Efeito da suplementação com polpa de macaíba (Acrocomia intumescens Drude) sobre parâmetros bioquímicos, estresse oxidativo e comportamento de ratos exercitados

• Autor(a) principal: Souza, Mikaelle Albuquerque de
• Data de Publicação: 2021
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UFPB
• Texto Completo: https://repositorio.ufpb.br/jspui/handle/123456789/22368
• topic: Natação; Malonaldeído; Ansiedade; Palmeira brasileira; Efeito cardioprotetor; Swimming; Malonaldehyde; Anxiety; Brazilian palm; Cardioprotective effect; CNPQ::CIENCIAS AGRARIAS::CIENCIA E TECNOLOGIA DE ALIMENTOS

Macaíba pulp (Acrocomia intumescens Drude) contains unsaturated fatty acids, in addition to antioxidants, which makes it a consumption option for individuals who practice physical exercise. Thus, the objective of this research was to verify the effects of the consumption of Macaíba pulp on physical, biochemical, oxidative and behavioral stress parameters in exercised rats. For this purpose, 44 rats were used, divided into four groups, with a number of 11 animals each, as follows: sedentary control (CT), sedentary macaw (MC), exercised control (CT-EX) and exercised macaw (MC- EX). The CT and CT-EX groups received, by gavage, distilled water, while MC and MC-EX received, by gavage, macaiba pulp at a concentration of 1000 mg/kg of animal weight. All animals received commercial feed ad labitum. The animals in the CT-EX and MC EX groups were submitted to the exercise protocol, which consisted of a swimming period (free swimming), for a period of eight weeks. In the first week of training, adaptation phase, in which the exercise time followed ascending order, starting with 10 min and daily adding 10 min. At the end of the treatment, all animals were submitted to behavioral tests, using the open field (AC), elevated plus maze (LCE) and light-dark box (CCE) apparatus to verify anxiety parameters. Forty-eight hours after the behavioral tests, the animals were euthanized and the physical parameters were checked, and with the blood collected, biochemical parameters were quantified. With the values of lipoproteins, the cardiovascular risk was verified. The liver was removed and the concentration of malonaldehyde (MDA), total fat, total cholesterol (TC), triglycerides (TG) and histology were evaluated. Heart tissue was removed and MDA quantified. It was considered statistically different when p < 0.05. From the data obtained, it was found that sedentary and exercised animals that consumed Macaíba pulp presented reduced anxiety, with a greater number of ambulation and rearing and shorter grooming time in the CA, they also had a greater number of entries and time spent in open arms, greater number of head dives and less time in closed arms in the CSF. MC-EX still presented a greater number of entries and permanence in the clear part of the CCE. As for the physical parameters evaluated, we found that both MC and MC-EX showed a reduction in weight, with this reduction being more expressive for MC-EX. MC and MC-EX showed a reduction in body fat (mesenteric, retroperitoneal and epididymal), low and very low density lipoproteins, CT, aspartate and alanine aminotransferase, cholesterol, MDA in the heart, in addition to reduced coronary and cardiovascular risks. We still found an increase in HDL in MC and MC-EX. Thus, concluding that the consumption of Macaíba pulp induced anxiolytic, cardioprotective effect, modulated biochemical parameters, in addition to contributing to the reduction of visceral fat.