobulin G (IgG) in herpes types 1 and 2. Results - 100 indigenous people participated in the study, with a prevalence of females (60%), adults aged between 18 and 59 years (61%), low schooling (67%) and monthly income of 1 to 2 minimum wages (83%). Most respondents claimed not to carry out activities outside the village (79%), reported having only one sexual partner (73%) and did not have the habit of using condoms during sexual intercourse (70%). Among the interviewees, 97% were seropositive for herpes type 1 and 24% for type 2. In the analysis of clinical aspects, there was a statistically significant association between self-reported autogenital lesion and clinical manifestations fever (p<0.01), myalgia (p=0.01), oral lesion (p=0.01) and reactivation by herpes type 1 and type 2 (p=0.039). Conclusion - In view of this, the high seroprevalence of herpesvirus in this ethnic group, associated with several symptoms, indicates the urgency of actions aimed at preventing and controlling the spread of human herpesviruses, taking into account socio-cultural aspects of this population.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-26
2022-09-26
2024-09-16T15:52:15Z
2024-09-16T15:52:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv ROSSI, Elaine Menezes. Circulação de herpesvírus na comunidade indígena Haliti-Paresí. 2022. 64 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2022.
http://ri.ufmt.br/handle/1/5948
identifier_str_mv ROSSI, Elaine Menezes. Circulação de herpesvírus na comunidade indígena Haliti-Paresí. 2022. 64 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2022.
url http://ri.ufmt.br/handle/1/5948
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Mato Grosso
Brasil
Instituto de Saúde Coletiva (ISC)
UFMT CUC - Cuiabá
Programa de Pós-Graduação em Saúde Coletiva
publisher.none.fl_str_mv Universidade Federal de Mato Grosso
Brasil
Instituto de Saúde Coletiva (ISC)
UFMT CUC - Cuiabá
Programa de Pós-Graduação em Saúde Coletiva
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMT
instname:Universidade Federal de Mato Grosso (UFMT)
instacron:UFMT
instname_str Universidade Federal de Mato Grosso (UFMT)
instacron_str UFMT
institution UFMT
reponame_str Repositório Institucional da UFMT
collection Repositório Institucional da UFMT
repository.name.fl_str_mv Repositório Institucional da UFMT - Universidade Federal de Mato Grosso (UFMT)
repository.mail.fl_str_mv jordanbiblio@gmail.com
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