Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.

Detalhes bibliográficos
Autor(a) principal: Miranda, Denise Coutinho de
Data de Publicação: 2021
Outros Autores: Lavorato, Victor Neiva, Carneiro Júnior, Miguel Araújo, Paula, Ana Beatriz Rezende, Silva, Karina Ana, Drummond, Filipe Rios, Silva, Marcelo Eustáquio, Cabral, Carlos Augusto Costa, Isoldi, Mauro César, Natali, Antônio José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFOP
Texto Completo: http://www.repositorio.ufop.br/jspui/handle/123456789/16514
https://doi.org/10.1590/1678-4324-2021210085
Resumo: The present study investigated the effects of aerobic physical training on the femoral morphological, densitometric and biomechanical properties in growing male rats subjected to protein-based malnutrition. Four-week-old male Wistar rats were randomized into groups of 10 animals: Control Sedentary (CS), Control Trained (CT), Malnourished Sedentary (MS) and Malnourished Trained (MT). Control and malnourished animals received diets with 12% protein and 6% protein, respectively. The trained groups were submitted to a treadmill running program for 8 weeks. Total proteins and albumin were analyzed in the animals' blood plasma. Histological, densitometric and biomechanical analyzes were performed on the animals' femur. Body mass gain, physical performance, biochemical markers and the femoral morphological, densitometric and biomechanical properties were determined. Exercise tolerance increased in trained groups. Malnourished animals exhibited lower serum protein and albumin levels than controls. Porosity and trabecular bone density were not different between groups. The femoral maximum load, maximum load until fracture, resilience, stiffness, tenacity and densitometric properties were reduced by malnutrition. Physical training associated with malnutrition exacerbated the impairment in the femoral maximum load, maximum load until fracture, bone mineral content and density. Aerobic physical training worsens the damages induced by protein-based malnutrition in the femoral biomechanical and densitometric properties of growing male rats.
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spelling Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.Aerobic exerciseBone mineral densityProtein malnutritionTrabecular boneFractureThe present study investigated the effects of aerobic physical training on the femoral morphological, densitometric and biomechanical properties in growing male rats subjected to protein-based malnutrition. Four-week-old male Wistar rats were randomized into groups of 10 animals: Control Sedentary (CS), Control Trained (CT), Malnourished Sedentary (MS) and Malnourished Trained (MT). Control and malnourished animals received diets with 12% protein and 6% protein, respectively. The trained groups were submitted to a treadmill running program for 8 weeks. Total proteins and albumin were analyzed in the animals' blood plasma. Histological, densitometric and biomechanical analyzes were performed on the animals' femur. Body mass gain, physical performance, biochemical markers and the femoral morphological, densitometric and biomechanical properties were determined. Exercise tolerance increased in trained groups. Malnourished animals exhibited lower serum protein and albumin levels than controls. Porosity and trabecular bone density were not different between groups. The femoral maximum load, maximum load until fracture, resilience, stiffness, tenacity and densitometric properties were reduced by malnutrition. Physical training associated with malnutrition exacerbated the impairment in the femoral maximum load, maximum load until fracture, bone mineral content and density. Aerobic physical training worsens the damages induced by protein-based malnutrition in the femoral biomechanical and densitometric properties of growing male rats.2023-05-03T21:00:52Z2023-05-03T21:00:52Z2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfMIRANDA, D. C. de et al. Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition. Brazilian Archives of Biology and Technology, v. 64, artigo e21210085, 2021. Disponível em: <https://www.scielo.br/j/babt/a/GGLGRdLg9jvXs67spnqZQHN/>. Acesso em: 11 out. 2022.1678-4324http://www.repositorio.ufop.br/jspui/handle/123456789/16514https://doi.org/10.1590/1678-4324-2021210085Submitted for possible open access publication under the terms and conditions of the Creative Commons Attribution (CC BY NC) license (https://creativecommons.org/licenses/by-nc/4.0/). Fonte: o PDF do artigo.info:eu-repo/semantics/openAccessMiranda, Denise Coutinho deLavorato, Victor NeivaCarneiro Júnior, Miguel AraújoPaula, Ana Beatriz RezendeSilva, Karina AnaDrummond, Filipe RiosSilva, Marcelo EustáquioCabral, Carlos Augusto CostaIsoldi, Mauro CésarNatali, Antônio Joséengreponame:Repositório Institucional da UFOPinstname:Universidade Federal de Ouro Preto (UFOP)instacron:UFOP2023-05-03T21:01:01Zoai:repositorio.ufop.br:123456789/16514Repositório InstitucionalPUBhttp://www.repositorio.ufop.br/oai/requestrepositorio@ufop.edu.bropendoar:32332023-05-03T21:01:01Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)false
dc.title.none.fl_str_mv Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.
title Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.
spellingShingle Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.
