Study of morphology, physicochemical properties and antibacterial effect of gallium oxide coated implantable substrates submitted to thermal oxidation treatment

• Autor(a) principal: YASEEN, Maria
• Data de Publicação: 2019
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Repositório Institucional da UFPE
• Texto Completo: https://repositorio.ufpe.br/handle/123456789/35812
• topic: Engenharia Elétrica; Implante biomédico; Biomaterial; Óxido de gálio; Filme fino; Oxidação térmica; Antibacteriano

In the production of medical devices, surface modification of bioimplant is a key process to link with the biointerface for each other. Many strategies, however, implement a multi-functional approach that incorporates with the suitable deposition thin film growth and antibacterial coating mechanisms. Surface coating approach not only projected as protection layer but also justify with the less use of bulk material and expense. In biomedical arena, it‘s assisted as to prevent bacterial adhesion and reduce biofilm formation due to the increasing prevalence of antibiotic resistant bacterial strains. Present work focused on the use of a metal oxide (Gallium oxide) on different substrates to investigate the appropriate condition to prevent bacteria adhesion with and without subtract effect. Two thin film deposition techniques MOCVD and PLD choosed to deals with the certain parameters. For this, deposition technique applied to adhere the thin film of biomaterial on the substrates. After deposition major concern was to improve the surface properties. The interactions of Gallium Oxide (Ga₂O₃) were investigated using multiple characterization techniques. In results, surface features explored by morphology, XRD, surface roughness and wettability characterization. The diffraction peaks are indexed as with the crystalline structure which is confirmed by X-ray diffraction pattern. Further, interface behaviour study under different substrates effects coated with gallium oxide. It must be concluded that as surface treatment temperature approached to deposition temperature RMS values became equal or greater and thermal treatment under vacuum condition support good treated surface. From adhesion point of view, all surfaces uniquely hydrophilic with the gallium oxide thin film metal oxide. Through, antibacterial assessment of gallium oxide revealed more effectives on the E. coli bacterial cells the S. aureus. It was perceived that the coated surfaces possess strong different electrical properties and thus illustrate more efficient electron transfer mechanism with the Ti alloy when compared with the other surfaces counterpart. The death kinetics of bacteria with multiple coating surfaces was provided the surface potential in the design of medical devices. By the manipulation of band theory with charge transportation phenomena support to in the selection of suitable implant surface. Moreover, metal substrate surface with the metal oxide thin film provide promising results to modify the biomedical implant for as antibacterial coating.