Borderline personality features possibly related to cingulate and orbitofrontal cortices dysfunction due to schizencephaly.

• Autor(a) principal: Rocha, Felipe Filardi da
• Data de Publicação: 2008
• Outros Autores: Diniz, Leandro Malloy, Sousa, Karla Cristhina Alves de, Cano Prais, Hugo Alejandro, Correa, Humberto, Teixeira, Antônio Lúcio
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFOP
• Texto Completo: http://www.repositorio.ufop.br/handle/123456789/3835; https://doi.org/10.1016/j.clineuro.2007.12.009
• topic: Schizencephaly; Impulsivity; Borderline personality; Orbitofrontal cortex; Cingulate cortex

Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with prominent borderline features and compromise of executive functions, decision-making and attention. We hypothesize that the personality disorder of our patient could be related to cingulate cortex lesion and secondary orbitofrontal cortex dysfunction associated with schizencephaly.