Miranda, Denise Coutinho de
Aerobic exercise
Bone mineral density
Protein malnutrition
Trabecular bone
Fracture
title_short Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.
title_full Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.
title_fullStr Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.
title_full_unstemmed Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.
title_sort Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition.
author Miranda, Denise Coutinho de
author_facet Miranda, Denise Coutinho de
Lavorato, Victor Neiva
Carneiro Júnior, Miguel Araújo
Paula, Ana Beatriz Rezende
Silva, Karina Ana
Drummond, Filipe Rios
Silva, Marcelo Eustáquio
Cabral, Carlos Augusto Costa
Isoldi, Mauro César
Natali, Antônio José
author_role author
author2 Lavorato, Victor Neiva
Carneiro Júnior, Miguel Araújo
Paula, Ana Beatriz Rezende
Silva, Karina Ana
Drummond, Filipe Rios
Silva, Marcelo Eustáquio
Cabral, Carlos Augusto Costa
Isoldi, Mauro César
Natali, Antônio José
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Miranda, Denise Coutinho de
Lavorato, Victor Neiva
Carneiro Júnior, Miguel Araújo
Paula, Ana Beatriz Rezende
Silva, Karina Ana
Drummond, Filipe Rios
Silva, Marcelo Eustáquio
Cabral, Carlos Augusto Costa
Isoldi, Mauro César
Natali, Antônio José
dc.subject.por.fl_str_mv Aerobic exercise
Bone mineral density
Protein malnutrition
Trabecular bone
Fracture
topic Aerobic exercise
Bone mineral density
Protein malnutrition
Trabecular bone
Fracture
description The present study investigated the effects of aerobic physical training on the femoral morphological, densitometric and biomechanical properties in growing male rats subjected to protein-based malnutrition. Four-week-old male Wistar rats were randomized into groups of 10 animals: Control Sedentary (CS), Control Trained (CT), Malnourished Sedentary (MS) and Malnourished Trained (MT). Control and malnourished animals received diets with 12% protein and 6% protein, respectively. The trained groups were submitted to a treadmill running program for 8 weeks. Total proteins and albumin were analyzed in the animals' blood plasma. Histological, densitometric and biomechanical analyzes were performed on the animals' femur. Body mass gain, physical performance, biochemical markers and the femoral morphological, densitometric and biomechanical properties were determined. Exercise tolerance increased in trained groups. Malnourished animals exhibited lower serum protein and albumin levels than controls. Porosity and trabecular bone density were not different between groups. The femoral maximum load, maximum load until fracture, resilience, stiffness, tenacity and densitometric properties were reduced by malnutrition. Physical training associated with malnutrition exacerbated the impairment in the femoral maximum load, maximum load until fracture, bone mineral content and density. Aerobic physical training worsens the damages induced by protein-based malnutrition in the femoral biomechanical and densitometric properties of growing male rats.
publishDate 2021
dc.date.none.fl_str_mv 2021
2023-05-03T21:00:52Z
2023-05-03T21:00:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv MIRANDA, D. C. de et al. Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition. Brazilian Archives of Biology and Technology, v. 64, artigo e21210085, 2021. Disponível em: <https://www.scielo.br/j/babt/a/GGLGRdLg9jvXs67spnqZQHN/>. Acesso em: 11 out. 2022.
1678-4324
http://www.repositorio.ufop.br/jspui/handle/123456789/16514
https://doi.org/10.1590/1678-4324-2021210085
identifier_str_mv MIRANDA, D. C. de et al. Aerobic exercise increases the damage to the femoral properties of growing rats with protein-based malnutrition. Brazilian Archives of Biology and Technology, v. 64, artigo e21210085, 2021. Disponível em: <https://www.scielo.br/j/babt/a/GGLGRdLg9jvXs67spnqZQHN/>. Acesso em: 11 out. 2022.
1678-4324
url http://www.repositorio.ufop.br/jspui/handle/123456789/16514
https://doi.org/10.1590/1678-4324-2021210085
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFOP
instname:Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
instname_str Universidade Federal de Ouro Preto (UFOP)
instacron_str UFOP
institution UFOP
reponame_str Repositório Institucional da UFOP
collection Repositório Institucional da UFOP
repository.name.fl_str_mv Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)
repository.mail.fl_str_mv repositorio@ufop.edu.br
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